혈액 내 구리, 아연 및 ceruloplasmin 농도에 흡연, 음주 및 신체적 활동이 미치는 영향

홍연표,강은용,신인철,최병선,박정덕,장임원,박진완 大韓産業醫學會 1999 대한직업환경의학회지 Vol.11 No.4

Objectives : To investigate the influence of smoking, alcohol ingestion, and physical activity on copper and zinc in RBC and serum and serum ceruloplasmin, this study was performed in a cross-sectional study in 113 healthy men aged 20 to 40 years who had no symptomatic liver, heart, gastrointestinal, and other chronic diseases. Methods : At the men's entry into the study, blood samples were drawn from each subject and immediately centrifuged for analysis of copper, zinc, iron, ceruloplasmin, total cholesterol, and hematocrit. Each man completed a questionnaire that provided information on smoking, amount of alcohol intake, and physical activity. Partial regression analysis was performed on confounding variables such as age, body mass index, hematocrit, serum cholesterol, and serum iron. Results : In general linear models, adjustment for confounding variables did not show statistical differences, and there was only an increasing tendency in serum copper in heavy smoker(P=0.0678). There was no difference between high physical activity with mild smokers and lower physical with heavy smokers. Conclusions : This study suggested that copper, zinc and ceruloplasmin were not good biomarker for early effect by smoking, alcohol intake and physical activity in young adult. However, selection bias should be considered in evaluation of this result, and a large prospective study will be needed in advance on usefulness of copper, zinc and ceruloplasmin as a marker for risk factors and early change of atherosclerosis.

임베디드 시스템에서 Mobile IP 프로토콜 구현

宋東勳,裵振勝,鄭燦赫,吳世德,李基源,劉忠烈,河載承,李光培,金玄郁 명지대학교 산업기술연구소 2005 産業技術硏究所論文集 Vol.24 No.-

With rapid growth of the internet, need for the mobile communication networks is increasing. In this paper, we implement and test Mobile IP Protocol in Embedded System. Our Mobile IP-based testbed consisted of two sub-networks and each sub-network was configured to operate independently through use of router. To satisfy integrated wired/wireless network model established on the testbed design and show generality of the testbed, we implemented mobile nodes, home agent, foreign agent and router on the basis of Linux operating system. As the results of the evaluation, we confirmed that mobile nodes operated properly according to Mobile IP Protocol.

SrTiO₃첨가에 따른 (x)BaTiO₃-(1-x)SrTiO₃의 유전적, 전기적 특성

정해덕,장동환,김덕근,홍경진,최창주 木浦大學校 工業技術硏究所 1998 工業技術硏究誌 Vol.8 No.-

In this paper, a ferroelectric material BaTiO3 was added to SrTiO3, then (x)BaTiO3-(1-x)SrTiO3(0.7≤x≤1) ceramics were fabricated with stable electrical properties in high voltage. Microstructures and electrical properties were investigated according to mixing conditions of addition material SrTiO3. As a result of the investigation of all experiments, the shrinkage was excellent in 0.9BaTioO3-0.1SrTiO3. The grain size was increased, the curie temperature was shifted low temperature. The 0.9BaTiO3-0.1SrTiO3 was appeared stable property in temperature vs. permittivity. Also, 0.9BaTiO3-0.1SrTiO3 was showed stable dielectric properties at 25~85[C]. V-I properties of specimen were observed in the temperature range of 21~143[C], were divided into three regions. the region I below 10[kV/cm] was shown Ohmic conduction, the region II from 10 to 30[kV/cm] was explained by the poole-Frenkel emission theory and the region III above 30[kV/cm] was analysed by the tunneling effect.

파괴역학에 근거한 철근콘크리트 보의 휨 파괴거동

어석홍,이형진,최덕진 국립7개대학공동논문집간행위원회 2002 공업기술연구 Vol.2 No.-

An analytical fracture mechanics approach was used to investigate the fracture behavior of reinforced concrete beams. By use of this approach based on fracture mechanics concepts, the crack width and length as well as the strength and cracking stability of reinforced concrete beams were investigated. The results obtained from the analytical studies were also discussed in terms of the minimum reinforcement ratio and crack width specified in design code provisions. The analytical approach based on fracture mechanics concepts are very useful to predict the fracture behavior of reinforced concrete beams.

젖소 足皮膚炎에 대한 오존수의 治療 效果

이수진,조성환,전무형,김덕환,박창식,한홍율,김명철 충남대학교 형질전환복제돼지연구센터 2007 논문집 Vol. No.10

This study was carried out to determine therapeutic the effect of ozonated water therapy on bovine pododermatitis. In addition, bactericidal effect of ozonated water on etiological agent of bovine pododermatitis was examined. The pathohistological examination for the pododermatitis, according to application with ozonated water and ozone ointment was investigated. Thirty healthy cattle were divided two groups(each of 15) : control group (povidone group), treatment group (ozone solution group). Various parameters were evaluated in terms of the lameness score, swelling score, lesion score, WBC count, neutrophil count, pathohistological finding, and antimicrobial action. The decrease of lameness and lesion score were shown in hoof lesions on 14 days after application of ozonated water. Significant decrease of swelling was shown in hoof lesions on 14 days 1 Corresponding author after application of ozonated water(p < 0.01). In hematological findings, WBC count revealed values within normal range. The number of neutrophils was slightly higher than that of normal, however, this was improved on 14 days after application of ozonated water. In pathohistological findings, recovery was rapid macroscopically and microscopically in the treatment with ozonated water on the hoof lesions and ozonated water was effective. In antimicobial action, bactericidal effect was observed in treatment with ozonated water on the hoof lesions and ozonated water was effective.

In Vivo ^31P NMR Spectroscopy를 이용하여 젖산 운동시간과 유산소 운동시간에 따른 골격근 섬유의 고 에너지 인(P) 대사 변화

성기홍,임태환,이대근,문치웅,이정희,김상태,신명진,이덕분 대한스포츠의학회 1994 대한스포츠의학회지 Vol.12 No.1

Intracellular high energy phosphorus metabolism can be assessed noninvasively and dynamically by in vivo ^31P NMRS of skeletal muscle have shown various applications of this technique in evaluating the pathophysiology of diseased or normal muscles. High energy phosphate metavolsim in the human skeletal muscle was studies in the work. ^31P nuclear magnetic resonance spectroscopy allowed the evaluate of the lactic acid and aerobic energy system in the intracellular skeletal muscle by energy concentration of ^31P nuclear magnetic resonance spectroscopy allowed the evaluate of the lactic acid and aerobic energy system in the intracellular skeletal muscle by energy concentration of ^31P metabolite, (Pi), (PCr), (ATP). The ratio of Pi/PCr the spectra measured from normal volanteers and elite athleties indicated a signetifcant difference between the two group for each exercise protocal. It was generally ovserved that the all out time of normal volunteers in shorter that that of elite athletes, and the ration of Pi/PCr is samller for elite athlets than for normal volunteers.

동물원에서 사육중인 Japanese Macaque (Macaca fuscata)에서 Zoletil 마취에 관한 연구

이재일,이수진,홍성혁,신남식,김덕환,박창식,전무형,조종민,김영석,김명철 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8

To evaluate the effects of Zoletil (tiletamine-zolazepam) that have been widely used for the chemical restraint and anesthesia of primates, on physiologic alteration, blood gas analysis and anesthetic duration in the Japanese macaque(Macaca fuscata), this study was carried out. Zoleril was administered by intramuscular injection, Evaluation of temperature, heart rate, respiration rate and blood gas analysis were performed before administration ancl at 1,10, 20, 30, 40, 50 and 60 min after administration, and induction and maintenance time was recorded. There was no significant difference in heart rate, PCO₂PO₂after Zolcril administration and temperature, respration rate, pH were significant difference compared with those of before administration, The induction time was 2.5±l.Omin and maintenance time was 86±23.2min. It was considered that Zoletil could he usefully used for the sedation and immobilization of Japanese macaque reared in zoological garden.

소동물 임상에서 침술마취의 적용

김명철,김덕환,전무형,홍성혁,박창식,이재일,이수진,김영석 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8

Pain modification is an important part of traditional acupuncture therapies. However, the idea of using acupuncture to alleviate pain has been greatly expanded in the last four decades. It has reached the level that acupuncture may be used as a substitute for conventional anesthesia. Surgical analgesia can be produced by methods involving peripheral or central stimulation, such as Acupuncture Analgesia (AA). The most common method is Electro-Acupuncture Analgesia (EAA). using a special electrostimulator attached to needles in acupuncture points. The major advantages of AA or EAA are its safety in high-risk patients and excellent post-operative pain relief, freedom from complications and enhanced healing which follows surgery under AA. The major disadvantages are the long induction period (10-40 minutes) and variable degrees of analgesia, even in skilled hands. The mechanisms of AA Involve stimulation of peripheral sensory nerve, spinal cord and supraspinal areas (thalamus, midbrain and hypothalamus) AA can be used effectively in dog. The method has its advantage, and disadvantages.

대동물 임상에서의 침술마취의 적용

김명철,김덕환,전무형,홍성혁,박창식,이재일,이수진,김영석 충남대학교 형질전환복제돼지연구센터 2004 논문집 Vol. No.8

Acupuncture is used to treat pathological conditions and to prevent pain from arising. The pathological conditions that can be treated can be painless or painful conditions. Acupuncture analgesia (AA) is a specific form of acupuncture; the stimulation of the acupuncture points must be strong and long (about 15 to 30 minutes) before a local or general analgesia or hypalgesia will develop. Development of modern AA began in the late fifties. Effectiveness of acupuncture in alleviation of pain was quickly noticed and brought to the medical researchers and surgeons. Through their diligent pursuit, AA has been established as a viable alternative for relief of pain and substitution of conventional anesthesia. In veterinary medicine. early successful applications of AA to surgery of domestic animals were reported in the late sixties. Local or regional anesthesia is often preferred to general anesthesia in cattle. Acupuncture was effective in inducing analgesia. Regional electroacupuncture analgesia is potentially useful for standing surgeries in cattle. Some standing surgeries may be easily accomplished using electroacupuncture anesthesia.

대동물 임상에서의 침술마취의 적용

김명철,김덕환,전무형,홍성혁,박창식,이재일,이수진,김영석 충남대학교 수의과대학 동물의과학연구소 2002 動物醫科學硏究誌 Vol.10 No.-

Acupuncture is used to treat pathological conditions and to prevent pain from arising. The pathological conditions that can be treated can be painless or painful conditions. Acupuncture analgesia (AA) is a specific form of acupuncture: the stimulation of the acupuncture points must be strong and long (about 15 to 30 minutes) before a local or general analgesia or hypalgesia will develop. Development of modern AA began in the late fifties. Effectiveness of acupuncture in alleviation of pain was quickly noticed and brought to the medical researchers and surgeons. Through their diligent pursuit, AA has been established as a viable alternative for relief of pain and substitution of conventional anesthesia. In veterinary medicine, early successful applications of AA to surgery of domestic animals were reported in the late sixties. Local or regional anesthesia is often preferred to general anesthesia in cattle. Acupuncture was effective in inducing analgesia. Regional electroacupuncture analgesia is potentially useful for standing surgeries in cattle. Some standing surgeries may be easily accomplished using electroacupuncture anesthesia.