http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
간경변증 환자에서 도플러 초음파를 이용한 신저항 계수(RI)의 임상적 의의
홍영선,박사영,심기남,김도영,문일환,유정현 梨花女子大學校 醫科大學 醫科學硏究所 1996 EMJ (Ewha medical journal) Vol.19 No.1
Cirrhotic patients may exhibit circulatory derangement and renal dysfunction during the clinical course. Renal dysfunction on cirrhosis can occur without specific causative factors. This functional renal failure in cirrhosis is considered as a consequence of renal vasoconstriction. These alteratons of renal hemodynamics are already present in the early phase of the disease, even in the condition that the conventional kidney function tests are normal. A new method for noninvasive evaluation of arterial tone is duplex Doppler sonography. Among the various sonographic indices proposed, the renal resistive index(RI) is the most widely used for the estimation of intrarenal arteriolar vascular resistence. This study was performed to evaluate the role of Doppler sonography in early detection of renal dysfunction and to assess the clinical significance of RI. In 25 cirrhotic patients without overt kidney failure and ten control subjects, the RI of the acurate artery in both kidneys was measured by Doppler sonography. The mean RI of cirrhotic group was significangly higher than that of control subjects(0,68±0.08 vs -0.62 ±0.05,p<0). Accordiing to Child class, the RI showed increasing tendency from A to C, through witout statistical significance. In this study, the RI was significantly inversely correlated with 24hr urinary sodium amount(r=-0.39, p<0,05)and correlated with serum creatinine(r=6.60,p<0.01). This study indicates that the measurement of RI is a sensitive method to assess intarenal hemodynamics and to detect early changes of the renal dysfunction in cirrhotic patients.
MODERNITY AND WELFARE IN GERMANY, 1870-1945
홍영선 한국독일사학회 2013 독일연구 Vol.- No.25
복지와 근대성은 근대 독일사 서술에서 중심 개념으로 자리 잡아왔다. 그러나 복지와 계몽주의에 대한 우리의 이해를 오랫동안 규정해온 근대성과 자유주의와 해방 사이의 규범적 연결이 근대 독일사의 이해를 가장 진척시켰던 저술들에 의해 의문시됨으로써 이 발전은 중요한 이론적 결과들을 야기하고 있다. 복지에 대한 최근의 연구들은 독일 제국의 근대성을 강조하면서, 동시에 진보적인 사회 개혁이 빌헬름 시기로부터 나치의 사회 및 인종 정책에 이르는 중요한 연속성이 되었던, 자유를 제한하는 억압적 차원도 가지고 있다고 제시한다. 그뿐 아니라 나치 독일을 ‘인종 국가’로 보는 최근의 해석은 인종적으로 가치 있는 주민들을 향상시키기 위한 진보적 사회 프로그램들과 인종적으로 열등한 자들을 주변화하기 위한 부정적 프로그램들이 일관적이며, 근대적이며, 그러나 명확히 자유를 제한하는 복지 개념의 두 측면을 대표한다는 것을 강조해왔다. 이 논문은 복지와 사회 개혁에 대한 급증하는 문헌들이 복지와 근대성 사이의 모호한 관계를 어떻게 다루어 왔는지 살펴보며, 나치 독일을 ‘복지’ 국가로 성격 규정하는 데 내포된 이론적 도덕적 문제들에 초점을 맞춘다.
홍영선,윤해성,문종설,조영만,안성훈 한국정밀공학회 2016 International Journal of Precision Engineering and Vol.17 No.7
Tool wear is one of the most important parameters in micro-end milling, and can be used to monitor the condition of the machine and the tool. A micro-end mill has different characteristics from a macro-scale end mill; in particular, shank run-out (which is negligible in the macro-scale tool due to the low aspect ratio) is significant in micro-end milling, inducing excessive tool wear and reduced tool life and leading to sudden, premature failure. In this paper, a novel tool-wear monitoring method is described for determining the state of a micro-end mill using wavelet packet transforms and Fisher’s linear discriminant. Force and torque signals were measured using a dynamometer and were used to reflect geometric changes in the micro-end mill due to wear. Because of the small signal-to-noise ratio, sensor signals measured during the milling process were periodically averaged, and the resulting singleperiod signals provided improved efficiency of feature extraction using wavelet packet transforms. The extracted features were classified in the wavelet domain and used to determine the tool state employing a hidden Markov model. The recognition results were compared with those of an energy-based monitoring technique, and we found that our method could determine the tool state more accurately for both normal wear and premature failure of micro-end mills.
갑상선 결절에서 미세침 흡인세포검사 및 침생검의 진단적 가치
홍영선,김희진,성연아,경난호 梨花女子大學校 醫科大學 醫科學硏究所 1996 EMJ (Ewha medical journal) Vol.19 No.4
Objectives : Thyroid nodule is a common clinical problem and it is important to distinguish benign from malignant nodule. Although features found on history taking, physical examnation and imaging studies help the diagnosis, fine needle aspiration(FNA) has been accepted as an accurate and reliable diagnostic procedure of thyroid nodule. This study was aimed to assess the values of FNA and needle biopsy in the diagnosis of thyroid nodules. Methods : We reviewed the medical records of the 405 patients who underwent FNA and needle biopsy for the diagnosis of thyroid nodule form September 1993 to July 1996. Results : The 414 fine needle aspiration cytologic specimens were obtained from 405 patients(male : 26, female : 379). 390 cases(94.2%) were adequate for cytologic diagnosis. And the diagnosis showed benign in 357(91.5%), malignancy in 20(5.1%) and suspicious malignancy in 13(3.3%). Among the 357 benign cases, 104 cases were benign cysts, 163 cases were adenomatous goiter and 45 cases were follicular adenoma. 46 patients underwent thyroidectomy after FNA and 21 patients(45.7%) were diagnosed as having carcinoma. The sensitivity and specificity of FNA in diagnosing malignancy were 65% and 82%, respectively, with an accuracy of 74%. Of 46 patients, needle biopsy was done in 41. The sensitivity and specificity of the needle biopsy were 79% and 73%, respectively. And the accuracy was 76%. Hoarseness was developed in one patient after FNA and needle biopsy, and small amount of hemoptysis was developed in another patient after FNA. Conclusion : Although it had been expected that needle biopsy may increase the diagnostic accuracy, our study didn't show the superiority of needle biopsy as compared with FNA. FNA has limitations in suspicious and nondiagnostic results but it is a safe, simple, reliable and cost-effective means of evaluating thyroid nodules. It is the preferred initial diagnostic method in all patients with thyroid nodule.
재발된 혹은 불응성 비호지킨 림프종에서 고용량 항암요법과 표준 구출요법의 비교
홍영선,민창기,김정아,김희제,엄현석,조석구,이종욱,진종률,한치화,최일봉,박재후,민우성,김춘추,김동집 대한조혈모세포이식학회 1997 대한조혈모세포이식학회지 Vol.2 No.1
Background: Patients with intermediate- or high-grade non-Hodgkin's lymphoma (NHL) who have a relapse or refractoriness after initial standard chemotherapy generally have a poor prognosis. Conventional salvage treatment can induce lengthy remission. It is, however, not generally agreed that long-term survival has been expected in patients receiving salvage chemotherapy. The combination of high dose therapy and autologous stem cell transplantation has been considered promising in refractory or relapsed patients with NHL. Methods: The response rate and survival (disease-free and overall survival) of 15 patients with relapsed or refractory NHL who only received salvage chemotherapy was compared with those of 14 patients who has been assigned to receive high dose therapy and autologous stem cell transplantation. Results: the overall rate of response to salvage chemotherapy was 13% but that of high dose therapy with stem cell support was 58%. Disease free survival (DFS) in the salvage chemotherapy group was very low; only 2 patients survived in remission without a relapse of disease in long duration. On the contrary the rate of DFS in the transplantation group was 48% at 3 years. At 3 years, the rate of overall survival (OS) was 17% in the group receiving salvage chemotherapy and 31% in the transplantation group. Conclusion: As compared with salvage chemotherapy, treatment with high dose therapy and autologous stem cell transplantation increases disease-free and overall survival in relapsed or refractory patients with non-Hodgkin's lymphoma.