직장에 발생한 원발성 악성 흑색종 1예

이석주,김광일,김동호,김홍성,우상민,최덕례,정현용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

An extremely rare case of primary melanoma involving only rectum is reported. This 59 year-old male patient was admitted to the hospital because of hematochezia, difficulty of defection. Endoscopic examination and radical excision showed polypoid lesion with ulceration which measured 6x6x3cm in 2cm from the anal verge. Histopathologic, H&E stain and electron microscopic examination(EM) were performed from endoscopic biopsies and excisional mass. We are reporting a case primary rectal melanoma with brief review of literature.

습진성 피부질환에 대한 Hexomilone^(�) 치료의 임상연구

이대성,조광윤,허동,김형옥,김정원 최신의학사 1984 最新醫學 Vol.27 No.11

혈우병 환자에 동반된 자발성 후복막강 출혈

김광일,김동호,우상민,이석주,김홍성,조인성,윤환중,조덕연,김삼용 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.1

Spontaneous retroperitoneal hemorrhage due to hemophilia A with impaired coagulopathy is very rare. Spontaneous retroperitoneal hemorrhage has been recorded as having originated from many retroperitoneal organs and blood vessels, and it may be due to local and/or systemic factors. In the majority of the patients, kidney and adrenal gland were the major site of hemorrhage. The systemic causes of spontaneous retroperitoneal hemorrhage are anticoagulation therapy and chronic hemodialysis. During the course of these treatments, hemorrhagic complications may occur at many site, including the retroperitoneal space. Blood dyscrasias including leukemia, polycythemia, sickle cell trait and hemophilia have been reported associated with spontaneous retroperitoneal hemorrhage. We report a case of spontaneous retroperitoneal hemorrhage occurred in a gemophilia A patient with brief review of literature

인장하중을 받는 의사등방성 복합재 적층판의 피로손상

양광영,임경택,이동하,김택현,김인권 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.1

The purpose of this work is to investigate fatigue damage of quasi-isotropic laminates under tensile loading in different directions. Low cycle fatigue tests of [O/-60/+60]s laminates and [+30/-30/90]s laminates were carried out. Materials systems used are AS4/Epoxy and AS4/PEEK. The fatigue damage of [+30/-30/90]s is very different from that of [O/-60/+60]s. The position of delamination generated at AS4/Epoxy and AS4/PEEK laminates were differentiated by the matrix difference that is, we suppose, the value of both G (critical energy release rate of mode-I) and G (critical energy release rate of mode-Ⅲ) difference. The experimental results are compared with the result obtained from the method of determining strain energy release rate components proposed by the authors.

이원화, 다계화, 네트워크 구축전략 : 일본의 대아시아 직접투자전략

조동성,이광현,이윤철,김태현 韓國國際經營學會 1995 國際經營硏究 Vol.6 No.1

본 연구는 1985년 이후 엔고와 더불어 급증한 일본의 대아시아 직접투자를 기업전략적인 차원에서「이원화전략」,「다계화전략」,「네트워크 구축전략」의 관점에서 설명하고자 한다. 여기서 이원화 전략이란 기술전파를 막기 위해 첨단기술을 요하는 고부가가치 제품은 국내에서 생산하고, 노출가능한 기술을 사용하여 생산하는 중저가 제품은 해외에서 생산함으로써 후발개도국들의 추격을 따돌리는 전략을 의미한다. 한편 다계화전략이란 투자국의 경제 발전에 따라 일본기업의 생산입지를 단계적으로 변화시키는 전략이다. 마지막으로 네트워크를 구축전략이란 일본기업이 아시아 투자가 개별적으로 이루어 지지 않고, 총체적인 경쟁우위를 향상시키기 위해 기존 해외 네트워크의 연장선 하에서 이루어진다는 것이다. 이러한 일본기업의 아시아 해외투자전략에 대응해서 전통적으로 일본으로부터 기술을 수입해 온 한국기업이 일본기업을 추격하기 위해서는「전문화전략」,「투자지역 선도전략」및「보완적 네트워크 구축전략」을 채택해야 할 것이다. 한편 한국과 같은 선발개도국을 모델로 하여 경제개발을 추구하고 있는 다른 아시아국가들 역시 본 논문을 통해 일본기업들의 전략적 의도를 파악하고, 이에 대응하기 위해「자체능력 개발전략」및「네트워크 연결전략」을 채택할 필요가 있다.

청각 자극용 전기자극기 개발

허승덕,정동근,김리석,김광년,강명구,김재룡,김기련 한국음성과학회 2004 음성과학 Vol.11 No.3

This paper introduces a development of an electrical stimulator for auditory stimulation. The electrical stimulator is useful in neurotological diagnosis, audiological evaluation, candidate selection for cochlear implantation, optimal device selection and decision making of MAP strategy for severe-to-profound hearing impaired persons. The development was based on sound parameters of auditory brainstem responses and auditory electrophysiological characteristic such as effective firing of auditory nerve and recording evoked potentials during refractory period of neuron. Besides pulse parameter could adjustable by programming for more varied electrical stimulation evoked response audiometry. Using the electrical stimulator, electrical square pulse was applied to promontory, and electrically evoked auditory brainstem response and electrically middle latency response were successfully recorded in cats.

철을 오염시킨 n-GaAs의Photoreflectance에 관한 연구

유재인,문영희,이동울,이정열,배인호,장광수 嶺南大學校 基礎科學硏究所 1998 基礎科學硏究 Vol.18 No.-

We investigated the variation of PR signals for n-GaAs surface treated with Fe as annealing method. The samples were annealed by isochronal(200∼600 ℃, 10 min) and isothermal(300 ℃, 10 ∼60 min) method. In PR signals measured from isochronal annealed samples, the rate of intensity decreasing for n-GaAs was 49%, and that for n-GaAs surface treated with Fe was 66%. We assumed that the large amount of decreasing intensity for Fe contaminated sample caused by decreasing carrier density due to increasing of ?? neutral acceptor at higher annealing temperature. In PR signals measured from isothermal annealed samples, the signals for annealed n-GaAs decreased with increasing annealing time, and the signals for n-GaAs surface treated with Fe continuously increased with increasing annealing time. It can be assumed that the increasing of PR intensity for Fe contaminated samples as annealing time caused by the diffusion of Fe atoms from the surface.

통풍성 관절염의 임상적 고찰

윤채중,정승문,김영학,김동규,허광식,김태원,배학연,정종훈,이승일,김평남 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.2

통풍은 Purine 대사의 이상으로 발생하는 질환으로, 고뇨산혈증인 사람의 전부가 통풍으로 발현되지 않고 증상의 출현 양상이 다양하여 진단과 치료에 주의가 필요하며, 조기에 적절한 조치를 한다면 충분히 조절이 가능한 질환이다. 본대학 내과학교실에서는 통풍으로 치료한 32명의 환자에서 임상양상, 병력과 검사소견을 분석하여 다음과 같음 결과를 얻었다. 1. 32명 모두 남자이며, 최초 발병 시기는 24세에서 72세로 평균 43.8±11.9세이었으며, 30대에서 40대까지가 19명(59.4%)으로 대부분을 차지하였다. 내원 당시 나이는 27세에서 75세까지로 평균 52.3±10.4세였으며, 내원시 까지 평균 유병기간은 8.5±6.8년으로 나타났다. 2. 동반 질환으로는 고지혈증 12례, 신장질환 10례, 고혈압 12례, 비만 8례, 당뇨 2례 등이었다. 3. 이환된 관절은 단관절 침범이 19례(59.4%), 다관절 침범이 13례 이었으며, 최초 이한된 관절은 족무지 중족골지골 관절로 19례(59.4%)로 가장 많았고, 통풍 결절은 20례(62.5%)에서 관찰되었으며, 유병기간이 10년 이상된 12례중 11례 (91.7%)에서 결절이 관찰되었다. 4. 평균 혈중 요산치는 9.17±1.75 ㎎/dl이었으며, 8.0 ㎎/dl에서 9.9 ㎎/dl 사이가 19명으로 전체의 59.4%를 차지하였다. Objective: The gout is a heterogeneous group of diseases resulting from tissue deposition of monosodium urate or uric acid crystals from extracellular fluids supersaturated with respect to this end product of human purine metabolism. The clinical manifestations are such as hyperuricemia, gouty arthritis, gouty nephropathy, uric acid nephrolithiasis. We analyze of clinical manifestations and associated factors in gout. Method: We have reviewed the medical records, radiologic findings and clinical results of thirty-two patients admitted at our department from April 1996 to July 1997. Result: 1) All patients were male. The mean age at initial attack was 43.8 years old, ranging from 24 to 72 years old. 2) The mean level of serum uric acid was 9.17mg/dl on admission. 3) The first metatarsopharyngeal joint was involved in 19 cases (59.4%). Tophus was observed in 20 cases (62.5%). 4) Hyperuricemia was associated with hypertension, obesity, nephrolithiasis and hyperlipidemia.

말초형 간내담관암의 수술 후 예후에 관한 고찰

이종철,이상수,이종균,이규택,최성호,김재준,최규완,백승운,고광철,이풍렬,심상군,류광현,이준혁,박철근,손태성,여규동 대한소화기학회 2000 대한소화기학회지 Vol.36 No.5

Background/Aims: Prognostic factors related to the postoperative survival of patients with peripheral cholangiocarcinoma (PCC) are not well documented. The purpose of this study was to evaluate the clinical and pathologic factors that might influence the postoperative survival of patients with PCC. Methods: Twenty-nine patients with PCC underwent laparotomy between September 1994 and September 1999. Fourteen clinicopathologic factors influencing postoperative survival were analyzed in nineteen patients who underwent hepatic resection (resection group). Ten patients had unresectable advanced tumor (unresectable group). Results: In the resection group, the overall 1-, 2-, and 3-year survival rate was 51.4%, 45.0%, and 28.1%, respectively (median survival of 17.6 months). The median survival in the unresectable group was 4.1 months and no patient lived longer than 1 year. In univariate survival analysis, tumor size and perineural invasion were correlated significantly with overall survival. The survival of patients who underwent resection with positive margin was significantly longer than that of the unresectable group. Conclusions: An aggressive surgical approach provides the best chance for long-term survival of patients with PCC. Tumor size and perineural invasion may be considered as prognostic factors for postoperative survival, but a large, long-term study is needed.

Two component calculations of Pt₂ with relativistic effective core potential including spin-orbit operator

Lee, Dong-Ki,Jeung, Gwang-Hi,Lee, Yoon Sup Wiley Subscription Services, Inc., A Wiley Company 2009 International journal of quantum chemistry Vol.109 No.9

<P>The Kramers restricted two-component ab initio calculations were performed for the eight lowest electronic states of Pt<SUB>2</SUB> using the relativistic effective core potential with the spin-orbit operator at the multireference first-order configuration interaction level of theory employing two-component molecular spinors as one-electron basis. The dominant role of the spin-orbit effects are mainly accounted for by using two-component spinors as one-electron wave function, and the importance of the dynamic and the nondynamic electron correlation effects are shown by employing configuration interaction and coupled cluster methods to obtain reliable spectroscopic data for this molecule. The two-component molecular spinors were generated from Kramers restricted Hartree–Fock calculations for the average configuration and used in the multireference Kramers restricted configuration interaction method to account for nondynamic correlation effect. Effect of dynamic correlations was investigated with the Kramers restricted coupled-cluster (KRCC) method. Spectroscopic constants calculated at the KRCC level are in good agreement with the most recent experimental values. © 2009 Wiley Periodicals, Inc. Int J Quantum Chem, 2009</P>