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경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염
홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.
Jin‑Kyung Jeon,Hyunseon Seo,Jimin Park,Soo Ji Son,Yeong Rim Kim,Eun Shil Kim,Jong Woong Park,Woong‑Gyo Jung,Hojeong Jeon,Yu‑Chan Kim,Hyun‑Kwang Seok,Jae Ho Shin,Myoung‑Ryul Ok 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.4
The excessive initial corrosion rate of Mg is a critical limitation in the clinical application of biodegradable Mg implantsbecause the device loses its fi xation strength before the fractured bone heals. This study suggests a new approach to overcomethis hurdle by accelerating tissue regeneration instead of delaying the implant biodegradation. As angiogenesis is anessential process in early bone regeneration, a Mg implant coated with electrospun nanofi bers containing nitric oxide (NO),which physiologically promotes angiogenesis, is designed. The integrated device enables adjustable amounts of NO to bestored on the NO donor-conjugated nanofi ber coating, stably delivered, and released to the fractured bone tissue near theimplanted sites. An in vitro corrosion test reveals no adverse eff ect of the released NO on the corrosion behavior of the Mgimplant. Simultaneously, the optimal concentration level of NO released from the implant signifi cantly enhances tube networkformation of human umbilical vein endothelial cells without any cytotoxicity problem. This indicates that angiogenesis canbe accelerated by combining NO-releasing nanofi bers with a Mg implant. With its proven feasibility, the proposed approachcould be a novel solution for the initial stability problem of biodegradable Mg implants, leading to successful bone fi xation.
ZnS : (Mn, Cu, Cl)과 (Zn, Cd)S:Cu, Cl 형광체의 Electroluminescence 에 관한 연구
신영진,유평렬 全北大學校 1986 論文集 Vol.28 No.-
A study has been made on the electroluminescence of zinc sulfide phosphors. The samples of ZnS : Mn, ZnS : Cu, Cl, ZnS : Mn, Cu, Cl and (Zn, Cd) S : Cu, Cl are prepared by firing zinc sulfide with appropriate impurites at 850℃ for an hour in nitrogen gas. The crystal structures of these phosphors are mixed phase of cubic and hexagonal. In the case of the (Zn, Cd) S : Cu, Cl phosphors, it seems that the radiative energy of the recombination between the donor Cl substituted for S and the acceptor Cu substituted for Zn or Cd is 1.88ev. It is also shown that the peaks at 580nm may be attributable to the transitions of Mn atoms from the first excited state ^4T_1(^4G) to the ground state ^6A_1(^6S) due to energy transfer. The intensity of electroluminescence increases with A.C. voltage(v) applied according to the formula In I∝-c/√v, where c is a constant.
창의성 관점에서 본 제 7차 초등 수학과 교육과정 : 규칙성과 함수를 중심으로 Focusing on Patterns and Functions
서경혜,유솔아,정진영 한국수학교육학회 2003 初等 數學敎育 Vol.7 No.1
The present study examined the 7th national elementary school mathematics curriculum from a perspective of mathematical creativity. The study investigated to what extent the activities in the Pattern and Function lessons in the national elementary school mathematics textbooks promoted the development of mathematical creativity. The results indicated that the current elementary school mathematics curriculum was limited in many ways to promote the development of mathematical creativity. Regarding the activities in Pattern lessons, for example, most activities presented closed tasks involving finding and extending patterns. The lesson provided little opportunities to explore the relationships among various patterns, apply patterns to different situations, or create ones own patterns. In regard to the Function lessons, the majority of activities were about computing the rate. This showed that the function was taught from an operational perspective, not a relational perspective. It was unlikely that students would develop the basic understanding of function through the activities involving the computing the rate. Further, the lessons had students use exclusively the numbers in representing the function. Students were provided little opportunities to use various representation methods involving pictures or graphs, explore the strengths and limitations of various representation methods, or to choose more effective representation methods in particular contexts. In conclusion, the lesson activities in the current elementary school mathematics textbooks were unlikely to promote the development of mathematical creativity.
Yu-Jin Jung(정유진),Yu-Yeong Park(박유영) 숭실대학교 영재교육연구소 2018 Global Creative Leader Vol.8 No.2
This research aims to examine the effects of unplugged early childhood software activity on the problem solving and scientific investigation skills of young children. The research subjects were 38 five-year-old children from two classes at the E child-care center in G city. Class A with 18 children was randomly selected as the experimental group and Class B with 20 children was selected as the comparison group. The unplugged software activity was carried out for 4 weeks from April 2nd 2018 to 4th May 2018. It was demonstrated that the children who used the unplugged early childhood software activity had significantly higher problem solving and science investigation skills. The result suggests that unplugged software activity can be a meaningful teaching method in classrooms. 본 연구는 언플러그드를 활용한 유아 소프트웨어 활동이 유아의 문제해결력과 과학적 탐구능력에 미치는 영향에 대해 알아보고자 하였다. 연구대상은 G광역시 E어린이집 만 5세 두 학급의 유아 38명을 선정하였으며, A학급 유아 18명을 실험집단으로, B학급 유아 20명을 비교집단으로 임의 배정하였다. 언플러그드를 활용한 유아 소프트웨어 활동은 2018년 4월 2일~5월 4일까지 4주에 걸쳐 실시하였다. 연구결과 언플러그드를 활용한 유아 소프트웨어 활동을 실시한 실험집단 유아의 문제해결력과 과학적 탐구능력이 통계적으로 유의미하게 높은 것으로 나타났다. 이러한 본 연구 결과는 언플러그드를 활용한 유아 소프트웨어 활동이 유아의 문제해결력과 과학적 탐구능력에 긍정적 영향을 주므로 유아교육현장에서 의미 있는 교수활동으로 활용될 수 있음을 시사한다.
Quantitative CT Measurements of Emphysema in Never Smoker COPD
( Yu Il Kim ),( Ji Sun Oh ),( Sun Min Kim ),( Hyun Wook Kang ),( Jin Yeong Yu ),( Bo Ram Lee ),( Woo Jin Kim ),( Hee Jung Ban ),( Yong Soo Kwon ),( In Jae Oh ),( Kyu Sik Kim ),( Young Chul Kim ),( Sun 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-
Introduction: Although cigarette smoke is the most important risk factor for COPD, never smokers also comprise important proportion of COPD. There is limited knowledge about CT quantitative measurement of emphysema in never smoker COPD. Objectives: To describe the differences of quantitative measurement of emphysema between never smoker and ever smoker COPD. Methods: We included patients with COPD who were older than 45 years. All subjects underwent spirometry and multi-dectector computed tomography examination. The MDCT images were analyzed to determine total emphysema (defined as the percentage of low attenuation areas [LAA%] less than -950 Hounsfield units; %LAA950). Differences between never and ever smokers were examined. Results: A total of 49 COPD patients were inclued; 23 never smokers and with 25 ever smokers The mean %LAA950 was 0.5 (SD, 1.1) and 15.3 (SD, 7.0) in never and ever smoker COPD cases, respectively. %LAA950 was significantly lower in never smokers with COPD compared to ever smokers (p<0.001). In the multivariate analysis adjusting age, sex and lung volumes, smoking status was the significant factor to determine the severity of emphysema. Conclusions: Never smokers with COPD have less CT emphysema than smokers. This difference in radiographic expression may in part explain the different features of COPD according to smoking status.
Rigid Bronchoscopy in Central Airway Obstructions
( Jin Yeong Yu ),( Hee Jung Ban ),( In Jae Oh ),( Kyu Sik Kim ),( Yu Il Kim ),( Sung Chul Lim ),( Young Chul Kim ),( Yong Soo Kwon ) 대한결핵 및 호흡기학회 2012 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.114 No.-
Objective: The aim of this study was to evaluate the usefulness of rigid bronchoscopy for alleviating central airway obstruction. Methods: Patients who had central airway obstructions and received a rigid bronchoscopy under general anesthesia from February 2008 to July 2012 at Chonnam National University Hospital were retrospectively reviewed. Results: Among 29 subjects, female patients comprised 62.1% (n=18), and median age was 63 (interquartile range [IQR] 53-69). The causes of airway obstruction include malignancy (n=14) and benign (n=15). Of the 15 benign lesions, 7 were benign tumors and 8 were benign strictures. In 13 cases of malignant airway obstruction, lung cancer was main cause (n=5). According to types of central airway obstruction caused by tumors, 8 were intraluminal, 3 were extraluminal, and 9 were mixed type. Most cases were located in trachea (n=20) and median degree of stenosis was 90% (IQR 88-95). Concerning about procedures, APC was applied in 16 cases, bougienation using with rigid bronchoscopy was applied in 16 cases, and silicone stent insertion was performed in 6 cases. All patients except 3 who had no dyspnea before procedure showed improvement in dyspnea and 9 of 10 who performed pulmonary function tests before and after bronchoscopy showed improvement in FEV1 (53 [IQR 37-68] vs 94 [IQR 83-110], % predicted, p=<0.001 ). There were no procedure related acute complications and mortality. Conclusions: Rigid bronchoscopy was an effective and safe procedure to alleviate central airway obstructions.