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조정숙,안혜영,안숙희,이명수,허명행 한국여성건강간호학회 2012 여성건강간호학회지 Vol.18 No.2
Breast, Massage, Pain, Hydrogen‐ion concentration
비위관을 통한 유동식 투여방법이 소화기계에 미치는 영향
조정숙 병원간호사회 1996 임상간호연구 Vol.2 No.-
Some nasogastric tube feeding methods, which provide not only the physiological benefits for maintaining the enteral feeding but also the economical benefits and conveniences in feeding, has been required for critically ill patients. This paper is an empirical research which examines the differences in complications such as defecation pattern, gastric residual volume, and vomiting by the continuous infusion method and the Bolus method. Between the two nasogastric tube feeding methods, the higher frequencies of defecation, diarrhea, gastric residual volume and vomiting are shown in Bolus method, but no significant differences across methods are found for the patterns of gastric residual. In case of nasogastric tube feeding methods, the overall incidence of diarrhea shown in this paper (5.8%) is lower than the result of Cataldi and Betcher (1983), which reports the figure of 12~15% even for patients with normal gastrointestinal function, but the incidence is higher in the group using the Bolus method.
일차 배양한 흰쥐 대뇌피질세포의 흥분성 및 산화적 신경세포손상에 대한 소전재조환의 억제효과
조정숙 대한약학회 2003 약학회지 Vol.47 No.6
Xiaoshuan Zaizao Wan (XZW) has been used in China to improve hemiplegia, deviation of eye and mouth, and dysphasia due to cerebral thrombosis. To characterize pharmacological actions of XZW, we evaluated its effects on neuronal cell damage induced in primary cultured rat cortical cells by various oxidative insults, glutamate or N-methyl-D-aspartate (NMDA), and $\beta$-amyloid fragment ($A_{\beta(25-35)}$). XZW was found to inhibit the oxidative neuronal damage induced by $H_2O_2$, xanthine/xanthine oxidase, or $Fe^{2+}$/ascorbic acid. It also attenuated the excitotoxic damage induced by glutamate or NMDA. The NMDA-induced neurotoxicity was more effectively inhibited than the glutamate-induced toxicity. In addition, we found that XZW protected neurons against the $A_{\beta(25-35)}$-induced toxicity. Moreover; XZW exhibited dramatic inhibition of lipid peroxidation in rat brain homogenates and mild 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity. Taken together; these results demonstrate that XZW exerts neuroprotective effects against oxidative, excitotoxic, or $A_{\beta(25-35)}$-induced neuronal damage. These findings may provide pharmacological basis for its clinical usage treating the sequelae caused by cerebral thrombosis. Furthermore, XZW may exert beneficial effects on Alzheimer's disease and other oxidative stress-related neurodegenerative disorders.
조정숙,김관선,김우갑,Cho, Jeong-Sook,Kim, Kwan-Seon,Kim, Woo-Kap 한국현미경학회 1991 Applied microscopy Vol.21 No.2
Ventral nephrocytes in the larva of the Lucilia illustris comprise ellipsoid cells situated onto the salivary glands. The cells are $60{\sim}100{\mu}m$ in diameter. Junctional complex beneath the basement membrane hold the plasma membrane in a even contour. Intracellular channels from the juntion complex are well developed at the cortex part of the cell. Coated vesicles pinched off from the channels seems to be connected with the ${\alpha}$-vacuoles via the tubular elements, which is regared as selective absorption system from the hemolymph. Two nuclei are sometimes observed in the medulla part of the cell. Ventral nephrocytes contain well-developed rough endoplasmic reticulum and Golgi complex, and numerous mitochondria. These cellular organelles synthesize lysosome. The lysosome not only digest some cell organells but also seems to be related with the ${\beta}$-vacuoles.