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      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

        김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

        Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

      • KCI등재
      • 고유동 콘크리트를 이용한 타일 선붙임 시공방법에 관한 기초적 연구

        김우상,김제섭,공민호,박병근,김성식,정상진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

        The objective of this present study is to solve problems in PC tile pre-fixing method using ordinary concrete by adopting the liquefaction method in manufacturing PC to which the tile pre-fixing method is applied, and to provide basic information for the practical use of the PC tile pre-fixing method, which uses high workable concrete, through manufacturing a complex body based on the optimal mix proportion.

      • KCI등재

        뜬 바닥구조용 완충재의 동탄성계수 측정에 관한 연구

        김하근,김명준,이병권 대한건축학회 2005 대한건축학회논문집 Vol.21 No.1

        The aim of this study is to suggest the method of measuring the dynamic stiffness and the loss factor of materials used under floating floors in dwellings by Korea standard (KS F 2868) We measured and compared those of 18 resilient materials in several conditions such as the size of test specimens, the type of excitation methods, pick-up locations and so on in the first result, there's no differences of natural frequency according to vibration pick-up location in the second result, the dynamic stiffness by using sinusoidal signal of exciter is higher than that by using impulse signal of Impact hammer Finally, in case of measuring dynamic stiffness of material which has higher stiffness or is easy to change by bending moment, It should be measured with great care

      • 사람 정자의 성숙도와 운동성에 따른 세포질내 정자주입 후 전핵형성과 초기 배발생

        이상찬,김종흥,김병기,김근주 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

        In the present study, we investigated the effect of maturity and motility of spermatozoa on the formation of pronucleus and subsequent developmental capacity of the human embryo in vitro. The fertilization was performed by means of intracytoplasmic sperm injection (ICSI) in HEPES-buffered m-TCM-199 medium. In the first part of the experiment, motile or immotile human spermatozoa ejaculated were injected into cumulus-enclosed human oocytes matured in vivo. Significantly(P$lt;0.002)higher proportion of oocytes that was injected with motile spermatozoa formed 2 pronuclei than the oocytes injected with immotile spermatozoa(79.8% vs 51.7%). In the second part of the experiment, cumulus-enclosed human oocytes matured in vivo were injected with motile or immotile spermatozoa collected from testes. There was no difference between motile and immotile spermatozoa. In the third part of the experiment, using modified Tyrode's medium containing 10.0 mM lactate, 0.5 mM pyruvate, 0.2 mM taurine, 1.0 mM glutamine, 2.22 mM MEM amino acids, vitamin and 10% human follicular fluid, we found that development of oocytes that formed 2 pronuclei were able to develop to 9-16 cells regardless of maturity and motility of spermatozoa.

      • KCI등재

        정신분열병과 N-Methyl-D-Aspartate 수용체 유전자와 연관된 VNTR 표지자인 D9S158 다형성의 연합

        김종원,채영규,정은기,김길숙,박강규,이영호,최인근,양병환,한진희 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.5

        정신분열병과 NMDA 수용체와 연관된 D9S158 유전적 표지자와의 연관성을 알아보기 위해 75명의 정신분열병 환자군과 87명의 정상대조군을 대상으로 중합효소연쇄반응을 이용하여 연합연구를 시행하여 다음과 같은 결론을 얻었다. D9S158 유전좌위에는 모두 8개의 대립유전자가 있었고, 각 대립유전자는 cytosine-adenine염기가 반복되는 217염기쌍에서 233염기쌍의 형태였다. 먼저 정신분열병 환자와 정상대조군의 대립유전자의 빈도를 비교해 본 결과 통계적으로 유의한 차이를 보이지 않았다(p〉.05). 환자군을 좀 더 동질적으로 만들기 위해 정신분열병의 가족력 유무, 음성 및 양성증상, 연성신경학적 징후, DSM-IV 임상아형에 따라 환자군을 나누어 대립유전자의 빈도를 비교해 본 결과, 특정 임상양상과 관련이 있는 대립유전자를 발견하지 못하였다. 결론적으로 본 연구에서는 D9S158 유전좌위와 정신분열병의 연관성을 입증하지 못하였으나 NMDA 수용체 유전자주위의 다른 표지자나 좀 더 유전적으로 동질한 환자군을 대상으로 한 추후연구가 필요할 것으로 생각된다. An association study with Korean schizophrenic patients(N=75) and normal controls(N=87) was performed to find the relationship between D9S158 polymorphism and schizophrenia using polymerase chain reaction. Eight different alleles of a dinucleotide polymorphism on D9S158 locus were observed in both group. When we compared the frequencies of alleles between schizophrenics and normal controls, there was no significant difference between two groups. To increase homogeneity of schizophrenic group, we divided schizophrenic group by clinical phenotypes such as family history, negative and positive symptoms(PANSS), soft neurologic signs(NES-K) and DSM-IV diagnostic subtypes. Then we compared the frequencies of alleles among subgroups of clinical phenotypes, and there were no significant differences between subgroups(p〉.05). Although our findings fail to provide an evidence of association between schizophrenia and D9S158 locus, further investigation of other loci that are linked to NMDA receptor gene may be needed in genetically homogeneous subgroups of schizophrenia.

      • 양생방법에 따른 타일 선붙임 공법의 접착특성에 관한 실험적 연구

        김우상,공민호,안무영,박병근,김성식,정상진 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        The objectives of the present study is to solve problems in PC tile before-fixing method using ordinary concrete by adopting the liquefaction method in manufacturing PC to which the tile before-fixing method is applied, and to provide basic information for the practical use of the PC tile before-fixing method, which uses high workable concrete, through manufacturing a complex body based on the optimal mix proportion.

      • 기-액계면 흡착에 의한 계면활성제 및 중금속분리

        이근희,남상진,김병조,박경기,박종태,신정호 釜山大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.53 No.-

        CTAB에 의한 CuS 침전 미립자의 응집과 기포 흡착특성을 고찰하였다. CTAB의 기포흡착은 Langmuir흡착식을 따르며, 포말간 본체액의 동반을 고려한 회분해석으로부터 구한 흡착열은 3700cal/mol로 나타났다. CTAB에 의한 CuS미립자의 기포흡착은 기포-입자간 충돌흡착으로 설명되었고, 흡착분리에 대한 최적 농도비는 CuS의 최적 응집농도비와 일치하였으며, 그 값은 [CTAB] 대 [CuS]가 0.1로 얻어졌다. 기포에 의한 포집효율은 pH와 CTAB농도 등에 의존하나 공기의 유량에는 무관하였으며, 최대 포집효율은 최적 첨가농도에서 0.0002로 나타났다. 또한 Cu-Cd-Zn 황화물의 혼합계에서 CTAB를 사용한 기포흡착의 경우 ZnS의 선택적 분리가 가능하였다. The characteristics of the bubble adsorptive separation of CTAB(cetyltrimethyl- ammonium bromide) and CuS precipitates was investigated. The Langmuir adsorption equation was adequate at very low concentration of CTAB, and the adsorption heat was determined from the batch analysis considering the bulk liquid accompanied between bubbles. The adsorption mechanism was explained with the collision adsorption between bubbles and precipitate particles. The optimum concentration ratio of [CTAB] to [CuS] for adsorptive separation was 0.1 and coincided with the ratio for the coagulation of particles. The collection efficiency was depended on pH and CTAB concentration but not the air flow rate, and the maximum efficiency was 0.0002. The selective separation of ZnS from the mixture of Cu-Cd-Zn sulfides was able by the bubble adsorption with CTAB.

      • 에너지법을 이용한 2경간 연속곡선보의 해석

        서상근,김은수,장병순 부산대학교 생산기술연구소 2000 生産技術硏究所論文集 Vol.59 No.-

        최근 고속도로 교량이나 입체교차로등에 평면곡선보의 사용이 증가하고 있다. 구조적인 복잡함 때문에 곡선교는 휨응력 뿐만아니라 비틀림응력까지 받게 된다. 통상적으로, 곡선교는 휨비틂이론으로 해석되는데 곡선교의 해석에는 ��綢늣염倖�무시한 보이론과 ��綢늣염倖�고려한 보이론이 있다. 본 논문에서는 ��綢늣염倖�고려한 휨비틈이론에 기초를 두고 단순지지 곡선보의 단면력과 변위를 결정하고 에너지법을 사용하여 2경간 연속 곡선보에 대한 탄성방정식을 유도하였다. 또한 실하중을 받고 있는 2경간 연속 곡선보의 단면력과 변위를 구하였다. The use of horizontally curved girder bridge has increased considerably for highway bridge and interchanges. Due to the geometric complexities, curved girder are subjected to not only flexural stresses but also significant torsional stresses. Usually, a curved girder is analyzed by the flexural torsional theory. There are several theories which are available for the analysis for the curved girders ; beam theory ignoring the warping-torsional effects and beam theory considering the warping torsional effects. In this paper, the stress resultants and displacements of simply supported curved girder based on the flexural torsional theory considering torsional warping effects are determined. And elastic equations of two-span continuous curved girder are obtained by using energy method. Also, bending moment diagram, warping moment diagram, torsional moment diagram, shearing force diagram, and deflection diagram of two-span continuous curved girder bridge applying vertical loads and uniform loads are presented.

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