Smart Cell Array Chip Fabrication using Functional Microbeads containing Optical Codes for Self‐identification

Joo?Myung Ahn,Joong Hyun Kim,Ji Hoon Kim,Man Bock Gu 한국생물공학회 2010 한국생물공학회 학술대회 Vol.2010 No.10

현훈 환자 Neuron Specific Enolase의 임상적 의의

김원주,김선곤,유철형,김원찬,김용덕,최영철,이명식 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

두경부 마사지가 중환자실 환자의 수면과 불안에 미치는 효과

김미용,전선영,송윤희,최은진,김재희,김미성,주명순,김남선 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: This study was to apply head and neck massage to patients in intensive care unit and to inventigate the effect of that massage on sleep and state anxiety. Method: The subjects in this study were 27 patients who were admitted in medical intensive care unit. The study was performed from June thru September of 2005 on the One-group pretest-posttest design and the sleep, state anxiety of the subjects were measured before and after head and neck massage. For data analysis, paired t-test and Pearson correlation coefficient were utilized. Result: The first hypothesis that the subjects might have a better sleep after being exposed to head and neck massage was accepted. The second hypothesis that the subjects might feel less state anxiety afrer being exposed to head and neck massage was accepted. The third hypothesis that the sleep of the ICU patients maight be correlated to their anxiety was accepted, as there appeared correlation between their sleep and anxiety. Conclusion: Head and neck massage is identified as one of independent nursing interwentions to improve the sleep of ICU patients and ease their anxiety, and it is necessary to apply it to clinical practices.

국내의 양식산 무지개송어 성어로부터 분리된 IHNV의 G protein gene에 대한 연구

김기홍,김위식,김춘섭,김영진,정태성,신이치, 키타무라,정성주,오명주 한국어병학회 2003 한국어병학회지 Vol.16 No.3

An Infectious hematopoietic necrosis virus strain (IHNV-RTK) was isolated from cultured rainbow trout at Kumi in Korea during 2000 and 2001. In the RT-PCR amplification with the specific primer set designed from IHNV G protein region, a 540 bp PCR product was amplified from the RTK strain. The RTK strain showed higher sequence homology with the published IHNV G protein genes (RB-76, LR-73, Col-85, and Carson-89).

양식산 터봇, Scophthalmus maximus에서의 Irido-like virus 감염

김위식,김기홍,김춘섭,김영진,정성주,정태성,신이치, 키타무라,마모루, 요시미즈,오명주 한국어병학회 2003 한국어병학회지 Vol.16 No.3

본 연구는 병리조직학적 및 전자현미경적 방법을 통해 양식산 turbot에서 발생하는 irido-like virus의 감염증을 소개하고자 한 것이다. 2003년 6월 전북 고창 소재 육상수조에서 양식중인 turbot치어에서 50∼70%의 대량폐사가 발생하였다. 병어는 사료섭취가 저하되고 힘없이 유영하다 폐사되었으며, 죽기 직전의 어류는 복부가 팽만되고 안구가 돌출되며 체색이 옅어지는 증상을 보였다. 해부학적 조사 결과, 아가미 빈혈과 간이 퇴색되어 있었으며, 특히 비장조직이 심하게 비대되어 있었다. 병어에 대한 조직학적 검사에서 비대 세포를 특징으로 하는 특이 병변이 주로 신장과 비장의 조혈조직에서 관찰되었으며, 아가미, 심장, 위, 장, 간, 췌장, 지방 조직에서도 관찰되었다. 그리고 전자현미경적 관찰 결과, 비대 세포의 세포질내에서 육각형의 지름이 136∼159 ㎚인 Irido-like virus를 관찰할 수 있었다. The high mortality of cultured juvenile turbot, Scophthalmus maximus occurred in Gochang on June, 2003. The diseased fish was lethargic with reduced feed intake. Grossly, these fish showed pale body, abdominal extension and exophthalmia. The dominant internal gross features of diseased fish were severely enlarged spleen, pale gills and or liver. Diseased fish histologically showed basophilic enlarged cells in the kidney, spleen, gill, heart, stomach, intestine, liver, pancreas and adipose tissue. Transmission electron microscopy (TEM) reveled hexagonal virions in the cytoplasm of necrotic cells. The viral particles lead a central electron-dense core and an electron translucent zone, and were 136-159 nm in diameter. These results suggest that the virus belonging to the iridoviridae was responsible for the mortality of cultured juvenile turbot.

인문학의 새로운 이상, 자유와 평등을 넘어 사랑으로: 인문학 주체로서 여성의 역할

김명주 ( Myung Joo Kim ) 충남대학교 인문과학연구소 2012 인문학연구 Vol.39 No.1

최근까지 인문학 담론은 자유와 평등이라는 이상을 준거로 비판담론을 펼쳐왔다. 그러나 자유와 평등은 인간이 서로 분리되고, 독립적이며, 자율적 존재라는 전제하에 가능하며, 인간이 실상 서로 깊이 관계되고 상호보완적 존재하는 현실에서 볼 때 더 이상 적절한 이상이 될 수 없다고 본 논문은 주장한다. 따라서 본 논문은 새로운 이상으로서 사랑을 제안하면서, 사랑담론은 자유와 평등 담론의 한계와 단점을 보완하고, 개인과 세계와의 합일을 목표로 하면서 참된 인간실현의 가능성을 제시한다고 주장한다. 기존의 담론을 사랑담론으로 전환하는 과정에서 인문학의 주체로서 점점 증가추세에 있는 여성들은 그들 특유의 여성성--인류의 초기부터 여성의 모성과 사회적 억압에서 비롯되는 부드러움, 유연함, 민감성, 공감능력, 객관성, 관계하고 중개하는 능력--으로 인하여 담론의 전환기에 풍성한 역할을 기대할 수 있다고 제안한다. 단, 여성성은 생물학적 여성만의 전유물이 아니라, 생물학적 남성과 여성에게 공히 나타날 수 있는, 기술적 특질임을 강조하고, 또한 남성보다는 여성에게 여성성이 더욱 두드러진 특질이기 때문에 여성의 역할을 기대할 수 있다고 주장한다. Beyond Freedom and Equality toward Love as a New Ideal with Women`s Increasing Role in Humanities Kim, Myung-Joo This paper argues that the studies in the humanities have been preoccupied with freedom and equality as ideals for their criticism until recently, but they are not proper ideals not only because they are inaccessible but also because their premises about human existence-separate, independent, and autonomous individuals-do not fit into the reality that human beings are profoundly connected and interdependent. So this paper suggests that love could be a new ideal which humanities discourses are concerned with because love complements the defects of discourses on freedom and equality and opens up a possibility for a new world in which human beings are fully realized mainly by being one with the others and the world. In such transition from the old to the new ideal, it is also argued that the increasing number of women in the humanities could contribute to its acceleration and completion with their unique femininity-gentleness, flexibility, sensitiveness, compassion, objectivity, ability to mediate and relate--which has been developed through women`s long care for babies and oppression. However, femininity should not be confused with biological women in that femininity, residing both in men and women, is only a descriptive category not a prescriptive one.

급성 심근경색 초기에 도플러 심초음파를 이용한 좌심실 이완기 기능의 평가

신원용,김주성,김철현,이광희,최태명,현민수,김성구,권영주 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

Background : Congestive heart failure after acute myocardial infarction relate to left ventricular systolic sysfunction. Also, left ventricular diastolic function contribute to heart failure. The aims of this study were, firstly to characterize left ventricular diastolic function by transmitral flow velocity, and secondly to study the significance of Doppler measurements in relation to the development of heart failure in the early phase of myocardial infarction. Method : Pulsed Doppler echocardiography of transmitral flow was assessed in 34 patients with acute myocardial infarction. According to the Doppler transmitral flwo velocity profile, the study patients were assigned to the three groups: normal filling pattern (DT > 140ms, IVRT < 100ms), relaxation abnormality (DT > 140ms, IVRT ≥ 100ms), pseudonormal or restrictive pattern (DT ≤ 140ms). Also, on the basis of the presence of heart failure during first week of hospitalization, the patients were divided into two groups: patients with no sign of heart failure (Killip class Ⅰ) and heart failure (Killip class Ⅱ-Ⅳ). Results : Of the 34 patients studied, 10(29%) were normal filling pattern, 17(50%) abnormal relaxation and 7(21%) were restrictive patterns. The left ventricular ejection fraction(EF, 40 ±6%) of restrictive pattern was significantly lower than that of normal filling pattern of abnormal relaxation(p < 0.01). And, the IVRT, DT, E/A and left ventricular EF were reduced in patients with heart failure(14 patients) compared to no sign of heart failure(20 patients)(p<0.05). Of the patients with heart failure, IVRT and left ventricular EF were reduced in patients with DT≤140 ms compared to DT> 140ms(p=0.001). Conclusion : Left ventricular diastolic dysfunction is present early after onset of symptoms of acute myocardial infarction. Assessment of left ventricular diastolic function complements measurements of systolic function in the evaluation of cardiac function. DT, IVRT, E/A and left ventricular EF are useful predictors for development of congestive heart failure following acute myocardial infarction.

사립체 DNA 뉴클레오타이드 3243 A→G 돌연변이 [MTTL1^*MELAS3243G]에 의한 MELAS 증후군

박기형,김승현,이영주,김희태,김주한,김명호,박성섭 대한신경과학회 1998 대한신경과학회지 Vol.16 No.4

한국인 직무 스트레스 측정도구의 개발 및 표준화

장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4

Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.

삽접법을 이용한 기계접목 메카니즘 연구

김주엽,이기명,박규식 慶北大學校農業科學技術硏究所 1997 慶北大農學誌 Vol.15 No.-

과채류의 재배에 있어서 접목은 작물의 안정적인 생산과 품질 향상을 위해 없어서는 안되는 기술이다. 그러나 지속적인 숙련 노동력의 감소와 농촌 인구 노령화 등으로 나타나는 노동력 부족 현상은 접목묘의 대량생산 공급에 어려움이 되고 있다. 본 연구에서는 기계접목에 있어서 접목법이 간단하며 접합부자재가 불필요한 삽접법을 이용하는 기계접목 메카니즘 개발의 기초연구를 수행하였다. 트레이상의 육묘상태에서 자동으로 접목하기 위한 기계접목의 기초연구로써 1본씩 수동 공급하는 반자동 기계삽접의 메카니즘 개발에 관한 연구로서 얻어진 결과를 요약하면 다음과 같다. 1. 접합부자재를 사용하지 않고 대부분 과채류에 적용가능한 삽접 기계접목장치의 메카니즘을 구성하였다. 2. 오이를 접수로 하고 신토좌와 흑종을 대목으로 하는 기계접목시험에서 모두 98%의 접목성공율을 나타냈다. 3. 1본 수동 공급에 의한 기계접목 시스템을 10초 정도로 접목 성능은 저조하지만 기계접목 메카니즘의 가능성을 확인하였다. Grafting is an important skill for the stable supply and production of high quality. However, the shortage of skillful labor has become great difficulty for a mass production of grafting-seedling. In this study, a suitable mechanism for a grafting machine was developed. The following summarize the results of this study: 1. An insertion method was selected for mechanism of the grafting machine without bonding agent, clip, pin. This insertion-grafting method can be applicable to general vegetables and a mass production system. In addition to, this method is suitable for developing the grafting mechanism. 2. Growing point was removed while remaining both cotyledons on rootstock. The productivity of this system was five fold greater than the one of an experienced labor. 3. The rootstock processing was placed on left and scion processing unit was placed on right of the system, then processed rootstock and scion graft by rotating 180˚. 4. The efficiency tests on mechanical grafting rate showed 98%.