In vivo study for the hemostatic efficacy and foreign body reaction of a new powder-type polysaccharide hemostatic agent

Yoonhyeong Byun,Eun Jin Kim,Areum Lee,Young-Ah Suh,Hee Ju Sohn,Jung Min Lee,Jae Seung Kang,Yoo Jin Choi,Youngmin Han,Hongbeom Kim,Wooil Kwon,Jin-Young Jang 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.102 No.2

Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote the hemostatic cascade and those that physically form a barrier by absorbing blood. The latter, powder-type hemostatic agents have the advantages of being inexpensive and more absorbable with less foreign body reactions (FBRs) and are applicable to a relatively wide area. This study was conducted to verify the safety and efficacy of a newly invented polysaccharide product (OOZFIX, Theracion Biomedical), which improves blood absorption and hemostatic effects. Methods: Two separate animal experiments were performed. The first evaluated FBRs histologically at 3 days, 2 weeks, and 4 weeks, after implantation of OOZFIX in rats, and the second compared hemostatic performance of OOZFIX and Arista AH (Bard) in the porcine liver punch biopsy model. Results: We found minimal FBRs in the 3-day group and no reactions in both the 2-week and 4-week groups after implantation of hemostatic agents. The time to hemostasis of OOZFIX was not significantly different from that of Arista AH (median [interquartile range]: 9 [6–10] minutes vs. 8 [6–10] minutes, respectively; P = 0.522). When comparing the serial bleeding grade tendency, there was no statistical difference between OOZFIX and Arista AH (P = 0.656). Conclusion: OOZFIX caused a minimal FBR that disappeared within 2 weeks in vivo, and its hemostatic performance was comparable with that of an existing agent, Arista AH. Further clinical studies are required in the future.

Serum Antioxidative Vitamins Levels and Dietary Habits in Korean Stomach Cancer Patients

Choi,Min-Ah,Kim,Byung-Sick,Yu,Rina 한국영양학회 1998 Journal of Nutrition and Health Vol.31 No.4

인천 인현동 호프집 화재 피해자 분석

최정태,안무업,안희철,최영미,정재봉,서정열,유기철,이삼우,박석현,조준휘,김성환,김아진,송근정 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4

Purpose : This study was conducted to develop field triage, transportation, distribution, and prehospital care at a fire disaster by analyzing the victims of the fore that broke out at a bar in Incheon. Method : We analyzed the cases of the victims of a fire in Incheon in Oct. 1999. We determined the primary care hospital, the arrival time, the burn size, the outcome, and the injury type from the medical records, the concerned organ records, and interviews with concerned persons. Result : The total number of victims was 137: 56 prehospital deaths, 1 hospital death, and 80 survivals. The Pearson correlation coefficient between the burn size and the severity was -0.175. There were 121(89.6%) cases of inhalation injury, 59 (43.7%) cases of flame burns, 66 (48.9%) cases of hypoxic brain damage, and 16 (11.9%) cases involving other types of injury. Conclusion : The causes of death of the fire victims were inhalation injury and hypoxic brain damage due to CO poisoning and other toxic inhalants. We propose the use of a simple triage and rapid treatment(START) system and a reassessment the delayed category in fire disasters.

청량리 부흥주택의 특성 및 변화에 관한 연구

정아선,최장순,최찬환 대한건축학회 2004 대한건축학회논문집 Vol.20 No.1

This study is focused on the characteristics and changes of Cheongnyangni public housing which is one type of row housing area in 1950's and also accomplished by site survey and examination. Cheongnyangni public housing block contains the conditions of the times what is called the solution of housing shortage and rehabilitation of korean war which to be a pressing social problem in 1950's. It is formed in consequence of social and cultural factors of those days and constantly changed in urban structure. Also it is read the features of transition following to the period as an initial row housing in 1950's which is one stage of our housing history by means of interchanging the transforming process of housing block structure, street system, lot, plan and etc.

FR-III를 이용한 3급 부정교합 환자의 치험례

곽아람,박재홍,최성철,김광철 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.2

반대교합은 교두간섭이나 유구치의 조기상설 등에 의해 하악이 기능적인 전방위로 위치된 기능성 반대교합과 하악골의 과성장,상악골의 열성장 또는 양자가 복합된 골격성 반대교합,구치부의 관계는 1급이나 전치부의 치축경사가 조화를 이루지 못해 발생되는 치성 반대교합으로 분류된다. 1970년 Rölf Fränkel에 의해 소개된 Functional regulator(FR)의 한 종류인 FR-III는 상악의 열성장을 동반한 반대교협을 개선하기 위해 유치열기,혼합치열기,및 초기 영구치열기에 사용되고 있다. 이 장치는 비정상적인 근육력을 차단하여 구강내 치열 및 악궁에 대한 힘의 불균형 상태를 개선하고,구강주위의 근육을 훈련시켜 새로 형성된 힘의 균형에 의해 이차적으로 악안면골의 크기와 형태를 변화시킨다. 본 증례는 상악 중절치가 맹출하기 전에 미약한 상악 열성장과 전치부의 깊은 교합을 동반한 전치부 반대교합을 FR-III로 치료하여 양호한 결과를 얻었기에 이에 보고하는 바이다. In children with Class III malocclusion, it is important to identify whether the etiology is functional, dental, skeletal. FR-III developed by Rölf Fränkel in 1970, has been used during deciduous, mixed, and early permanent dentition to correct class III malocclusion characterized by maxillary skeletal retrusion. According Frankel, the vestibular shields and upper labial pads act to counteract the forces of the sur rounding musculature that restrict forward maxillary development and cause a retrusion in maxillary tooth position. This can achieve favorable developments with the basal bone. teeth and alveolar bone. We report FR-III that can be applicated in cases of early mixed dentition with mild maxillary deficiency and deepbite before the eruption of permanent maxillary incisor.

전치부의 경미한 공간부조화 개선을 위한 가철성 장치의 적용 예

곽아람,최영철,박재홍,최성철,김광철 大韓小兒齒科學會 2007 大韓小兒齒科學會誌 Vol.34 No.4

골격성 부조화가 없는 I급 부정교합은 치아-악궁 간의 크기 차이에 의한 총생(crowding)이나 공극(spacing)이 주된 문제점이다. 이와 같은 경미한 공간 부조화를 개선시키고자 할 때,치열의 종류,치아-악궁크기 부조화의 양,환자의 협조도,또는 환자의 요구 등에 따라 치료 방법은 다양할 수 있다. 본 증례보고에서는 I급 구치부 관계를 지니면서 전치부의 치아-악궁크기 부조화의 양이 크지 않은 영구치열에서 상하 악 전치부의 경미한 총생이나 공극이 관찰되는 경우에 사용할 수 있는 clear aligner와 spring aligner 장치의 이용에 관하여 보고하고자 한다. 이와 같은 장치들의 임상 적용에는 몇 가지 제한적인 조건이 있기는 하지만,잘 선택된 증례에서는 매우 유용하며 편리하게 이용될 수 있다. 특히 총생이 존재하는 경우에는 이를 해소시킬 공간이 치열 내에서 확보되어야 하므로,확실한 분석과 진단으로 치아 인접면 삭제의 양을 정확히 결정하여 각 치아들의 근심면과 원심면에서의 삭제의 양이 균등히 이루어질 수 있도록 하는 것이 바람직하다. 또한 치간에 공극이 존재하는 경우에는 배열 후 치열궁 둘레의 감소와 함께 상하악 전치부 간의 over-jet 문제가 생길 수 있어 대합치열과의 교합관계에 신중을 기하여야 한다. Class I malocclusion without skeletal problem results from tooth size/arch-size discrepancies, either evidenced by crowding, or spacing problems. Treatment method can be chosen according to dentition, the amount of arch discrepancy, patient compliance, or patient demands. We report of clear aligner and spring aligner that can be applicated in cases of permanent dentition with minimal arch discrepancy in anterior segment. There are some limits of application, but these are very useful appliances in the selective case. When crowding exists, definitive analysis and diagnosis should be made before starting treatment because certain amount of space must be obtained somewhere in the dentition to resolve the crowding. Therefore, appliance should be applied when lacking space is small. Also, in cases with spacing arch circumference is reduced after alignment so no problem in intermaxilla occlusal relationship must be confirmed. In case with crowding, judicious removal of interproximal enamel is indicated.

한국비서자격시험의 개선점과 비교연구

남자현,이미정,이미영,이아영,정해금,최유정,이미숙,전인선,정혜림 이화여자대학교 법정대학 비서학과 1997 비서학연구 Vol.- No.17

임부의 연령에 따른 보완대체요법에 관한 인식 태도 경험 비교 연구

김연진,김지연,노경민,신혜리,유예지,이지민,장희조,정아인,최소정,강숙정,이향연,민혜영 이화여자대학교 간호과학대학 2016 이화간호학회지 Vol.- No.50

Purpose: This study aims to test if the age of pregnant women affects the perception, experience, and attitude towards complementary alternative therapy (CAT), by investigating the perception, experience, and attitude of pregnant women under the age of 35, and above 35 (Advanced Maternal Age). The study will 1) find the general characteristics of pregnant women under and over the age of 35 2) compare the perception, behavior, and experience of pregnant women under and over the age of 35, and 3) find the comparison of the perception, behavior, and experience according to the general characteristics of pregnant women under and over the age of 35. Method: The subjects of this study are composed of 44 women under the age of 35 and 44 women above the age of 35, totaling 88 pregnant women visiting midwiferies, obstetrics and gynecology, and baby fairs in Seoul and Gyeong-Gi area. Data for this study was collected from November 28, 2015 to January 6, 2016 for 40 days. The collected data analyzed mean, standard deviation, t test, ANOVA, and chi-square by using SPSS 23.0. Result Results show that there is a significant difference in the perception, attitude, and experience of the two-sample groups in the use of CAT. The question of “what is most necessary when applying CAT in a hospital clinical environment” for the perception criteria came out with the results of t=9.980, p<.05. For the attitude, results showed that the answers of pregnant women under the age of 35 displayed a more positive attitude towards CAT. (t=2.421, p<.05) Lastly, in the experience section, pregnant women under the age of 35 showed more CAT use than the other sample group. Conclusion Results have shown that there is a difference in the perception, behavior, and experience between the two sample groups. Therefore further research on the efficacy and the adverse effects of CAT needs to be done.

요양급여 적정성 평가체계 혁신 중장기 계획

김상지,전숙경,이창원,정영애,안재영,안유미,권아영,임상희,최정남,윤미선,변의형,조미현 건강보험심사평가원 2021 HIRA RESEARCH Vol.1 No.2

[PA-0071] Identification of QTLs Conferring Flavanol Contents in Soybean Seeds

Jae Ah Choi(Jae Ah Choi),Sewon Park(Sewon Park),Hyun-Ju Jang(Hyun-Ju Jang),Moon Young Kim(Moon Young Kim),Suk-Ha Lee(Suk-Ha Lee) 한국육종학회 2022 한국육종학회 공동학술발표집 Vol.2022 No.-