대동맥 협착증과 동반된 출혈성 위장관 동정맥 기형에서 Estrogen-Progesterone 치료 1예

김도연,김화정,김효정,남준식,박수영,박영미,신정은,주미순,황민규,정혜경,손혜영,이선영,이한주 大韓消化器內視鏡學會 1999 Clinical Endoscopy Vol.19 No.부록2

消石灰處理가 볏짚의 粗成分 및 消化率에 미치는 影響에 관한 硏究

辛炯泰,魏筍英,金永玉 成均館大學校 1981 論文集 Vol.29 No.-

Nylon bag dry matter digestibility (NBDMD, %), nylon bag organic matter digestibility (NBDMD, %) and chemical compositions were analysed to evaluate the nutritive values of 5 varieties of Ca(OH)_2-treated rice straws (Akibare, Tongil, Milyang 23, Yooshin and Suwon 264) by using Korean native male goats. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9×14 ㎠ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 72 hours. They were washed, dried in an oven at 105℃ for 24 hours and weighed "NBDMD" (%) and ashed in an muffle furnace at 600℃ for 2 hours and weighed "NBOMD" (%). The results which were obtained with this experiment were as follows : 1. Nylon bag dry matter digestibility (NBDMD, %) and nylon bag organic matter digestibility (NBOMD, %) of Ca(OH)_2-treated rice straws were highly significant different (p<0.01) in different levels of Ca(OH)_2 treatment and of different varieties of rice straws. 2. The relationship between total mean NBDMD (%, Y_1) of 5 varieties of rice straws and Ca (OH)_2 concentration (%, X) at 72 hours rumen incubation was : Y_1=1.51X+41.36 (r=0.97^**) 3. The relationship between total mean NBOMD (%, Y_2) of 5 varieties of rice straws and Ca(OH)_2 concentration (%, X) at 72 hours rumen incubation was : Y_2=1.36X+41.02 (r=0.95^**) 4. The orders of NBDMD (%) and NBOMD (%) for 5 varieties of rice straws were Yooshin, Suwon 264, Milyang 23, Tongil and Akibare, and Yooshin showed the highest values and Akibare showed the lowest values. Crude fiber, cell-wall constituents and lignin percent in the five varieties of rice straws were shown the negative relation to the NBDMD (%) and NBOMD (%).

폐분체 도료의 재활용 방안에 관한 연구

신동철,김영훈,이순기,김경원,신선명,강헌찬 동아대학교 환경문제연구소 1999 硏究報告 Vol.22 No.1

With the progress of industry, the much more demand of paint around us grows rapidly. However, the whole quantity of raw materials used to make powder coatings is presently imported to fill the domestic needs. Moreover, it is well known that the waste powder coatings from the domestic industries are mostly incinerated. The method of destructing the waste powder coatings by fire causes VOC to be generated, and this results in some serious environmental problems such as air pollution and so on. Therefore, the effective and proper measure must be devised to reuse the waste powder coatings for the purpose of eliminating waste of resources and avoiding the outflow of foreign currency. This study aims to make the plan to recycle the waste powder coatings, and its conclusion is drawn as follows: First, it can be seen that the waste powder coatings with a weak electrostatic power restore gradually to the original state of electrostatic power through the process of fusion and retreatment. Second, it can be estimated that those coatings, with the use of the cyclon, can be removed by dividing a powder of particles less than 10㎛. Third, it can be ascertained that the possibility of reusing the waste powder coatings is proved when it is divided into particles by cyclon and a revolving screen after the process of fusion, rolling, crushing and pulverization.

달맞이꽃(Oenothera odorata Jacquin) 뿌리에서 추출한 항균성분의 특성

신성진,권순경,이권행,성낙도,최우영 충남대학교 농업과학연구소 1994 농업과학연구 Vol.21 No.1

An antibacterial component was isolated from the roots of evening primrose (Oenothera odorata Jacquin). The component was purified by repeated preparative TLC of the chloroform-extract with solvent system of toluene(7): ethyl acetate(4) : formic acid(O.8). NMR spectrum indicated that it is a steroid compound containing radical(-C=C-C=0) and aromatic structures. Its antibacterial activity against strains of the genus Streptococcus was relatively high, the MIC value was 50 according to the Hoechst Manual-345, as compared with the other genera such as Staphylococcus and Escherichia.

苛性소다 處理가 볏짚의 나이론주머니 消化率에 미치는 영향

辛炯泰,金永玉,魏筍英 成均館大學校 1980 論文集 Vol.28 No.-

Four Korean native male goats, weighing approximately 30㎏ each, were equipped with rumen cannulas to study the effect of different levels of NaOH treatment, of rumen incubation time and of different kinds on "nylon bag dry matter digestibility (NBDMD,%)" and "nylon bag organic matter digestibility (NBOMD,%)" of rice straws. The goat was housed individually in pen and was fed 600 grams (concentrate) daily, and fed rice straw and rincal blocks ad libiltum. Three grams of dried samples by grinding with 2.45㎜ Wiley mill screen were put into a bag 9 X 14 ㎝ made of 100 mesh nylon. These bags were put into the ventral sac of the rumen and taken out at the end of 24, 48 and 72 hours (Experiment 1) and 72 hours only (Experiment 2). They were washed, dried in an oven at 105℃ for 24 hours and weighed "NBDMD", and ashed in an muffle furnance at 600℃ for 2 hours and weighed "NBOMD". The results which were obtained with two experiments were as follows; 1. Nylon bag dry matter digestibility (NBDMD,%) and nylon bag organic matter digestibility (NBOMD,%) of NaOH treated straws were highly significant different (P<0.01) in different levels of NaOH treatment, of rumen incubation time and of different kinds of rice straws. 2. The relationship between mean NBDMD (%, Y_1) of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hours rumen incubation was: Y_1=2.93X_1+42.32(r=0.97^**) 3. The relationship between mean NBOMD (%, Y_2)of 5 kinds of rice straws and NaOH concentration (%, X_1) at 72 hour rumen incubation was: Y_2=2.76X_1+41.32(r=0.96^**) 4. The orders of NBDMD (%) and NBOMD (%) for 5 kinds fo rice straws were Yooshin, Suwon 264, Milyang 23, Tongil and Akibre. Therefoare it is necessary to study more on the utilization of NaOH-treated new-bred rice straws for animal performance than old-bred rice straw as Akibare. 5. The optimal level of NaOH (%) for improving NBDMD and NBOMD from 5 kinds of rice straw on the basis of Dr. McCullough's theory was as follow: 6% NaOH for Yooshin, Suwon 264 and Milyang 23; 7% NaOH for Tongil and 8% NaOH for Akibare. 6. Crude protein, crude fiber, ADF, cellulose, lignin percent of 5 rice straws did not much different by chemical analysis. The orders of NBDMD (%) and NBOMD (%) for 5 kinds of rice straws did not same orders of the consitituents of chemical composition in rice straws.

古代의 韓ㆍ中ㆍ日 醫藥交流 : 「일본서기」를 중심으로 indicated in 「Ilbonseogi」

신순식,최환수,양영준,홍원식 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

『Ilbonseogi』(edited A.D.720) was studied to investigate the medical and pharmaceutical exchange among ancient Korea, China and Japan. It seemed that Korean and Chinese traditional medicine was introduced to Japan through Korea. It was also shown in 『Ilbonseogi』 that Koreans who lived in China and Japan during that time seemed to have active medical idea exchange. From various facts indicated in 『Ilbonseogi』, it was believed that Korean and Chinese traditional medicine was the basis for the foundation of Japanese traditional medicine.

소아청소년기에 치수치료를 받은 제1대구치의 술전 상태 조사

이순영,이경호,노홍석,정태성,김신 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

제1대구치는 막중한 역할을 함에도 불구하고, 청소년 이전에 건강을 상실하는 경우가 드물지 않다. 본 연구는 청소년기 이 전에 치수치료를 받게 된 제1대구치의 우식 및 수복 상태와 분포를 파악할 목적으로 시도되었다. 최근 5년간 부산대학교 치 과병원에서 치수치료를 받은 18세 이하 106명 환자의 135개 제1대구치를 대상으로 의무기록에 대한 조사를 시행하여 다음 과 같은 결과를 얻었다. 1. 평균 연령은 11.9세(남 11.5세, 여 12.5세)였고 유의한 성차를 보였으며(p<0.05), 악별로는 상악 47개, 하악 88개로 하악 치아가 더 많았다. 2. 치수 치료 전 치료 기왕력이 없는 치아는 74개, 치수 또는 수복 치료를 받은 치아는 61개였다. 그 중 재치수치료를 받게 된 경우는 22개로 치수절제술-치수절단술의 순이었으며, 단순 수복치료를 받았던 치아는 39개로 복합레진-아말감-GI- 인레이-수복물 탈락 후 미치료-열구전색 및 주조 전장관의 순이었다. 3. 병소 위치가 분류 가능한 73개의 병소 중에서는 근심면 병소가 22개, 교합면 혹은 협설면 병소 39개, 원심면 병소가 12 개를 차지하였다. In clinical dentistry, it is not difficult to meet the permanent first molars with severe coronal caries lesions in children or adolescents. The circumstances surrounding the first molars of children and adolescents are so immature and imperfect compared with those of adults. So we thought it significant to understand the status of these teeth at the moment of endodontic treatment and immediate cause of it. 106 patients with 135 permanent molars necessitating endodontic treatment in childhood and adolescence were included in this study, and the dental records and radiographs were examined. 1. The mean age was 11.9 year (male 11.5, female 12.5) and the result shows significant difference between gender(p<0.05). The mandibular teeth took more than half percentage than maxillary teeth. 2. Of 135 teeth, 45.2 percent of teeth had history of dental treatment previously and 16.3 percent of teeth showed necessity of re-endodontic treatment. 3. Of 73 teeth, 22 teeth had mesial-wall cavity causing endodontic treatment, 39 had occlusal cavity, and 12 had distal cavity.

부착단백질이 사람 치수세포의 부착 및 증식에 미치는 영향에 관한 연구

신영주,최호영,민병순,박상진,최기운 慶熙大學校 齒科大學 1995 慶熙齒大論文集 Vol.17 No.2

The purpose of this vitro study was to evaluate attachment and proliferation of human pulpal cells to the attachment glycoprotein-coated and non-coated culture dishes. Well known adhesive glycoproteins were used, such as type I collagen, type IV collagen, fibronectin, laminin, and vitronectin. Each adhesive glycoproteins applied onto the culture dishes. In this study, the protein coated and non-coated dishes were classified as each groups. Human pulpal cells cultured onto each culture dishes. After 90 minute, 4 hour and 24 hour incubation attached cells in each group were counted with hematocytometer for evaluation of the attachment of human pulpal cells. The configurations of attached human pulpal cells were done by SEM observation. The results as follows 1. After 90 minute incubation the score of attachment of human pulpal cells was best in laminin-coated group among groups. Then fibronectin, type IV collagen group were better, and allproteins were higher than control. 2. After 4 hour incubation the numbers of attachment of human pulpal cells were most in fibronectin coated group. 3. After 24 hour incubation all of adhesive glycoproteins showed high and similar attachment effect to human pulpal cells. 4. In SEM observation, fibronectin and type IV collagen groups showed well spreaded human pulpal cells, then laminin group was moderately spreaded, and vitronectin group was mildly spreaded as well as control group.

광주광역시 치매의 유병률과 위험인자의 도시-농촌 지역 비교

신일선,김재민,윤진상,김석재,양수진,김웅장,이승현,강순아,곽지영,이형영 大韓神經精神醫學會 2002 신경정신의학 Vol.41 No.6

연구목적 : 본 연구의 목적은 광주광역시의 도시 및 농촌 지역에 거주하는 노인에서 치매의 유병률과 위험인자를 조사하고자 하였다. 부가적으로 이 두 지역간에 치매의 유병률과 위험인자를 비교하고자 하였다. 방 법 : 광주광역시의 전형적인 도시와 농촌지역의 65세 이상의 노인(N=1,598)을 대상으로, 2단계의 역학연구를 수행하였다. 1차 선별 단계에서는 38명의 훈련된 연구보조원이 대상노인을 면담하여, 사회인구학적 특징을 조사하고 한국판 간이정신상태검사(Korean version of Mini-Mental State Examination ; MMSE-K)로 평가하였다. 2차 임상 진단 단계에서는 1차 단계에서 MMSE-K 점수가 24점 이하인 노인(N=431)을 대상으로, 전문연구팀의 임상적 평가를 통해 치매를 진단하고 원인질환별로 알쯔하이머병(Alzheimer's disease ; AD), 혈관성 치매(vascular dementia ; VaD) 및 기타 치매로 분류하였다. 대상노인에서 치매의 유병률을 측정한 후, 광주광역시 전체 노인의 연령보정 유병률을 산출하였다. 전체 대상에서 AD의 위험인자를 조사한 후, 도시와 농촌군으로 나누어 분석을 다시 시행하였다. 결 과 : 1차 및 2차 단계의 참가율은 각각 71.0%(N=1,134) 및 83.2%(N=410) 였다. 연구 참여 노인(N=1,134)에서 전체 치매, AD 및 VaD의 유병률은 최소 각각 9.7%, 5.2%, 1.8%였다. 광주광역시 전체 노인의 연령 보정 유병률은 각각 10.7%, 5.7%, 1.9%인 것으로 산출되었다. AD의 독립 위험인자는 고령, 여성, 무학이었다. 도시와 농촌에 따른 유병률의 차이는 파악되지 않았다. 그러나 AD의 위험인자는 지역에 따라 차이가 있었다. 도시 노인에게는 무학만이, 농촌 노인에게는 고령과 여성인 경우가 독립 위험인자였다. 결 론 : 광주광역시 노인에서 치매의 유병률은 높았고, 이는 국내 다른 지역에서 수행된 선행연구 결과와 유사하였다. 알쯔하이머형 치매의 위험인자는 도시와 농촌에 따라 다른 결과를 보였다. 본 연구 결과는 한국에서의 치매의 실태를 반영하며, 치매의 적절한 관리와 예방을 위해서는 지역성 특성이 고려되어야 함을 시사한다. Objectives : The purpose of this study was to investigate the prevalence rate and risk factors of dementia in an urban and a rural sample of older persons in the metropolitan Kwangju area, Republic of Korea. In addition, the prevalence rate and risk factors of dementia between the two samples were compared. Methods : A two-phase epidemiological study of residents aged 65 or over(N=1,598) was conducted in a highly developed, urban and a non-contiguous, poorly developed, rural area of metropolitan Kwangju. In the first(screening) phase, 38 trained research assistants collectively peformed in-home interviews for all participants. Detailed sociodemographic characteristics were gathered and the Korean version of Mini-Mental State Examination (MMSE-K) was administered. In the second (diagnosing) phase, diagnosis of dementia was established for those scoring 24 or less on the MMSE-K in the screening phase(N=431), and etiological types of dementia were classified to Alzheimer's disease(AD), vascular dementia(VaD) or miscellanous type by two teams of experts. Prevalence rate of dementia was determined in the participants, and age-standardized prevalence rate adjusted by age distribution in metropolitan Kwangju was estimated. For AD, the risk factors were investigated in all participants, and analyses were repeated for the urban and rural samples separately. Results : The participating rates in the first and second phases were 71.0%(N=1,134) and 83.2%(N=410), respectively. In the participants, the prevalence rates of dementia(all types), AD and VaD were 9.7%, 5.2% and 1.8%, respectively. The age-standardized prevalence rates were 10.7%, 5.7% and 1.9%, respectively. Aging, female gender and no education(complete lack of formal education) were identified as independent risk factors for AD. No difference between the urban and rural samples was observed in the prevalence rates of dementia(all types), AD and YaD. However, risk factors for AD differed between these areas. In the urban sample, no education was the only significant factor ; whereas, aging and female gender were identified as risk factors in the rural sample. Conclusion : A high prevalence rate of dementia was observed among old persons in metropolitan Kwangju, consistent with previous studies conducted in other Korean areas. The risk factor profi1es for AD differed between urban and rural settings. The results of this study reflect the current status of dementia in Korea and suggests that appropriate management and prevention strategies for dementia should be tailored toward the geographic settings.

인체장염유발 Campylobacter jejuni의 생육특성 및 Polymerase Chain Reaction에 의한 신속 검출

신순영 서울여자대학교 대학원 1999 論文集 Vol.- No.7

인체 장열유발균인 Campylobacter jejuni의 식품으로의 오염방지와 그 검출을 위하여 순수 배양조건과 우유, 닭고기 등의 식품에 균을 접종하여 그 생육을 온도 별로 관찰하고 그 검출을 위한 polymerase chain reaction을 시도하였다. Campylobacter jejuni는 최적온도 42℃나 저온 5℃에서 보다 오히려 25℃ 상온에서 사멸이 빨랐다. Polymerase chain reaction은 16S rRNA 유전자에 근거한 primer, pA와 pB를 이용하여 whole cell을 DNA 추출없이 직접 DNA templete로 이용하였으며, 이 때 Campylobacter jejuni의 검출 감도는 1PCR 반응당 균수 1-10¹이었다. 이 감도는 순수 배양액에서나 우유 혹은 닭고기 등의 식품에서도 거의 같은 수준으로 유지되었다. 이러한 결과는 polymerase chain reaction을 이용한 Campylobacter jejuni의 식품으로 부터의 적용에 있어서 실용 가능성을 제시하였다. The provide more information on the enteric pathogen Campylobacter jejuni in the view of food sanitation, survival characteristics of two strains of C. jejuni and the polymserase chain reaction(PCR) with pA and pB pair based on the 16S rRNA gene for the sensitive and specific detection in the different conditions were investigated. When 10? Or 10³ per mL of C. jejuni cells were inoculated in the supplemented Brucella broth and kept at 42℃, 25℃ and 5℃ under the static aerobic condition for 7 days, organisms exponentially proliferated to a>10?, even in the 10³ per mL inoculated-sample at 42℃ for 1-2 days and the considerable level of viability maintained during 7 days. At 5℃, most of the initial level of organisms survived at the early period and only a < 0.5-log? Cells decreased during the 7 days. At 25℃, a remarkable number of C. jejuni declined within 1-2 days and showed undetectable level of cells after 4 days. The results suggest that C. jejuni contaminated to food can survive at the refrigeration temperature whereas they are sensitive at the room temperature. For the application of PCR, six oligonucleotides were utilized in an amplification experiment and PCR products of predicted sizes were generated from whole cells and boiled cell lysates at the same intensity. In the PCR using the pA and pB primer pair, the detection limit of C. jejuni was the level of 10¹ bacteria cells or less in both the pure culture and milk and chicken enrichment samples. The PCR method using a primer pA and pB was repeatable and specific for the detection of C. jejuni in food. It is suggested that PCR is a very potential method to detect C. jejuni which causes disease with low number of cells in food.