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甘豆湯 전탕액과 구성약물이 배양심근세포 박동수에 미치는 영향
박준배,권강범,황인진,김우경,김희찬,오광수,이호섭,류도곤 대한동의병리학회 2001 동의생리병리학회지 Vol.15 No.4
To test the protective effect of herbal medicine on myocardial damage against adriamycin-induced myocardiotoxicity, cytotoxicity of adriamycin was examined using MTT assay and protective effect of herbal medicine in the presence of water extract of Gamdu-tang, Gamigamdu-tang, or single constituents of these prescriptions was examined using counting of beating rate. The results of these experiments were obtained as follows : Adriamycin resulted in a decrease in viability and beating rate in cultured myocardial cells. Gamdu-tang water extract shows effects of protection from the cardiocyte toxicityinduced by adriamycin treatment such as increases beating rate. Gamigamdu-tang water extract shows the similar protective evvect as shown in gamdu-tang treatment on the decreasing of beating rate induced by adriamycin. Radix Glycyrrhizae, Semen Glycine, and Folium Phyllostachyos water extract shows a significant effect of protection for cardiotoxicity induced by adriamycin in cultured myocardial cells. These results show that adriamycin elicits toxic effects in cultured myocardial cells derived from neonatal mouse, and suggest teat water extract of gamdu-tang, gamigamdu-tang, Radix Glycyrrhizae, Semen Glycine, or Folium Phyllostachyos is very effective in the prevention of adriamycin-induced cardiotoxicity/
서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)
김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1
In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.
장세진,고상백,강동묵,김성아,강명근,이철갑,정진주,조정진,손미아,채창호,김정원,김정일,김형수,노상철,박재범,우종민,김수영,김정연,하미나,박정선,이경용,김형렬,공정옥,김인아,김정수,박준호,현숙정,손동국 大韓産業醫學會 2005 대한직업환경의학회지 Vol.17 No.4
Background and Purposes: Over the past three decades, numerous studies performed in Korea have reported that job stress is a determinant risk factor for chronic diseases and work disability. Every society has its own culture and occupational climate particular to their organizations, and hence experiences different occupational stress. An occupational stress measurement tool therefore needs to be developed to estimate it objectively. The purpose of this study is to develop and standardize the Korean Occupational Stress Scale (KOSS) which is considered to be unique and specific occupational stressors in Korean employees. Subjects and Methods: Data were obtained from the National Study for Development and Standardization of Occupational Stress (NSDSOS Project: 2002-2004). A total of 12,631 employees from a nationwide sample proportional to the Korean Standard Industrial Classification and the Korean Standard Occupational Classification were administered. The KOSS was developed for 2 years (2002-2004). In the first year, we collected 255 items from the most popular job stress measurement tools such as JCQ, ERI, NIOSH and OSI, and 44 items derived from the a qualitative study (depth interview). Forty-three items of KOSS, in the second year, were retained for use in the final version of the KOSS by using Delphi and factor analysis. Items were scored using conventional 1-2-3-4 Likert scores for the response categories. Results: We developed eight subscales by using factor analysis and validation process: physical environment (3 items), job demand (8 items), insufficient job control (5 items), interpersonal conflict (4 items), job insecurity (6 items), organizational system (7 items), lack of reward (6 items), and occupational climate (4 items). Together they explained 50.0% of total variance. Internal consistency alpha scores were ranged from 0.51 to 0.82. Twenty-four items of the short form of the KOSS (KOSS-SF) were also developed to estimate job stress in the work setting. Because the levels of the subscales of occupational stress were gender dependent, gender-specific standard norms for both the 43-item full version and the 24-item short form using a quartile for the subscales of KOSS were presented. Conclusion: The results of this study suggest that KOSS might be an appropriate measurement scale to estimate occupational stress of Korean employees. Further and more detailed study needs to be conducted to improve the validity of this scale.
Kang, Beom-Jun,Kim, Jeong-Hwan,Kim, Yooil The Society of Naval Architects of Korea 2016 International Journal of Naval Architecture and Oc Vol.8 No.6
Due to the uncertainties related to the flaw assessment parameters, such as flaw size, fracture toughness, loading spectrum and so on, the probability concept is preferred over deterministic one in flaw assessment. In this study, efforts have been made to develop the reliability based flaw assessment procedure which combines the flaw assessment procedure of BS7910 and first-and second-order reliability methods (FORM/SORM). Both crack length and depth of semi-elliptical surface crack at weld toe were handled as random variable whose probability distribution was defined as Gaussian with certain means and standard deviations. Then the limit state functions from static rupture and fatigue perspective were estimated using FORM and SORM in joint probability space of crack depth and length. The validity of predicted limit state functions were checked by comparing it with those obtained by Monte Carlo simulation. It was confirmed that the developed methodology worked perfectly in predicting the limit state functions without time-consuming Monte Carlo simulation.
Jun-Beom Song,Young-Seop Byun,Jeong Kim,Jae-Eun Song,Woo-Jin Song,Beom-Soo Kang 한국항공우주학회 2008 한국항공우주학회 학술발표회 논문집 Vol.- No.-
Unmanned Systems Design Lab of Pusan National University has been researching the coaxial rotorcraft-based UAV since 2005 which completed manufacturing and flying with commercial-off-the-shelf flight control computer at 2007, The development of the flight control computer has been progressed since 2007 with PC104 industrial computer with real-time operating system, A real-time operating system was applied in order to minimize modification effort for frequent change of an operating flight program and control algorithm during development phases, All components of hardware were integrated and tested for a flight data acquisition during 2007, It initially went through comprehensive tests with commercial-off-the-shelf single rotor radio control helicopter platform, The developed flight control computer will be implemented to the coaxial rotorcraft UAV after it is proven that the FCC has enough reliability from the single rotor platform, This paper proposes a systematic approach for development of a flight control system with intermediate product concept. Also, detailed development activities and trouble shootings during development processes are presented.
지방정부 정책채택과 확산기제의 영향요인 연구 - 갈등 예방 및 관리 등을 위한 조례채택을 중심으로 -
박범준 ( Beom Jun Park ),박형준 ( Hyung Jun Park ),강문희 ( Moon Hee Kang ) 한국정책학회 2016 韓國政策學會報 Vol.25 No.3
최근 우리나라의 갈등의 빈도 및 정도가 심화됨에 따라, 기초자치단체의 갈등의 체계적인 관리를 위한 갈등조례 채택비율이 매년 증가하고 있다. 하지만 지역별로 상이한 갈등조례의 내용과 그 효과성에 대해 연구자마다 다른 견해를 보이고 있다. 이러한 상황에 주목하여 본 연구에서는 기초자치단체의 갈등조례 채택을 정책혁신으로 정의하고 조례채택에 영향을 미치는 원인을 정책확산 이론에 기초하여 학습, 강제, 모방요인과 기초자치단체의 내부적 요인으로써 정치적, 사회적, 재정적 요인을 선정하여 분석하였다. 이를 위해 본 연구에서는 사건사분석(EHA)을 이용하였으며, 분석 기간 및 대상은 2007년부터 2015년까지 227개 기초자치단체이다. 분석결과, 정책확산 요인으로 강제과 모방요인이, 지방정부의 내부적 요인으로써 정치적 요인과 사회적 요인이 갈등조례 채택에 유의미한영향을 미치는 것으로 나타났다. 반면, 학습요인과 지역의 재정적 요인은 유의미한 영향을 미치지 못하는 것으로 분석되었다. 주목할 점은 본 연구에서 활용한 사회적 요인인 지역의 갈등빈도가 갈등조례 채택여부에 정(+)의 영향을 미쳤다는 점이다. 이는 지역의 수요를 반영한 조례 채택으로, 현재 지방정부의 갈등조례 채택에 있어 일정부분 합리성에 근거한 정책 선택이 이루어지고 있다고 볼 수 있다. Many local governments have been acting the conflict management ordinance to prevent conflict and reduce the social cost from conflict in local government since 2007, passing this conflict manangement bylaw in Chungbuk Province. We can find there are some difference when they pass this bylass and what contents they includeed in this ordinance. Many Korean scholars have studied policy adoption and iffusion in local government but there are few studies which examined the policy diffusion mechanism in local government. Therefore this study focus on the three policy diffusion mechanims; coercion, learning, imitation mechanism as well as three endogeous factors(political, financial, social characteristics in local government) to find what factors affect local policy adoption. We collected data from 227 local government’s conflict management ordinance from 2007 to 2015. We apply the Event History Analysis(EHA) to examine our hypothesis. The results show us that coercion and imitation mechanisms as exogenous factor influence the adoption of local conflict management ordniance and, political and social factors affect the adoption of local conflict management ordinance. Our results provide that frequency of conflicts as endogenous social factor has a positive effect on the adoption. This finding supports that many local government adoption of policy are made rationally by policy demand.