경연 대회를 통한 초ㆍ중고생의 창의력 신장 효과에 관한 연구

이희복,육근철,류해일,김현섭,김희수,박달원,유병환,김선효,김여상,서광수,변두원,서명석,배성효,박종석,심규철,이성희 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1

미래 사회를 대비하기 위한 개인의 개성을 존중과 창의적인 능력을 지닌 인간을 양성을 목적으로 충청남도 지역의 초 ㆍ 중고등학생들을 대상으로 한 창의력 경연대회가 공주대학교 과학교육연구소에서 개최되었다. 충청남도 초 ㆍ중 ㆍ 고등학생들을 대상으로 실시한 창의력 경연대회는 창조적 아이디어를 내어 스스로 문제를 해결해 나갈 수 있는 교육 프로그램을 제공하는 좋은 기회였음이 확인되었으나, 일부의 팀에서만 참신하고 재미있는 아이디어들이 제안되었다. 여학생의 참가자 수가 상당히 증가하였으며, 대체적으로 입상권의 학생들의 상당 부분이 여학생이라는 것이 특이할만하다. 학년이 올라감에 따라서 창의적인 아이디어를 내는 양이나 질에 있어서 뒤떨어지는 것으로 분석되었으며, 토론 학습의 적응력이 미흡하고 발표력 및 청취력에 있어서도 떨어지는 것으로 나타났다. 따라서 중 ㆍ고등학교의 학교교육에서도 학생들에게 프로젝트형 탐구학습 프로그램의 적용은 물론 토론식 수습을 통한 학생들의 사고의 전환의 기회를 제공해야 할 것으로 사료된다. The creativity competition was held to foster the creativity of elementary and secondary school students in the Institute of Science Education, Kongju national University. It was found that the creativity competition effected on the improvement of inventing creative ideas and problem solving activities. But, only some competitors participated in semifinal and final contests, presented original and interesting ideas. More female students participated in competition than last year. More female participants were awarded a prize than males. Totally, participants were defective in discussion and communication, and presentation and listening ideas. Increasing grades correlated inversely with creativity and originality. There is need of inquiry project teaming programs and presenting opportunities of conversion of thinking by discussing instructions in school

한국 제조기업의 공급자 관계유형에 대한 연구

김종래,박해천 조선대학교 생산기술연구소 2003 生産技術硏究 Vol.25 No.1

The purpose of this study is to empirically examine the types of supplier relationships of Korean manufacturing companies. This analysis is divided into three steps, (1) finding major factors of supplier relationships, (2) clustering similar groups in supplier relationships, (3) examining the characteristics of the groups The result of the analysis is as follows First, by the factor analysis, four factors are found - information & technology assistance, finance assistance, payment, communication. Second, by the cluster analysis with four factors, three groups are generated Three groups consist of traditional supplier relationships, semi-supportive supplier relationships, supportive supplier relationships The difference of group of semi-supportive supplier relationships and supportive supplier relationships is the factor of finance assistance. Third, by the statistical analysis, it is verified that supportive group recognizes the risk of external environment more highly, and is more delivery performance oriented. And the correlation between groups and types of manufacturing systems were found.

침적형 고정생물막 반응기에서 유기물질 및 질소제거 특성 비교

김영오,남해욱,이종현,박태주 부산대학교 환경문제연구소 1999 環境硏究報 Vol.17 No.1

The two processes of R-1 process(anaerobic/anoxic/aerobic reactor) and R-2 process(anoxic/aerobic reactor) were investigated into the operating strategy of the four kinds of HRTs(4, 6, 8, and 10hr) using the raw sewage in Janglim WWTP The sewage contained various refractory wastewaters such as, leachate, industrial wastewater, pigment wastewater. The purpose of this study was find out to the optimal process that was enhanced to remove not only organic compounds, but also nitrogen and phosphorus, when the influent was used to the refractory sewage. As the range of COD^cr, loading rate during operating days was from 0.66kg/m^3/day to 1.63kg/m^3/day, the effluent concentration was 52.0 ~77.0mg/L in R-1 process and 59.0~81 0mg/L in R-2 process, respectively. Increasing the NH_4^+-N loading rate from 126.5g/m^3/day to 326.3g/m^3/day, the removed loading rates were 116.5~196.4g/m^3/day of R-1 process, and 117.7~191.6g/m^3/day of R-2 process, respectively. The removals of organics and NH_4^+-N of R-1 process were slightly higher than those of R-2 process, but the differences were almost negligible. The phosphorus removal efficiency was 50. 5~34.0% of R-1 process and 40.5 ~25.5% of R-2 process, respectively. The difference of the phosphorus removal efficiency was considered because of the effect of phosphorus release in anaerobic reactor and phosphorus uptake in aerobic reactor by facultative bacteria as well as higher COD_cr,/TP ratio in anoxic reactor of R-1 process by 40% by-pass. Hence, the results of this study showed that R-1 process with by-pass was more suitable for nutrient treatment than R-2 process. The submerged fixed-biofilm packed with SAC media could be applicable for the refractory wastewater treatment.

C₄H_9O_6N(Ammonium Hydrogen D-Tartrate)의결정 구조

김문집,박해윤,박호종 순천향대학교 기초과학연구소 2001 순천향자연과학연구 논문집 Vol.7 No.1

The structure of Ammonium Hydrogen D-Tartrate(C4H9O6N) has been determined by X-ray diffraction methods. The crystals are Orthorhombic, space group P212121, unit cell constants, a=7.6431(7)Å, b=7.8418(5)Å, c= 11.0605(11)Å, α= β= γ=90˚, V=662.92(10)Å3, T= 296(2)K, Z=4, Dc= 1.6744Mgm-3. The intensity data were collected on an Enarf-Noius CAD-4 Diffractometer with graphite monochromated Mo Kα radiation. The molecular structure was solved by direct method and refined by full-matrix least squares to a final R = 3.18% for 682 unique observed F0>4σ(F0) reflections and 137 parameters. The molecular have 8 intermolecular hydrogen bonds.

석유 화학 공장 폐수처리를 위한 고정생물막공법의 Pilot Plant 적용

이종현,남해욱,김미화,박태주 부산대학교 환경문제연구소 1998 環境硏究報 Vol.16 No.-

The pilot plant of biological fixed-film process(BFFP) was developed to treat the petrochemical wastewater with high organic loading rate, where a stationary biofilm was attached to net-type media(SARAN 1000D) under diffused aeration. The specific surface area of SARAN 1000D was 400 ㎡/㎥ approxirnately. The organic removal ability was tested in the pilot-scale three biological fixed-film reactors. The pilot scale reactor demonstrated more than 95% effciency in removing chemical oxygen demand(COD) at B reactor with 20% Packing ratio. The reactor also showed stable performance at the organic loading rates of 1.27~3.12 ㎏ COD/㎥/day. The effluent COD and SS concentrations of the pilot scale reactors were more unstable than those of the lab scale reactors. Based on the experimental results, the BFFP could be suitable for pre-treatment petrochemical wastewater with relatively high organic loading rate.

들깨의 수용성화합물질과 그들의 타감작용

金海洙,金鐘熙 慶南大學校 附設 基礎科學硏究所 2000 硏究論文集 Vol.14 No.-

생잎과 뿌리 수용추출물이 함유하고 있는 화합물질은 phenolic compounds가 주였고, 잎추출물은 17종 acids와 9종의 비acids화합물질, 뿌리추출물에서는 15종의 acids와 6종의 비acids가 검정 및 동정되었다. 잎과 뿌리의 수용 추출물은 선정된 수용체 식물의 발아를 억제하였으며, 추출액 농도가 높을수록 억제 효과도 컸다. 잎의 경우 발아억제 효과는 고추, 쇠무름, 달맞이꽃 순 이었고, 뿌리는 쇄무름, 달맞이꽃, 고추, 상추 순이었다. 잎 추출물 억제효과는 뿌리추출물 보다 상대적으로 높았다. 그러나 오이, 배추, 무는 잎과 뿌리추출물 모두에서 억제효과가 현저히 낮지는 않았다. 잎과 뿌리의 수용 추출물은 선정된 수용체 식물의 성장에 상당한 억제효과를 일으켰다. 수용추출의 농도증가에 따라 억제효과가 현저히 증가되었으며, 잎의 경우 억제효과가 상대적으로 낮았다. 억제 효과는 잎과 뿌리모두에서 고추, 달맞이, 쇠무름이 낮았으며, 오이에 대한 억제효과가 가장 낮았다. 또한 잎과 뿌리수용추출물의 발아 및 성장 억제효과에서 야생종 쇠무름, 달맞이꽃에서 총체적으로 억제효과가 경작종 보다 높음을 보여주었다. The main compounds in aqueous extract of P. frutescens leaves and roots were the phenolic compounds. 17 acids and 9 non-acids compounds in leaves, 15 acids, and 6 non acids compounds in roots were identified. Aqueous extract of P. frutescens leaf and root had an inhibition effect on the germination of selected receptor plant species. The inhibition effects were higher along with the concentration raising, and inhibition effect from leaf extracts was much higher than in the root extracts. The leaf-extract inhibition effects on Capsicum annuum linne. Achyrant japonica. Oenothera odorta leaf extracts, and root-extract inhibition effects on Achyrant japonica. Oenothera odorta, Capsicum annuum. Lactuca sativa were much higher than others. Aqueous extract of P. frutescens leaves and roots also had inhibition effects on the elongation of selected receptor-plant species. The inhibition effects were represented higher along with the concentration raising, and effects on Capsicum annuum. Achyrant japonica. Oenothera odorta were much higher than others.

들깨(Perilla frutescens) 잎과 줄기에서의 정유특성과 안정성

金海洙,金鐘熙 慶南大學校 附設 基礎科學硏究所 2000 硏究論文集 Vol.14 No.-

5개의 다른 장소에서 경작된 들깨를 대상으로 생잎과 줄기를 채취하여, Gas Chromatography Mass spectrometer(GC-MS)를 이용하여, 잎과 줄기에 함유된 정유의 조성과 함량을 분석하였다. 잎과 줄기의 정유의 조성은 매우 단순하였고(주요 성분은 8종류), 총함량은 건중의 1%정도였고, 그중 2-butanoyl furan 한 성분이 90%이상을 차지하였다. 줄기의 정유조성은 잎과 유사하나 함량은 잎의 1%정도에 불과하였다. 정유 총 함량은 계절에 따라 뚜렷한 차이가 있었고 7월이 가장 높았다. 각각 다른 온도에서 한시간 건조한 들깨잎은 여전히 30℃, 50℃에서는 약 90%, 80℃는 60%, 100℃ 40%이상의 정유를 함유하였고, 염수(salt solution)처리 6개월후의 들깨잎은 염농도와 관계없이 90%이상의 정유를 함유하고 있었다. The composition of essential oil in Perilla frutescens leaves and stems were identified and measured quantitatively by using Gas Chromatography and Mass Spetrometer (GC-MS). The total amount of essential oil in the leaf was much high, the highest total amount exhibited in July and varied with season, but the essential oil composition was much simple(the major composition was only eight kinds) and only 2-butanoyl furan composed over 90% of the total amount. The total amount in stem was very low and the composition also was very simple (only four kinds). After treatment with different temperature.(30℃, 50℃ 80℃ and 100℃), Perilla frutescens leaf still remained much of oil(at 30℃, 50℃ remained 90℃, 80℃ remained 60%, at 100℃ remained 40%) and after treatment with different concentration of salt solution (10%, 30%, 50% 80%)six months, it still remained over 90% of essential oil in fresh leaf.

중합효소연쇄반응을 이용한 도말양성 폐결핵 환자에서의 결핵균 DNA 검출방법에 관한 연구

이종진,김애경,조해정,한표성,홍석철,김주옥,김선영 충남대학교 의과대학 지역사회의학연구소 1994 충남의대잡지 Vol.21 No.2

Polymerase chain reaction (PCR) is the most sensitive and rapid method for the diagnosis of M.tuberculosis infection. Many reports have shown different methods for mycobacterial DNA extraction, but revealed many differences in simplicity and time-consumption. We studied which method was the best among 7 different ones for DNA extraction from 32 smear-positive sputa, using PCR of targeting 123bp DNA fragment of IS6110. The methods were the following : SDS-Microwave oven method, NaOH Lysis method, Triton X-100, Proteinase K method, Lysis buffer method. SDS-Proteinase K method, Bead Beater method, and Bead Beater/CTAB method. The amplification products were identified by electrophoresis on ethidium bromide-stained agarose gels, and confirmed by restriction enzyme, Southern blot hybridization, and DNA sequencing. All 32 cases were positive (100%) by the 7 different methods. It took 1 hour or more to detect DNA in SDS-Microwave oven method, NaOH Lysis method, and Bead beater/CTAB method. It took 2 hours or less in the others. SDS-Proteinase K method and Bead Beater/CTAB method were simpler and more convinient than the others. These results suggest that SDS-Proteinase K method and Bead Beater/CTAB method might be better than the others for the extraction of mycobacterial DNA in terms of simplicity and time-consumption, although all the methods were sensitive.

Development of Biodegradable Methoxy Poly(ethyleneglycol)-polyesters Diblock Copolymers as Drug Carrier for Implantable Disc

( Jong Tae Ko ),( Jae Ho Lee ),( Jong Min Kim ),( Moon Suk Kim ),( John M. Rhee ),( Hai Bang Lee ),( Gil Son Khang ) 한국조직공학과 재생의학회 2006 조직공학과 재생의학 Vol.3 No.2

The main objective of this study is to investigate the feasibility of methoxy polyethyleneglycol (mPEG) and poly(D,L-lactide-co-glycolide) (PLGA) or poly(ε-caprolactone) (PCL) diblock copolymers as implantable drug carriers. A series of diblock copolymers were synthesized by ring-opening polymerization with different molecular weight of mPEG. 1H-NMR, FT-IR, XRD and GPC were used to characterize the obtained various diblock copolymers. The fabricated dexamethasone-loaded discs were incubated at 37 oC in phosphate buffer saline (PBS, pH 7.4) and the effects of composition on the degradation rate of discs were examined by water absorption, mass loss, pH variation of in vitro media and composition changes using SEM, FT-IR, respectively. The in vitro rate of drug-loaded mPEG-PLGA, mPEG-PCL implantable discs depended on their composition, increasing when the mPEG molecular weight of diblock copolymers increased. Water absorption and mass loss of mPEG-PLGA copolymer discs as drug carrier seems to be more affected on mPEG molecular weight than mPEG-PCL copolymers. Also, the variation of pH of PBS as in vitro media was changed by cleavage of ester bond by hydrolysis. These results indicate that pH of PBS was faster decreased with increasing of mPEG molecular weight in the all copolymers. It can be expected that optimized copolymer composition and molecular weight may be providing further application as the implantable drug carrier for different drugs in controlled drug delivery system.

Memory Enhancing and Neuroprotective Effects of Selected Ginsenosides

Hai Ying Bao,Jing Zhang,여수정,Chang-Seon Myung,Hyang Mi Kim,Jong Moon Kim,박정일,조정숙,Jong Seong Kang 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.3

The effects of ginsenosides Rg3(R), Rg3(S) and Rg5/Rk1 (a mixture of Rg5 and Rk1, 1:1, w/w), which are components isolated from processed Panax ginseng C.A. Meyer (Araliaceae), on memory dysfunction were examined in mice using a passive avoidance test. The ginsenosides Rg3(R), Rg3(S) or Rg5/Rk1, when orally administered for 4 days, significantly ameliorated the memory impairment induced by the single oral administration of ethanol. The memory impairment induced by the intraperitoneal injection of scopolamine was also significantly recovered by ginsenosides Rg3(S) and Rg5/Rk1. Among the three ginsenosides tested in this study, Rg5/Rk1 enhanced the memory function of mice most effectively in both the ethanoland scopolamine-induced amnesia models. Moreover, the latency period of the Rg5/Rk1-treated mice was 1.2 times longer than that of the control (no amnesia) group in both models, implying that Rg5/Rk1 may also exert beneficial effects in the normal brain. We also evaluated the effects of these ginsenosides on the excitotoxic and oxidative stress-induced neuronal cell damage in primary cultured rat cortical cells. The excitotoxicity induced by glutamate or Nmethyl- D-aspartate (NMDA) was dramatically inhibited by the three ginsenosides. Rg3(S) and Rg5/Rk1 exhibited a more potent inhibition of excitotoxicity than did Rg3(R). In contrast, these ginsenosides were all ineffective against the H2O2- or xanthine/xanthine oxidase-induced oxidative neuronal damage. Taken together, these results indicate that ginsenosides Rg3(S) and Rg5/Rk1 significantly reversed the memory dysfunction induced by ethanol or scopolamine, and their neuroprotective actions against excitotoxicity may be attributed to their memory enhancing effects.