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김종래,이석하,오흥근,진양화 대한마취과학회 1972 Korean Journal of Anesthesiology Vol.5 No.1
Brachial plexus block has been evaluated in 192 cases of surgery of the upper extremities performed during the past 13 years and 9 months. (from Jan. 1958 to Sept. 1971) We have assessed supraclavicular and axillary brachial plexus block using 1% to 2% procaine and lidocaine adding adrenaline case by case. The dosage given was 30 ml to 40 ml in each case There were 142 males and 50 females. In 26 blocks judged unsatisfactory for surgery, we have usually substituted inhalation anesthesia and .2 cases were supplimented with intravenous thiopental sodium, 2.5%, 3 ml to 5 ml intermittently and 4 cases with intravenous thiopental sodium and meperidine. There were 4 cases of complications of supraclavicular brachial plexus block including 2 cases of pneumothorax, one of Horners syndrome only and a cardiac arrest immediately after block. There were no complications in axillary approaches. Therefore in conclusion this brachial plexus block was a simple and useful technic in surgery and treatment of the upper extremities.
Neostigmine 분할투여가 Vecuronium 차단 가역에 미치는 영향
김종래,김진수,이영석 대한마취과학회 1990 Korean Journal of Anesthesiology Vol.23 No.1
The hypothesis that administration of neostigmine in divided doses might accelerate the antagonism of nuromuscular blockade was investigated. Neostigmine 0.05mg/kg was adminsitered either in a single bolus dose (Group I, n=10) or in an initial dose of 0.01 mg/kg 1 minute later (Group II, n=10), 2 minutes later (Group III, n=10) and 3 minutes later (Group IV, n=10) for antagonism of vecuronium- induced blockade. Reversal was attepted at 10 percent spontaneous recovery of twitch height. The mean time (±SE) from the first injection of the drug until the train-of-four(TOF) ratio value had reached 0.75 was signifincantly longer in Group II and IV (594.8±63.9 seconds and 555.6±22.2 seconds respectively) than Group I and III (380.6+36.0 seconds and 357.8±44.2 seconds respectively). It is concluded that adminstration of neostigmine in divided doses with 0. 01 mg/kg and 0.04 mg/kg did not produce a significantly faster reversal of residual vecuronium-induced neuromuscular blockade as compared to a single bolus adstration.
김종래,길혜금,강원경 대한마취과학회 1991 Korean Journal of Anesthesiology Vol.24 No.5
A 43 years old female patient who had known FSH form(Fascioscapulohumoral type) muscular dystrophy was scheduled for total abdominal hysterectomy due to uterine myoma. Induction of ansthesia was performed without muscle relaxant and maintained with fentanyl, oxygen and nitrous oxide. Muscle relaxation was excellent without neuromuscular blocking agent by the meuromuscular twitch monitoring(too week response to neuromuscular twitch at 70mA). After the end of operation, the patient was awaken without any problem and was transferred to recovery room.
Reactive Orange 16 Dye를 이용한 청색광차단 기능의 하이드로겔 콘택트렌즈 제조
김종래 대한시과학회 2022 대한시과학회지 Vol.24 No.4
Purpose : Blue-light blocking dyes were chemically conjugated to the hydrogel contact lenses. Blue-light blocking properties of the resultant contact were investigated, and the amounts of attached dyes were quantified. Methods : Vinyl sulfone-based Reactive Orange 16 Dyes were covalently conjugated to hydrogel contact lenses containing a considerable amount of alcohol groups. The investigation for blue-light blocking properties of the hydrogel lenses and the quantification for the amounts of attached dyes were performed using UV-vis spectrophotometer. Results : The blue-light blocking Reactive Orange 16 Dyes were successfully conjugated to the hydrogel contact lenses. The resultant contact lenses exhibited good blue-light blocking properties according to the results of the UV-vis spectra investigation. Reactive Orange 16 Dye conjugated to contact lenses was quantified using Beer-Lambert's law, and the blue-light blocking rate of contact lenses could be controlled by adjusting the concentration of reactive dye. Conclusion : In this study, a reactive dye with a blue-light blocking function was fixed to hydrogel contact lenses through chemical bonding, and their blue-light blocking function was analyzed. It was confirmed that as the concentration of the blue-light blocking dye increased in the chemical reaction, the blocking intensity in the blue light wavelength region between 380 and 500 nm and the amount of the conjugated dye also increased. The development of blue-light blocking contact lenses that can be mass-produced is expected to play an important role in the development of functional ophthalmic optical medical devices. 목적 : 반응성 청색광차단 염료를 하이드로겔 콘택트렌즈에 화학적으로 고정시켰고, 제조된 콘택트렌즈의 청색광차단 기능의 분석 및 첨가된 염료를 정량하고자 한다. 방법 : Vinyl sulfone-기반의 반응성 염료인 Reactive Orange 16 Dye를 다량의 알콜 작용기를 함유하는 하이드로겔 콘택트렌즈에 화학적으로 결합시켰다. 콘택트렌즈의 청색광차단 특성 및 염료의 정량은 UV-vis spectrophotometer를 이용하여 확인하였다. 결과 : 청색광차단기능의 Reactive Orange 16 Dye가 성공적으로 하이드로겔 콘택트렌즈에 결합되었다. UV-vis spectra 분석을 통해 염료를 함유한 콘택트렌즈들이 우수한 청색광차단 기능을 보임을 확인하였다. Beer-Lambert의 법칙을 이용하여, 콘택트렌즈에 첨가된 Reactive Orange 16 Dye를 정량하였으며, 반응 염료의 농도 조절을 통해, 콘택트렌즈의 청색광차단율을 조절할 수 있었다. 결론 : 본 연구에서는 청색광차단 기능의 반응성 염료를 하이드로겔 콘택트렌즈에 화학적 결합을 통해 고정시키고, 청색광차단 기능을 분석하였다. 화학적 반응에서 청색광차단 염료의 농도가 증가할수록, 380~500 nm 사이의 청색광 파장 영역에서의 차단 세기와 첨가된 염료의 양이 같이 증가함을 확인하였다. 대량생산이 가능한 청색광차단 콘택트렌즈의 개발은 기능성 안광학의료기기 개발에 큰 역할을 할 것으로 기대된다.
후쿠시마 측위하의 미세 혈관 감압술후 발생한 상기도 폐쇄와 상완 신경총 손상
김종래,민경태,강정완,박병학 대한마취과학회 1996 Korean Journal of Anesthesiology Vol.30 No.1
A 25 years old woman was adrnitted to the department of neurosurgery for a right hemifacial spasm. She was undertaken microvascular decompression in the Fukushima lateral position. Following completion of operation, she began to complain of dyspnea, but the phonation was not changed. Mild weakness and paresthesia on left upper extremity was complained, too. Severe swelling on the left side of face and neck expending to left shoulder was noted simultaneously. Immediate computerized tomography was taken to reveal the cause of respiratory distress, which suggested that venous and/or lymphatic congestion on the left side of neck. As respiratory distress was getting more severe, emergent tracheostomy was taken. The cause of above symptoms was suspected to an extreme rotation and flexion of the head resulting in direct contact of mandibular body to clavicle. A month after operation, there was still remained mild paresthesia on left thumb and index finger.s
김종래,박정현,이춘수,한영미,홍용우 대한마취과학회 1994 Korean Journal of Anesthesiology Vol.27 No.6
Most patients, who will undergo risky surgical operations such as cardiac surgery or lung surgery, may have some knowledge on the surgical or anesthetic procedure involved in the operations. In order to understand the actual degree of patients' knowledge regarding anesthesia and to make anesthetic information available to the public more effectively based on this understanding, a questionnaire survey was conducted to 154 patients who had operations at the Yonsei cardiac center between June 1992 and January 1993. The questionnaire was composed of 21 questions; 19 multiple-choices and 2 askings for simple descriptive answers. The survey results analyzed by sex, age, education and occupation. The Chi-Square analysis is conducted to test the statistical significance among different groups in each category. The survey shows that first, most patients wanted to get anesthetic information at the practical common sense through mass media. Thus it is necessary to continuously provide detailed anesthetic information to the public through mass media. Obviously, it is more effective to provide anesthetic information to the public or patients adjusted to their educational level. Secondly, patients wanted to consult anesthesiologist about their own anesthesia before operations, and the informative preoperative visit by anesthesiologist have positive psychological effect to patients. Therefore, it is desirable for an anesthesiologist to give preoperative visit to a patient explaining complexities which may occur during and after anesthesia.