소뇌 소경색의 임상 양상과 발병 기전

정산 대한뇌졸중학회 2001 Journal of stroke Vol.3 No.2

Background : In the cerebellum, small(〈2 cm in diameter)infarcts have recently been reported as having different pathogenic mechanisms from supratentorial small ischemic lesions. However, it is unclear only with simple MRI or conventional CT scan whether they are lacunar infarcts or borderzone infarcts. The purpose of this study was to elucidate the pathophysiological mechanism and the clinical nature of small cerebellar infarcts. Methods : We analyzed consecutive patients admitted to the Hallym stroke center between 1994 and 1999. Among them, we selected ischemic cerebellar stroke and classified them into large territorial, small non-territorial and mixed types according to their infarct sizes. We studied clinical and MRA findings and pathogenic mechanisms in each type of the cerebellar infarcts. Results : Forty-seven patients were selected for the study. Twenty-one cases were classified as large territorial infarcts, 18 patients as small non-territorial cerebellar infarcts. The Mixed form included 8 patients. Patients with large territorial infarcts and those with small cerebellar infarcts had similar risk factors, laboratory findings and clinical features. As for the causative mechanisms, small cerebellar infarcts had similar proportion of large artery disease(66.7% vs. 55.7%) and cardiac embolic source(16.7% vs. 28.6%) when compared to large territorial infarcts. Conclusion : Although the radiologic findings of small cerebellar infarcts resemble supratentorial lacunar lesion, the small cerebellar infarcts have heterogenous etiologies. Diagnostic studies and management of small cerebellar infarcts should be based on the understanding of these observations. Korean Journal of Stroke 2001;3(2): 124~130

생약추출물이 Aspergillus parasiticus의 Aflatoxin B1 생성에 미치는 영향

정산진 한국약용작물학회 2003 韓國藥用作物學會誌 Vol.11 No.5

The influences of the extracts from Cinnamomi cortex, Eucommiae Cortex, Puerariae Radix, Lycii Fructus, Zixyphi Fructus, Schisandrae Fructus, Mume Fructus, Chaenomelis Fructus on mycelial growth and aflatoxin B1 production from Aspergillus parasiticus were analyzed. The pH of the culture media were redeced to below pH 4 by all the herbal extracts after 3 days incubation. However, the pH of the culture media increased above pH 6 after 6 days incubation using the extracts from Cinnamomi Cortex, Eucommiae Cortex, Puerariae Radix and Lycii Fructus. The mycelial growth of A. parasiticus was increased over the amount of the control. Puerariae Radix produced the largest amount of mycelial growth and Chaenomelis Fructus produced the smallest amount of mycelialgrowth. The productions of aflatoxin B1 from A. parasticus culture were increased by the extracts of Puerariae Radix and Zizyphi Fructus, while inhibited by the extractso of Cinnamomi Cortes, Eucommiae Cortex, Lycii Fructus, Schisandrae fructus, Mume Fructus and Chaenomelis Fructus. In particular, the extracts of Cinnamomi Cortex, Lycii Fructus and schisandrae Fructus almost inhibited the preduction of aflatoxin b1. The production of the total protein from Cinnamomi Cortex, which produced much less aflatoxin B1, and Puerariae Radix, whichproduced a great deal of aflatoxin B1 from A. parasticus were slightly higher than the production of the total protein of the control medium.

Relationship between Cognitive Impairment and Depression in Dialysis Patients

정산,이영기,최선령,황성희,노정우 연세대학교의과대학 2013 Yonsei medical journal Vol.54 No.6

Purpose: Patients with chronic kidney disease frequently show cognitive dysfunction. The association of depression and cognitive function is not well known in maintenance dialysis patients. We evaluated cognitive impairment and depression, as well as their relationship in regards to methods of dialysis, maintenance hemodialysis (MHD) and chronic peritoneal dialysis (CPD). Materials and Methods: Fifty-six maintenance dialysis patients were recruited and their clinical and laboratory data were collected. The Korean version of the mini-mental state exam (K-MMSE) was applied to screen the patient’s cognitive function, while the Korean version of the Beck Depression Inventory (K-BDI) was used for depression screening. Results: The average age of the participants was 54.2±10.2 years; 29 (51.8%) were female. The average dialysis vintage was 4.2±3.8 years. The CPD group showed significantly higher K-MMSE score (27.8±2.9 vs. 26.1±3.1, p=0.010) and lower K-BDI score (12.0±8.4 vs. 20.2±10.4, p=0.003) compared with the MHD group. The percentage of patients with depression symptoms was higher in the MHD group (51.7% vs. 18.5%). There was a negative correlation between cognitive function and prevalence of depressive symptoms. Depression and education level were shown to be independent predictors for cognitive impairment in multivariate analysis. Conclusion: Cognitive impairment was closely correlated with depression. It is important to detect cognitive impairment and depression early in maintenance dialysis patients with simple bedside screening tools.

소셜 빅데이터 분석을 활용한 한국 야구 국가대표팀에 대한 인식 분석 : 2023 월드 베이스볼 클래식(World Baseball Classic)을 중심으로

정산,오응수 한국스포츠학회 2023 한국스포츠학회지 Vol.21 No.3

This study aims to understand the overall perception of the South Korean national baseball team in the 2023 World Baseball Classic (WBC) and provide insights for improving public perception and marketing strategies for the WBC tournament. Using the TextoM big data processing solution, various analyses were conducted on data collected from Naver, Daum, and Google during different WBC phases. The research findings are as follows: Firstly, keyword analysis revealed that before the WBC opening, the predominant keywords revolved around information about the South Korean national baseball team, training, broadcasting, while during the WBC tournament, the focus shifted to participating countries, players, match schedules, and results. After the WBC's conclusion, keywords were related to tournament information, the start of the professional baseball season, and team performance issues. Secondly, network visualization and CONCOR analysis unveiled distinct groupings during different phases. Prior to the WBC opening, there were four groups comprising the South Korean national baseball team, WBC match issues, training, and commentary. During the WBC tournament, five groups emerged, including the South Korean national baseball team, WBC match issues, match results, WBC opening, and national team retirements. After the WBC's conclusion, four groups surfaced, involving the South Korean team's performance, downturn, Asian Games preparation, and match issues. Based on these results, this study aims to contribute to public perception analysis research and the development of the domestic sports industry by suggesting improvements in public perception and WBC activation strategies.

Donepezil 복용 후 발생한 구음장애

정산,백종삼 대한신경과학회 2001 대한신경과학회지 Vol.19 No.2

주․야 경관에 따른 진정성과 관광만족의 차이분석 -고궁관광을 중심으로-

정산설,이훈 한양대학교 우리춤연구소 2019 우리춤과 과학기술 Vol.15 No.3

As the tourism activity of tourists increases at nighttime, the importance of experience is rising in the night scenery of cultural heritage buildings. Due to the economic and cultural importance of the tourism phenomenon that experiences the night scenery focusing on the spatial background of cultural heritage sites, many domestic and international scholars are paying attention to research subjects related to night view in various fields. However, there is a lack of research on night scenery in the field of tourism. The purpose of this study is to analyze the difference of causality between authenticity and tourism satisfaction with tourists who viewed day and night scenery of cultural heritage site. The subject of this study is Deoksugung Palace located in Seoul, Korea. Deoksu Palace is open all the time at night, and this place is expected to be the best place to analyze the difference of day scenery and night scenery in cultural heritage. First, both sub-dimensions of authenticity positively influenced tourism satisfaction, Objective authenticity has a more significant effect than existential authenticity. Second, the results of analyses show that there is moderating effect on authenticity and tourism satisfaction according to the experience of day scenery and night scenery. In other words, this implies that objective authenticity in the experience of day scenery and night scenery shows the influence difference in tourism satisfaction. This study is to contribute to the sustainability of cultural heritage tourism related to night scenery while suggesting academic and practical implications. It can be meaningful to quantitatively validate the relationship between authenticity and tourism satisfaction about landscape experience that has been mainly approached qualitatively in other fields. The purpose of this study is to investigate the causal relationship between objective authenticity and tourism satisfaction in the cultural tourism of day and night. This emphasizes the importance of night scenery and provides an opportunity to utilize it as a major element of tourism marketing.

스마트 관광기술 경험이 확장된 기술준비수용모델 및 주관적 행복에 미치는 영향

정산설(San-Seol Jung),이훈(Hoon Lee) 한국관광학회 2024 관광학연구 Vol.48 No.2

과학기술의 발달과 4차 산업시대의 도래로 관광도 역시 급격한 시대 변화가 나타나고 있다. 신기술의 발전으로 관광 역시 국내외에서 스마트 관광 원활화를 위한 정책을 수립하고 있으며, 관련한 연구가 지속해서 배출되고 있다. 하지만 관광에서 스마트 기술의 도입은 공급자 관점의 기술 연구와 경제적인 이윤 중심 연구가 주류를 이룬다는 한계가 지속해서 지적되고 있다. 따라서 이 연구는 ‘확장된 TRAM 모델’을 활용하여, 관광자 입장에서 스마트 관광 환경 구축에 중요한 요인이 무엇인지 확인하고, 기존에 신기술 도입이 관광자의 행복 지각에 어떤 영향을 주는지 실증분석을 통하여 미래형 스마트 관광의 지향점을 설정하고자 한다. 이 연구는 여행에서 스마트 관광기술을 활용한 내국인 관광자를 대상으로 설문조사를 실시하였고, 420개의 유효 응답을 토대로 분석을 진행하였다. 분석방법은 구조방정식 및 랜덤포레스트 분석 방법을 활용하였다. 분석 결과, 기술준비도 변수 중 혁신성을 제외하고 모두 유용성에 유의미한 영향을 미쳤으며, 기술준비도 변수 중 낙관성을 제외하고 모두 용이성에 유의미한 영향을 미쳤다. 용이성과 유용성의 영향관계는 채택되지 않았으나, 유용성-주관적 행복 및 용이성-주관적 행복의 관계는 유의미한 정(+)의 영향력이 있음이 확인되었다. 랜덤포레스트 분석 결과, 유용성 및 유희성이 스마트 관광기술이 관광자의 주관적 행복을 높이는 데 중요한 변수임이 확인되었다. 따라서 스마트 관광기술 경험은 관광활동에 대한 전반적인 유용성 및 용이성을 높여주며, 주관적인 행복 향상에 기여하고 있음을 알 수 있다. 이와 같은 결과를 바탕으로 관광자가 스마트 관광기술을 통해 추구하는 본질적인 요구가 무엇인지 이해할 수 있다. 실무적으로는 스마트 관광의 경쟁력을 제고 할 수 있는 관광 정책 전략의 기반을 제공할 수 있다. Recent technological advancements have rapidly reshaped the tourism landscape, leading to an increased focus on smart tourism research and the development of global smart tourism policies. However, existing literature predominantly addresses technological and economic aspects from suppliers' perspectives, often overlooking tourists' experiences. This study adopts the 'extended TRAM model' and empirically explores key factors influencing a smart tourism environment for tourists and their impact on happiness perception. By surveying 420 domestic tourists using smart tourism technology, the analysis employs structural equation modeling and random forest analysis. The results reveal that all five technological readiness variables, except innovativeness, significantly affect tourists' perceptions of the technology's usefulness in simplifying their travel. Similarly, all variables, with the exception of optimism, notably impact the perceived ease of use, indicating the level of difficulty tourists face when employing the technology. Although perceived ease of use and perceived usefulness are not directly related, both demonstrate a positive association with subjective well-being. The random forest analysis underscores the importance of perceived usefulness and enjoyment in enhancing tourists' subjective well-being through smart tourism technology. These findings illuminate essential tourist needs and provide practical insights for marketing strategies in smart tourism technology.

제 3상 임상시험을 위한 연구 대상수 산출:로그순위 검정법의 적용

정산호,최재희외1명 한국역학회 1997 Epidemiology and Health Vol.19 No.1

CNN 기반 아보카도 숙성도 분류

정산아(San ah Jeong),조은수(Eun Soo Cho),정호기(Ho Gi Jung) 대한전자공학회 2022 대한전자공학회 학술대회 Vol.2022 No.11

Avocado, which is used in various diet foods, has been listed in the Guinness Book of World Records as the most nutritious fruit in the world as well as teenage superfoods. Avocado is a fruit that requires post-aging, so it was often difficult for consumers to know if post-aging was completed. Previously, research has been conducted to determine the maturity of avocados using electrodes. However, in this study, the goal is to implement an algorithm that determines whether avocados have matured when consumers photograph them using a camera. The dataset was actually collected by taking about 2600 photos of avocados in the categories of ripe, unripe, and rotten, and a convolutional neural network (CNN) based network was trained. As a result, it was confirmed that about 72% of the accuracy was shown.

기술시대 지역정신을 존중하는 현대경관설계 : 북경사계스키장 경관계획 사례

丁山,이기철,박승범,남정칠,김승환,강영조 東亞大學校 建設技術硏究所 2007 硏究論文集 Vol.30 No.2

The Four-Season ski resort which is prepared for 2008 Beijing Olympic project is the biggest indoor ski-dome. The fundamental concept for landscape design is to harmonize the development of Beijing city via the construction of modern building, the culture of China and Olympic spirit. Thus, the concept is evolved from the satisfaction of public, the realization of ecology and the site-of-art technique. The project requires the value of regional spirit when carrying out the planning of landscape. Thus, the starting point of design is evolved from the respect for nature, humanism, culture, sustainable development of city and ecosystem.