췌장염에 의한 가성낭종내에 생긴 가성동맥류 : 1례 보고

오연희,이채경,김승현,이성우,양창현,이정호,이영현 동국대학교 경주대학 1996 東國論集 Vol.15 No.-

만성 췌장염의 합병증으로 생긴 가성동맥류는 드문질환으로, 반복적으로 다량의 출혈을 일으킬 수 있으며, 치료를 하지 않을 경우 사망율이 높기 때문에, 조기 진단과 치료가 필수적이다. 저자들은 38세 남자 환자에서 췌장염의 합병증으로 생긴 가성낭종내에서 발생한 가성동맥류 1예를 경험하였기에 보고하는 바이다. 가성 동맥류의 색혈류도플러상 낭종내에 양방향 흐름의 와류를 볼 수 있었다. Pancreatic Pseudoaneurysm within Pseudocyst from Pancreatitis: 1 Case Department of Diagnostic Radiology and Internal Medicine, College of Medicine,DongGuk University Yeon Hee OH M.D., Chae Kyeong Lee M.D., Seoung Hyeon Kim M.D., Sung Woo Lee M.D., Chang Heon Yang M.D., Jung Ho Lee M.D., Young Hyun Lee M.D. Pseudoaneurysm from pancreatitis is uncommon, but it can cause recurrent and massive hemorrhage. Because of high morbidity and mortality, early detection and treatment of the pseudoaneurysm is needed. We report a case of pseudoaneurysm within pseudocyst from pancreatitis. Color-flow Doppler sonography shows bidirectional flow and turbulent arterial flow, within anechoic mass.

발열을 동반한 호중구감소증에서 Cefepime 단독투여와 Ceftazidime 및 Tobramycin 병합투여의 효능비교

정현욱,채제욱,강미라,양정채,문치숙,기현균,장현하,오원섭,김기현,백경란,이남용,송재훈 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 국내에서 발열을 동반한 호중구감소증이 있는 악성 종양환자에게 경험적 항생제로 베타락탐계 항생제와 아미노배당체의 병합요법의 사용이 일반적이다. Cefepime은 광범위 항균 작용을 가지고 있어, 그람 음성균 뿐만 아니라 그람 양성균에 대해서도 우수한 효과를 나타낸다. 재료 및 방법: 발열을 동반한 호중구감소증이 있는 악성 종양환자를 대상으로 무작위, 공개, 비교 연구를 시행하였다. 대상 환자를 무작위로 cefepime 단독요법군과 ceftazidime 및 tobramycin 병합요법군으로 나누어 투여하고 각각의 임상적 효능과 안전성을 비교하였다. 구강및 인후 점막염이 있는 환자에서 분리된 녹색 연쇄알 구균에 대한 항생제 내성 정도를 조사하였다. 결과 : 대상환자 89명 중 CA 투여군이 48예(53.9%), CT 투여군이 41예(46.1%)이었다. 발열의 유형별로 MDI는 18예(20.2%), CDI는 9예(10.1%), UF는 62예(69.7%)로 두 군 간에 차이가 없었다. CA 투여군과 CT 투여군의 임상적 호전률은 시험약 투여 후 2-4일째 각각 91.7%, 85.4% (P=0.31), 치료 종료 시 각각 91.7%, 100% (P=0.15)로 두 군간에 유의한 차이가 없었다. 치료 종료 시 CA 투여군과 CT 투여군의 세균학적 소실률은 모두 100%로 두 군간의 유의한 차이가 없었다(P=0.78). 점막염이 있는 환자로부터 녹색 연쇄알 구균이 분리된 경우는 25예(28.1%)이었으며, 분리된 녹색 연쇄알 구균은 penicillin, ceftriaxone, cefepime, vancomycin에 모두 감수성을 보였다. 약제 관련 이상 반응의 발생 빈도도 두 군간에 유의한 차이가 없었다. 결론 : 발열을 동반한 호중구감소증이 있는 악성 종양환자의 경험적 항생제로서 cefepime 단독요법은 ceftazidime 및 아미노배당체의 병합요법만큼 효과적이고 안전하였다. Background : Broad-spectrum antibiotic therapy has been recommended as an empirical regimen in cancer patients with febrile neutropenia. Cefepime is a fourth generation cephalosporin with good activity against both gram-positive cocci and gram-negative bacilli. Materials and Methods : To compare the efficacy and safety of cefepime alone with ceftazidime plus tobramycin as empirical regimen for adult cancer patients with febrile neutropenia, a randomized, open label, comparative trial was performed. If the patient showed clinical improvent 72 hours, antibiotic could be changed to oral ciprofloxacin. Clinical and microbiological responses were determined at 72 hours and at the end of therapy. To investigate the antimicrobial resistance of viridans streptococci, swab cultures were obtained from throat in all enrolled patients and antimicrobial susceptibility tests were performed by using microdilution method according to the NCCLS. Results : A total of 89 patients were enrolled. Forty-eight patients received cefepime alone (CA), and 41 patients received ceftazidime plus tobramycin (CT). Demographic and baseline clinical characteristics were similar in both groups (P>0.05). The initial clinical success rate at day 2-4 in group CA (91.7%) was similar with that in CT group (85.4%) (P=0.31). At the end of therapy, the final clinical success rate in CA group (91.7%) was similar to that in CT group (100%) (P=0.15). In 18 patients, with microbiologically defined infections, the eradication rate was 100% in both groups. Adverse events including liver dysfunction (21.3%) and renal dysfunction (2.2%), were similar in both groups (P=0.87). Viridans streptococci were isolated from the throat cultures in 25 cases, and all of these strains were susceptible to penicillin (MIC_(90) 0.12 ㎍/mL), cefepime (1 ㎍/mL), and vancomycin (0.12 ㎍/mL). Conclusion : Efficacy and safety of cefepime monotherapy was comparable to the combination of ceftazidime and tobramycin. It could be used as an alternative empirical regimen for treating cancer patients with febrile neutropenia.

노인의 영적 간호요구

최미혜,김경희,김귀옥,김기숙,김수강,김정신,김춘숙,노흥진,박지연,성혜연,오명선,이선희,이원옥,이윤영,이현수,장명재,차혜경,채정선,홍상희 중앙대학교 의과대학 간호학과 간호과학연구소 2001 중앙간호논문집 Vol.5 No.1

This study was designed to exam the aged's needs for spiritual nursing care. The purpose was to serve as a basis for the development of spiritual nursing practice. The major findings are as follows : 1. The degree of needs for spiritual nursing care as area was that needs of love and relationship mean 22.0, needs of meaning and object mean 28.2, needs of forgiving mean 13.5. Total needs for spiritual nursing care mean 63.7, which was on the upper middle level. The needs of meaning and object was rated highest. 2. Among the general characteristics of the subjects, needs of love and relatiohship wasn't significanlty different. 3. Among the general characteristics of the subjects, needs of meaning and object was significantly different according to two factors : age(F=7.260, p=0.001), religion(F=5.275, p=0.001). Higher needs of meaning and object was possessed by the older than the younger, by the one who have religion than the other. 4. Among the general characteristics of the subjects, four factors made a significantly difference to needs of forgiving : sex(t=-2.851, p=0.006), age(F=8.201, p=0.001), religion(F=6.928, p=0.000), disease(t=2.327, p=0.024). Higher needs of forgiving was possessed by man than woman, by the older than the younger, by the one who have religion than the other, by the one who have disease than the other.

핵산 내성세균 Micrococcus sp. BCNU121의 생리적 특성에 관한 연구

이현채,주우홍 昌原大學校 基礎科學硏究所 1997 基礎科學硏究所論文集 Vol.9 No.-

The strain BCNU121 among the isolated strains is hexane-tolerant Gram-positive coccus. This strain showed catalase positive, oxidase negative and arginine dihydrolase positive reaction, and formed the cluster of cells. Also this strain hydrolyzed gelatin and grew at nutrient agar with 7.5% NaCl. On the basis of the above date, this strain BCNU121 have been identified as Micrococcus sp. The optimal condition for growth was determined.

갑상선기능저하증에 기인한 내인성 급사 1예 보고

이정규,전지현,김민정,이규재,김한겸,조현득,채양석 大韓法醫學會 1999 대한법의학회지 Vol.23 No.2

Although it is known that hypothyroidism can cause cardiac dysfunction, it is very hard to find a case report on sudden death due to hypothyroidism. There are only two reported cases on mediline; one is about a 15-year-old girl who died suddenly of Hashimoto's thyroiditis and the other is about a 31-year-old man who also died suddenly of hypothyroidism associated with chronic lymphocytic thyroiditis. Recently we found a young woman who unexpectedly died while she was sleeping. She was diagnosed as hypothyroidism when she went to hospital about a month before she died. At autopsy there were roughly four abnormal findings; Hashimoto's thyroiditis, mild chronic active hepatitis, diverticulosis and accessory spleen. Trace of chlorpheniramine was detected in gastric remains and blood alcohol level was 0.37 percent. To our knowledge, this is the first case reporting sudden and unexpected natural death associated with hypothyroidism in Korea.

Double scanning 방식을 적용한 X-ray video converter 개발

이채욱,문병현,오신범 大邱大學校 科學技術硏究所 1999 科學技術硏究 Vol.6 No.1

With the rapid development of medical technology, the digital radiological imaging techniques, such as CT, MRI, PET, CR and X-ray, have been widely used. The demand of medical image storage and noiseless signal requires good video converter system. In this paper we develop a new x-ray video converter using double sunning method. This converter can simplify the monitoring system and improve the image enhancement.

실험적으로 유도된 이독성 난청에서의 Ginkgo Extract의 효과

이상흔,조영채,도현우,강현욱,조태환 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

이독성 난청에서의 Ginkgo extract의 효과를 보고자 기닉픽 22마리를 대상으로 이음향방사를 측정하여 난청군과 치료군을 비교 검토한 바 성적을 요약하면 다음과 같다. 난청군에서의 DP-OAE는 대군조에 비해 전 주파수에서 감소 내지 소실을 보였으며4KHz 에서만 선택적으로 큰 감소를 나타낸것도 있었다. Ginkgo estract로 예방 치료한 군에서는 난청군에 비해 DP-OAE가 현저하게 출현 하였으며 정상 DP-OAE소견을 나타낸 것도 있었다. 난청치료군에서도 난청군에 비해 전체적으로 DP-OAE 가높게 출현되고 있었다. 이상의 소견으로 보아 Ginkgo estract가 이독성 난청과 감각신경성 난청에서의 예방 및 치료 효과의 가능성을 제시해 준다고 생각되는 바이다. This study was designed to investigate the effect of Ginkgo biloba extract on the kanamycin induced ototxicity in inner ears 22 guinea pigs. The animals were divied into 4 groups. In ototoxic group, kanamycin was injected 400mg/kg per day for 7 to 10 days. In preventive treated group, kanamycin with same dose and Ginkgo biloba extract(50mg/kg)were simultaneously injected daily for same duration. In post treated toup, Ginkgo extract was treated for 15 days in kanamycin injected group. The Preyer's reflex and DP-OAE (distortion product otoacoustic emissions) were used for the monitoring of hearing changes. In the ototoxic group, the amplitude of DP-OAE was marked decreased or disappeared in all test frequencies or 4KHz only. The Preyer's reflex was disappeared in all ototoxic group. In the preventive treated group with Ginkgo extract, normal DP-OAE or slightly decreased DP-OAE in 4 KHz was noticed. This finding was seemed to be similar to the post-treated group. From the above results, Ginkgo extract is suggested to have beneficial effects for the management of ototoxicity and sensorineural hearing loss.

유성견에서 periodontal distraction에 의한 급속 치아견인 시 치수 및 치주조직의 변화에 관한 연구

이종진,홍현실,채종문,조진형,김상철 대한치과교정학회 2007 대한치과교정학회지 Vol.37 No.5

유성견에서 periodontal distraction 과정을 통해 급속 견인 후에 치수와 치주조직의 변화를 평가하였다. 유성견의 상악 제2소구치를 발거하고 제3소구치 근심의 치간골을 부분 제거하였다. 견인장치는 6일 동안 하루에 2번씩 견인하고, 강화기 동안 0주, 1주, 3주, 5주, 7주, 9주에 치수와 치주조직의 변화를 임상적, 방사선학적, 조직학적, 면역조직화화학적으로 관찰하였다. 신장된 치주인대 내에서 견인 직후부터 4주까지 활발한 골밀도 증가를 보였으며, 특히 2-3주 사이에서 가장 활발하였다. 강화기 0주에 압박측 치조골의 흡수 및 파골세포 출현, 염증세포 침윤이 가장 많이 관찰되었고 1주의 신장측 치주인대에서 특징적인 골형성을 보이기 시작하였다. 신생골 형성은 1주와 3주에 가장 많이 관찰되었으며 9주에는 성숙골로의 대치 및 치주인대의 재생으로 대조군과 차이가 없었다. 실험군의 calcitonin gene-related peptide의 발현은 치수, 치주인대 내의 염증 부위에서 나타났으며 0주, 1주에 압박측 치주인대에서 증가하였다가 5주 이후에는 감소하여 대조군과 차이가 없었다. 이상과 같은 소견은 periodontal distraction에 의한 급속 치아 이동이 정상적인 골 재형성 과정을 도모하는 새로운 치아이동 방법이 될 수 있음을 시사한다. Objective: The aim of this study was to evaluate pulp and periodontal changes following rapid tooth retraction by periodontal distraction after bone undermining surgery in young adult dogs. Methods: After extraction of second premolars, the interseptal bone mesial to the upper 3rd premolar was undermined. After activating the distraction appliance at 0.5 mm/day for six days, the dogs were sacrificed at 0, 1, 3, 5, 7, and 9 weeks during the consolidation period. Tissue changes of periodontium and pulp were evaluated radiologically, histologically, and immunohistochemically. Results: Digital subtraction radiography showed active bone formation in the stretched periodontal ligament from 0 - 4 weeks. Resorption of the alveolar bone, appearance of osteoclasts, and infiltration of inflammatory cells were observed just after the activation period at the pressure side, and distinctive bone formation was seen in the tension side of the periodontal ligament from 1 week. New bone formation was active at 1 - 3 weeks. The expression of calcitonin gene-related peptide in the experimental group was increased at the alveolar bone and pulp, and periodontal ligament at the pressure side from 0 - 1 week, and it decreased after 5 weeks to become similar to that of the control group. Conclusions: The results showed that rapid tooth movement using periodontal distraction can be new form of orthodontic tooth movement for accelerating normal bone formation.

한국인 상염색체 우성 다낭신 가계에서의 유전자 아형분석

이중건,안규리,황대연,황영환,어현선,채회진,이은주,조종태,김연수,한진석,김성권,이정상 대한신장학회 2000 대한신장학회잡지 Vol.19 No.4

RED 게이트웨이에서의 응답 메시지 처리 알고리즘

이상민,채현석,최명렬 漢陽大學校 工學技術硏究所 2001 工學技術論文集 Vol.10 No.-

본 논문에서는 RED 게이트웨이간의 전송률을 최대로 유지하며 종단에서 실제로 처리되어 전송되는 패킷의 양을 늘릴 수 있는 응답 메시지 처리 알고리즘을 제안한다. 본 논문에서 제안한 응답메시지 처리 알고리즘을 RED 게이트웨이에 적용하여 패킷의 손실을 줄이고 전송 효율을 높였으며, 모의 실험을 통해 성능의 향상을 확인하였다. 일련의 모의 실험에서는 응답메시지 처리 성능을 분석하고, 차후의 연구 방향을 제시한다. 본 논문은 네트워크 NS-2 시뮬레이터를 사용하여 다양한 TCP 버전의 조합과 RED 게이트간의 연결속도와 게이트의 개수에 변화를 주어 모의 실험 하였다. This paper proposes an act message processing algorithm to increase the throughput at the end of the telecommunication node, when it uses RED gateway to include various TCP versions with keeping the highest throughput between two RED gateways. This paper shows the results in Kbytes/s from a series of simulation experiments designed to analyze the performance of ark message processing algorithm. Using the ns-2 simulator, the simulation results have been conducted by changing the link speed between two RED gateways using the combination TCP Vegas and TCP NewReno.