서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

연령증가에 따른 혈압요소들의 좌심실비대 및 관동맥질환과의 관련성

박재석,박창규,박미영,박재형,김용현,나진오,신성희,서순용,홍순준,박성미,임홍의,김응주,서홍석,오동주,노영무 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

강화된 응집이 활성탄 흡착에 미치는 영향

홍성호,김성진,오현제 대한상하수도학회 2003 상하수도학회지 Vol.17 No.3

It is a well known fact that enhanced coagulation can effectively eliminate natural organic matter known as precursor of disinfection by-products. In the study, effect of the enhanced coagulation was investigated by isotherm, kinetic and molecular weight distribution on activated carbon adsorption. The strongly adsorbable fraction was not preferably removed by enhanced coagulation. This conclusion could be drawn by that K value and initial concentration did not show much difference. Therefore, the effect of the enhanced coagulation on isotherm was to reduce the initial concentration over the each adsorbable fraction. When the enhanced coagulation was adapted for pretreatment for activated carbon adsorption the operation period could be extended to 3 to 4 times. The dominant molecular weight (MW) fraction was less than 1,000 for all samples. In conventional coagulation MW bigger than 10,000 was effectively removed. In the enhanced coagulation MW smaller than 1,000 was preferably removed. It was observed that the strongly adsorbable fraction had very strong relationship with the MW less than 3,000.

CdS 박막의 열처리효과에 관한 연구

홍성락,최치규,현동걸 제주대학교 1984 논문집 Vol.17 No.-

The annealing effects of CdS thin films prepared by the chemical vapor deposition method have been investigated. At 380℃, the annealing of CdS thin films for 30 minutes in H_(2) gas and vacuum (10^(-5) torr) has led to enhance the electrical conductivity and crystal structure of them. The resistivities are increased by as much as two and concentrations of the CdS thin films annealed have very fluctuating values, this may be expected to attniute to the surface scattering and surface potential resulted from the defects.

재발성 복부 통증을 호소한 환자에서 복벽에 발생한 자궁내막증 1예

홍현진,박성한,이준식,배용목,김지연,안광순,박선자 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.1

Endometriosis is the abnormal growth of endometrial tissue outside the uterine cavity. Endometriosis in the abdominal scar following cesarean section is very rare condition among the extrapelvic endometriosis. The frequency of abdominal wall endometriosis secondary to cesarean section is from 0.03% to 0.8% in some reports. It is difficult to diagnosed in spite of the typical symptoms. The typical symptom is aching swelling in the area of the surgical scar, which is influenced by the phases of menstruation. The definitive diagnosis is established by pathologic analysis. Surgical excision remains the treatment of choice. The majority of patients presented from 1 to 2 years after the precipitating operation. We experienced an unusual case of abdominal wall endometriosis presented over 10 years after cesarean section, who was admitted to our hospital complaining of recurrent left lower abdominal pain. So, we report this case with a brief review of the concerned literatures.

법랑질 표면처리방법에 따른 치면열구전색재의 미세누출에 관한 비교연구

현홍근,김정욱,이상훈 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.3

최근 air-abrasion기술이 새로운 법랑질 표면처리법으로 소개되고 있는데, 이것이 산부식 처리한 것보다 치면열구전색 전처리에 있어 더 나은 결과를 보이는지 연구할 목적으로.저자들은 표면처리법 및 재료에 따른 미세누출도의 차이를 비교해 보고자 하였다. 9개의 군으로 나눈 시편치아에 산부식(1, 4, 7군). air-abrasion(2. 5, 8군). ail·-abrasion후 산부식(3. 6. 9군) 처리한 후, 3종의 치면열구전색재(1∼3군 : Teethmate-F.4∼6군 Ultraseal XT plus, 7∼9군 : DenSeal)로 전색, 중합하여 색소침투도를 관찰하였으며, 각 시편의 전색재를 분리, 주사전자현미경으로 관찰하여 다음과 같은 결과를 얻었다. 1 표면처리법에 따른 미세누출도는 air-abrasion군, 산부식군 air-abrasion 후 산부식군 순으로 작아졌다(p<0.05) . 단. 7군과 9군간의 유의차는 없었다. 2.미세누출도는 산부식군에서 7군, 4군, 1군, air-abl·asion군에서 8군, 5군, 2군, air-abrasion후 산부식군에서 9군, 3군. 6군 순으로 작아졌으나. 각각 4군과 7군 2군과 5군 3군과 6군간의 유의차는 없었다. 3. SEM상에서, 산부식군은 비교적 긴 레진돌기가 규칙적으로, air-abrasion군은 �裏�레진돌기가 불규칙적으로, air-abrasion후 산부식군에서는 이들이 혼재되어 있는 모습으로 관찰되었다. Recently, the reintroduction of air-abrasion technology in dentistry has added a new potential method of pre-treating teeth prior to placing sealants. The purpose of this in vitro study was to investigate microleakages of several pit and fissure sealants following various surface pre-treatment methods to the enamel , because there was a question concerning the validity of claim that this method was better than the conventional acid etching. Permanent molars were divided randomly into nine groups and treated accordingly: acid etching(group 1, 4, 7), airabrasion(group 2, 5. 8), acid etching after airabrasion(group 3, 6, 9). Then the authors placed and cured the three kinds of sealants(group 1∼3 : Teethmate-F, group 4∼6: Ultraseal XT plus, group 7~9: Denseal) according to the manufacturer's order. They were observed to determine the degree of microleakage . And these specimens were separated from the corresponding enamels and examined by Scanning Electron Microscope. The following results were obtained : 1. In comparing microleakage among tooth surface treatment methods. air-abrasion group (group 2, 5, 8) showed the greatest microleakage. while combination(air-abrasion + acid etching) group showed the least (p<0.05) . However, no significant differences were found between group 7 and 9. 2. The mean microleakages were ranked as follows(p<0.05) : In acid etching groups. group 7> group 4> group 1. In air-abrasive groups. group 8 > group 5 > group 2. In combination groups, group 9 > group 3 > group 6. However. no significant differences were found between group 4 and 7. between group 2 and 5, and be-tween group 3 and 6. 3. SEM showed that comparably longer resin tags were distributed regularly in acid etching groups and that shorter ones irregularly in airabrasion groups. It also showed that these two kinds of tags were distributed simultaneously in combination groups.

정신병적 증상이 동반된 기면병 1예

홍승철,송정민,정종현,권용실,한진희,이성필 大韓神經精神醫學會 2003 신경정신의학 Vol.42 No.5

Narcolepsy is a sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucinations and disrupted nocturnal sleep. We report a patient with a diagnosis of schizophrenia who was subsequently diagnosed as narcolepsy. A case of a 22-year-old woman with concomitant narcolepsy and psychotic symptoms was discussed from a perspective of the diagnosis and therapeutic challenges, particularly on pharmcological treatment dealing with issues raised by their coexistence.

중년기 이후에 발병한 정신분열증에 대한 고찰

홍현상,채영래,백인호 大韓神經精神醫學會 1991 신경정신의학 Vol.30 No.6

It has been thought that the onset of schizophrenia is limited to youth. However, many European investigators have reported the occurrence of schizophrenia in later life. They have noted that the symptoms found in late-onset schizophrenia are not different from those noted in patients with early-onset schizophrenia. With the advent of the DSM-III-R(1987), there has been a renewal of interest in schizophrenia that arise for the first time in late life. This study was designed to examine some characteristic findings on demographics, clinical features, and treatment response in late-onset schizophrenia. The subjects consisted of 36 patients with late-onset(after 40) schizophrena and 72 patients with early-onset schizophrenia(before 40) by DSM-III-R who were admitted to the Department of Neuropshcyiatry of Kangnam St. Mary's Hospital, Catholic University Medical College from March 1982 to July 1990 The results were as follows : 1) The male to female ratio of the late-onset schizohprenic patients was 1 : 5. 2) The patients with late-onset schizophrenia were more likely to have grandiose delusions and auditory hallucinations than those of early-onset schizophrenia. 3) There was no significant difference in frequenty of clinical symptoms such as loosening of association, inappropriate affect, catatonia and response to neuroleptic treatment among each group. In light of these results, it seems likely that late-onset schizophrenia is somewhat different from, or might be a subtype of, more typical schizophrenia.

전통 고추장을 이용한 소스의 제조 및 특성

홍상필,김은미,조경현 한국식생활문화학회 2004 韓國食生活文化學會誌 Vol.19 No.2

To develope a sauce using Gochujang which can give foreigners good overall acceptance such as good flavor, taste, color, viscosity and versatility to many foods, we studied on the rheological properties and color control, recipes with spices, herbs, syrup, salt and flavor ingredients and sensory evaluation by Chinese, American and Japanese including Korean. From the survey, the Americans suggested that the proper fellow food of Gochujang sauce be fried chicken, barbecue, hamburger and pizza, and hoped to reflect red color, low viscosity, hot taste, low sweetness, salty and sourness and diet effect. The Chinese suggested pork and fried food as a fellow food with Gochujang sauce and showed similar opinion in the sensory attributes like the Americans except sweetness. When 5% of starch and xanthan gum was added to sauce, respectively, the yield stress of Gochujang sauce showed 33.21 Pa similar to tomato ketchup. In fluidity measured by voistic flow meter, Gochujang sauce showed 6.2 cm/30sec more or less faster than tomato ketchup which showed 4.7 cm/30sec. Gochujang sauce tended to show strong red color and lightness as pH decreased. The pH adjustant and Paprica oleoresin(2%) improved a value to 12.11 and L value to 24.24 similar to tomato kechup(a:12.42, L:25.48). The 1st gochujang sauce product showed 4.50 to 5.75 points in the overall acceptance in the consumer test including foreigners and koreans. However, the 2nd Gochujang sauce product showed 5.90 points and 6.30 points in the pizza and fried chicken, respectively, in the same consumer test. Therefore, we propose that Gochujang can be used for developing sauce products which is most acceptable for various foreigners.