고 무기질 음료(π-water) 섭취시 럭비선수들의 근력, 근 지구력 및 유산소성 운동능력에 미치는 영향

손두옥,선우섭,윤우상,유재충,박영진,오종환 경희대학교 사회체육연구소 1996 體育科學論叢 Vol.- No.9

Most of elite sports player during the sports competing and trainning have used the mineral supplements to enhance on the human performance and, also a number of researcher have recommended the mineral supplements of RDA(Recommended Dietary Allowance) for them. However, It has not exactly known to the scientific interpretation and evidences of relationship between human performance and mineral. Thence, The purpose of this study was to prove whether the mineral supplements of high RDA could enhance the sport player's performance or not The subjects of this study were composed of sixteen Rugby football players(experimental group=8, high density multimineral water intake for 30days; control group=8, placebo intake)in K-H University. Both of groups were tested three times(pre=before intake, mid=after 15days supplements, post=after 30days supplments) about maximum anaerobic power(MAnp) and maximum oxygen uptake by bicycle ergometer(868), muscle strength and muscle endurance by isokinetic Cybex system(350). The statistical analysis employed this study was t-test by statistic 512+ program in machintosh computer. The result of this study were appeared that the difference in control and experimental group signified that the experimental group was high more than the control group in left knee extensor's peak torque at mid-test(P<.05), in left knee extensor's total work(%BW) at mid-test(P<.05), in left extensor's average power and average power(%BW) at mid-test(P<.05). Relative maximal oxygen uptake(㎖/LBMkg/min) in experimental group was higher than control group after 30 days the mineral supplements. These results suggest that the high density multimineral water intake should influence partially rugby football player's performance by the increment of muscle endurance and maximal oxygen uptake.

A. 高校 科學 (生物·地球科學) 및 數學科 探究學習의 評價模型 定立과 評價紙 開發

李相協,權炳奎,林在圭,孫文求,吳岱燮,楊洪準,梁承榮,姜用熙,林成圭,金正遠,金吉民,兪正在 경북대학교 과학교육연구소 1982 科學敎育硏究誌 Vol.6 No.-

Currently the evaluation of high school science and mathematics learning has been too much knowledge-centered without concerning the inquiring ability or scientific attitude. This study, therefore, was made for the purpose of establishing of evaluation model for high school science (biology and earth science) and mathematics learning and its evaluation items. In this paper, the research was done about three fields, biology, earth science and mathematics. 1. For the biology, the evaluation methods of inquiry learning were studied with the foreign references, and proper evaluation items were suggested. 2. For the earth science, after analizing 5 kinds of earth science textbook of current using in high school, essential 19 items were selected. 5 of them were tested in test group and control group, then, the results were analized. 3. For the mathematice, the teaching elements of「Set」and「Flow chart」in mathematics (Ⅰ) were selected and structured. Detailed teaching objects were established and evaluation items were introduced.

대뇌 피질 신경 세포 일차 배양에서 6-hydroxydopamine에 의한 신경세포사멸의 특성

정재훈,강효정,손성향,정영기,곽병주,노재성 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.3

연구목적 : 본 연구는 생쥐 태자 대뇌 피질 세포 일차 배양에서 파킨슨씨병의 동물 모델을 만드는데 사용되는 신경독성 물질인 6-hydroxydopamine(6-OHDA)에 의한 신경세포 사멸의 특성을 관찰한 것이다. 방 법 : 생쥐태자의 신경세포를 배양하여 6-OHDA를 처리하고 이와 더불어 여러가지 신경세포 사멸에 영향을 주는 물질을 투여하여 신경세포의 사멸을 정량적으로 분석하고 형태학적 분석을 전자현미경을 통하여 관찰하였다. 결 과 : 배양한 신경세포에 6-OHDA를 처리하면 투여 양에 비례하여 신경세포의 사멸이 증가하여 50μM 66-OHDA를 24시간 투여하여 일으킨 신경세포 사멸의 형태학적 특징은 세포질의 수축 및 염색질의 응축(nuclear chromatin condensation) 및 핵질의 fragmentation을 동반하는 고사(apoptosis) 형태이다. 이 때의 신경세포의 사멸은 항고사 물질인, 1㎍/ml cycloheximide와 caspase 억제제인 10μMzVAD-fmk에 의해 약화되었으나 글루타메이트 길항제(10μM MK-801 혹은 50μM CNQX)나 항산화제 (100μM trolox 혹은 100μM N-acetyl-cysteine)는 6-OHDA에 의한 신경세포의 사멸을 막지 못했다. 결 론 : 이상의 형태학적 및 약물학적 특징은 6-OHDA가 고사성 신경세포 사멸을 유도한다는 것을 의미하고, 항산화제들이 효과가 없다는 것과 caspase 억제제가 보호효과가 있다는 것은 6-OHDA에 의한 고사성 신경세포 사멸에는 산화적 스트레스보다는 caspase cascade와 관여된 기전이 기여한다는 것을 시사한다. 또한 6-OHDA에 의한 신경세포의 사며른 도파민성 신경세포에 선택적이지 않으며, 일차 대뇌피질 신경세포 배양 시스템이 6-OHDA에 의한 신경세포사멸인구에 사용될 수 있음을 보여준다 Objectives : We examined the patterns of cell death induced by the 6-hydroxydopamine, a selective dopaminergic toxin that used to produce Parkinson's disease model. Method : Neocortices from 14 - or 15-day-old fetal mice for neuron-glia co-cultures were used for this experiments. Results : Cortical cell cultures exposed to 10-100μM 6-hydroxydopamine for 24 hr underwent neuronal death without injuring glia. The degenerating neurons showed hallmark of apoptosis featuring cell body shrinkage, nuclear chromatin condensation and aggregation, nuclear membrane disintegration with intact plasma membrane, and prominent internucle- osomal DNA fragmentation. Neither the glutamate antagonists (10μM MK-801 and 50μM CNQX) nor antioxidants(trolox, 100μM, N-acetyl-cysteine, 100μM prevented the 6-OHDA induced neuronal injury. The death was attenuated by addition of two different anti-apoptotic agents, 1㎍/ml cycloheximide and caspase inhibitor(100μM zVAD-fmk). Conclusion : These features suggest that 6-OHDA induced apoptotic type of neuronal death in cortical neuronal culture. Considering the protective effect of caspase inhibitors, a mechanism involing caspase cascade rather than oxidative stress is responsible for the 6-OHDA-induced neuronal apoptosis. In addition, our results showed that 6-OHDA-induced apoptosis is not confined to dopaminergic neurons and the primary cortical culture system so this system is suitable for the study of 6-OHDA-induced neuronal apoptosis.

완전 탈구된 치아의 재식에 대한 증례보고

이제호,최병재,손흥규,조우성 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.3

The treatment of complete avulsed teeth due to traumatic injuries is replantation procedure. The major complication of replantation are pulp necrosis, ankylosis, and root resorption. It is important to maintain the vitality of periodontal ligament to minimize the complications. The purpose of this case report is to consider the facts that affect the success rate and the prognosis of complete avulsed teeth replantation. All of these cases had different conditions and transport media. The followng results were observed : 1. The successive treatment of complete avulsed teeth requires the maintainance of vitality of periodontal ligament. 2. The complication of replantation are inflammatory root resorption and ankylosis and in such case, proper endodontic treatment using calcium hydroxide medications and periodic observations are needed. 3. In case of delayed replantation, the use of fluoride and root planning procedure can help to achieve better result. 4. It is more esthetic and functional to maintain the avulsed tooth in mouth.

개선된 Bridgman법으로 성장한 Bi₂Sr₂CaCu₂O_(8+δ) 單結晶의 초전도성

채건식,손인호,설정식,이수대,김영국,전동성,오재근,강성욱 경남대학교 환경문제연구소 1995 환경연구 Vol.17 No.-

The Bi₂Sr₂CaCu₂O_(8)+_(δ) single crystals are grown from the melt using a stoichiometric starting composition fer the cautions. The size and thickness of the Bi₂Sr₂CaCu₂O_(8)+_(δ) crystals depends on the cooling rate. The lower the cooling rate, the bigger and thicker the Bi₂Sr₂CaCu₂O_(8)+_(δ) crystals become. Bi₂Sr₂CaCu₂O_(8)+_(δ) X-ray diffraction(XRD) measurements of the single crystals were carried out using the radiation source of Cu Kα . In these Patterns only the (0,0,2n) diffraction appeared. The result indicated that the cleared surface of the single crystal was of the a-b face, and that the single crystal had a single phase without any undergrowth with 7K and 85K phases. In addition, although the figure is not shown, XRD patterns from (006) to (00□) were observed in the range of 2θ=0 to 60 degrees. The characterization of as-grown single crystals have been analyzed by Laue X-ray backsdattering along the c-axis and X-ray precession experiments. The result of magnetic moment vs Tc in 10 Gauss for a crystals were measurements indicated that the samples have a superconducting transition temperature of 85K.

본태성 고혈압에서 염산에포니디핀 (NZ-105, 핀테20정�)의 유효성 및 안전성 : 제3상 다기관 임상시험 The phaseⅢ multicenter open trial

배종화,손일석,강흥선,조정휘,강재헌,김성원,이선영,양윤준,김영식,선우성 대한간질학회 2003 대한간질학회지 Vol.9 No.1

매복치의 외과적 노출에 대한 임상적 연구

김지연,김재덕,백종성,손경준 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

Impaction and ectopic eruption of Permanent teeth can cause various clinical Problems. These teeth are not hopeless. It is possible to use the remaining teeth as anchorage, surgically uncover the impacted tooth, and orthodontically move the tooth into the arch. The specific surgical procedure and the orthodontic mechanics, however, will vary depending upon the type of tooth and its position relative to the remaining erupted teeth. There are different surgical techniques for the surgical exposure of the impacted teeth. These case reports described the surgical exposure using the apically positioned flap(APF) and closed eruption technique ,

제2배부 중수골 유경 혈관 이식과 일시적 삼중 주상골 고정에 의한 Kienböck 질환의 치료

서재성(Jae-Sung Seo),손욱진(Oog-Jin Shon),한재형(Jae-Hyeung Han),박삼국(Sam-Kuk Park),고진혁(Jin-Hyuk Ko),정승민(Sung-Min Chung) 대한정형외과학회 2006 대한정형외과학회지 Vol.41 No.4

목적: Kienbock 질환 치료에 있어 월상골의 재혈관화를 위한 유경혈관 이식술은 유용한 치료법의 하나로 알려져 있다. 이에 저자들은 Kienbock 질환 환자에서 유경 혈관 이식 및 일시적 삼중 주상골 고정술의 결과와 예후를 알아보고자 하였다. 대상 및 방법: 1999년 3월부터 2003년 5월까지 Kienbock 질환으로 유경 혈관 이식 및 일시적 삼중 주상골 유합술을 받은 9명의 환자를 대상으로 추시 관찰하였다. 추시 기간은 15개월에서 54개월로 평균 35개월이었고 수술 당시 2명이 Lichtman stage Ⅱ, 6명이 stage Ⅲa, 1명이 stage Ⅲb였으며 모든 환자에서 척골 중립변위였다. 수술은 요골 동맥의 제2배부 중수골 분지와 동반 정맥을 이용한 유경 혈관 이식 및 일시적 삼중 주상골 고정술을 시행하였다. 결과: 요측 편위를 제외한 술 후 운동범위와 악력은 유의하게 증가하였다. 이전의 직업으로 복귀하는데 걸린 시간은 평균 22주였다. 단순 방사선 검사상 경화가 호전되는 소견은 8예에서 보였으나 월상골의 함몰 이 6예에서 증가된 소견을 보였다. Lichtman의 기준에 의한 평가는 7예에서는 만족, 비교적 고연령인 2예에서는 불만족이었으며 Nakamura 평가법에 의하면 5예에서 양호, 3예에서 보통, 1예에서는 불량이었다. 결론: 척골 중립변위인 Lichtman stage IIIa 이하의 Kienbock 질환 환자에서 일시적 삼중 주상골 고정술을 동반한 유경 혈관 이식술은 시도할 만한 가치가 있는 치료법이다. 하지만 재혈관화 술식 시 환자의 나이를 고려해야하며 향후 일시적 삼중 주상골 고정의 기간에 대한 체계적인 연구가 필요할 것으로 생각된다. Purpose : Revascularization is a useful method for treating Kienbock's disease. The aim of this study was to evaluate the use of the second dorsal metacarpal vascular pedicle to treat Kienbock's disease. Materials and Methods : A retrospective study was carried out on 9 patients who had undergone vascular pedicle graft for Kienbock's disease between 1999 and 2003. The mean follow up period was 35 months. At the time of surgery, 2 patients were graded as stage Ⅱ, 6 as Ⅲa and 1 as Ⅲb. The ulnar variance was neutral in all cases. A vascular pedicle graft using second dorsal metacarpal vessel were performed and temporary scaphotrapeziotrapezoid (STT) fixation were applied for 6 months. Results : Wrist motion except for the radial deviation and grip strength had improved significantly. The patients returned to work after an average of 22 weeks. Resorption of the sclerosis was observed in 7 cases, but lunate collapse was observed in the simple radiograph in 6 cases. According to Lichtman's criteria, 7 cases were satisfactory but 2 cases with a relative old age were unsatisfactory. According to Nakamura's classification, 5 cases were good, 3 cases were fair and 1 case was poor. Conclusion : In Kienbock's disease with neutral ulnar variance, a revascularization procedure of vascular pedicle graft with temporary STT fixation is a good treatment method but the patient's age should be considered when determining the revascularization procedure. A prospective study will be needed to determine the optimal duration of temporary STT fixation.

성인 상부위장관 질환군에서의 H . pylori 검출에 이용되는 검사법의 상호비교

한길성(Gil Sung Han),서대규(Dae Gyu Seo),신왕식(Wang Sik Shin),정재군(Jae Gun Jung),손호상(Ho Sang Shon),최정윤(Jung Yoon Choe),안기성(Ki Sung Ahn),배정동(Jung Dong Bae),박재복(Jae Bok Park),강민모(Min Mo Kang) 대한소화기학회 1996 대한소화기학회지 Vol.28 No.1

N/A Background/Aims: For the evaluation of recent reports that H. pylori infection plays a causative ro1e in the pathogenesis of upper gastrointestinal diseases, we studied the relationship between the presence of H. pylori infection in patient and asymptomatic volunteer groups, using histologic demonstration of the bacteria, CLO test, and serum H. pylori antibody titer. Calculation of sensitivity, specificity, and predictive value of CLO test and antibody detection rate in relation to histologic demonstration were also performed. Methods: We evaluated the detection rate of H. pylori infection by direct demonstration with special stain, CLO test, and IgG antibody titer by EIA method in 80 symptomatiq patients who were categorized by endoscopic findings into 24 patients with chronic gastritis, 22 patients with gastric ulcer, 20 patients with duodenal ulcer, 14 patients with gastric cancer, and 20 asymptomatic volunteers. Four or more biopsy specimens of gastric and duodenal mucosa were taken from each of the total 100 cases with gastrofibroscopy and then blood samples were also taken. Results: In sections stained by Warthin-Starry method, H. pylori was found 62.5% in the 80 patients group and 30.0% in the 20 asymptomatic volunteers group. The prevalence of H. pylori was the highest in gastric cancer group(71.4%). The prevalence of H. pylori in the patients with peptic ulcer and gastric cancer was significantly higher than the asymptomatic volunteer group(p0.05). Positive CLO test in the patient group was 77.5% and 35.0% in the 20 asymptomatic volunteers group. The positive rate was the highest in gastric cancer group. The positive rate of the CLO test in patients with peptic ulcer and gastric cancer groups was significantly higher than the asymptomatic volunteer group(p0.05). The positive rate of IgG antibody test in the patient group was 82.5% and 45% in the 20 asymptomatic volunteer group. The rate of positivity was the highest in duodenal ulcer group. The positive rate of the serum IgG antibody test in all patient groups was significantly higher than asymptomatic volunteer group(p 0.05). Sensitivity and specificity of CLO test and IgG antibody test in relation to direct H. pylori smear was 94.6%, 76.7%, 96.4%, and 53.47o respectively. Conclusions: The positive rate of the H. pylori infection in patients with peptic ulcer and gastric cancer groups was significantly elevated compared with control and chronic gastritis groups for each of the 3 tests. For clinical purpose, CLO test can be used as a single guide for the treatment of H. pylori infection for its rapidity and efficacy. (Korean J Gastroenterol 1996;28: 19 - 27)

Gamma-Ray Burst Observation by SNIPE mission

Jae-Jin Lee,Hong Joo Kim,Uk-Won Nam,Won-Kee Park,Jongdae Shon,Soon-Wook Kim,Jeong-Sook Kim,Yong-Woo Kang,Z. Lucas Uhm,Sinchul Kang,Sang Hyeok Im,Sunghwan Kim 한국천문학회 2020 天文學會報 Vol.45 No.1