심리적 안전이 창의성에 미치는 영향: 성장마인드셋과 조직지원인식의 매개효과를 중심으로

최우수(Choi, Woo-Su),오상진(Oh, Sang-Jin) 한국경영교육학회 2020 경영교육연구 Vol.35 No.5

[연구목적] 본 연구는 불확실한 경영 환경 속 기업에게 혁신 수단으로서 창의성을 제시하기위해, 심리적 안전이 창의성에 미치는 영향과 그 과정에서 성장마인드셋, 조직지원인식과의 관계를 실증하여, 창의성 제고를 위한 실용적 방안을 제시하고자 한다. [연구방법] 국내 기업에 근무하는 다양한 업종의 구성원 총 420명에게 설문지를 배부하여 353명에게 자료를 수집하였다. 심리적 안전, 창의성, 성장마인드셋, 조직지원인식과 관련된 이론 및 선행 연구를 토대로 가설을 설정하였으며, 통계 도구로는 CFA를 통해 신뢰도와 타당성을 검증하였고, 가설검증을 위해 SPSS25, AMOS25, Macro Process3.0을 사용하였다. [연구결과] 연구 모형에 대한 가설 검증 결과 심리적 안전은 성장마인드셋, 조직지원인식, 창의성에 유의한 정(+)의 영향을 주는 것으로 나타났으며, 성장마인드셋과 조직지원인식의 매개효과도 유의한 것으로 나타났다. [연구의 시사점] 본 연구는 기업 현장의 조직문화 요인과 창의성 간의 관계를 동기부여 이론으로 검증했다는데 의의가 크다. 특히, 창의성을 특별한 재능 소유자의 전유물이 아니라 조직 문화의 변화를 통해 구성원들에게 확산시킬 수 있는 혁신의 도구로 제안했다는 점에서 시사점이 있다. [Purpose] This study aims to present creativity as a means of innovation to companies in uncertain business environment, demonstrate the impact of psychological safety on creativity and its relationship with growth mind-set and perceived organizational support in the process, and suggest practical measures to enhance creativity. [Methodology] Data were collected from 353 members. Hypothesis was set based on theories and previous studies related to psychological safety, perceived organizational support, growth mind-set and creativity. The collected data were reviewed for reliability and validity through CFA, and hypothesis verification was performed using SPSS 25, AMOS 25, and Macro Process 3.0 by Bootstrap. [Findings] Psychological safety was found to have a significant positive effect on growth mind-set, perceived organizational support and creativity, and the mediating effects of growth mind-set, perceived organizational support were also significant. [Implications] This study is significant in that it has verified the relationship between organizational culture factors and creativity at corporate sites with the theory of motivation. In particular, creativity is not the exclusive property of a particular talent owner, but it has implications for spreading to members through changes in organizational culture and, through this, proposed as a tool for innovation.

근대 초기 밀매음 여성의 문화 표상-은근자(慇懃子)를 중심으로-

우수진(Woo, Su-Jin) 우리문학회 2023 우리文學硏究 Vol.- No.79

이 논문은 근대 초기에 은근자 또는 은군자라고 불리며 극장이나 공원, 거리 등에서 호객했던 밀매음 여성에 주목하고자 한다. 이들은 이 시기의 다른 성노동 여성이었던 기생이나 창기에 비해 상대적으로 논외되어 왔다. 성매매는 일부일처제라는 근대적인 가족제도에 위배되는 것이었지만, 많은 사람들의 비판과 반대에도 불구하고 필요악으로 제도화되었다. 그리고 그 결과 제도 밖의 성매매인 밀매음은 공창보다 더 불온하고 위험한 것으로 여겨졌다. 밀매음은 근대 사회가 만든 인위적인 제도의 모순적인 균열 그 자체였다. 성매매는 단순히 합법과 불법으로 구분되지 않으며 나아가 윤리의 문제로 쉽게 재단할 수 없는 것이었다. 그리고 밀매음은 그 자체가 하나의 직업이나 정체성이었다기보다 사실상 여성과 빈곤이 교차하는 지점에서 발생하는 것이었기 때문에 하층민 여성은 언제든지 밀매음 여성이 될 수 있었기 때문이다. 은근자는 신문지상이나 문학, 연극 작품에서 대부분 부정적인 인물 내지는 악인으로 형상화되었다. 그리고 그 안에서 여성 섹슈얼리티는 주로 부도덕의 표상으로서 불온하고 위험한 것으로 재현되었다. 하지만 역설적이게도 이러한 재현을 통해 여성의 섹슈얼리티는 공공적으로 가시화되었으며, 결과적으로 성(적인 것)을 사회적으로 확산시켰다. This thesis examines the women known as Eungeunza (慇懃子, 隱君子). prostitutes who would seduce men in theatres, parks, and streets in the early modern period. This group of women has been relatively unstudied compared to other sex workers of this period, such as Gisaeng (妓生) or Changgi (娼妓). Prostitution violated the modern monogamous family system but was institutionalized as a necessary evil. As a result, illicit prostitution ― so-called Eungeunza ― was regarded as more disturbing and dangerous than regular prostitution. However, Eungenza represented a contradictory crack in the artificial system of modern society. This is because prostitution cannot be simply divided into legal and illegal, furthermore, it cannot be easily judged ethically. The critical discourse and regulation surrounding Eungeunza reproduced a public perception of female sexuality as rebellious and dangerous. This representation of Eungenza′s sexuality eventually permeated society. Even in modern literature and plays, they had been characterized as individuals who freely express their desires and sexuality often lacking morals and social norms. In this regard, Kim Woo-jin’s play ″Lee Young-nyeo(李永女)″ stands out as an exceptional example of naturalism and modern play of naturalism.

전자구개도(EPG)를 이용한 한국어 치경마찰음 /ㅅ, ㅆ/의 조음운동적 특성

김지영(Ji-Yeong Kim),우승탁(Seong-Tak Woo),김미진(Mi-Jin Kim),오다희(Da-Hee Oh),김수진(Su-Jin Kim),하지완(Ji-Wan Ha) 한국언어청각임상학회 2021 Communication Sciences and Disorders Vol.26 No.2

배경 및 목적: 본 연구는 전자구개도를 사용하여 한국어의 치경마찰음인 /ㅅ/와 /ㅆ/를 조음운동적 측면에서 비교 분석해보고, 치경마찰음 조음 시 나타나는 혀-구개 접촉에 관한 정보를 제공하기 위한 목적으로 시행되었다. 방법: 한국어가 모국어이며 발음에 문제가 없는 정상 성인 5명이 전자구개도를 착용하여 치경마찰음을 분절음 차원에서뿐 아니라 단어 내 위치 및 모음문맥을 달리하여 녹음한 후 팰라토그램을 분석하였다. 결과: 그 결과, /ㅅ/와 /ㅆ/는 협착의 너비와 혀-구개 최대접촉구간에서 유의한 차이를 보였다. /ㅆ/에서 협착의 너비가 더 좁고 전체 혀-구개 접촉구간은 더 넓게 나타났다. 단어 내 위치에 따른 차이는 유의하지 않았지만, 고모음인 /ㅣ/ 문맥에서는 저모음인 /ㅏ/에 비해 협착의 위치가 후방화되었으며, 지속시간도 가장 긴 것으로 나타났다. 또한 혀-구개 접촉 구간도 가장 넓게 나타났다. 논의 및 결론: 본 연구는 전자구개도를 사용하여 한국어 치경마찰음의 혀와 구개 접촉에 관한 정보를 제공했다는 점에서 그 의의를 갖는다. 또한 본 연구의 결과는 한국형 전자구개도의 개발의 기초자료로써 그 의미가 있다. Objectives: The present study is aimed an electropalatographic investigation of Korean fricatives /s/ and /s*/. All data from this study is based on the production of 5- adult speakers who speak Korean as their first language. Methods: Electropalatography (EPG) is an instrumental technique for showing tongue and palate contact during speech. The participants recorded /s/ and /s*/ in CV (/si/, /sɑ/, /su/, /s*i/, /s*ɑ/, /s*u/) and VCV (/ɑsi/, /ɑsɑ/, /ɑsu/, /ɑs*i/, /ɑs*ɑ/, /ɑs*u/) context using EPG and then, four variables were analyzed: row of medial groove (RMG), medial groove width (MGW), medial groove length (MGL), and maximum contact frame (MCF). Results: There was significantly greater medial groove width and maximum contact frame for / s*/ compared to /s/. The difference between /si/ and /sɑ/ was also found in the row of medial groove, medial groove width and maximum contact frame. /si/ was produced further back, and had a longer medial groove length. Also, it showed more total tongue-palate contact than /sa/. Conclusion: A various range of palatal contact patterns were found between typical adults for perceptually normal /s/ and /s*/. The results provided the information about tongue–palate pattern of Korean fricatives /s/ and /s*/. These findings would be utilized to build the basic data and useful information for Korean EPG system.

당뇨병 환자에서 혈장 Thrombin-Antithrombin Ⅲ 및 Plasmin-α_2-Plasmin Inhibitor 복합체의 임상적 의의

김경욱,김은숙,정상수,윤수지,박우일,이준희,남수연,안철우,문병수,김경래,차봉수,송영득,임승길,이현철,허갑범 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.5

연구배경:당뇨병 환자에서 혈액응고 및 섬유소용해 체계의 이상경향이 있어 그 결과로 여러 혈관합병증의 발생위험이 높다는 사실은 널리 알려져 있다. 그 기전은 아직 확실히 밝혀지지 않았으나, 고혈당으로 인한 혈장 단백질들의 비효소성 당화작용이나 산화성 스트레스로 인한 유리 라티칼 작용으로 응고항진이나 섬유소용해 활성의 저하를 유발하는 것으로 생각되고 있다. 최근 응고 및 용해인자와 그 억제자의 복합체들의 증가가 이 상태를 비교적 예민하게 반영한다고 알려져 있다. 방법:본 연구에서는 당뇨병 환자 101명과 정상 대조군 20명에서 혈장내 thrombin­antithrombin complex(TAT)와 plasmin­α₂­plasmin inhibitor complex(PIC)를 측정하여 비교하고, 당뇨병 환자에서 미세혈관 합병증과 대혈관합병증의 유무에 따른 차이와, 이미 혈관 질환의 위험인자로 알려져 있는 인자들간의 상관성을 알아보고자 하였다. 결과:1. 환자의 분포를 살펴보면 혈관합병증이 있는 군은 85명, 혈관합병증이 없는 군은 16명이었고, 평균연령은 각각 57.9±14.1세, 49.9±16.6세로 혈관 합병증이 있는 군에서 더 나이가 많았고, 체질량지수는 23.2±3.4㎏/㎡, 24.1±3.4㎏/㎡로 두 군간 유의한 차이는 없었다. 또 두 군간의 혈압 및 HbA1c, 공복혈당 및 인슐린과 C­peptide, 총 콜레스테롤, 중성지방, HDL­콜레스테롤, Lp⒜는 유의한 차이가 없었고, 미세혈관합병증이 있는 군에서 당뇨병의 유병기간이 길었다. 2. TAT 및 PIC의 농도는 정상 대조군에서는 2.8±1.2 ng/mL, 240.4±69.7 ng/mL이었고, 당뇨병 환자군에서는 9.5±22.6 ng/mL, 472.2±258.7 ng/mL이었다. TAT와 PIC 모두 당뇨병 환자군에서 정상 대조군에 비해 유의하게 증가되어 있었고(p<0.001), TAT/PIC ratio는 두 군간 차이가 없었다. 3. 당뇨병 환자의 혈관합병증에 따른 TAT 및 PIC, fibrinogen 농도는 합병증이 없는 군은 각각 4.1±2.4ng/mL, 362.2±272.0ng/mL, 322.7±102.4mg/mL으로 PIC와 fibrinogen의 증가를 보였으나, 연령을 보정한 후에는 통계학적 유의성은 없었다. 또 대혈관 합병증군에서는 각각 6.0±4.9 ng/mL, 507.4±321.6 ng/mL, 427.1±194.7 mg/dL이었으며 미세·대혈관 합병증군에서는 10.4±6.4 ng/mL, 484.8±269.7 ng/mL, 388.4±132.4 mg/dL으로 TAT의 증가를 보였으나 역시 연령을 보정한 후에는 통계학적 유의성은 없었다. 4. 미세혈관합병증군에서 HbA1c(>8%)가 높은 군의 PIC 농도가 유의하게 높았고(p=0.049), 대혈관합병증군에서 HbA1c(>8%)가 높은 군의 총 콜레스테롤 농도가 유의하게 높았다(p=0.042). 5. 총 당뇨병 환자군에서 PIC는 fibrinogen과 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며(r=0.47, 0.31,-0.25), 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다(r=0.67). 결론:이상의 결과에서 혈장 TAT 및 PIC 농도는 당뇨병 환자에서 정상 대조군에 비해 의미있게 증가되어 있었고, 당뇨병 환자군에서는 연령의 증가와 유병기간이 혈액응고항진 및 용해의 장애에 큰 역할을 함을 알 수 있었으며, 총 당뇨병 환자군에 PIC와 HbA1c와 양의 상관관계를, BMI와 음의 상관관계를 보였으며 혈관 합병증이 없는 당뇨병 환자군에서만 TAT는 HbA1c와 양의 상관관계를 보였다. 따라서 당뇨병 환자에서 혈액응고 및 용해의 장애가 동반되어 있다고 볼 수 있으며, 혈장 TAT 및 PIC는 혈관합병증으로의 진행을 예측하는 지표로서 유용하리라 생각된다. 또 혈당조절정도와 상관성이 있으므로 혈당조절후에 추적검사를 시행하여 합병증의 예방이 가능한지 추후 연구가 필요하리라 생각된다. Background : Abnormality of coagulation and fibrinolystic system is known as a predisposing factor of vascular complication in diabetes. Although the pathogenesis is not well known, non-enzymatic glycation reaction and the increase in production of free radicals due to an increased oxidative stress may be linked to the hypercoagulibility and hypofibrinolytic activity. As indices of abnormality in coagulation and firinolysis in peripheral blood, plasma thrombin-antithrombin Ⅲ complex (TAT) and plasmin-α_2-plasmin inhibitor complex (PIC) were measured. The purpose of this study was to clarify whether hypercoagulability exists in diabetic patients with or without vascular complication. Methods : In our study, we measured plasma thrombin-antithrombin Ⅲ compelx (TAT) and plasmin-α_2-plasmin inhibit or complex (PIC) in 101 diabetic subjects and 20 controls. Comparing TAT and PIC levels in diabetic microvascular complication group, diabetic macrovascular complication group and controls, we examined correlation between risk factors associated with diabetic vascular complication. Results : 1. The group with diabetic vascular complication was older than group without complication. There was no significant difference in BMI, blood pressure, HbA_ic, blood sugar level, insulin, C-peptide, serum creatinine, total cholesterol, triglyceride, HDL-cholesterol, Lp (a) between two groups. The group with diabetic microvascular complication had longer duration of diabetes. 2. Concentration of TAT and PIC were 2.8±1.2 ng/ mL, 240.4±69.7 ng/ mL in controls and 9.5±22.6 ng/ mL, 472.2±258.7 ng/ mL in diabetic patients, respectively. TAT and PIC were significantly higher in diabetic patients than in control (p<0.001). But TAT/PIC ratio was no significant difference between two groups. 3. In diabetic patients, concentration of TAT and PIC and fibrinogen were respectively 4.1±2.4 ng/ mL, 362.2±272.0 ng/ mL, 322.7±102.4 mg/ dL in group without vascular complication and 5.3±4.1 ng/ mL, 529.5±258.7 ng/ mL, 374.9±106.2 mg/ dL in group with microvascular complication, which group had increase in PIC and Fibrinogen but no significance after correction of age. Concentration of TAT and PIC and Fibrinogen were 60.±4.9 ng/ mL, 507.4±321.6 ng/ mL, 427.1±194.7 mg/ dL in macrovascular complication, and 10.4±6.7 mg/ mL, 484.8±269.7 ng/ mL, 388.4±132.4 mg/ dL in combined vascular complication which group showed increase of TAT but also had no significant increase after correction of age. 4. In diabetic microvascular complication patients, group of high HbA_1c (>8%) (p=0.049) had significant high PIC concentration. In diabetic macrovascular complication patients, group of high HbA_1c (>8%) (p=0.042) had significant high total cholesterol concentration. 5. In all diabetic patients, PIC was positively correlated with fibrinogen and HbA_1c and negatively correlated BMI (r=0.47, 0.31, -0.25). Only in daibetic patients without angiopathy, TAT was positively correlated with HbA_1c (r=0.67). Conclusion : In this study, plasma TAT and PIC concentration significantly increased in diabetic patients compared with controls, and PIC was increased in group with microvascular complication, TAT were increased in group with combined micro macrovascular complication. However, there was no significance relationship existed when correctinf for age. PIC was correlated with HbA_1c. TAT was correlated with HbA_1c only in the group without angiopathy. Abnormality of coagulation and fibrinolysis were combined in diabetes, plasma TAT and PIC can be used as an index of vascular complication. Also we found the correlation with the degree of the blood glucose control. Therefore we need follow up study for the possibility of prevention of vascular complication after controlling the blood glucose to age-matched patients (J Kor Diaabetes Asso 25:354~363, 2001).

혈관 생성 억제 제를 투여한 신생마우스 폐 조직에서 Retinoic acid의 세포자멸사의 억제

주선영 ( Sun Young Ju ),조경아 ( Kyoung Ah Cho ),유경하 ( Kyung Ha Ryu ),우소연 ( So Youn Woo ),박은애 ( Eun Ae Park ),조수진 ( Su Jin Cho ) 대한주산의학회 2008 Perinatology Vol.19 No.1

목적: Retinoic acid는 폐포 재생에 중요한 역할을 하는 것으로 알려져 있어서 미숙아의 기관지폐이형성중의 예방에 사용되고 있다. 기관지폐이형성중의 병태생리는 미숙한 폐의 내피세포와 외피세포의 세포자멸사를 일으킴과 관련이 있다. 이에 본 연구에서 VEGFR2 억제가 신생 폐에서 세포자멸사를 증가시키는지, 또 retinoic acid의 투여가 본 폐 발달 억제 동물모형에서 세포자멸사를 억제하는지 알아보고자 하였다. 방법: VEGFR2 억제제인 SU1498을 생후3일된 마우스에 주사하고, 폐포발달이 이루어지는 그 후 10일간 retinoic acid나 위약을 주사하였다. 형태학적인 분석을 하였고, 세표자멸사를 비교분석하기 위해서 TUNEL 염색과 Annexin V을 표지자로 FACS출 시행하였다. 자멸사한 세포를 확인하기 위해서 동일초점 현미경으로 분석하였다. 결과: SU1498를 주사한 마우스에서 폐포면적과 평균폐포용적이 의미 있게 감소하였다. 세포자멸사도 약 3배 의미 있게 증가하였다. 자멸사한 세포는 내피세포와 상피세포에 분포하였다. Retinoic acid를 주사한 약 50%의 세포자멸사가 감소하였고, 형태학적으로 정상에 가까운 폐포 발달이 유지되었다. 결론: VEGFR2 억제를 하면 내피세포와 상피세포의 세포자멸사가 증가되면서 폐 발달이 저해되었다. 이어서 retinoic acid를 주사하면 세포자멸사가 억제되어 폐 발달유지에 도움이 되었다. 이러한 retinoic acid에 의한 세포자멸사의 억제가 기관지폐이형성증 예방에 기여할 것으로 추정된다. Background: Retinoic acid is known to play a role in alveolar regeneration and is used in the prevention of bronchopulmonary dysplasia (BPD) in premature infants. Many factors involved in the pathogenesis of BPD induce apoptosis of the endothelium and epithelium of the premature lung. We hypothesized that VEGFR2 inhibition would increase apoptosis in the newborn lung and retinoic acid would decrease apoptosis in our model of inhibited lung growth. Material and Methods: SU1498, a VEGFR2 inhibitor or vehicle was given to three-day-old mice. Subsequent retinoic acid or vehicle injection was given for ten days for the duration of alveolarization. Morphometric analyses were performed. Apoptosis was assessed with TUNEL staining and Annexin V staining. Co-localization of apoptotic cells with endothelial and epithelial cells was performed. Results: SUI498 injection reduced alveolar surface area and mean alveolar volume in newborn mice. Apoptosis was increased by three-fold in SU1498 injected mice. Apoptotic cells co-localized to endothelial and epithelial cells. Retinoic acid significantly reduced the degree of apoptosis by 50% in SU1498 injected mice and maintained lung development. Conclusion: VEGFR2 inhibition caused an arrest in lung development accompanied by an increase in apoptosis of endothelial and epithelial cells of the neonatal lung in mice. Subsequent retinoic acid treatment reduced apoptosis and we speculate that retinoic acid may preserve lung growth in bronchopulmonary dysplasia by inhibiting apoptosis in the neonatal lung.

Cilostazol의 항혈소판 응집작용과 sodium citrate의 농도에 따른 혈소판 응집율에 대한 연구

우수경,김영리,권광일 충남대학교 약학대학 의약품개발연구소 2000 藥學論文集 Vol.16 No.-

Cilostazol, 6- 〔4- (1-cyclohexyl- 1H-tetrazol -5-yl) butoxy〕 - 3, 4-dihydro- 2(1H)- quinolinone, is an antiplatelet/antithrombotic agent that has been used for treatment of chronic peripheral arterial occlusion. Cilostazol was studied for its inhibitory effects on platelet aggregation in vitro in rabbit plasma and in human plasma, and also for its antiplatelet effects ex vivo in rabbit after single oral administration. At time t=0, the rabbits were given a single oral dose of 14 ㎎/㎏ cilostazol. At 1, 2, 4, 8, 12, and 24 hours after drug administration, blood samples were taken for measurements of antiplatelet aggregation effect. Before the study of antiplatelet effects of cilostazol in rabbits, the effect of sodium citrate on platelet aggregation in various concentrations was studied to determine the optimal treatment. Cilostazol produced a potent inhibitory effect on platelet aggregation induced by adenosine diphosphate (ADP) in vitro. The maximum effect on antiplatelet aggregation was 14.4% and was appeared at 1 hour after drug administration. The optimum blood/anticoagulant (3.8% sodium citrate) ratio was 9 to 1, and 16 to 1 in human plasma and in rabbit plasma, respectively.

인공 피음처리에 따른 전나무의 생장과 엽록소 함량변화에 관한 연구

우수영,이동섭,권오규 한국농림기상학회 1999 한국농림기상학회지 Vol.1 No.2

This study was conducted to compare seasonal changes of height, diameter at root collar, biomass and chlorophyll contents of Abies holophylla seedlings grown in Sangju National University Nursery under different light intensities. Four light intensities were adopted using nylon net such as 100% sunlight (1800 μmol m^-2 s^-1), 75% of sunlight (1350 μmol m^-2 s^-1), 50% of sunlight (900 μmol m^-2 s^-1) and 25% of sunlight (450 μmol m^-2 s^-1). Planting density in four light intensities was 30 cm × 30 cm. In each treatment, 100 trees were planted and height, diameter at root collar, biomass and chlorophyll contents were measured. The highest height, diameter at root collar and biomass in Abies holophylla seedlings were observed at 100% full sunlight. Lowest chlorophyll contents (Chlorophyll a, b and total) were shown at 25% of sunlight, lowest light intensity treatment in this study. Growths and chlorophyll contents of Abies holophylla seedlings were strongly associated with light intensity. Photosynthesis has to be investigated in near future because photosynthesis and chlorophyll contents were strongly related to tree growth with long periods.

PCR을 이용한 국내 및 수입 축산물 유래 Listeria monocytogenes의 유전학적 분석연구

우용구,이수화,이철현,최정수,류재두,김영일,이오수,김봉환 한국수의공중보건학회 2003 예방수의학회지 Vol.27 No.2

One hundred-fifty two of Listeria strains were isolated from domestic chicken carcasses, a slaughter-houses from nationwide from 1996 to 1997 and imported livestock products from a ten foreign countries including the USA, China, France and Thailand. To substitute the laborious and time consuming procedures of clinical laboratory standard diagnostic methods, the rapid and specific multiplex PCR(M-PCR), which was designed to amplify a three kinds of genes simultaneously f3r specific detection and differentiation of L. monocytogenes(LM) by one step procedure, was established. The LM strains confirmed with M-PCR were analysed to their genetic diversities by RAPD using the two primers(D87 & MMTl), and also evaluated on their discriminatory abilities(na) between two primers. our study also conducted the REP-PCR and ERIC-PCR for evaluation of the possibility of REP and ERIC elements for genetic subtyping of LM strains. According to the REP-PCR and ERIC-PCR fingerprinting patterns, LM strains were divided into 7(ERIC-type) and 4(REP-type) major clusters at the relative clone cut off value of 80%. According to the computer analysis of PCR results using the GelCompar Ⅱ software, ERIC-PCR(DI=0.955) had expressed the most high discriminatory ability and followed by REP-PCR(DI=0.952), RAPD(D87; 0.954, MMT1; 0.937), in order. The combined analysis of the present PCR results was also expressed the reliable and useful discriminatory ability(DI=0.916). This study suggested that PCR based methods could be used as an reliable, reproducible, rapid, and highly discriminatory method for the genetic differentiation of genus Listeria.

담도에 국한되어 증상을 유발한 석회쓸개즙 2 예

윤성우,이지영,하경호,이수경,한나,배효근,박선자 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.2

Limy bile is a rare condition characterized by excessive precipitation of calcium carbonate in the gallbladder or bile duct. Recently we experienced two cases with obstructive jaundice in which limy bile in the common bile duct but not in the gallbladder for one case, and in the common bile duct and intra hepatic duct but not in the gallbladder for another case. The patients were treated by endoscopic sphincterotomy. Here, we report the cases and review the literature.

기하학적 궤도 제약조건에서 로보트의 최소시간 궤도궤획

우광방,홍수원 연세대학교 대학원 1987 延世論叢 Vol.23 No.1

In order to maximize the capability of robot and to execute the given task during the least minimum time, this paper presents the algorithm which enables robot manipulator to move between two points in Cartesian space optimally when it satisfies the constraints of the specified trajectory function and input torque constraints. Specifying traveling path between any two points in the task space, trajectory function is described by the parameters representing joints of the manipulator and by the single parameter representing the trajectory. The trajectory function is incorporated into the dynamic equation of robot in which change in its manipulator position is expressed in terms of change in the values of the parameters that produce optimal solution. Input force torque constraints are coverted to the parameters of the dynamic equation and there is no need to restrict the range of the input torque. Phase plane is implemented that consists of the pseudo velocity and position of the joints. The pseudo velocity is derived from characterisitcs of the dynamic equation, and the admissible range of the manipulator velocity is designed on the phase plane. The above algorithm is applied to operations of the manipulator which has prismatic joint and rotational joint, and computer simulation is carried out Under several constraints, the optimal trajectory is generated and the trajectory can traverse between two points in Cartesian space with minimum time.