부산의 한 대학병원에서 분리된 Acinetobacter baumannii의 PER-1 Extended-Spectrum β-Lactamase 생성 현황

김정만,강현경,정석훈,배일권,권수봉,조병규,김둘만,김현주,김아성 대한임상미샐물학회 2004 Annals of clinical microbiology Vol.7 No.1

Relationship between Meteorological Elements and Yield of Hot Pepper in Yeosu Area of Korea

Kwon,Byung-Sun,Choi,Seong-Kyu,Shin,Jeong-Sik,Shin,Jong-Sup,Shin,Dong-Young,Hwan,Kyu-Hyun,Kim,Hak-Jin,Kuk,Yong-In,Choi,Kyong-Ju 한국자원식물학회 2003 Plant Resources Vol.6 No.1

This study was conducted to investigate the relationships between yearly variations of meteorological elements and yearly variations of productivity in hot pepper. In addition, correlation coefficients among the yields and yield components were used to find out the relationships between meteorological elements and productivity. Yearly variation of the mean air temperature in May and July showed large with coefficients of variation(C.V.) of 25.0,8.9%, respectively, but the variation of the duration of sunshine in May were relative small. Yield and plant height was greatly with C.V. of 7.14,11.6%, respectively, diameter of fruit showed more or less C.V. of 2.28% and length of fruit showed less variation. Correlation coefficients between maximum temperature in period of cultivation from May and yield are positively significant at the level of 1 %. Correlation Coefficients between precipitation in period of cultivation from May to August and yield are negative significant at the level of 5 and 1 %, respectively. Correlation coefficients amount the plant height, length of fruit, diameter of fruit per plant, and seed yield were positively significant at the level of 1 %, respectively.

Yield of Rice Affected by Meteorological Elements in Yeosu Area of Korea

Kwon,Byung-Sun,Choi,Seong-Kyu,Shin,Jeong-Sik,Shin,Jong-Sup,Shin,Dong-Young,Hyun,Kyu-Hwan,Kuk,Yong-In,Park,Hee-Jin 한국자원식물학회 2003 Plant Resources Vol.6 No.2

This study was conducted to investigate the relationships between yearly variations of meteorological elements and yearly variations of productivity in rice. In addition, correlation coefficients among yield and yield components were used to find out the relationships between meteorological elements and productivity. Yearly variation of the mean air temperature in May was large with coefficients of variation(C.V.) of 25.0%, but the variation of the duration of sunshine in May were relative small. No. of panicles per hill and 1,000 grains wt. of brown rice were great with C.V. of 21.1, 19.7%, respectively, brown rice yield show more or less C.V. of 5.5% and milled rice show still less variation. Correlation coefficients between temperatures in period of cultivation from May and yield were positive correlations. Correlation Coefficients between precipitation in period of cultivation from Sep. to Oct. and yield are positive correlations. Correlation coefficients amount the panicle length, no. of panicles, no. of spikelets, ratio of ripened grains, 1,000 grains wt. of brown rice, milled rice yield, brown rice yield and milled rice yield were positively significant at the level of 1 %, respectively.

실비우스 수도를 경유한 뇌낭미충 낭종의 이주 -증례 보고-

김정훈,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

임상검체에서 분리된 그람 음성 세균들에 대한 Isepamicin의 시험관내 항균력

권현희,박수진,소민욱,박현구,최성호,김미나,최상호,정진용,우준희,김양수 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background : The increasing incidence of multidrug-resistant gram-negative bacteria causing nosocomial infections is an important clinical problem. Isepamicin is a recently developed aminoglycoside which has been known to have potent activity against gram-negative organisms. We evaluated the in vitro activities of isepamicin and other aminoglycosides against a large number of gram-negative organisms. Materials and Methods : We tested the in vitro antimicrobial activities of isepamicin, amikacin, gentamicin, and tobramycin against 566 gram-negative organisms collected between January 2006 and June 2006 in Asan Medical Center. Minimal inhibitory concentrations (MICs) were determined and interpreted according to the recommendations of Clinical and Laboratory Standard Institute (CLSI). The breakpoint MIC used for interpretation of isepamicin was MIC≤16 ㎍/mL as susceptible, 32 ㎍/mL as intermediate, and 64 ㎍/mL as resistant. Results : The MIC_(50)/MIC_(90) of isepamicln for Escherichia coli, Klebsiella pneumon/ae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacter cloacae were 1/2, 0.5/>128, 4/16, 16/>128, and 1/2 ㎍/mL, respectively. The susceptibilities for E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, and E. cloacae were 100%, 86.4%, 89.7%, 50.0%, and 96.6%, respectively. For E. coli, K. pneumoniae, P. aeruginosa, and E. cloacae, isepamicln had better in vitro activities than gentamicin and tobromycin, and had similar activities with amlkacin. For A. baumanii, all four tested aminoglycosides had similar in vitro activities. Conclusion : Isepamicin had excellent in vitro activities against gram-negative organisms, except A. baumanii. The overall in vitro activities were similar with amikacin. 목적 : 그람 음성 세균은 다양한 지역사회 및 병원 획득 감염의 원인균이다. 최근에는 병원 감염을 일으키는 그람 음성 세균에서 항균제 내성균의 출현과 확산이 큰 문제가 되고 있다. Isepamicin은 최근에 소개된 gentamicin B의 유도체로 외국에서의 연구에 의하면 그람 음성 세균들에 대한 항균력이 우수함이 보고 된 바 있다. 본 연구에서는 우리나라의 임상 균주들을 대상으로 그람 음성세균에서 isepamicin의 시험관내 항균력을 기존의 아미노배당체 제재들과 비교하여 평가하고자 하였다. 재료 및 방법 : 2006년 1월에서 6월 사이에 서울아산병원 환자에서 분리된 Escherichia coli 113 균주, Klebsiella pneumoniae 110 균주, Pseudomonas aeruginosa 117 균주, Acinetobacter baumannii 108 균주, 그리고 Enterobacter cloacae 118 균주를 대상으로 isepaimcin, amikacin, gentamicin, tobramycin에 대한 최소억제농도(minimal inhibitory concentration, MIC)를 한천 희석법(Mueller-Hinton Agar)을 이용하여 측정하였다. 감수성여부는 CLSI 기준에 따랐으며, isepamicin은 MIC≤16㎍/mL를 감수성, MIC=32 ㎍/mL를 중등도 내성, MIC≥64 ㎍/mL를 내성으로 판정하였다. 결과 : Isepamicm의 E. coli, K. pneumoniae, P. aeruginosa, A baumannii, E. cloacae에 대한 MIC_(50)/MIC_(90)은 각각 1/2, 0.5/>128, 4/16, 16/>128, 1/2 ㎍/mL였고, 항균제 감수성률은 차례대로 100%, 86.4%, 89.7%, 50.0%, 96.6%였다. 기존 아미노배당체 제재들과 비교하면 E. coli, K. pneumoniae, P. aeruginosa, E. cloacae에서는 amikacin과 비슷한 감수성률을 보였고, gentamicin과 tobramycin보다 높은 감수성률을 보였다. A baumannii의 경우 isepamicin의 감수성률이 50.0%로 비교적 낮았지만 amikacin, gentamicin, tobramycin도 각각 50.0%, 46.3%, 47.2%의 감수성률을 나타내어 4가지 항균제가 모두 비슷한 항균력을 보였다. 결론 : Isepamicin은 그람 음성 세균들에 있어 기존의 아미노배당체 제재들과 비교했을 때 amikacin과는 동등한 시험관내 항균력을 보이고 gentamicin, tobramycin보다 뛰어난 시험관내 항균력을 보여 사용이 유망한 아미노배당체 중 하나라 생각된다.

Effect of Fertilizer Levels on Growth Characters, Dry Matter Yield and Nutrient Quality of Forage Rape in Spring Sowing

Kwon,Byung-Sun,Shin,Jeong-Sik,Shin,Dong-Young,Hyun,Kyu-Hwan,Park,Hee-Jin,Sin,Jong-Sup,Seong-Kyu 한국자원식물학회 2003 Plant Resources Vol.6 No.2

To find out the optimum fertilizer level for high yielding variety, Velox, experiment was conducted with 15 compositions of fertilizer levels at the experiment field of forage crop in Sunchon National University from Mar. 2000 to Aug. 2000. The effects of nitrogen fertilizer on plant growth were significant but increasing rate of application in potassium and phosphate fertilizers above 6 kg/a had negligible effects on plant growth. The optimum nitrogen application level of fertilizers turned out to be 16-6-6 kg/l0a of N-P2O5-K5O. Content of crude protein was highest and that of crude fiber such as NDF, ADF, cellulose and lignin were lowest at this rate of fertilizer application. Furthermore, IVDMD was high and dry matter yield were highest at the optimum raterate

LC-MS/MS를 이용한 S.D. Rat 혈장 중 Arctiin 분석법 개발

송병정,채정우,백현문,권광일 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

KIOM-MA128 is a novel oriental herbal medicine which is for atopic dermatitis and asthma. The purpose of this study was to develop on analytical method of arctiin in rat plasma after oral administration of KIOM-MA128. Analyte was separated on a Atlantis dC18 reverse phase column, using gradient mobile phase (A:B = acetonitrile: 0.1% formic acid in water) at a flow rate of 0.3 mL/min. Detection was performed by electrospray positive ionization mass spectrometry using multiple reaction monitoring of the transitions of arctiin at m/z 552.4 → 372.8 and internal standard (carbamazepine) at m/z 237.0 → 194.5. The limit of quantification was 1 ng/mL for arctiin. The precisions were lower than 15% and the accuracy was between – 12.21 and 3.2%. The maximum concentration found in plasma samples was 4.1 ng/mL. The present method was successfully developed for detecting arctiin in plasma and this results would be utilized to the further study.

지방척수수막류 14례의 임상 분석 : Clinical Analysis of 14 Cases

이정호,신규만,김명현,송준혁,박향권,김성학,박동빈 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.6

Lipomyelomeningocele is the most common malformation leading to spinal cord tethering. Nonetheless, these lesion continues to pose a challenge in patient management. The purpose of this study was to identify the clinical feature, candidate for surgical repair, and outcome of lipomyelomeningocele in young children and adults. We studied the magnetic resonance images and/or lumbar myelo-CT of lipomyelomeningocele performed between January 1987 and September 1995 at our institutions and reviewed the pertinent medical records and radiologic studies to determine clinical feature, surgical candidate, and outcomes of these patients. Of the 14 cases(11 female and 3 males) studied, the most common factor that caused these patients to seek help was the cosmetic effect of the mass on their back, followed by urinary incontinence, and weakness of lower extremities. The patients' age ranged from 2 months to 21 years(mean, 5.0 years). All the patients underwent immediate surgical management that consisted of removal of lipoma, untethering of the cord, and complete dural sac repair. Follow up for these patients ranged from 6 to 82 months(median, 54 mo). None of the patients that underwent surgical correction before the emergence of neurological deficit had ever developed neurological deficits at the end of the follow up. However a few of the patients, despite presented with neurological deficits or urinary incontinence at the time of surgery, improved significantly. In conclusion, early detection and prophylactic surgery is imperative to prevent permanent neurological deficits and urinary dysfunction.

학습공동체 프로그램 질과 인지적 성취 간에 집단응집성, 협력적 자기조절의 매개효과

유지현(Yu, Ji-Hyun),이숙정(Lee, Sook-Jeong),권진백(Kwon, Jin-Baek) 한국경영교육학회 2021 경영교육연구 Vol.36 No.1

[연구목적] 본 연구는 비교과 프로그램 형태의 학습공동체 운영 개선을 위해 학습공동체 프로그램 질 척도를 개발하고, 학습공동체 프로그램의 질과 인지적 성취의 관계에 집단응집성 및 협력적 자기조절의 매개효과를 검증하고자 하였다. [연구방법] 학습공동체 관련 선행연구들과 S대학에서 운영한 학습공동체 만족도 조사 및 성찰일지를 분석하여 학습공동체 프로그램 질 척도 예비문항을 개발하고, 학습공동체에 참여한 대학생 299명을 대상으로 설문조사를 실시, 분석하였다. 또한 집단응집성 및 협력적 자기조절의 매개효과를 확인하기 위해 대학생 322명을 대상으로 설문조사를 실시, 분석하였다. [연구결과] 학습공동체 프로그램 질 척도는 11개 문항, 단일요인으로 개발하였으며, 탐색적 및 확인적 요인분석, 신뢰도 계수 산출을 통해 안정적인 척도임을 확인하였다. 또한 학습공동체 프로그램 질과 인지적 성취 간에 집단응집성 및 협력적 자기조절의 매개효과가 통계적으로 유의한 것으로 나타났다. [연구의 시사점] 본 연구에서 개발한 학습공동체 프로그램 질 척도를 활용함으로써 프로그램의 내실화 및 질 관리 방안을 수립할 수 있다. 또한 집단응집성 및 협력적 자기조절의 중요성을 규명함으로써 학습공동체 프로그램 운영의 시사점을 제공하였다. [Purpose] The purpose of this study was to develop the learning community program quality scale for improving a learning community program and to verify the mediating effect of group cohesion and collaborative self-regulation on the relationship between program quality and cognitive achievement. [Methodology] A questionnaire survey of 299 university students was conducted to develop the learning community program quality scale. To confirm the mediating effect of group cohesion and collaborative self-regulation, a questionnaire survey was conducted on 322 college students. [Findings] The learning community program quality scale was developed with 11 items and a single factor, and it was confirmed to be a stable scale. And, it was found that the mediating effect of group cohesion and collaborative self-regulation between the learning community program quality and cognitive achievement was significant. [Implications] Implications for the management of learning community program to promote group cohesion and collaborative self-regulation were provided.

한국 재래 나물콩 품종 및 계통의 콩나물 특성

황영현,이정동,조호영,권택화,정연신 慶北大學校農業科學技術硏究所 2002 慶北大農學誌 Vol.20 No.-

우수한 특성을 가진 나물콩 품종 육성을 위하여 국내 재래 나물콩 계통의 콩나물 특성을 분석한 결과는 다음과 같다. 1. 공시된 301품종 및 계통의 콩나물 전체길이의 범위는 9.5∼23.0cm, 하배축 길이는 5.9∼15.1cm, 뿌리 길이는 3.2∼9.2cm로 다양한 변이를 보였고, 수율에서도 121∼695%로 다양하게 분포하고 있다. 2. 공시된 301품종 및 계통의 종피색에 따른 콩나물 수율은 혼색종피종에서 409%로 가장 높게 나타났고, 백립중에 따른 콩나물 수율은 소립종일수록 높은 경향이었으며, 잔뿌리수는 흑색종피종과 갈색 종피종에서 현저히 적었다. 3. 콩나물 길이와 전체길이에 대한 뿌리길이의 비율, 수율을 기준으로 한 공시품종 및 계통들의 분포에서 장려품종보다 우수한 특성을 가지는 다수의 재래계통이 분포하고 있었다. 4. 콩나물 하배축의 색도는 백색도(L값)에서 장려품종이 재래계통에 비해 백색에 더 가까웠고, 적색도(a값)와 황색도(c값)는 장려품종보다 재래계통에서 높은 경향이었다. To develop good soybean varieties for sprouts. 285 indigenous lines and 16 recommending varieties were evaluated by the sprout and agronomic characteristics. The range of whole length, hypocotyl length, root length, and yield rate of sprouts was 9.5~23.0cm, 5.9~15.1cm, 3.2~9.2cm, and 121~695%, respectively. Yield rate of sprouts was the highest, 409%, in the lines of mixed seed coat color. At the same time, it was reversely proportional to seed weight : the smaller the seed weight, the higher the yield rate as in all other reports. The number of roots was significantly fewer in the lines of the black and the green seed coat color than others. Based on whole length, rate of root length, and yield rate of sprouts, many indigenous lines were evaluated much better than recommending varieties. In the hypocotyl color of sprouts, the brightness was higher in improved variety than indigenous lines but vice versa in redness and yellowness in general.