Enhanced Densification and Hardness of Titanium Bodies Sintered by Advanced Hydrogen Sintering Process

Jung‑Min Oh,Ja‑Geon Koo,Jae‑Won Lim 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.6

A new sintering technique for enhancing a densification and hardness of sintered titanium body by supplying hydrogen wasdeveloped (Hydrogen Sintering Process, HSP). The HSP was developed by only injecting hydrogen into an argon atmosphereduring the core time. As a result, sound titanium sintered bodies with high density and hardness were obtained by the HSP. In addition, a pore size and number of the HSP specimens were smaller than those of the argon atmosphere specimen. It wasfound that the injecting hydrogen into the argon atmosphere by HSP can prevent the formation of oxide layers, resulting inenhanced densification and hardness.

人工甘味料의 合成過程에 對한 再考

박숙자,안송자,유영자,윤정자,윤종은,이명재,정규영,황민자 梨花女子大學校 藥學硏究所 1963 梨花藥學硏究 Vol.- No.4

16주간의 자전춤 참여가 중년비만고혈압여성의 관상동맥위험인자에 미치는 영향

곽정자(Kwak Jung-Ja),김종경(Kim Jong-Kyung),최현민(Choi Hyun-Min),노호성(Nho Ho-Sung) 한국체육과학회 2008 한국체육과학회지 Vol.17 No.2

It is generally known that cardiovascular and metabolic diseases such as hypertension, diabetes, hyperlipidemia increase morbidity and mortality in postmenopausal women. This study investigated the effects of Jajun-Dance to coronary heart disease of middle age women with hypertension. Thirteen sedentary women (55.8±5.2 yrs) were recruited for this study, and completed 16 weeks of Jajun-Dance program. All subjects were diagnosed as essential hypertension patients. Blood-sugar level (FBG), total cholesterol (TC), triglyceride (TG), systolic blood pressure (SBP), diastolic blood pressure (DBP) and visceral fat area (VFA) were measured. The Jajun-Dance program included 10 minutes warm up (exercise for flexibility), 40 minutes Jajun-Dance, and 10 minutes cool down. The subjects participated in Jajun-Dance program three times a week. Exercise was maintained at exercise intensity corresponding to rating of perceived exertion (RPE) 13-15. The results showed that FBG, SBP, and DBP (6.0 ㎜Hg) were significantly decreased after Jajun-Dance program. TG and VFA tended to decrease, but there were no significant differences. This study suggests that hypertensive middle-aged women could modify coronary risk factors with regular exercise, and that the aerobic Jajun-Dance program could effectively reduce high blood pressure.

대장직장 종양에 대한 내시경 점막하 절제술의 연대순 임상 결과와 학습 곡선

이상민 ( Sang Min Lee ),김은수 ( Eun Soo Kim ),박경식 ( Kyung Sik Park ),조광범 ( Kwang Bum Cho ),김동춘 ( Dong Choon Kim ),강유진 ( Yu Jin Kang ),이유진 ( Yoo Jin Lee ),이정민 ( Jung Min Lee ),최은성 ( Eun Sung Choi ),최재혁 ( Ja 대한소화기학회 2014 대한소화기학회지 Vol.64 No.4

Background/Aims: Endoscopic submucosal dissection (ESD) is an effective procedure for en-bloc curative resection of the colorectal tumor. As it requires high technical skills and experience in therapeutic endoscopy, it is important to understand learning curve of ESD technique. The aim of this study was to retrospectively describe the clinical results of ESD and to evaluate learning curve for the ESD of colorectal tumors. Methods: A total of 90 patients with 90 colorectal neoplasms, who had undergone ESD at a tertiary referral hospital from July 2009 to December 2012, were enrolled. The ESD was performed by a single endoscopist. All ESD cases were divided into three periods: first, cases 1-30; second, cases 31-60; and third, cases 61-90. Results: The en-bloc resection rates in third period (100%) was significantly higher than that of the first (93.3%) and second period (80%) (p=0.025). The perforation rate in third period (0%) also significantly decreased compared with that of the first (13.3%) and second period (20%) (p=0.032). To calibrate the difference of tumor size among periods, proficiency was calculated, as the procedure time per specimen area (min/cm2). The proficiency in third period (4.3) was significantly shorter than that of the first (16.8) and second period (10.2) (p=0.004). Conclusions: The learning curve of colorectal ESD in our study shows that at least 60 cases of ESD have to be conducted to acquire sufficient skill of degree without perforation. (Korean J Gastroenterol 2014;64:198-205)

벤조디아제핀 수용체 영상용 양전자 방출 핵종 표지 플루마제닐 유도체 [F-18](3-(2-Fluoro)flumazenil의 합성과 생체 내 분포

장영수,이숙자,강삼식,홍성현,이명철,이동수,정준기,정재민,조정혁 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.6

Purpose: Radiotracers that bind to the central benzodiazepine receptor are useful for the investigation of various neurological and psychiatric diseases. [C-11]Flumazenil, a benzodiazepine antagonist, is the most widely used radioligand for central benzodiazepine receptor imaging by PET. We synthesized 3-(2-[F- 18]fluoro)flumazenil, a new fluorine-18 (t1/2=110 min) labeled analogue of benzodiazepine receptor imaging agent, and evaluated in vivo for biodistribution in mice. Materials and Methods: Flumazenil (Ro 15-1788) was synthesized by a modification of the reported method. Precursor of 3-(2-[F-18]fluoro)flumazenil, the tosylated flumazenil derivative was prepared by the tosylation of the ethyl ester by ditosylethane. [F-18] labeling of tosyl substitued flumazenil precursor was performed by adding F-18 ion at 85℃ in the hot cell for 20 min. The reaction mixture was trapped by C18 cartridge, washed with 10% ethanol, and eluted by 40% ethanol. Bidistribution in mice was determined after intravenous injection Results: The total chemical yield of tosylated flumazenil derivative was ∼40%. The efficiency of labeling 3-(2-[F-18]fluoro)flumazenil was 66% with a total synthesis time of 50 min. Brain uptakes of 3-(2-[F-18]fluoro)flumazenil at 10, 30, 60 min after injection, were 2.5±0.37, 2.2±0.26, 2.1±0.11 and blood activities were 3.7±0.43, 3.3±0.07, 3.3±0.09%ID/g, respectively. Conclusion: We synthesized a tosylated flumazenil derivative which was successfully labeled with no-carrier-added F-18 by nucleophilic substitution.

직접 검화법을 이용한 조제분유의 콜레스테롤 분석법 개발

김진만,박정민,윤태형,임동길,윤창용,정자영,정인식,곽병만,안장혁,Kim, Jin-Man,Park, Jung-Min,Yoon, Tae-Hyung,Leem, Dong-Gil,Yoon, Chang-Yong,Jeong, Ja-Young,Jeong, In-Seek,Kwak, Byung-Man,Ahn, Jang-Hyuk 한국축산식품학회 2011 한국축산식품학회지 Vol.31 No.6

본 연구에서는 조제분유 중의 콜레스테롤을 신속하고 정확하게 분석하기 위해 지방 추출 과정을 거치지 않는 직접 검화 방법을 선택하여 분석법 개발을 시도하였다. 조제분유 분말시료를 직접 검화 수기에 취하여 검화 온도, 검화 시간, KOH 농도의 3가지 인자에 대해 콜레스테롤 회수율이 가장 양호하게 나타나는 최적 검화조건을 확립하고, 검화 후 수세과정에서 액액 분배가 용이한 용매 조건도 확립하였다. 또한 콜레스테롤 피크의 완전한 분리를 위한 적정 기기 조건을 확립하였다. 그 결과, 시료 약 2 g에 16 M-KOH 10 mL를 넣고 $90^{\circ}C$에서 60분 가열하여 검화한 후 diethyl ether로 3회 추출하고 hexane을 최종시험용액으로 하여 기기분석을 했을 때의 회수율이 98.80%로서 가장 양호하게 나타났다. 본 연구를 통해 개발된 조제분유의 효율적인 액액분배 및 직접가열 검화법은 일원배치 분산법에 의해 유화가공식품의 콜레스테롤 분석법으로 유효성이 검증되었으며, 아울러 개발된 전처리 방법 및 기기 분석 조건을 활용해 다양한 분석 기관에서 신속 정확하고 효율적인 콜레스테롤 분석을 수행할 수 있을 것으로 기대된다. 또한 산업체의 품질관리 및 검증기관에서 필요시 모니터링에 적극 활용 가능할 것으로 사료되며, 이를 통해 유화가공식품 류의 함량표시 및 규격관리의 정확성과 효율성 증대에 기여하여 제조업체의 정확하고도 효과적인 품질 및 안전성 확보에 기여할 수 있을 것으로 판단된다. 특히 위해 물질에 대한 정확한 함량 판단이 중요한 조제분유 등의 영 유아용 식품의 안전성 확보에 지대한 공헌을 할 수 있을 것으로 기대된다. An improved cholesterol analysis method was developed for powdered infant formula by gas chromatographic separation after liquid-liquid extraction and partition. In the official Korea Food Standard method for cholesterol analysis, the water phase and solvent phase were not well separated in the case of emulsified foods such as powdered infant formulas and baby foods. For the rapid and simple sample preparation method, an optimized direct saponification condition was established for heating temperature, heating time, and KOH concentration. From the results, the optimum conditions were as follows: heating temperature $90^{\circ}C$, heating time 60 min, and 16 M KOH 10 mL for a 2 g infant formula sample; improved separation condition for gas chromatography was as follows: the initial oven condition was $250^{\circ}C$ for 25 min, the oven temperature was increased to $290^{\circ}C$ by $10^{\circ}C$/min ratio, and finally the oven temperature remained at $290^{\circ}C$for 9 min. The developed method could be implemented for the study of cholesterol, providing the advantages of reduced inspection time and cost in emulsified foods such as infant formula.

크론병에 대한 CoPPLX의 방어효과에 대한 연구

이호학,김유림,문창기,이재일,양병윤,김종수,이정민,정재혁,안석진,박상준,김윤권,김소연,김영중,조민구,최영자,장성조 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

가족복지사업에서의 자원봉사 프로그램의 실천방안

정민자,김명희 울산대학교 2001 생활과학논문집 Vol.3 No.1

본 연구의 목적은 현재 가족복지사업에 대한 개념을 살펴보고, 가족복지사업의 방향과 아동, 노인, 장애인, 여성을 대상으로 실행되고 있는 가정복지 현황을 진단하고자 한다. 현재 실시되고 있는 다양한 자원봉사프로그램을 정리해 보고, 우리가 가족복지사업으로 실행할 수 있는 프로그램을 살펴보고자 한다. 또한 교육프로그램에 대한 자원봉사자의 요구와 교육현황을 살펴보고, 앞으로 가족복지사업에 참여하는 자원봉사자를 위한 교육프로그램 방향과 실천방안을 논의하고자 한다. 본 연구에서는 다음을 강조하고 있다. 건강한 가족을 유지하기 위한 이론의 정립과 연구가 실천 분야와 접목하여야 하며, 가족 중심의 가족복지법의 제정 또는 사회복지서비스법이 강화되어야 한다. 재가중심 가족복지사업의 실행과 전문인력확보와 교육프로그램이 개발되어야 한다. 자원봉사자들의 활동영역에 따라 교육프로그랭이 실행되어야 하며, 가족단위의 가족자원붕사활동이 이루어져야하며, 가족의 중요성을 인지하여야 한다. This research focuses on the theory and practice of famity welfare. First, we reviewed the awns of the family welfare program and the current delivery of services for children, the old, the disabled and women. Second we researched and designed practical programs for family welfare services. Third, we reviewed and redesigned the existing volunteer training programs with the help of volunteers imports. Forth, we reviewed the theory and practice of existing welfare laws. We conclude that either; A new family welfare law and practice must be developed and enacted with the family as the nucleus or the existing social welfare law must be strengthened.

한국 전통 떡류에 대한 대학생들의 인지도 및 기호도에 관한 연구

정효선,신민자 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

The purpose of this study was to investigate the perception and preference of the college student about Korean traditional rice cakes. Self admistered questionnaires were collected from 512 college students in Seoul, Kyungki, Chungchungdo, Kungsangdo, Junlado and Gangwondo area. Data was analysed by t-test, one-way ANOVA and correlation. The recognition of Korean traditional rice cake was generally low except for the items that could be easily seen as either seasonable or festive foods. There was a significant difference in the average score of recognition and preference for each kinds of Korean traditional rice cake according to the major, gender of subjects. Baiksulgi, Injulmi, Yaksik, bindaedu, Songpyun and Garaeduk are highly prefered Korean traditional rice cakes when as Gaepiduk, Ssookiulpyun, Kongchalduk and Garaeduk are poorly among college students.

配偶者選擇 決定에 미치는 要因 및 重要度에 관한 硏究

정민자 울산대학교 1987 연구논문집 Vol.18 No.1

본 연구의 목적은 배우자 선택이 관련되는 요인들과 배우자 선택시의 조건의 중요도를 알아보고자 하였다. 배우자 선택에 관한 연구가 가족학의 기초분야임에도 불구하고 실제 미약한 상태이다. 특히 한국에서는 실제 조사뿐만 아니라 이론 연구도 제대로 진행되지 못하고 있다. 본 연구는 외국에서 논의되고 있는 이론적 관점들을 크게 사회교환적 모델과 여과론적 모델을 중심으로 구조화 시켜 보았으며, 실제 현상 파악의 기초를 제공하고자 관련요인들을 전반적으로 조사 분석하였다. 그 결과 배우자 선택 현상에서 한국 가족의 정통성이 많이 사라지고 개인주의적으로 진행되고 있었다. 특히 현대 배우자 선택 현상은 내적 특성인 사랑, 건강, 성격, 가치 생활력 등이 중요시 되고있음을 알수 있었다. The purpose of this study is to investigate the importance and the factors influencing mate selection. Theories of mate selection are explained two viewpoints: social exchange model and filter model. The date, collected from 275 the married living Ulsan, is analyzed by statistical methods, such as frequency distribution and X2-test. The Major findings as follows; 1) General factors correlated mate selection; (1) The types of mate selection are love marriage(40.7%), arranged match(25.8%) and lovearranged match(33.5%) (2) The periods of decision making for mate selection are 6months 1year(31.7%) and within 3 months(24.9%) The period of engagement is within 3 months(49.6%). (3) The horoscopic date is less important today. But females are more interesting in it than male significantly. (4) The discrepancy in age is 3-4year. (5) The ratio of premarital sex experience with her(his) partner is 23.6%. 2) Inner factors correlated mate selection; (1) The married were supported by parents and friends on selection and decision making. (2) A favorable impression and attraction influences upon mate selection. Especially personalty attraction and value similarity is important. (3) Love(affection) and sexuality is necessary, but premarital sex needs not to marry. (4) Generally they are openhearted meeting their partners. 3) The importance of mate selection conditions was ordered. The sequences as follows; (1) health, (2) personality, (3) love, (4) living ability, (5) value orientation, (6) a bright future, (7) virginity, (8) growth environment, (9) occupation, (10) education level, (11) approval of parents 4) Subjects offered their opinions to young people. Their opinions as follows; (1) personality, (2) humanity, (3) love, (4) health, (5) living ability, (6) growth environment (7) a bright future must be considered well. Through this study, I can result that the phenomenon of mate selection in changing Korean family has become individualistic. In morden mate selection, internal traits(love, personality, health, value, living ability etc.) is important especially.