한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

Floristic characteristics of vascular plants and first distributional report of Pseudostellaria baekdusanensis M. Kim in Yongneup wetland protected area

Young-Chul Kim,Hyun-Hee Chae,Sang-Heock Oh,Seung-Ho Choi2,Moon-Pyo Hong3,Gi-Heum Nam,Jae-Yoon Choi,Hyun-Sook Choi,Kyu-Song Lee 한국환경생태학회 2015 한국환경생태학회지 Vol.29 No.2

Yongneup wetland protected area, the only high moor in Korea, is a core area to conserve biodiversity. Even though the Yongneup wetland protected area is relatively small, various plant species are distributed in the Yongneup wetland protected area because it includes various habitats showing different environmental gradients. Vascular plants distributed in the Yongneup wetland protected area were identified as a total of 376 taxa that is composed of 73 families, 217 genera, 322 species, 3 subspecies, 44 varieties and 7 forms. For endangered plants designated by the Ministry of Environment, 5 species including Trientalis europaea var. arctica, Lilium dauricum, Halenia corniculata, Lychnis wilfordii and Menyanthes trifoliata were found and 34 taxa were confirmed to be distributed only in the mountainous wetland habitats. Regarding naturalized plants, a total of 11 taxa were distributed, but most of them were distributed in the areas where artificial interference has occurred. And in areas inside the wetlands that are relatively well preserved, 2 species of Bidens frondosa and Erigeron annuus were observed. In this study, the occurrence and distribution of Pseudostellaria baekdusanensis M. Kim, which was recently found in Mt. Baekdu and reported as a new species, were identified in the Yongneup wetland protected area. A wetland is a very vulnerable area to drastic environmental changes and damages to its ecosystem could cause the extinction of rare plant species which are distributed only in the wetlands. Therefore, it is mandatory that current status of the Yongneup wetland protected area is evaluated and actions to prevent rapid environmental changes are taken. Fourteen separate investigations were conducted in 2013 and another four in 2014, to evaluate current status of the Yongneup wetland protected area. These investigations have provided us the basic information for future actions of conservation and restoration.

複合 韓藥劑 淸籬滋坎湯의 抗癌效果 및 作用機轉 糾明

Cho, Kyung-Sam,Kim, Si-Young,Park, Jai-Kyung,Choi, Seung-Hoon,Chung, Se-Young,Yoon, Hwi-Joong 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Kyung Sam Cho¹Si Young Kim¹, Jai Kyung Park²,Seung Hoon Choi³,Se Young Chung⁴, Hwi Joong Yoon¹¹College of Medicine, ²East-West Medical Research Institute, ³College of Oriental Medicine, ⁴College of Pharmacology, Kyung Hee University,Seoul, Korea. The Anti-cancer Effect of Oriental Medicine Chung-Ri-Ja-Gam-Tang in the Mouse with Metastatic Lung Cancer. Proceedings of International Symposium on East-West Medicine, Seoul. 231-243, 1999.-The oriental medicine Chung-Ri-Ja-Gam-Tang is an herbal medicine which has been used for pulmonary diseases and known as having immune stimulatory effects. It has been known effective in lung cancer. So we studied the effects and the mechanisms of this herbal medicine it the mouse with metastatic lung cancer. The metastatic lung cancer of the mouse was produced with melnoma cell line(B16BL/6).5×10□/mouse tumor cells were injected intravenously to the CDF1 mouse via tail vein. The mice were divided 4 groups. The first group was treated with 50mg/kg extract of Chung-Ri-Ja-Gam-Tang per oral for 10 days after cancer cell injection, second group treated with saline after cancer cell injection, the third group with medicine without cancer cell, and the last group with saline only. After 10 days treatments some of the mice were scarificed and the lung and spleen was removed. The survival duration, weight change, the number of metastatic cancer nodule of the lung, the NK cell activity, the capacity of cytokines(INF-γ,INF-α,IL-2) production and the proliferation activities of mouse lymphocytes were measured. The surival times of the group 1 mice were longer and the weight loss was less than the group 2 significantly. The number of the metastatic nodule of the lung were decresed in the group 1 than the group 2. The production of INF-γ,was increase in group 2 than group 3 and 4, IL-2 production was increased in group 1 than group 2,3,4 significantly. There was no difference in TNF- α production and proliferation activity of lymphocyte in each group. The NK cell activity was significantly increased in group 1 than group 2,3,4. We conclude that the Chung-Ri-Ja-Gam-Tang has the effect of increasing the NK cell activity of the CDF1 mouse with metastatic lung cancer(B16BL/6). And it is suggested that the increased production of the IL-2 is the mechanisms of enhanced NK cell activity.

Pulse Power를 이용한 혐기성 소화 효율 증대

최한나,전용우,정윤진,홍승모 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

Anaerobic digestion is commonly used in wastewater treatment plants to stabilize sludge produced in primary and secondary treatment, to produce renewable energy as methane, and to reduce the volume of solids for ultimate disposal. Previous studies on anaerobic digestibility of primary and secondary sludge present that secondary sludge showed poor anaerobic digestibility and less gas production. The objectives of this research were to study the effects of pulse power pretreatment on anaerobic digestibility of waste activated sludge. These objectives were achieved through operation of carefully-controlled laboratory digesters under various conditions. The conclusion made from this study are as follows: 1) To maximize the efficiency of pulse power pretreatment for waste activated sludge, the optimum operation conditions for coaxial reactor with 7 rings are decided as follows; a) optimum pulse repetition rate : 110㎐, b)feeding service : once-through mode, c) optimum hydraulic retention time : 1.0-1.5sec 2) Pretreated WAS by pulse power system showed increase of SCOD, ECP, and V.A by 13.6, 4.6, and 7.1 times. 3) From the results from operation of lab scaled anaerobic digester, pulse power sludge pretreatment increased GPR from 0.39㎥gas/㎏VS_add · day to 0.66㎥gas/㎏VS_add · day and methane content from 43.9% to 87.9%. Thus, increase of methane production rate was increased by 3.4times. 4) During the steady state operation of anaerobic digester, the removal efficiency of TCOD and VS were improved by 44.6% and 31.5% respectively after pulse power pretreatment of waste activated sludge.

관광산업의 국가경제적 중요성(重要性) : 외래(外來)관광객 지출이 한국경제에 미치는 효과

윤석홍,최승회 한국항공대학교 2000 論文集 Vol.38 No.-

한국을 방문하는 외래(外來)관광객이 방문기간 동안 「음식 및 숙박업」 과 「운수 및 보관업」에 지출하는 비용이 한국경제의 각 산업부문에 걸쳐 유발(誘發)하는 생산효과와 부가가치(附加價値)효과를 산업연관분석(産業聯關分析 또는 投入産出分析) 방식으로 측정하였다. 측정결과 생산유발효과는 「음식점과 숙박업」의 경우 1.72904이고 「운수와 보관업」은 1.50705이며, 부가가치유발 효과는 각각 0.90382와 0.7304으로 나타났다. With the methods of Inter-Industrial Relation Analysis, both effects of the Domestic Products Inducement and Value Added Inducement when foreign tourist expending to 「foods, beverages, and accommodations」 and to 「transport and warehouse」 are calculated. It concludes that the Inducement coefficients of the former is 1.72904 and the latter is 1.50705, and their Value Additional coefficients are 0.90382 and 0.7304 respectively.

이화명충에 對한 "통일벼"의 耐蟲性 機作에 關한 硏究

李炯來,崔承允 서울大學校 農科大學 1977 서울대농학연구지 Vol.2 No.1

This study was conducted to evaluate the nature of the variety Tongil (Suweon 213-1) in resistance to the striped rice borer, Chilo suppressalis Walker, comparing with those of Rexoro (susceptible check) and TKM-6 (resistant check) selected at IRRI. 1. The striped rice borer moths much more preferred the variety Tongil for ovipositon than the Rexoro and TKM-6. The variety Tongil had more egg masses and more number of eggs than the varieties Rexoro and TKM-6, while the variety TKM-6 having more egg masses and more number of eggs than the variety Rexoro. This reaction was consistent throughout the test regardless of the number of tillers per hill. 2. In laboratory, preference of larvae for feeding was studied with 5cm of stem pieces of the varieties. The result showed, in contrast to the case of ovipositional preference, that the striped rice borer larvae least preferred the stems of the variety Tongil among the test varieties, while larvae much more preferred the stems of Rexoro than those of TKM-6. 3. The larval weights at 20 days later infested on the 40 day-old plants were the lowest on the variety Tongil among the test varieties. On the variety Rexoro the larvae had heavier body weights (43.0mg), higher pupation (64.9%) and higher adult emergence (83.3%) than those on the variety Tongil (larval weight 30.3mg, pupation 60. 9%, adult emergence 60.7%) and the variety TKM-6 (larval weight 35.7mg, pupation 56.3%, adult emergence 51.9%). The pupal weights, however, were not consistent among the test varieties and/or sexes in comparison with the larval weight, pupation and adult emergence above mentioned. 4. Field experiments ildicated that the incidence of dead hearts at 70 days after transplanting was relatively higher on the variety Tongil (11.1%) than those on the varieties Rexoro (8.9%) and TKM-6 (8.4%), and the incidence of white heads at harvest was in contrast to the dead hearts lower on Tongil (9.8%) than those on Rexoro (27.4%) and TKM-6(13.9%). At harvest lower larval observed on Tongil (49 larvae/40 hills) than those on the susceptible variety Rexoro (104 larvae/40 hills) and on the resistant variety TKM-6 (70 larvae/40 hills). The average larval weights collected from three test varieties at harvest were 80.5mg from Tongil, 83.7mg from TKM-6 and 99.6 mg from Rexoro. 5. Increased nitrogen fertilizer application to the variety Tongil, the striped rice borer damage was increased. Also, preferecne of larvae for feeding significantly increased with the increase of nitrogen fertilizer application. 6. Any specific association between the plant characters and striped rice borer resistance could not be found. The variety Tongil even having large number of tillers, short plant height, large stem, broad leaf, etc., had still high preference of months for oviposition, low preference of larvae for feeding, low damage, and relatively high antibiosis. 7. Resistance of the variety Tongil to the striped rice borers seemed to be associated with the low feeding preference and the relatively high antibiosis, not associated with the ovipositional preference.

나주지역 문화관광자원 활성화에 관한 연구

최윤홍,나승화 한국문화관광학회 2000 문화관광연구 Vol.2 No.1

The tourist trade of Naju city in its present condition shows Naju's lack of interest as a central tourist attraction since 1997. In 1998 the tourist rate began to increase because of the interest in Naju's historical temples and the Bannam's tombs. This indicates the growing concern for cultural assets and national treasures in this area. The purpose of this research is to develop Naju's cultural tourist trade and establish an image of Naju as a historical tourism city. The development of cultural tourism resources should produce on a commercial scale tangible cultural assets to improve the historical sites and increase the tourist trade as well as to preserve the historical areas. In order to fulfill these tasks, it is necessary to develop cultural resources and assets to maintain all historical areas such as fortress, pavilions, temples and tombs, and utilize local temples as spiritual, moral and cultural foundations.

쥐의 성주기에 따른 자궁 비만세포와 성호르몬의 변화

최영자,제갈승주,윤영승,김재만 木浦大學校 基礎科學硏究所 2001 基礎科學硏究誌 Vol.19 No.-

Mast cells reside in connective tissue and mucous tissue that encircle the internal environment of the body, where they mediate inflammatory response encountering foreign materials. Mast cells are also found in uterus tissue which is, in fact, exposed to external world. Because the cells are provoked by invading foreign cells to cause inflammatory response, their response in the uterus should be controled for success in fertilization and implantation, in that the foreign sperms and fertilized egg are willing to invade into the body. In order to confirm such assumption, we investigated the changes in mast cell numbers and their contents in the rat uterus during the estrus cycle and related these to the changes in sex-hormone concentration. The mean number of mast cell at the proestrus and estrus phase was 4.8±2.72 and 5.98±1.55. respectively. The number increased as much as 3 times more then previous phase at the metestrus phase and subsided to half at following the diestrus phase. Those mast cells were subdivided type. Connective tissue type was major at metestrus and diestrus phase. At the following proestrus, however, the muscous type was largely increased and major population was changed to muscous and intermediate type at estrus phase. In the immature uterus of young female, as few as 1.67±0.23 cells were detected and most of them were mucous and intermediate type. The concentration of circulating estradiol-17 β was lowest at the metestrus phase both in free and bound form. The results suggest that estrogen may be involved in inhibiting swarming of mast cells in the uterus and accumulating the contents of secretory vesicles.

참깨에서 추출한 Sesamin 섭취가 혈청 지질 농도에 미치는 영향

윤명호,신준한,김한수,탁승제,최병일 아주대학교 1997 아주의학 Vol.2 No.2

Objectives : High serum cholesterol is one of the major risk factors of coronary artery disease. We investigated the lipid-towering property and the side effects of sesamin, an unsaturated fatty add extracted from sesame oil, for the primary prevention of coronary artery disease. Methods : The 37 patients (20 mates and 17 females) with hyperlipidemia, ages ranging from 22 years to 70 years old (48±12), who did not have atherosderotic diseases except essential hypertension were given three capsules of sesamin once daily for 6 weeks. The lipid profile of the patients were examined before and after sesamin treatment, and the patients were grouped according to the presence or abscence of hypertension, smoking habit and obesity. Result : Compared with pretreatment, the total cholesterol level of sesamin treated group decreased significantly (254.2±29.6 versus 241.6 34.0 ㎎/dl, p< 0.05). The level of LDL-cholesterol (162.6±24.3 versus 156.6±32.8 ㎎/dl)HDL- cholesterol (47.5±10.0 versus 47.0±8.7 ㎎/dl) and triglyceride (196.5±95.4 versus 179.3±96.7 ㎎/dl) and the ratio of LDL/HDL- cholesterol (3.6±0.9 versus 3.4±0.9) were not significantly different. The effect of cholesterol lowering property of sesamin was predominant in hypertensive, non- smoking and obese group (P< 0.05 vs pretreatment). The laboratory tests including complete blood cell counts, serum transaminases, total protein, albumin, blood urea nitrogen, creatinine and blood glucose did not change significantly. Conclusion : The lipid lowering effect of sesamin was statistically significant on the total cholesterol particularly with obese, non-smoking and hypertensive patients. There was no significant side effect during sesamin administration. Therefore, three capsules of sesamin as a single daily dose were effective in lowering total cholesterol and safe to administer in patients with hyperlipidemia.

뇌동맥류성 지주막하 출혈에 대한 Nimodipine의 치료 효과

이승윤,최창화 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.4