대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

자발성 뇌지주막하 출혈 환자에서 최초 뇌실 크기의 임상적 의의

신일영,윤일규,윤석만,도재원,이경석,배학근,최순관,변박장 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1

The purpose of this study is to invesetigate the clinical significance of initial enlargement of ventricle in the patients who had aneurysmal SAH. Of the total 821 patients with aneursmal SAH who were registerd in SAH data bank system between 1989-1999, 307 patients who had been already measured in the size of ventricle at the time of admission, were studied retrospectively. The size of ventricle was calculated by bifrontal index. Normal size of ventricle was defined as 30% or less, mild enlargement was defined as 31 to 39%, and moderate enlargement of vertricle was defined as more than 39% in bifrontal index. The sizes of ventricle using bifrontal index were analysed according to the age, sex, blood pressure, consciousness at admission, medical history of hypertension, location of ruptured aneurysm, Fisher's grade on CT(computerized tomography) scan at the time of admission, cerebral vasospasm, intraventricular hemorrhage (IVH), performance of external ventricular drainage (EVD), and prognosis at discherge. Chi-square test and ANONA were used in the statistical evaluation. The results were as follows : 1) Of the 307 patients, 235(76.5%) had a mild to moderate enlargement of ventricle at the time of admission (more than 30% in bifrontal index). 2) The size of ventricle was enlarged according to the increase of age (p<0.05). 3) In the patients who had ruptured aneurysm on anterior cerebral artery, the size of ventricle significantly increased and showed a higher incidence in mild enlargement compared with moderate enlargement of ventricle (p<0.05). 4) The size of ventricle increased in th patients who had IVH and the EVD was more frequently performed in th patients who had the enlarged ventricle associated with IVH (p<0.05). 5) In the patients who had high Fisher's grade, the size of ventricle had a tendency to increase, but there was no statistical significance. 6) In the patients who had poor prognosis, the size of ventricle had a tendency to increase, but there was no statistical significance. Conclusively, the initial size of ventricle was enlarged in th aged patients, ruptured aneurysm on anterior communicating artery, high FIsher's grade, patients associated with IVH. Considering those factors, prediction for the enlargement of ventricle size may help to treat the patients suffering aneurysmal SAH.

특발성 경련질환으로 오인된 원발성 부갑상선기능저하증 1례

신성하,최정영,김준기,고영춘,조상욱,김순호,임중규 全南大醫大 2001 전남의대학술지 Vol.37 No.1

苛性소다 處理가 볏짚의 나이론주머니 消化率에 미치는 영향

辛炯泰,金永玉,魏筍英 成均館大學校 1980 論文集 Vol.28 No.-

Four Korean native male goats, weighing approximately 30㎏ each, were equipped with rumen cannulas to study the effect of different levels of NaOH treatment, of rumen incubation time and of different kinds on "nylon bag dry matter digestibility (NBDMD,%)" and "nylon bag organic matter digestibility (NBOMD,%)" of rice straws. The goat was housed individually in pen and was fed 600 grams (concentrate) daily, and fed rice straw and rincal blocks ad libiltum. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9 X 14 ㎝ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 24, 48 and 72 hours (Experiment 1) and 72 hours only (Experiment 2). They were washed, dried in an oven at 105℃ for 24 hours and weighed "NBDMD", and ashed in an muffle furnance at 600℃ for 2 hours and weighed "NBOMD". The results which were obtained with two experiments were as follows; 1. Nylon bag dry matter digestibility (NBDMD,%) and nylon bag organic matter digestibility (NBOMD,%) of NaOH treated straws were highly significant different (P<0.01) in different levels of NaOH treatment, of rumen incubation time and of different kinds of rice straws. 2. The relationship between mean NBDMD (%, Y_1) of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hours rumen incubation was: Y_1=2.93X_1+42.32(r=0.97^**) 3. The relationship between mean NBOMD (%, Y_2)of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hour rumen incubation was: Y_2=2.76X_1+41.32(r=0.96^**) 4. The orders of NBDMD (%) and NBOMD (%) for 5 kinds fo rice straws were Yooshin, Suwon 264, Milyang 23, Tongil and Akibre. Therefoare it is necessary to study more on the utilization of NaOH-treated new-bred rice straws for animal performance than old-bred rice straw as Akibare. 5. The optimal level of NaOH (%) for improving NBDMD and NBOMD from 5 kinds of rice straw on the basis of Dr. McCullough's theory was as follow: 6% NaOH for Yooshin, Suwon 264 and Milyang 23; 7% NaOH for Tongil and 8% NaOH for Akibare. 6. Crude protein, crude fiber, ADF, cellulose, lignin percent of 5 rice straws did not much different by chemical analysis. The orders of NBDMD (%) and NBOMD (%) for 5 kinds of rice straws did not same orders of the consitituents of chemical composition in rice straws.

초등과학 탐구수업 지도자료의 활용 실태

신영준,장명덕,배진호,권난주,여상인,이희순,노석구 한국초등과학교육학회 2005 초등과학교육 Vol.24 No.2

In this study, we had tried to present a plan for improving the actual conditions of practical utilization of teaching material for 6th grade science developed by Ministry of Education & Human Resources Development and distributed to all elementary schools in Korea. Also we presented ways of better utilization of the teaching material after investigating the actual conditions of practical utilization. A survey was made to investigate and collect all data in the major metropolitan cities, the Kangwon, Chungcheong, Honam, and Kyeongsang area, respectively. We surveyed 316 6th grader teachers to investigate the actual conditions of distribution and utilization of teaching material as a general research. In addition, we surveyed 46 teachers to investigate the organization and content of teaching material as a particular research. The results are as follows. First, the teaching material was not approximately transmitted and kept to 6th grader teachers. Second, the utilization guide was not made. Third, it was reported that the thematic divisions of teaching material was a strong point, but the less detailed experiment manual was a weak point. Fourth, the consideration of content difficulties and simplicity was necessary to improve the material. Fifth, additional items should be included in the introductory presentation, convenience of reorganization, activity material causing learning interest, guidance of substitution experiment, and more concrete notice of experiment activity. Finally, there were positive responses of more than 4.0 point of Likert scale (1 to 5 point scale) in detail investigations of thematic items, which could have possibility that the teaching material was helpful to elementary school science field.

인체장염유발 Campylobacter jejuni의 생육특성 및 Polymerase Chain Reaction에 의한 신속 검출

신순영 서울여자대학교 대학원 1999 論文集 Vol.- No.7

인체 장열유발균인 Campylobacter jejuni의 식품으로의 오염방지와 그 검출을 위하여 순수 배양조건과 우유, 닭고기 등의 식품에 균을 접종하여 그 생육을 온도 별로 관찰하고 그 검출을 위한 polymerase chain reaction을 시도하였다. Campylobacter jejuni는 최적온도 42℃나 저온 5℃에서 보다 오히려 25℃ 상온에서 사멸이 빨랐다. Polymerase chain reaction은 16S rRNA 유전자에 근거한 primer, pA와 pB를 이용하여 whole cell을 DNA 추출없이 직접 DNA templete로 이용하였으며, 이 때 Campylobacter jejuni의 검출 감도는 1PCR 반응당 균수 1-10¹이었다. 이 감도는 순수 배양액에서나 우유 혹은 닭고기 등의 식품에서도 거의 같은 수준으로 유지되었다. 이러한 결과는 polymerase chain reaction을 이용한 Campylobacter jejuni의 식품으로 부터의 적용에 있어서 실용 가능성을 제시하였다. The provide more information on the enteric pathogen Campylobacter jejuni in the view of food sanitation, survival characteristics of two strains of C. jejuni and the polymserase chain reaction(PCR) with pA and pB pair based on the 16S rRNA gene for the sensitive and specific detection in the different conditions were investigated. When 10? Or 10³ per mL of C. jejuni cells were inoculated in the supplemented Brucella broth and kept at 42℃, 25℃ and 5℃ under the static aerobic condition for 7 days, organisms exponentially proliferated to a>10?, even in the 10³ per mL inoculated-sample at 42℃ for 1-2 days and the considerable level of viability maintained during 7 days. At 5℃, most of the initial level of organisms survived at the early period and only a < 0.5-log? Cells decreased during the 7 days. At 25℃, a remarkable number of C. jejuni declined within 1-2 days and showed undetectable level of cells after 4 days. The results suggest that C. jejuni contaminated to food can survive at the refrigeration temperature whereas they are sensitive at the room temperature. For the application of PCR, six oligonucleotides were utilized in an amplification experiment and PCR products of predicted sizes were generated from whole cells and boiled cell lysates at the same intensity. In the PCR using the pA and pB primer pair, the detection limit of C. jejuni was the level of 10¹ bacteria cells or less in both the pure culture and milk and chicken enrichment samples. The PCR method using a primer pA and pB was repeatable and specific for the detection of C. jejuni in food. It is suggested that PCR is a very potential method to detect C. jejuni which causes disease with low number of cells in food.

「음식디미방」에 수록된 전통음식의 향약성에 관한 고찰

신민자,이영순,최수근 동아시아식생활학회 2001 동아시아식생활학회지 Vol.11 No.5

The pharmaceutical effects of Korean traditional foods made in 「Eumsikdimibang」were studied. Eumsikdimibang is a respresentative ancient book of cooking, which was published in 1653 by Mme, Jang. The type of food in Eumsikdimibang were Guksu(wheat vermicelli as like western noodles), Mandu(bun stuffed with seasoned meat and vegetables), Guk(soup), J'IM(steam meat or fish). Chae, Noorumi, Hyae(sliced raw fish), Jockpyun(jellied beef soup), Jockgall(salted seafood), Kimchi, Juk(skewer or broach), Jhee. Sun(steaming of stuffed vegetable), Bockuem, Jeon(pan fried fish). Gui(meat or fish grilled with seasoning), Dock(Korean rice cake), Jabgwa, Beverage and Junggwa. Each Korean foods has a phamarceutical action: enhancement of physical activity, thirst elimination, detoxication and treatment disease.

古代의 韓ㆍ中ㆍ日 醫藥交流 : 「일본서기」를 중심으로 indicated in 「Ilbonseogi」

신순식,최환수,양영준,홍원식 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

『Ilbonseogi』(edited A.D.720) was studied to investigate the medical and pharmaceutical exchange among ancient Korea, China and Japan. It seemed that Korean and Chinese traditional medicine was introduced to Japan through Korea. It was also shown in 『Ilbonseogi』 that Koreans who lived in China and Japan during that time seemed to have active medical idea exchange. From various facts indicated in 『Ilbonseogi』, it was believed that Korean and Chinese traditional medicine was the basis for the foundation of Japanese traditional medicine.

폐분체 도료의 재활용 방안에 관한 연구

신동철,김영훈,이순기,김경원,신선명,강헌찬 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.1

With the progress of industry, the much more demand of paint around us grows rapidly. However, the whole quantity of raw materials used to make powder coatings is presently imported to fill the domestic needs. Moreover, it is well known that the waste powder coatings from the domestic industries are mostly incinerated. The method of destructing the waste powder coatings by fire causes VOC to be generated, and this results in some serious environmental problems such as air pollution and so on. Therefore, the effective and proper measure must be devised to reuse the waste powder coatings for the purpose of eliminating waste of resources and avoiding the outflow of foreign currency. This study aims to make the plan to recycle the waste powder coatings, and its conclusion is drawn as follows: First, it can be seen that the waste powder coatings with a weak electrostatic power restore gradually to the original state of electrostatic power through the process of fusion and retreatment. Second, it can be estimated that those coatings, with the use of the cyclon, can be removed by dividing a powder of particles less than 10㎛. Third, it can be ascertained that the possibility of reusing the waste powder coatings is proved when it is divided into particles by cyclon and a revolving screen after the process of fusion, rolling, crushing and pulverization.

부착단백질이 사람 치수세포의 부착 및 증식에 미치는 영향에 관한 연구

신영주,최호영,민병순,박상진,최기운 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

The purpose of this vitro study was to evaluate attachment and proliferation of human pulpal cells to the attachment glycoprotein-coated and non-coated culture dishes. Well known adhesive glycoproteins were used, such as type I collagen, type IV collagen, fibronectin, laminin, and vitronectin. Each adhesive glycoproteins applied onto the culture dishes. In this study, the protein coated and non-coated dishes were classified as each groups. Human pulpal cells cultured onto each culture dishes. After 90 minute, 4 hour and 24 hour incubation attached cells in each group were counted with hematocytometer for evaluation of the attachment of human pulpal cells. The configurations of attached human pulpal cells were done by SEM observation. The results as follows 1. After 90 minute incubation the score of attachment of human pulpal cells was best in laminin-coated group among groups. Then fibronectin, type IV collagen group were better, and allproteins were higher than control. 2. After 4 hour incubation the numbers of attachment of human pulpal cells were most in fibronectin coated group. 3. After 24 hour incubation all of adhesive glycoproteins showed high and similar attachment effect to human pulpal cells. 4. In SEM observation, fibronectin and type IV collagen groups showed well spreaded human pulpal cells, then laminin group was moderately spreaded, and vitronectin group was mildly spreaded as well as control group.