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        • SCOPUSSCIEKCI등재

          경추간판탈출증 환자에서 요추천자후에 발생한 급성 양하지마비 - 증례보고 -

          도재원,황선철,윤석만,배학근,이경석,윤일규,최순관,변박장,Doh, Jae-Won,Hwang, Sun-Chul,Yun, Suck-Man,Bae, Hack-Gun,Lee, Kyeong-Seok,Yun, Il-Gyu Yun,Choi, Soon-Kwan,Byun, Bark-Jang The Korean Neurosurgical Society 2001 Journal of Korean neurosurgical society Vol.30 No.8

          경추간판탈출증 환자에서 척수조술을 위해 요추천자를 시행한 후에 갑자기 양하지마비가 발생한 1례를 보고 한다. 척추종괴환자에서 요추천자후 합병증으로 나타나는 운동마비는 요추천자후 1~4일째에 서서히 오는 경우가 일반적이며, 수시간내에 급성으로 하지마비를 나타내는 경우는 매우 드물어 현재까지 6례 정도만 보고되고 있을뿐이며 그 원인질환은 대부분 척수종양이다. 경추간판탈출증 환자에서 척수조술을 위해 요추천자를 시행한 후에 갑자기 양하지마비가 발생한 임상보고례는 현재까지 없다. 이러한 합병증을 막기위해서는 척수장애증상을 보이는 경추간판탈출증 환자에게 척수조술대신에 자기공명촬을 시행함이 현명하리라 본다. 이러한 합병증이 올 수 있는 기전과 예방방법에 대해 고찰하다. The incidence of paraplegia following drain of cerebrospinal fluid(CSF) by lumbar puncure below a spinal block is rare, and most of them occurred in spinal tumor. We report a case of acute paraplegia following lumbar puncture for computed tomography myelography(CTM) in a 42-year-old man who sustained a cervical disc herniation. Four hours after lumbar puncture for CTM, sudden paraplegia was developed. After emergent anterior cervical discectomy and fusion with cervical plating, the patient recovered completely. To the authors' knowledge, this is the first case of spinal shock complicating lumbar puncture for routine myelography in a patient with cervical disc herniation. The prompt recognition of this unusual complication of lumbar puncture may lead to good clinical outcome. Instead of CTM requiring lumbar puncture, MRI should be considered as the initial diagnostic procedure in a patient of cervical disc herniation associated with myelopathy. We discuss the possible mechanisms of acute paraplegia following lumbar puncture with literature review.

        • SCOPUSSCIEKCI등재

          다중심성 다형성 교아세포종 1예

          도재원,변박장,이인수 대한신경외과학회 1984 Journal of Korean neurosurgical society Vol.13 No.2

          A 46 year-old male with drowsy mentality and left hemiparesis had been treated. Right carotid angiogram showed a mass effect on the posterior temporal region. Preoperative CT brain scan revealed two separated hypodense masses with ring enhancement on the each hemisphere. The right-sided mass was totally removed and there was no invasion into the ventricle and meninges. The histological diagnosis was a glioblastoma multiforme. The left-sided mass was followed with the repeatd CT scan, which showed the similar CT findings of a glioblastoma multiforme, and there was no evidence of commissural extension. The above findings were consistent with the criteria of multicentric tumor.

        • SCOPUSSCIEKCI등재
        • SCOPUSSCIEKCI등재

          외경동맥과 내경동맥에서 동시에 혈액공급받는 두피의 동정맥기형 : 증례 보고 Case Report

          도재원,배학근,이경석,윤일규,변박장,배원경 대한신경외과학회 1993 Journal of Korean neurosurgical society Vol.22 No.10

          We report a rare case of scalp AVM concurrent feeding from external carotid artery and internal carotid artery, namely, superficial temporal artery and ophthalmic artery. This 20-year old woman was seen because of serpiginous pulsatile mass in the frontal scalp, and the mass was enlarged during pregnancy. The case that feeding from the internal carotid artery branch is very rare. Angiography, MRI and MR angiography findings are presented.

        • SCOPUSSCIEKCI등재

          뇌혈관조영술시 재파열된 동맥류 2례 : 증례보고 Report of Two Cases

          도재원,윤이규,배학근,목진호,이경석,윤일규,변박장 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.11

          We report two cases of reruptured anterior communicating artery aneurysm during cerebral angiography in one aged 80years and the other aged 59years. Both patients had emergency angiography on Day 0, within 5 hours of the latest rupture. The prognosis was very poor. We stressed the importance of the time interval between the latest rupture and angiography.

        • SCOPUSSCIEKCI등재

          측두골에 발생한 양성 연골아세포종 1예

          도재원,이인수 대한신경외과학회 1982 Journal of Korean neurosurgical society Vol.11 No.3

          A 39 year-old male with swelling of the left temporal region, the left facial numbness, visual disturbance and slurred speech had been treated. Plain skull film showed an osteolytic bony defect in the left temporal squama with sclerotic margin. Left carotid angiogram showed a mass effect on the subtemporal region. CT scan revealed a well demarcated homogenous increased density of a snowman appearance in the left temporoparietal region. On operation, the temporal extradural highly vascularized mass was totally removed piecemeal, and another 6×5×5㎝ of grayish brown rubbery-hard mass which located in the temporal lobe parenchyme was removed en bloc. The mass seemed to be extended from the extradural region. The histological diagnosis was a benign chondroblastoma. The patient was discharged without any evidence of neurological deficit.

        • KCI등재

          사람 血淸의 고양이 赤血球에 對한 凝集活性에 關한 硏究

          都在元 大韓法醫學會 1991 대한법의학회지 Vol.15 No.1

          For the purpose of new classification of human blood type, the author experimented the agglutination activities of human sera (donor; 137 persons) to blood cells(RBC). After investigating the relationships with the known blood types to compare each other, the following results were obtained: 1. Human sera could be classified into two groups by their agglutination activities to cat RBC; one was agglutination group and the other was no-agglutination group. 2. Of the 137 donors, the incidence of the former (agglutination group) was 46% and the latter was 54%. 3. Individual differences of cat RBC didn't effect on their agglutination reaction by human sera. 4. There was no significant relation between agglutination property of human sera to cat RBC and known blood types, such as AB0, C1, H, Vp, ab. C, CCI and other serum types classified by use of other animal RBC.

        • 뇌 고충증 : 증례보고 Case Report

          이경석,이인수,배학근,윤일규,이규,도재원 순천향대학교 1991 논문집 Vol.14 No.2

          고충증은 주로 피하 연조직과 표재 근막을 침범하는 기생충질환으로, 중추신경계를 침범하는 경우는 매우 드물다. 임상적으로는 뇌종양이나 만성 뇌종양과 유사하며 치료는 기생충을 수술로 적출해야 한다. 저자는 57세 남자에서 발생한 뇌 고충증 1례를 치험하여 문헌고찰과 함께 보고한다. Sparganosis is a parasitic infection, most commonly, involving subcutaneous soft tissue and superficial muscle fascia of the human body. Sparganosis of the central nervous system is rare. The worm present clinically as a mass suspicious for neoplasm or chronic abscess cavity. Surgical removal is invariable curative. We report a case of cerebral sparganosis occuring in 57-year-old man. Related literature are briefly reviewed.

        • Paraquat 투여로 인한 흰쥐 폐장변화에 대한 면역 조직화학적 연구

          도재원,김의한,강상균 순천향대학교 1992 논문집 Vol.15 No.2

          Paraquat에 의해서 유발되는 간질 및 폐포내 섬유조직 증식증의 진행과정을 알아보기 위하여 20마리의 흰쥐를 대상으로 10mg/kg, 20mg/kg를 복강내 주사하고 3일, 5일, 7일, 10일, 15일 간격으로 폐장을 적출하여 조직학적 및 면역조직 화학적 방법을 통해 관찰하여 다음과 같은 결론을 얻었다. 1. 10mg/kg를 투여한 군에서는 뚜렷한 손상을 보이지 않고 7일후에는 거의 정상으로 나타나 Paraquat에 의한 독성 효과는 투여된 양에 의존됨을 알 수 있었다. 2. 나타나는 폐장의 변화는 2단계로 분류될수 있는데 폐포내에 출혈, 부종 및 초자막 형성은 초기에 나타나는 병변이었으며, 간질 및 폐포내 섬유 조직 증식증은 후기에 나타나는 병변으로 일반적인 급성 호흡곤란 증후군때 보이는 소견과 비슷하였다. 3. 관찰 초기부터 폐포세포 Ⅱ형의 증식이 나타나는 것으로 보아 중독 초기에 이미 폐포세포 Ⅰ형에 손상이 나타남을 알 수 있었다. 4. 간질 및 폐포내 간엽조직은 시간이 경과됨에 따라 Vimentin에 강하게 염색되는 것을 볼 수 있는데 이는 간질 및 폐포내 섬유조직 증식증이 시간 경과에 따라 진행되고 있음을 의미한다. 5. 7일 이후에 상피세포가 다시 EMA에 강한 양성 반응을 보였으며 이는 이들 세포들이 재생되고 있음을 뜻하고 있으나 더욱 시간을 두고 관찰 할 필요가 있다고 본다. To investigate the progress of the Paraquat-induced pulminary interstitial and intralveolar fibrosis, 10 white rats were administered 10mg/kg and 10 white rats were administered 20mg/kg of Paraquat intraperitoneally. Three, five, seven, ten and fifteen days after this injection, the rats were sacrificed. The removed lungs were evaluated by immunohistological and histological study, so following results were obtained. 1. Toxic effects of Paraquat seem to depend on the dose of administrated Paraquat since the groups of rats treated with 10mg/kg revealed no significant tissue damage after 7 days. 2. The pulmonary changes by Paraquat can be classified into two stages : the early change such as hemorrhage, edema and hyaline membrane formation, and the late change characterized by interstitial and intra-alveolar fibrosis. These changes are similar to the findings observed in acute respiratory distrees syndrome. 3. Proliferation of Type Ⅱ alveolar cell at the time of the initial observation (3days) suggested that the damage of type Ⅰ alveolar cell had been occured prior to observation. 4. Strong Vimentin positive staining of the interstitial and intra-alveolar mesenchymal cell with time indicated the progression of the interstitial and intra-alveolar fibrosis. 5. Strong positive reaction of epithelial cells to EMA after 7 days of Paraquat adminstration indicated the regeneration of these cells. However, due to short duration of observation, it was hard to obtain conclusion whether this regeneration completed or not.

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