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      • 상 요추 추간판 탈출증의 수술적 치료

        조태현,송준혁,김명현,박향권,김성학,신규만,박동빈 梨花女子大學校 醫科大學 醫科學硏究所 2000 EMJ (Ewha medical journal) Vol.23 No.3

        Objectives : Lumbar disc herniations at the L1-L2, L2-L3, and L3-L4 level are rare. The purpose of this study is to observe the variable clinical finding of upper lumbar disc herniations and to provide proper treatment modality. Patients and Methods : Between 1998 Jan. and 1999 Dec., seventeen patients with upper lumbar disc herniations who were undergone surgery in our institute were retrospectively evaluated. Patients were evaluated based on following factors : age, sex, aggravating factor, symptoms and signs type of disc herniation, type of surgery, and outcome of post-surgery. Results : The incidence of lumbar disc herniation at the level of L1-2, L2-3 and L3-4 is 6.1% with declining frequency as the level ascends. The peak age incidence is 6th decade in both sex. Preoperative symptomes and signs are variabe. In sixteen cases, posterior approach was done. In these cases, twelve cases were performed microscopic partial hemilaminectomy, and four cases with spinal stenosis were performed total laminectomy and posterior screw fixation with bone fusion. In one case, lateral extracavitary approach was done. In results of operation, fourteen cases showed more than good grade(82%). Conclusion : The age incidence of lumbar disc herniations at the level of L1-2, L2-3 and L3-4 older than lumbar disc herniations at the lower level of L4-5 and L5-S1. The signs and symptoms are variable. In our cases, most of the patients were performed posterior approach with microscopic partial hemilaminectomy except the patients combined spinal stenosis. One case was performed a lateral extracavitary approach because the risk of the cord and cauda equina injuries. The prognosis of upper lumbar disc herniations after treatment with only microscopic partial hemilaminectomy and diskectomy is comparable with the prognosis of lumbar disc herniations at the lower level.

      • SCOPUSSCIEKCI등재
      • 호박식초의 개발

        조학래,허성호 동의공업대학 1998 論文集 Vol.24 No.1

        In developing pumpkin vinegar, the cabohydrates of ripe pumpkin were hydrolyzed with hydrolyzing enzymes such as Termamyl, Viscozyme, Rapidase and Dextrozyme, using the substrates of alcohol and acetic acid fermentation. The sliced pumpkin was heated for 1 hour at 110℃, then crushed. The reducing sugar concentration 11.2∼11.9% of crushed pumpkin was acquired by the enzymatic hydrolysis reaction for 24 hours that the added enzymes concentration were 0.3∼0.5% to total pumpkin volumes at 50℃. In ethanol fermentation of pumpkin hydrolysate with Sacchromyces cerevisiae. optimum reducing sugar concentration of the hydrolysate adjusted by adding dextrose was revealed as 20%. In this condition the ethanol concentration of the hydrolysate was reached 12.0% by cultured for 7days at 30℃. The pumpkin hydrolysate adjusted to ethanol concentration 6.0% with water was inoculated with Acetobacter aceti and cultured statically for 30days at 30℃. The maximum acidity 6.5% of the solution was achieved.

      • 항응고제 치료와 연관된 자발성 근육내 혈종

        김수성,조재훈,이학승,박현영,장혁,김요식,조광호 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

        항응고제 치료의 주된 합병증은 출혈로서 주로 뇌실질과 복강 내에 발생하며 사지 근육에 발생하는 근육내 혈종은 매우 드문 것으로 알려져 있다. 이러한 항응고제 치료 후 발생하는 자발성 근육내 혈종은 발생빈도가 드물 뿐 아니라, 심부정맥혈전증과 그 증상이 유사하여 감별하기가 쉽지 않다. 저자들은 항응고제 치료 후 운동 마비가 발생한 사지 근육에서 자발성 근육내 혈종이 발생한 증례를 경험하여 이를 보고한다. Spontaneous intramuscular hematoma(SIH) is an uncommon but serious bleeding complication of anticoagulation therapy that has received little attention. We present a patient of spontaneous muscular hematoma during anticoagulation therapy for acute stroke management. A-74-year old man was admitted with sudden onset of dysarthria and left hemiparesis. Brain MRI and MRA showed acute cerebral infarction along right middle cerebral artery territory and severe stenosis of right proximal cervical internal carotid artery. During intravenous heparin treatment, he complained acute pain and swelling on left leg. Muscular CT showed enhancing focal soft tissue mass on left gastrocnemius muscle and ultrasonography demonstrated multiple hematomas on left gastrocnemius muscle. Treatment of heparin was stopped immediately. After conservative management for hematomas, symptoms were subsided.

      • 미생물을 이용한 페놀 폐수지처리에 관한 연구

        박상헌,심학보,이수구,서성조 서울산업대학교 산업대학원 1992 大學院論文集 Vol.1 No.1

        본 연구는 혼합 미생물을 이용한 페놀 함유폐수의 생물학적 처리에 관한 연구로서, 높은 페놀 농도에서의 이를 분해시킬 수 있는 균주를 개발하고 페널 함유폐수의 효과적인 처리를 위한 실험연구이다. 각종 공장폐수, 슬러지, 토양 등 40여종의 시료로부터 페놀 분해균을 선별하였으며, 페놀농도를 단계적으로 높여 미생물을 적응시킨 결과, 페놀농도 1,000ppm의 높은 농도에서도 잘 증식하며 페놀을 효과적으로 분해시킬 수 있었다. 혼합 미생물을 분리 동정한 결과, 우점종은Pseudomonas PI인 것으로 나타났다. 회분식 실험에서 초기 페놀농도, 균체량 및 glucose 농도 등을 변수로 실험하였느데, 페놀 분해속도는 시간에 따라 증가함을 나타내었다. 또한 페놀이 완전 제거되는데 소요되는 시간은 초기 페놀 농도에 비례하였으며, 균체 주입량에 다른 초기 MLSS농도의 대수식으로 나타낼 수 있었다. 연속식 활성 슬러지법에 의한 실험에 있어서, 본 실험조건에서 페놀이 완전 제거되는데 필요한 반응기내의 체류시간은 유입 페놀농도 500ppm인 경우 20시간이 소요되는 것으로 나타났다. This investigation was carried out to study the biodegradation of phenol in wastewater using mixed microorganisms. The mixed clutures of phenol degrading microorganisms were selected from various sources such as industrial wastewaters, sludges and soils. The mixed cultures could be adapted to high concentration of phenol by increasing the phenol concentration step by step. The phenol was degraded easily even up to 1,000ppm of phenol using these microorganisms. The predominant bacteria was isolated and characterized as Pseudomonas PI. In a batch system, the removal rate of phenol increased with time due to the lag time of microorganism adapation. The duration time during which phenol could be completely removed was linearly proportional to the initial phenol concentration. And the duration time(td) could be expressed as a funtion of logarithmic initial MLSS concentration(x) as follows. td=?? [8.68-In(x)] In a continuous system, the required residence time to remove phenol completely was found to be 20 hours and 35 hours 500 ppm and 800 ppm of influent phenol concentrations, respectively.

      • 이상형 스테인레스강의 크롬질화물 석출과 상 방위관계 연구

        최병학,김진우,고석민,조용석,김상식,이재현 국립7개대학공동논문집간행위원회 2002 공업기술연구 Vol.2 No.-

        Microstructures in the directionally solidified duplex stainless steels were investigated in order to understand the effect of nitrogen addition and its precipitation in the α phase. It was found that the addition of nitrogen causes the formation of fine precipitates in α matrix and segregation phases of nitrogen in the α/γ interface. Both the fine precipitates and the segregation phases were identified as CrN(fcc, a=4.18Å), as a coherent phase related to the α-bcc matrix with crystal relationship of (200) CrN//(01 ̄1)α and (1 ̄1 ̄1)CrN//(3 ̄2 ̄1)α.

      • 백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

        송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

      • KCI등재

        대학생의 정신건강에 관한 연구 (Ⅰ) : 1994학년도 조선대학교 신입생 일부를 대상으로 1994 Chosun University Entrants

        박상학,조용래 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.2

        본 연구는 본교 신입생들의 정신건강의 실태를 객관적으로 파악하고, 대학생의 정신병리에 대해 어떤 인구학적 및 심리사회적 변인들이 관련이 있는 지를 탐색적으로 고찰하고자 하였다. 1994년도 조선대학교 신입생 865명을 대상으로, SCL-90-R 및 저자들을 포함해서 김학렬 등이 개발한 1994학년도 조선대학교 신입생 실태조사 설문지를 실시하였다. 연구 결과, 1) 심리적 부적응자로 잠정 분류될 수 있는 학생의 비율이 조사 대상자 전체의 5.5%였으며, 남학생이 여학생에 비해 더 높았다. 2) 심리적 부적응 비율은 단과 대학, 재수 여부 및 부모생존(결손가정) 여부에 따라서 유의한 차이를 보이지 않았다. 3) 학생들의 정신병리와 심리사회적 변인들의 관계에서는 자기지각변인이 정신병리에 대해 가장 설명력이 큰 예언변인이었으며, 부모와의 친밀도와 고교생활 간의 상호작용 효과는 강박증 및 전반적인 심리적 부적응을 제외한 거의 모든 유형의 정신병리에 대해 유의하였다. 4) 성차는 심리적 부적응 및 간이 정신진단검사의 몇가지 임상척도에 대해 유의한 직접적인 효과가 있었으며, 또한 정신병리와 심리사회적 변인의 관계에 유의한 중재변인으로 작용하였다. 결론적으로, 조선대학교 신입생들 중 심리적 부적응자로 잠정 분류될 수 있는 학생의 비율은 몇개의 다른 대학들에 비해 낮았으며, 또한 본 연구의 결과들은 대학생의 정신건강에 대한 예방적 치료적 측면에서 중요한 기초 자료를 제공하고 있다고 사료된다. Objectives : The purposes of this study are to identify the current status of the mental health of Chosun university(CU) entrants and to explore the relationship between some demographic and psychosocial variables and psychopathology. Methods : Korean version of symptom checklist-90-revision(SCL-90-R) and the questionnaire for the survey on 1994 Cu entrants' developed by Hack-Ryul Kim et al. including authors were administered to entrants(N=865) admitted to CU in 1994. Results : 1. The percentage of entrants tentatively classifiable as psychologically maladjusted was 5.5% the total subjects surveyed, and was higher in males than in females. 2. But in that percentage the differences were not statistically significant between a) colleges, b) the groups who did or didn't experience failures in a college-entrance exam, and c) the groups who do or don't have living parents, respectively. 3) Of several psychosocial variables, self-perception was the most powerful predictor variable on the psychopathology of entrants, the interaction effect of the intimacy with parents and high school life was also significant. 4) As for sex, its direct effect on psychological maladjustment and certain scales in SCL-90-R was significant and it also played a role as a significant moderator in the relationship between psychosocial variables and psychopathology. Conclusion : It is concluded that the percentage of entrants tentatively classifiable as psychologically maladjusted in CU is lower than in some other universities, and that these results provide important basic data for the mental health of university students in terms of prevention and treatment.

      • 액체막법에 의한 중금속이온의 분리 및 회수

        曺文換,丁學鎭,이상인,金振浩,金始中 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

        거대고리 리간드는 금속이온과 선택적으로 결합하는데, 이를 이용하여 에멀젼 액체막을 통한 금속이온의 이동에 관하여 연구를 수행하였다. 금속이온은 유기층에 있는 운반체에 의하여 source phase에서 receiving phase으로 이동한다. 운반체로는 거대고리 리간드인 DBN_(3)O_(3)를 사용하였다. 여기에서 에멀젼 액체막을 통한 금속이온의 이동에 관한 요인과 어떤 금속이온의 선택적 분리에 관하여 검토하였다. 금속이온과 거대고리 리간드 그리고 금속이온과 receiving phase내에 있는 음이온에 대한 안정도 상수를 금속이온의 선택적 이동에 대한 척도로 조사하였다. 납이온이 혼합 용액에서 다른 금속이온보다 높은 이동속도를 나타내었다. Receiving phase내의 음이온이 금속이온의 이동에 중요한 역할을 한다. Receiving phase내에 있는 NO_(3)^(-)을 S_(2)O_(3)^(2-) 대치하면 이동량이 증가함을 보였는데 이는 Pb^(2-)-S_(2)O_(3)^(2-) 상호작용이 Pb^(2+)-NO_(3)^(-) 상호작용보다 크기 때문이다. Macrocyclic ligand has been know to selectively bind with metal ions so that ability applied for the transport of metal ions across the emulsion liquid membrane in this study. The metal ions are transproted from the source phase to the receiving phase by the carrier of the organic phase. Several factors involved in the transport of metal ions acrose the emulsion membrane we reported here and these factors proveided the informations for the selective seperation of some metal ion. Stability constants for cation-macrocyclic ligand and metal ion-anion receiving phase interaction are examined as parameters for the prediction of metal ion transport selectivities Pb^(2+) was transported higher rates than the other metal ions in the mixture solution. The interaction of metal ion to anion in receiving phase is important. S_(2)O_(3)^(2-) in replacement of NO_(3)^(-) in the receiving phase enhances the transport of pb^(2-) since Pb^(2-)-S_(2)O_(3)^(2-) interaction is greater than Pb^(2+)-NO_(3)^(+) interaction.

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