Alloxan 유발성 당뇨쥐에서 혈장의 지질과산화 및 항산화효소에 미치는 Caffeic Acid의 영향

南昌祐,黃成姬 同德女子大學校 1992 同大論叢 Vol.22 No.1

This research was aimed to investigate the effect of caffeic acid on lipid peroxidation and antioxidative enzymes in alloxan induced d·i·acetic rats. The first group was administrated to intraperitoneal with alloxan to induce the diabetic mellitus, the second and third group was inhected with thiourea and caffeic acid before alloxan injection, respectively. The physiological saline solution was treated as control. At 24, 48 and 72 after treatment, the levels of lipid peroxide in plasma were estimated and the activities of supeoxide dismutase, catalase and glutathione peroxidase in the erythrocyte were also evaluated. The results obtained were summarized as fallows ; 1. The lipid peroxide level of plasma in alloxan group showed higher than that of other groups. But there was no significant difference among thiourea, caffeic acid and control group. 2. The activities of superoxide dismutase of erythrocyte in alloxan group was significantly higher than the all other groups at 24 hours and 48 hours after injection but showed no significant difference at 72 hours. 3. There was no significant difference in activities of catalase and glutathione peroxidase of erythrocyte between all gorups.

Cds-Cu₂S thin film에 대한 photoresponse

南尙熙 대구보건대학 1983 대구보건대학 論文集 Vol.7 No.-

The measured Values of the Voc and Isc as a relative light intensity the spectral photo response made by using Vaccum-evaporated Cds-Cu₂S this film. The spectral photoresponse peak was observed at the wave length longer than the wave length corresponding to a band gap of Cds-Cu₂S. The spectral photo response compared to work which has been done based on the Cds-Cu₂S single crystal material.

MWPC 위치검출기의 X-선 천체물리학에의 응용

남욱원,최철성,문신행,강희동 경북대학교 센서기술연구소 1990 센서技術學術大會論文集 Vol.1 No.1

1983 년경 국내에서도 과학탐사 로케트와 인공위성이 발사될 예정에 있으며 이에 따라 X-선 천체물리학을 위한 방사선 센서의 국내 개발이 시급히 요청되는 바이다. 따라서 현재 방사선계측에 많이 이용되고 있는 방사선 센서들 중 국내에서 개발되어온 MWPC위치검출기를 소개하고 인공위성 혹은 과학탐사로케트에 탑재되어 X-선 천체물리학연구에 이용될 경우 연구 개발되어 나가야 할 방향을 제시하고자 한다. Domestic sounding rocket and scientific satellite are scheduled to launch around 1993. The development of radiation sensor is required to observe X-rays coming from celestial bodies by the use of those space vehicleS. In this study we introduce the multi-wire position sensitive detector and the future works of onboard detector for X-ray astrophysics.

컴퓨터를 이용한 순환기내과 학습내용 평가 시스템 개발

남상아,김명희 이화여자대학교 사범대학 교육과학연구소 1999 교육과학연구 Vol.29 No.-

電算化 斷層撮影像에 關한 畵像 再構成法의 數理學的 考察

南尙熙,宋在寬,趙準錫 대구보건대학 1981 대구보건대학 論文集 Vol.5 No.-

The basic principle behind computed tomography is that the internal structure of an object can be reconstructed from multiple projections of the object. The mathematical methods is to produce an accruate cross-sectional display of the linear attenuation coeffidients of each element in the image matrix. This mathematical methods of image reconstruction are described : 1. Back-projection (Sumation method) 2. Iterative methods(Algebraic reconstruction tehnique) 3. Analytical methods (Fourier transformation) We will only attempt a pictorial explanation of the two popular analytic methods, which are two - dimensional fourier analysis and filtered back projection. The basic of fourier analysis is that any function of time or space can be represented by the sum of various projection data. This type of mathematical manipulation is easily and quickly processed in a computer. The reconstruction is a little more complex for a two-dimensional image such as a CT, but the basic principle is the same.

제품생산자동화를 위한 로봇제어

남부희,이상재,이석원 강원대학교 석재복합신소재제품연구센터 1996 석재연 논문집 Vol.1 No.-

본 연구에서 신경망 회로를 이용하여 토크계산제어기를 갖는 로봇 매니퓰레이터의 비선형성과 불확실성을 보상하는 제어기를 설계한다. 여기서 사용한 신경망 회로는 앞되먹임구조의 자율학습을 하는 제어기이며 Ishiguro등이 제안한 학습 데이터가 필요로 하는 감독학습 방법의 보상기제어기 구조보다 간단하다. In this research we research the controller using neural network to compensate for the nonlinearities and uncertainties of the robotic manipulators with the computed torque method. This neural network is used as the feed forward controller which is trained on-line by unsupervised learning and is simpler in the control scheme than the neural network controller proposed by Ishiguro et al. which needs the teaching signals of the neural network compensators and whose learning is supervised.

원발성 중추신경계 임파종 : 치료 및 생존율 Treatment and Survival Rate

남도현,이상형,김동규,정희원,지제근,왕규창,김현집,최길수,한대희 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.3

The authors report on 17 patients having primary central nervous system(CNS) lymphomas between January, 1981 and August, 1992. All patients were treated at Seoul National University Hospital. Only three cases underwent surgery only and fourteen cases underwent surgery and radiation therapy with or without chemotherapy. There were no immunosuppressive patients. Sixteen patients were analyzed for survival studies, because one case was lost during follow-up. The median survival time(MST) was 26 months and one- and two-year survival rates for the 16 patients were 87.5% and 65.6% respectively. The rate of survival was analyzed according to possible prognostic factors ; age and sex, multiplicity and location of tumors, preoperative Karnofsky performance score(KPS), pathological subclassification, type of surgery, preoperative steroid therapy, postoperative adjuvant therapy, extent of radiation, chemotherapy and the degree of response to treatment at three months follow-up. Postoperative adjuvant therapy and the degree of response to the treatment correlated with survival. Fourteen patients who underwent postoperative adjuvant therapy had a median survival time of 63 months. The one- and two-year survival rates were 100% and 75% respectively compared to the MST of 1.5 months with survival rates of 0% and 0% retrospectively for the two patients who did not. A higher long term survival rate was observed in the group with better immediate responses. In nine of 16 patients with complete responses, the MST, one-, and two-year survival rates were 63 months, 100%, and 83% respectively. The authors suggest that preoperative application of steroids may be considered in case of clinically suspected primary CNS lymphomas. It is concluded that after obtaining the tissue diagnosis of primary CNS lymphomas, radiotherapy with or without chemotherapy should be performed until the complete response.

도시주부의 세탁기 사용실태에 관한 조사연구

南相瑀,李載姬 中央大學校家庭文化硏究所 1988 가정문화논총 Vol.2 No.-

This research aims at the effective use of the electric device sparing the housewives the time and trouble in doing home-affairs by investigating the recognition and utility of the washing machine. We took the five factors based on the socio-oppulation-age, education, income, family condition, employment(of the housewives)-as the independent elements and the other factors-posession, recognition and utility of the washing machine-as the subordinate ones. With this supposition We made an attempt to inspect the different and relationship between each other. We chose 470 housewives living in Seoul as an object of this study and thus obtained the reply of them by either the interview or the question and answer sheets. And so the inspection was done by means of the average, percentage, and X²(Chi-Square) test. As a result, [Hyp thesis 1] was partially approved. In other word a noticeable difference was identified in the level of p<.001 with age, education and income and in the level of p<.05 with family condition. [Hypothesis 2] was denied: [Hypothesis 3] was also partially approved. That is to say, in the using frequency of the washer was a noticeable difference identified in the level of p<.05 only with income and family condition, but not identified in case of the utility pattern of the washer. [Hypothesis 4] was approved. A remarkable difference was found out in the level of p<.001 in the relationship between the posession and recognition of the washer. [Hypothesis 5] was approved, too. A marked difference revealed in the level of p<.01 in the relationship between the posession and utility pattern. [Hypothesis 6], A noticeable difference was approved in the level of p<.001 in the relationship between the recognition and utility pattern.

수출용 축양품종 가지의 염절임 공정의 최적화

남학식,김남우,황성희,윤광섭,신승렬 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

가지의 수출 경쟁력 향상을 위한 한 방안으로 수출용 가지품종인 축양품종을 염가공품으로 개발하기 위하여 염절임공정을 최적화하였다. 염절임 시간, 절임온도, 염농도를 독립변수로 하고 절임 후 수분함량, 염도, 표면과 내부의 색도 등을 종속변수로 하여, 중심합성계획법으로 실험을 설계하여 최적조건을 얻고자 하였다. 수립된 이차회귀모형으로 예측식을 수립할 수 있었으며 특히 수분함량이나 염도, 표면과 내부의 L과 b 값에 대하여 높은 적합도를 보여 최적조건을 수립하기 위한 제한 변수로 선정하였다. 염농도를 중심점(30%)에서 고정시켜서 얻은 절임시간과 온도는 각각 5.5~6.5일과 13-17℃였으며, 이때의 종속변수의 제한 요건으로는 수분함량 84%이하, 염도 14%이하 표면 L값 10-20, b값 0이하, 내부 L 값은 70-75, b 값이 16-18이었다. This study was conducted to the optimize salting process of eggplant for development new product and enhancement quality for export. Three variables by five level central composite design and response surface methodology were used to determine optimum conditions for salting time, temperature and salt concentration. Optimization of the process was conducted using the combination of the moisture content, salinity and color of surface and inside of salted eggplant. The regression polynomial model was suitable (P>0.05) by Lack-of-Fit analysis with highly significant. To optimize the process, based on surface response and contour plots, the individual contour plots of the response variables were superimposed. The optimum conditions for this process were 6 days and 15℃ at 30% concentration under the optimum of restricted variables as moisture content was below 84%, salinity was below 14%, L and b value of surface were 10 to 20 and below 0, L value and b value of inside were 70 to 75 and 16 to 18.

흡연 및 비흡연 정신분열증 환자간의 인지 기능과 치료 반응의 차이

남궁기,민성길,이희상,조현상,김세주 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.4

연구 배경 : 본 연구는 정신분열증 환자에서 흡연 여부에 따라 정신분열증 환자군의 정신과적 과거력 및 현재 증상, 치료 반응과 인지 기능 등에 어떤 차이가 있는 지를 알아보려는 것이다. 연구 방법 : 정신분열증 환자 중 36명의 흡연군과 31명의 비흡연군을 연구 대상으로 하였다. 현재의 증상을 평가하기 위해서 양성 및 음성 증상 척도(Positive & Negative Syndrome Scale) 및 전반적 기능 평가 척도(Global Assessment Scale)를 상용하였고, 추체외로계 부작용을 추체외로계 부장용 평가척도(Rating Scale for Extrapyramidal Side Effects)로 측정하였다. 흡연군과 비흡연군의 인지 기능을 평가하기 위해 비엔나 검사 중 SPM(Standard Progressive Matrices), Cognitron 및 FFA(Flicker Fusion Analyzer) 검사를 실시하였다. 연구 결과 : 1) 흡연군과 비흡연군에 비해 유병 기간이 유의하게 길었음에도 불구하고, 입원 시의 증상 정도(PANSS 총점)가 유의하게 낮았고, 기능 정도(GAS 점수) 역시 유의하게 높았다. 2) 정신분열증의 치료 반응에 영향을 미칠 것으로 생각되는 나이와 유병 기간을 통제한 상태에서 흡연여부에 따른 치료 반응의 차이를 검증해 본 결과, 흡연 여부에 따른 일일 약물 사용량, 추체외로계 부작용 및 증상 호전율(PANSS 호전율)이나 기능 호전율(GAS 호전율)에 유의한 차이는 없었다. 또한 인지 기능에 영향을 미칠 것으로 생각되는 나이, 유병 기간, 항전신병약물 용량 및 증상의 정도를 통제한 상태에서 흡연 여부에 따른 인지 기능의 차이를 검증해 본 결과, 흡연 여부에 따른 SPM 값, COG-R 및 FFA 갑의 차이는 없었다. 3) 흡연군 내에서 흡연 정도와 치료 반응 및 인지 검사 점수와의 관계를 알아보기 위해, 나이와 유병 기간 요인을 통제한 상태에서 일일 평균 흡연량과 여러 임상 척도와의 상관 관계를 분석해 보았다. 그 결과 일일 흡연량과 증상 호전율(PANSS 호전율) 이나 기능 호전율(GAG 호전율) 사이에 통계적으로 유의한 상관 관계를 보였다. 그러나 총 흡연 기간은 치료 반응 및 인지 기능과는 통계적으로 유의한 상관 관계를 보이지 않았다. 결 론 : 이상의 결과를 종합해 보면 흡연 정신분열증군은 비흡연 정신분열증군에 비해 입원 시 증상이 경미하고 기능이 좋으며, 흡연 정신분열증군에서는 흡연량이 많을수록 치료 시 증상 및 기능이 호전율이 높다고 할 수 있다. 그러나 흡연군에서 일일 약물 사용량이 높다거나, 추체외로계 부작용이 덜 나타난다거나 지능 저하가 덜하다는 이전의 연구 결과들은 입증되지 않았다. Objectives : The purpose of this study was to examine the differences of past histories, current symptoms, treatment responses and cognitive and functions between smoking and nonsmoking schizophrenic patients. Methods : The subjects were composed of 67 schizophrenic patients including 36 smokers and 31 non-smokers. They were examined by psychiatric history checklist, Simpson and Angus's rating scale for extrapyramidal side effects, positive & negative syndromes scale(PANSS), global assessment scale(GAS), and Vienna test including Standard Progressive Matrices(SPM), Cognitron, and Flicker Fusion Analyzer(FFA). Results : The results were as follows : 1) Although the duration of illness of smokers was longer than that of non-smokers, the smokers had significantly higher score of GAS and significantly lower score of PANSS than non-smokers at admission. 2) With effects of age and duration of illness controlled, there were no differences of mean dosage of neuroleptics, extrapyramidal side effects, PANSS improvement rate and GAS improvement rate between both groups. 3) With effect of age, duration of illness, and total PANSS score controlled, there were no differences of score of SPM, cognitron, and FFA. 4) In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes, with effects of age and duration of illness controlled. Conclusions : In schizophrenic patients, smokers had less severe symptoms than non-smokers. In smokers, the PANSS improvement rate and the GAS improvement rate were positively correlated with mean number of daily smoked cigarettes. But Smokers were not proven to have received higher dosage of neuroleptics, to have lower extrapyramidal side effects, or to have less severe impairment of cognitive function.