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Yeong Ju Yu,Jeong Hee Yu,Jin Hur 한국예방수의학회 2023 예방수의학회지 Vol.47 No.4
The optimization of a prevention program utilizing a novel trivalent inactivated Salmonella bacterial vaccine to protect poultry from Salmonella infections was evaluated in this study. A total of 50 brown nick layers were divided into 5 groups, A to E, each containing 10 hens. Group B hens were immunized with the SG9R vaccine, group C chickens were immunized with the trivalent inactivated Salmonella bacterial vaccine, and group D hens were primed with SG9R and boosted with the trivalent inactivated Salmonella bacterial vaccine. Group E hens were injected with sterile PBS. All hens in groups B to E were orally challenged with a mixture of wild-type S. Enteritidis, S. Typhimurium, and S. Gallinarum (approximately 6×10⁹ CFU/ 0.2 ml/bird). Serum IgG titers, CD3+CD4+ T-cell levels, and CD3+CD8+ T-cell levels in group D were significantly higher than those in group A. Additionally, all animals in groups A to D showed no clinical symptoms and survived after the virulent challenges, whereas all chickens in group E died following the challenge. The challenge strains of S. Enteritidis, S. Typhimurium, and S. Gallinarum were not isolated from the liver, spleen, cecum, and cloaca of group D chickens. These findings indicate that priming with SG9R and boosting with a trivalent inactivated Salmonella bacterial vaccine can be an effective approach for preventing Salmonella infections by inducing robust protective humoral and cellular immune responses in chickens.
McIndoe 수술법으로 질 성형술을 시행한 뮬러관 결손증 2 예
유동주 ( Yu Dong Ju ),박철홍 ( Park Cheol Hong ),김혁 ( Kim Hyeog ),신소영 ( Sin So Yeong ),최은영 ( Choe Eun Yeong ),홍서유 ( Hong Seo Yu ),이진용 ( Lee Jin Yong ) 대한산부인과학회 2004 Obstetrics & Gynecology Science Vol.47 No.2
Vaginal agenesis is uncommon gynecologic condition, and the most common etiology is Mu¨llerian agenesis also called Mayer-Rokitansky-Kster-Hauser (MRKH) syndrome. In such patients, the evaluation for associated malformations as well as careful non-surgical and surgical approach are essential. The neovaginoplasty is an important issue for these patients from a functional and a psychological standpoint. We describe two patients with Mu¨llerian agenesis, who have undergone vaginal reconstruction by McIndoe technique.
김유진 ( Yu Jin Kim ),백소영 ( So Yeong Baek ),안세연 ( Se Yeon An ),이미희 ( Mi Hui Lee ),이선영 ( Seon Yeong Lee ),이연주 ( Yeon Ju Lee ),이유리 ( Yu Ri Lee ),인미희 ( Mi Hui In ),한다은 ( Da Eun Han ),최준선 ( Jun Seon Choi ) 한국치위생학회 2012 한국치위생학회지 Vol.12 No.5
Objectives: The purpose of this study was to investigate the factors related to the awareness level of community water fluoridation program. Methods: 700 subjects were surveyed among the residents living in Incheon Metropolitan City. Data were collected on awareness of community water fluoridation program, general factors, oral health behavior, self-reported oral health and oral health interest. The factors related to the awareness level of community water fluoridation program were analyzed by t-test, a one way ANOVA and multiple linear regression analysis. Results: 1. Subjects` ages were 40~59 years, monthly average incomes were more than 3 million won and higher their educational levels had a higher awareness level of community water fluoridation program(p<0.01). 2. People who brushed their teeth more than three times a day, used oral hygiene devices, and had periodic oral examination and removed plaques were had higher awareness level of community water fluoridation program(p<0.01). Especially, the use of oral hygiene devices was the strongest factor in relation with the awareness level of community water fluoridation program(p<0.01). 3. People who had a fine self-reported oral health, highly interested in dental hygiene and made an effort to keep oral health were had higher awareness level of community water fluoridation program(p<0.001). Conclusions: The awareness level of community water fluoridation program was related to oral health behavior, self-reported oral health and oral health interest. So, in order to expand the areas for community water fluoridation program, it is important to educate to the right information about objectives, safety, dental caries preventing effect of the community water fluoridation program. And the education and publicity on general oral health will have an affirmative effect on expanding community water fluoridation program.
Cisplatin의 세포독성에 대한 레몬밤 추출물의 억제 효과
최유선 ( Yu Sun Choi ),김선주 ( Sun Ju Kim ),유영월 ( Yeong Wol Yu ),임요섭 ( Yo Sup Rim ),황은희 ( Eun Hee Hwang ),이화정 ( Hwa Jeong Lee ),최은영 ( Eun Young Choi ),장병수 ( Byung Soo Chang ),정인주 ( In Ju Jung ) 대한미용학회(구 대한미용과학회) 2013 대한미용학회지 Vol.9 No.1
The purpose of this study is to evaluate the protective effect of Lemon balm (Mellisa officinalis) extract on the cytotoxicity induced by cisplatin, pharmaceutic alopecia inducer. To achieve this, cisplatin-induced cytotoxicity was assessed by XTT assay after human skin fibroblasts (Detroit 551) were cultured in media containing various concentrations of cisplatin. And also, the effect of vitamin E was examined on the cisplatin-induced cytotoxicity. For the protective effect of Lemon balm extract on cisplatin-induced cytotoxicity, Detroit 551 cells were pretreated with 80 or 100 μg/mL of Lemon balm extract for 2 hours, and also, antioxidative effects of Lemon balm extract such as 1,1-diphenyl-2-picrylhydrazyl (DPPH)-radical scavenging activity and lactate dehydrogenase (LDH) activity were analysed. The results were as follows. Cisplatin showed a significant decrease of cell viability in dose dependently, and the XTT50 value was calculated at 25.7 μM. In the effect of vitamin E, it significantly increased cell viability which were decreased by the cisplatin-induced cytotoxicity. In the protective effect of Lemon balm extract on cisplatin-induced cytotoxicity, it significantly increased cell viability which was decreased by cisplatin-induced cytotoxicity, and also it showed the DPPH-radical scavenging activity and LDH inhibitory activity. Therefore, these results suggested that the cytotoxicity of cisplatin may be involved in oxidative stress, and also, Lemon balm extract effectively prevented the cytotoxicity induced by cisplatin via antioxidative effect. Conclusively, the natural extract like Lemon balm may be useful for the development as antioxidative agent via the prevention of the cytotoxicity induced by pharmaceutic alopesia inducer correlated with oxidative stress.
농업용드론 활용 벼 항공직파 시 파종기 살포형태에 따른 생육 특성
강영호 ( Yeong-ho Kang ),유영석 ( Yeong-seok Yu ),김효진 ( Hyo-jin Kim ),최유나 ( You-na Choi ),조대호 ( Dae-ho Jo ),유승화 ( Seung-hwa Yu ),이춘구 ( Chun-gu Lee ),김주 ( Ju Kim ) 한국농업기계학회 2022 한국농업기계학회 학술발표논문집 Vol.27 No.2
우리나라는 현재 농촌인구의 지속적인 감소와 고령화 등으로 농업 생산에 많은 문제점이 발생하고 있다. 특히 노동력 부족은 농업중심의 지방자치단체에서 극복해야 하는 최대 숙제가 되고 있다. 이에 최근 고도화된 디지털기술 기반의 드론, 센서, 로봇 등을 활용한 효율적인 농업이 빠르게 확산되고 있다. 본 연구는 벼 재배시 육묘·이앙 작업 등 노동력 절감하기 위한 드론을 활용한 벼 항공직파 시 파종기의 살포형태에 따른 벼의 생육특성을 조사하였다. 본 시험은 김제시 광활면의 간척지 벼 재배포장에서 수행하였다. 시험품종은 예찬벼(천립중:26.8g)를 활용하여 22년 5월 19일에 파종량 4kg/10a 수준으로 파종하였다. 파종시 8엽기(21inch) 농업용드론에 원판회전식 입제살포기와 농촌진흥청에서 개발 중인 직분사식 파종기를 각각 부착하여 5m/s 내외의 비행속도, 2.5m 살포고도(유효살포폭: 3~5m), 살포기 개폐율 70~100%의 살포조건으로 진행하였다. 시비, 병해충 방제 등 기타 재배는 농촌진흥청 벼 표준재배법에 준하였다. 파종량에 따른 ㎡ 당 입모수는 직분사식 정밀파종기가 원판회전식 입제살포기 대비 평균 13.7개 많은 것으로 조사되었다. 파종된 종자의 분포정도를 조사한 결과 원판회전식 형태는 좌측으로 종자가 편중된 경향을 보였으며 직분사식 형태은 비교적 균일하게 파종되었다. 변이계수 분석결과 직분사식 파종기가 원판회전식 입제살포기 대비 7% 이상 향상된 것으로 나타났다. 벼 출수기는 8월 19일로 동일하였으며 ㎡당 수수는 390-420개로 조사되었다. 수확 후 수량 및 수량구성요소, 품질 등에 대한 조사를 진행할 예정이다. 직분사식 파종기의 단위시간당 작업량, 정밀도 등 농작업 효율 등을 개선하고 벼 항공직파에 대한 매뉴얼을 정립한다면 대규모 간척지 또는 들녘 등 실용화가 가능 할 것으로 판단된다.