심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

Tool을 이용한 요구 명세서 작성

신재선,이성주 조선대학교 기초과학연구소 1988 自然科學硏究 Vol.11 No.1

Jae Seon Shin Sung Joo Lee This thesis describes an approach to requirements specification in which different aspects of requirements specification are expressed using multiple models. This thesis also describes an interactive software tool named Model-Box, Which supports the construction and analysis of requirements models via textual and graphical representations. Model-Box allows users to define appropriate new models for the aspects they want to describe, without restriction to a single modeling methodology.

비호지킨림프종 환자에서 발생한 폐 효모균증 1예

장재혁,송치원,심병용,이동건,변재호,정정임,이교영,홍영선,신완식,김춘추,이경식 대한감염학회 2003 감염과 화학요법 Vol.35 No.3

저자들은 비호지킨씨 림프종 환자에서 항암 치료 후 질환의 진행성 병변과 감별을 요했던 우폐 중엽의 단발성 종괴를 흉강경하 생검으로 폐 효모균증을 확진하고 amphotericin B와 fluconazole로 치료한 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Non-Hodgkin's lymphoma is monoclonal expansion of malignant B or T cells. The immunocompromised status in this disease is accompanied by many infections. The cryptococcosis, caused by Cryptococcus neoformans, frequently occurs in leukemia, Hodgkin's disease, sarcoidosis, diabetes mellitus, tuberculosis, and long-term steroid-using patients. Recent increasing incidence of fungal infection could be due to the spread of AIDS and transplantation. We experienced one patient with lung mass in Non-Hodgkin's lymphoma after three cycles of chemotherapy, which could not be discriminated from the newly developed lymphoma mass. Cryptococcus neoformans was isolated from the lung tissue obtained by thoracoscopic biopsy. Herein we report this case with brief review of pertinent literature.

지역사회획득 폐렴의 치료지침 권고안

송재훈,정기석,강문원,김도진,배현주,서지영,심태선,안중현,안철민,우준희,이남용,이동건,이미숙,이상무,이영선,이혁민,정두련,지역사회획득 폐렴 치료지침 제정위원회 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

A successful therapy of community-acquired pneumonia requires appropriate empirical antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of pneumonia can differ by country. Therefore, an ideal treatment guideline of community-acquired pneumonia should be based on the studies performed in each country. We developed a treatment guideline for community-acquired pneumonia in immunocompetent adults in Korea. This guideline was developed by the joint committee of the Korean Society for Chemotherapy, the Korean Society of Infectious Diseases, and the Korean Academy of Tuberculosis and Respiratory diseases.

GC/NPD를 이용한 다성분 잔류농약의 동시분석

김우성,이선화,김상엽,정동윤,김재이,이영자,이홍재,정성욱,박흥재 한국환경과학회 2003 한국환경과학회지 Vol.12 No.10

Pesticides were extracted from samples with 70% acetone and methylene chloride in order, and then cleaned up via open-column chromatography apparatus packed with fiorisil, and finally analyzed simultaneously the organophosphorus pesticides using GC/NPD, Ultra-2 and Ultra-1 fused silica capillary columns were used to separate and identify the products. Recovery of most analytes from soybean sample, taken from pesticide residues well, was greater than(80%) for all except(6) analytes. This method can simultaneously determine multiple pesticides with a high degree of accuracy and precision.

건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

석탄폐석의 골재자원화에 관한 연구

이재장,김교선 강원대학교 석재복합신소재제품연구센터 1996 석재연 논문집 Vol.1 No.-

석탄폐석의 골재 자원화에 필요한 폐석 정제 기술에 수반되는 전처리 단위공정에 대하여 전반적으로 살펴보고 각 단위공정의 종류, 이론적 배경, 특성 및 장단점 등에 대하여 알아보았다. 특히 석탄페석의 전처리 단위 공정으로 사분공정, 분쇄공정, 혼합 공정 등에 대하여 자세히 알아보았다. 사북(동원)지역 상부의 폐석은 휴발분 4.6%, 고정탄소 2.7%, 황 0,26%이고, 하부의 폐석은 휴발분 5.7%, 고정탄소 6.4%, 황 0,25%이었다. 상부의 폐석은 10cm이하 크기로 구성되어 있으며 3메시 이하의 입단은 25.2%이었고, 하부폐석의 3메시 이하 입단은 53.2% 이었다. 예비혼합조의 기본설계를 위한 예비실험으로써 실험실용 도우넛형 저장조를 아크릴로 제작하여 모래, 석탄,소금 등을 시료로 하여 예비혼합실험을 하였다. 실험방법은 소금을 tracer로하여 모래 또는 석탄을 예비혼합조에 계단입력 또는 충격입력을 가하여 예비혼합조 출구에서의 응답특성을 관찰하였으며 출구에서의 전기전도도 변화를 측정하였다. 실험실용 도우넛형 저장조의 실험결과 충분한 혼합효과를 얻고 있었으며 특히 시간에 따른 석탄 폐석질의 변화를 급격히 감소시킬 수 있음을 알 수 있었다. 본 실험에서 예비저장조 중앙부분의 유량이 바깥 쪽에 비해 대체로 많은 편이었으며 그 결과로 계단입력의 응답특성이 이론적 예측보다 원만히 증가하고 있었다. 앞으로의 연구에서는 예비혼합조의 벽면 각도, baffle의 각도, 간격 및 너비 등을 사용하는 분체의 물성에 관련시켜 체계적으로 설계하는 연구가 필요하다. In this study, we investigated several unit processes to pretreat coal mine wastes to produce aggregates. We also analysed the kinds, theoretical backgrounds, characteristics, merits and demerits of each unit process. The process of screening, crushing and mixing were analyzed, more specifically, to pretreat the coal mine wastes. It is found that the congromerates, sandstone, shale, coal shale and clay are included in coal mine wastes and the carbonates and sulfates are required to be eleminated from coal mine wastes to produce aggregates. The coal wastes from the upper part of coal mine in Sabuk(Dongwon) are observed to have the content of volatile matter, 4.6%, fixed carbon, 2.7% and sulfur, 0.26%, respectively, while the coal wastes from the lower part of coal mine waste pile have the content of volatile matter, 5.7%, fixed carbon, 6.4% and sulfur, 0.25%. The size fraction of sample under 3 mesh size is 25.2% for fresh samples from upper part of coal waste pile and is 53.2% for coal wastes from lower part. The doughnut-type preblending storage tank were made of acryl and the preliminary experiments were performed with sand, coals and salts to get the basic data to design the preblending storage tank. The sands or coals were introduced into the preblending storage tank with step input or impulse input of salts as tracer and the response characteristics of storage tank were at the outlet of storage tank by measuring the change of electrical conductivities. We could observe the sufficient preblending effects by these experiments of doughnut-type storage tank and, especially, we could reduce the change of coal waste quality as a function of time. In these experiments, we observed the higher flow rates of powder at the center of blending tanks than in the region near the wall of storage tank and, as a result, the response characteristics of step input was increasing more slowly than that expected theoretically. Further systematic studies in preblending storage tank are required about the angle of surface wall, and the angles, spaces and widths of baffles in correlation with the properties of powders being treated.

21세기 새로운 시대를 준비하는 원광대학교 의과대학의 교육목표 개정과정

이학승,김요식,송윤강,오재민,양연식,정선관 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

교육목적은 대학의 교육이 지향하는 대전제이다. 그러므로 대학교육 목적과 목표가 어떤가에 따라 교육과정과 교육방법이 달라진다. 원광대학교 의과대학의 교육목표는, '지덕겸수'로 요약되는 '과학과 도학을 겸비한 전인교육'의 건학정신과 '학술탐구'와 '덕성함양'의 원광대학교 교육목표와 일치하게 현재까지 유지되었다. 그러나 현행 교육목표의 여러 문제점이 발견되었고, 시대상의 변화에 따라 원광대학교 의과대학에서도 사회적 변화 빛 의료인에 대한 시대적 요구에 걸맞은 의학교육의 목적 및 목표의 재설정 과정을 시작하게 되었다. 그 결과 개정 작업을 통해 새로운 교육목표를 설정하게 되었으며 그 내용은 다음과 같다. 1. 기본진료능력을 지닌 의사를 양성한다. 2. 원불교 교리 이념을 반영한 윤리적, 도덕적인 의사를 양성한다. 3. 평생 학습하는 연구하는 의사 혹은 의과학자를 양성한다. 4. 사회적 책무를 수행하는 리더십을 갖춘 의사를 양성한다. 5. 지역 사회에 공헌하는 봉사정신을 갖춘 의사를 양성한다. Purpose : With the changes to the medical environments and to the medical educational systems, we aimed to evaluate the current mission statement of the School of Medicine, Wonkwang University, and to revise it. Methods : To establish the new goal and mission statement, a Special Committee for the Revision of Medical School Mission and advisory group were organized in 2008. This special committee conducted through five steps of action, which are composed of investigation, education, development, surveillance of various opinions, and announcement. Results : For the development of new goal and mission, the revised, final goal and mission statements decided through the five steps of action. The new mission of Wonkwang University School of Medicine was as follows; 1. Doctor who can diagnose and treat easily 2. Ethical and moral doctor who practice Won Buddhism 3. Doctor or Medical Scholar who studies lifelong study 4. Doctor who has leadership to social responsibility 5. Doctor who goes into service to a local community. Conclusion : The authors expect that the new goal and mission of Wonkwang University School of Medicine would be helpful in giving the guideline on the educational process of medical school and will give the information to reform the medical school system according to the rapidly changing educational environment.