자궁내막암의 방사선치료 성적

김재성,김준상,조문준,박승호,노흥태,남상륜 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

Purpose : To evaluate survival rate, treatment failure pattern and complication of endometrial carcinoma patients treated with radiation therapy Materials and Methods : From November 1989 through March 1995, twenty two patients with endometrial carcinoma were treated with radiation therapy at Chungnam National University Hospital. According to the 1988 FIGO staging system, four patients had stage I A disease, 6 stage I B, 4 stage I C, 1 stage Ⅱ A, 6 stage Ⅲ A, and 1 stage Ⅲ B. Radiation therapy was given preoperatively to 2 patients, postoperatively to 19 patients, and curatively to one patient considered to be inoperable due to valvular heart disease. Twelve patients were treated with external radiation therapy alone by conventional technique (180-200 cGy/fraction), and 6 patients with external radiotherapy plus high dose rate intracavitary radiotherapy (HDR ICR), and 4 patients with HDR ICR alone. Results : All patients were followed up for 9 to 71 months (median 21 months). The overall 5 year survival rate of all patients was 68.9%. The 5 year survival rates of stage I , Ⅱ , and Ⅲ were 87.5%, 100%, and 41.6%, respectively. Relapse rate was 9.1% (2/22), and treatment failure occurred as a distant metastasis only without local failure. Early mild complication rate was 31.8% (7/22), and late complication rate 9.1% (2/22), including one radiation colitis and one vulvar ulcer. Conclusion : Adjuvant pelvic radiation thereapy is an effective local treatment modality to prevent local relapse in patients with endometrial carcinoma not accompanying severe late complications.

급성 및 만성 간질환에서 C형 간염바이러스 항체(anti-HCV)양성률

김삼용,성자원,김병호,이기천,허승식,길준영,정현용,이헌영,김영건 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

The prevalence of antibody against hepatitis C virus (anti-HCV) was investigated in 331 patients with various liver diseases from April 1992 to September 1992. The presence of anti-HCV was detected by Lucky HCD EIA test in 331 cases and by (Ortho HCV Antibody ELISA test 148 patients) The results are summarized as follows: 1. Overall, antibody to HCV(anti-HCV) was positive in 37(11%) of 331 patients with various liver diseases. 2. 16(11%) of 144 patients with chronic hepatitis, 2(5%) of 37 patients with alcoholic liver disease, 17(22%) of 76 patients with liver cirrhosis and 2(5%) of 38 HBsAg carriers were positive for anti-HCV.None of 12 patients with acute hepatitis, 11 patients with drug induced hepatitis and 13 patients with hepatocellular carcinoma was anti-HCV positive. 3. HBsAg positivity in patients who had anti-HCV was 24%(9/37). 4. A positive correlation was found between Lucky HCD and Ortho HCV test. Of 128 Lucky HCD negative cases, 124 cases were negative for Ortho HCV ELISA and 4 cases were positive for Ortho HCV ELISA Of 20 Lucky HCD positive cases, 11 cases were positive for Ortho HCV ELISA and 9 cases were negative for Ortho HCV ELISA. These results suggest that hepatitis C virus has an important etiologic role in HBsAg negative chronic hepatitis and liver cirrhosis in Korea. The diagnostic value of Lucky HCD EIA test may be slightly better or equivalent to Ortho HCV ELISA test in the diagnosis of Hepatitis C virus infection.

심초음파로 결정된 응급 심낭천자술의 천자부위

김성환,황성오,이강현,조준휘,강구현,문중범,이승환,윤정한,최경훈,김영식 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: The aim of this study was to determine whether the conventional subcostal approach is suitable for emergency pericardiocentesis in patients with cardiac tamponade or impending cardiac tamponade. Methods: This study was a prospective, observational study conducted at the emergency department of a tertiary hospital, Patients who had symptomatic pericardial effusion and who needed emergency pericardiocentesis in the emergency department were included in this study. We measured the epicardium-to-pericardium distance at the subcostal, parasternal, and apical area with two-dimensional echocardiography to determine the appropriate puncture site for pericardiocentesis. An epicardium-to-pericardium distance of more than 1.0 cm was considered as the primary safety factor in determining the Puncture site for pericardiocentesis. The skin-to-pericardium distance was considered as secondary safety factor. Results: Ninety-five consecutive patients(55 males and 40 females; total mean age: 53 year old) with cardiac tamponade or impending cardiac tamponade were enrolled in this study. The puncture site for pericardiocentesis, as determined by echocardiography, was the subcostal area in 43 patients(45%), the apical area in 40 patients(42%), the left parasternal area In 11 patients(12%), and the right parastemal area in one patient(1%). Pericardiocentesis failed in 2 patients(2%) with the subcostal approach and in one patient(1%) with the apical approach. The average epicardium-to-pericardium distance was 31 ±21 mm in patients with the subcostal approach and 21±8 mm in patients with other approaches. There were no differences in the amount of pericardial fluid and in the intraperical pressure among patient groups according to puncture site. There were two procedure related complications: a puncture of the right ventricle with the subcostal approach and a ventricular tachycardia with the apical approach.

MPLS 네트워크의 레이블 할당 정책 비교 및 시뮬레이션 방법 연구

장성식 ; 김용준 김천대학교 1999 김천대학교 논문집 Vol.20 No.-

A IETF working group proposed the MPLS technology that performs high speed switching using a dedicate hardware because increasing Internet Services require gast transmission of various types of traffic. MPLS utilizes the bandwidth of physical links maximally and supplies QoS, scalability and traffic engineering easily. Because this technology, however, was not standardized yet, various policies have been presented. In this paper, we compared existing.

장애인 엘리트체육의 실태 분석

최승권,이인경,문준혁,임찬규,한동기,김권일 한국특수체육학회 2005 한국특수체육학회지 Vol.13 No.1

The purposes of this study are to analyze actual status of elite sports for athletes with disabilities through investigating factors such as athletes constitutions, levels of game performance, and administrative and supporting organizations, which are critical bases for establishing the policy of elite sports for athletes with disabilities. The contents and scopes are as followings. First, analyzing composition of elite athletes with disabilities and current status of sports associations/federations. Second, analyzing the levels of game performance of elite sports for athletes with disabilities(Far East and South Pacific Games for the disabled, and Paralympics). Third, analyzing the support system such as administrative organization and support for athletes, leadership training, and financial support. Forth, analyzing survey on attitude and needs for elite sports of athletes with disabilities. Literature reviews, site visits, and survey were used to analyze the current status of elite sports for athletes with disabilities in Korea. The following outcomes were driven. First, this study revealed fewer numbers of sports federations, unbalanced composition of athletes in events, sex, and ages, and aging compared to international events and games. Second, this study revealed low performance level in team sports overall, and international competitive abilities but shooting, weight lifting, and archery were shown to be low. Third, this study revealed the weak establishment of administrative and financial supporting system.

골수염의 진단에 있어서의 Tc-99m Hexamethylpropylene amine oxime 백혈구 스캔의 임상적 유용성

최상호,김양수,정준원,정진원,추은주,서동대,배인규,양승오,우준희,류지소 대한화학요법학회 2001 대한화학요법학회지 Vol.19 No.1

배경 : 골수염의 진단에 있어 Technetium-99m을 이용한 삼상 골스캔(Tc-99m MDP스캔)은 단순방사선 검사상 정상소견을 보이는 경우에 쓰이는 1차적 검사로 매우 높은 민감도를 보인다. 그러나 Tc-99m MDP 스캔은 골절이나, 정형외과적 삽입물, 신경병적 관절병변과 같이 뼈의 재형성이 증가되는 상황에서도 양성소견을 보여 특이도가 낮은 단점이 있다. 이러한 단점을 보완하고자 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 유용성을 알아보고자 하였다. 대상 및 방법 : 골수염이 의심되어 Tc-99m HMPAO 백혈구 스캔을 시행했던 15명의 의무기록을 후향적으로 분석하였다. 골수염의 확진은 임상관찰 소견과 배양검사 결과와 병리소견을 기준으로 하였다. 결과 : 골수염의 진단에 있어 Tc-99m HMPAO 백혈구 스캔의 민감도와 특이도는 각각 100%와 78%였고 Tc-99m HMPAO 스캔의 경우는 100%와 18%였다. 가장 흔한 원인균은 methicillin-resistant S. aureus였다. Tc-99m MDP 스캔에서 양성소견을 보였던 환자중 3명의 환자가 Tc-99m HMPAO 백혈구 스캔에서 음성 소견을 보였으며 이 환자들은 추적관찰상 골수염이 없는 것으로 확인되었다. 결론 : Tc-99m HMPAO 백혈구 스캔은 골수염의 존재를 진단하는데 있어 민감도와 특이도가 높으며, 특히 뼈의 재형성이 증가되어 Tc-99m MDP 스캔의 특이도가 낮게 나타나는 상황에서 유용하리라 사료된다. Background Three phase bone scintigraphy, performed with technetium-labeled diphosphonates (Tc-99m MDP scan), is the very sensitive radionuclide procedure of choice for diagnosing osteomyelitis. But, Tc-99m MDP scan is less specific when bone remodeling is increased. To overcome this limitation, we evaluated the diagnostic value of technetium-99m hexamethylpropyleneamine oxime (HMPAO) labeled leukocyte scan in osteomyelitis. Methods : We retrospectively reviewed 15 patients with suspected osteomyelitis who performed Tc-99m HMPAO labeled leukocyte scan. The diagnosis of osteomyelitis was based on clinical course and bacterial culture, and pathologic findings. Results The sensitivity and specificity of Tc-99m HMPAO leukocyte scan was 100% and 78%, and those of Tc-99m MDP scan was 100% and 18%, respectively. The most common organism was Methicilein-Resistant S. aureus. Among the patients that showed persistent accumulation on Tc-99m MDP scan, three patients showed no uptake on Tc-99m HMPAO leukocyte scan and these patients were confirmed that had no osteomyelitis. Conclusion : Tc-99m HMPAO leukocyte scan is a useful test for determining the presence or absence of osteomyelitis, especially under condition that bone remodelin is increased.

이중혈류유발 심폐소생술이 심정지를 유발한 개의 단기 생존율에 미치는 영향

황성오,조준휘,강구현,김성환,문중범,이강현,이승환,윤정한,최경훈,홍은석 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background and Objectives: We previously reported that, compared with standard cardiopulmonary resuscitation(S-CPR), better hemodynamic effects could be achieved by simultaneous sterno-thoracic cardiopulmonary resuscitation(SST-CPR) in which we compressed the sternum and constricted the thorax circumferentially during the systolic period by using a device. This study was designed to assess whether SST-CPR, compared with S-CPR, improve the survival rate of dogs with cardiac arrest. Subjects and methods: Twenty-five mongrel dogs(19∼31㎏) were enrolled in this study. After four minutes of ventricular fibrillation induced by an AC current, animals were randomized to resuscitate with either S-CPR(n=13) or SST-CPR(n=12). Epinephrine(1 ㎎) was injected into the right atrium every three minutes after the beginning of CPR. Defibrillation was attempted after 6 minutes of CPR. Standard advanced cardiac life support was started if defibrillation was not successful. Results: SST-CPR resulted in significantly(p<0.001) higher systolic arterial pressure(91±47 vs 47±24 ㎜ Hg), diastolic pressure(43±24 vs 17±10 ㎜ Hg), coronary perfusion pressure(35±25 vs 13±9㎜ Hg), and end tidal CO2 tension(9±4 vs 3±2 ㎜ Hg). Two of 13 animals(15 %) resuscitated with S-CPR and six of 12 animals(50%) resuscitated with SST-CPR survived until 12 hours after cardiac arrest(p<0.05). Donclusion: SST-CPR, compared with S-CPR, improves the short-term survival rate in canine cardiac arrest.

농업인 평생학습체계 구축을 위한 농업인교육 발전방안 연구

정철영,송병국,김진모,문택석,허영준,주대진,최수정,한승완 한국농업교육학회 2008 농업교육과 인적자원개발 Vol.40 No.2

이 연구의 목적은 우리나라 농업인의 평생학습체계 구축을 위한 농촌진흥기관의 역할을 정립하고, 한국농업대학의 농업인대학 운영 본부화 방안을 수립하는데 있다. 이를 위해 관련 문헌고찰, 농업인 및 농촌진흥기관의 농업인 교육 담당자들의 인식 및 요구분석, 전문가 자문 및 협의회 등의 방법을 활용하였으며, 이를 토대로 도출된 연구의 결과를 제시하면 다음과 같다. 첫째, 농촌진흥기관의 농업인교육관련 연계를 위해서는 한국농업대학이 농업인평생교육기관으로 평가인정을 받고, 전국의 농업인대학을 총체적으로 지원하는 역할을 수행하는 것이 바람직하다. 이때 지역의 농업기술센터는 한국농업대학과 협력적 관계를 구축하여 학점은행제 운영에 소요되는 교육 및 이력관리를 지원하는 역할을 수행하는 것이 필요하다. 둘째, 한국농업대학의 농업인대학 운영본부화를 위하여 평생학습원의 조직이 추가되는 것이 바람직하다. 이에 따라 평생학습원의 비전, 미션 및 전략이 제시되었으며, 조직의 기능 및 세부과제가 제시되었다. 셋째, 농업인교육의 학점은행제를 도입을 위한 체계를 설정한 후, 농업관련 기존 표준교육과정 분석, 농업인 요구분석, 전국 농업인대학 교육과정 분석, 기존 농업관련 전공 교육과정 분석, 전문가 검토 등의 과정을 거쳐서 '영농 전문학사'와 '농업 경영 학사'의 표준교육과정을 개발하였다. 넷째, 고졸미만 농업인을 위한 사전학습제도화를 위하여 농업인교육의 평가인정을 통한 방안과 One-Stop 평생학습모델을 통한 방안을 제시하였다. The purposes of this research were to assign the role of rural development organizations, and to establish the strategy for the making headquarter of farmer's university. The study was performed as follows: (1) analyzing the related literatures, documents, records review, (2) need analysis of farmers and members ig rural development organizations in terms of farmer's lifelong learning, (3) consulting experts. The following four findings are the results of this study: (1) Korean national agricultural college should be headquarter of farmer's universities and be approve for lifelong learning credit. Also, agricultural technology & extension centers should run educational program for the lifelong learning credit. (2) For the doing role of headquarter of farmer's university, division of lifelong learning should be add to department of technology training in Korea agricultural college. In relation with this, vision, mission and strategy of division of lifelong learning were suggested. (3) Steps for introduction of credit bank system of farmer education were suggested. Also standard curriculums of 'farming associate degree' and 'agricultural management bachelor's degree' were developed through analyzing existing standard curriculum related with agriculture, analyzing need of farmer, analyzing curriculum of farmer's university, analyzing curriculum of agriculture major. (4) For farmer who do not have high school graduate, two solutions were suggested which are approving farmer's education and one-stop lifelong learning model.

흰쥐의 발치와에 이식한 단계별 치아싹의 발육 과정

정희훈,정한성,김성오,최형준,이제호,최병재 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

The purpose of this study is to evaluate at which stage of tooth germ would develop into normal calcification and hence to increase the success rate of transplantation. Therefore, tooth germs on the 15th, 17th embryonic day and the 3rd day of birth were separated for allotransplantation into maxilla of adult rat of 11 weeks. Calcification processes were analyzed radiographically and histopathologically at 4 weeks and 8 weeks after allotransplantation. The results are as follows: 1. Allotransplanted tooth germ at 4 weeks and 8 weeks showed delayed calcification compared to that of normal odontogenesis. 2. At 4 weeks, abnormal calcified tissue, such as odontoma and ankylosis of osteodentin with surrounding alveolar bone were observed. 3. At 8 weeks, allotransplanted tooth germs of the 15th and 17th embryonic day showed calcification and osteodentin surrounded by periodontal ligament. 4. At 8 weeks, allotransplanted tooth germs of the 3rd day of birth showed calcification composed of cementum and osteodentin. In this study, we observed small sized and amorphous calcified tissue from allotropic allotransplantation of tooth germs. Since these calcified tissue were underdeveloped and shaped irregularly, for calcification into normal tooth form, further study needs consideration about the reduction of surgical trauma, developmental stage of transplanted tooth germ, blood supply from recipient site, fixation method in transplanted site and period of transplantation. 외상이나 치주 질환,유전적 결함 등에 의하여 치아가 상실되었을 경우,보철 수복이나 임플란트로 치료하고 있다. 그러나 보철 수복이나 임플란트는 자연치가 아닌 인공치를 이용한 치료로서 기능성과 섬미성 등에서 자연치에 비하여 한계 가 있으므로 자연치를 이용한 이식 방법에 관심이 증가하고 있으며 치아 이식의 성공률을 높이기 위한 이식 치아의 발육과 성장에 대한 연구가 진행 중이다. 이 연구는 세 가지 단계의 치아싹을 발치와에 동종 이식하고 치아싹이 발육하여 석회화가 이루어지는지 평가하기 위하여 임선 15일과 17일,출생 후 3일 된 흰쥐의 치아싹을 분리하여 11주 된 흰쥐의 발치와에 이식하고 4주와 8주 후 방사 선학적 그리고 병리조직학적으로 석회화 과정을 관찰하여 다음과 같은 결과를 얻었다. 1. 발치와에 이식된 임신 15일과 17일,출생 후 3일 된 치아싹에서 4주와 8주 후 석회화된 조직이 형성되었다. 2. 임신 15일과 17일,출생 후 3일 된 치아싹을 발치와에 이식하고 4주 후 치아종 같은 비정상적인 석회화 조직과 인접 치조골과 유착된 골양상아질이 관찰되었다. 3. 임신 15일과 17일 된 치아싹을 발치와에 이식하고 8주 후 골양상아질이 보였으며 치주인대로 둘러싸인 것도 관찰되었다. 4. 출생 후 3일 된 치아싹을 발치와에 이식하고 8주 후 골양상아질과 백악질이 형성되었다. 이 연구는 치아싹을 흰쥐의 발치와에 이식한 후 치아싹의 발육을 관찰한 것으로 이식 조직에서 크기가 작고 무정형의 석회화 조직이 형성되었다. 정상적인 치아보다 형태가 불규칙하고 발육이 늦었으므로 이식된 치아싹이 정상적인 치아 형태로 석회화되도록 하기 위해서는 이식 조직의 발육 정도와 이식 조직을 절제할 때 외과적 손상의 감소,치아싹으로의 풍부한 혈류 공급,이삭 기간,이식 조직의 고정을 고려하여 더 많은 연구가 필요할 것으로 생각된다.

운동선수의 임장불안에 대한 연구

홍관이,이광재,김두경,부기원,노성규,한상준,박기동,오수일,문병용,이철규,박장평,엄기진,박남환 江原大學校附設 體育科學硏究所 1984 江原大學校附設體育科學硏究所論文集 Vol.- No.9

This study is designed to grasp the elements and situations of stage fright in order to propose a part of ways to cope with it. We make 511 top-class high school players, male and female, in the central districts (Seoul, Inchon, Kyungki, Chungbuk, and Kangweon Province) on object of questionnaire, and get the following results. Through players generally have all-round characters they show weakness in the superiority and emotional stability while showing strength in the sonformity. This fact comes to be related to the elements which cause stage fright. Physiological changes also have many effects on the symptom of stage fright. Especially, stage fright increases when players show sensitive reaction to the self-consciousness of final consequence which comes from the tension or uneasiness of sympathetic nerve, Thus, it turns out that players make use of reducing psychological burden by physical exercise or adjusting the level of demanded result in order to release the stage fright.