만성 승모판 패쇄부전증 환자에서의 안지오텐신 전환효소 억제제의 장기 투여 효과

김대희,이명묵,이해영,조현재,박승정,서재빈,서정원,양한모,윤창환,조상호,이준희,김용진,김명아,손대원,오병희,박영배 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

만선신부전 환자에서 관상동맥조영술 소견에 관한 연구

한대희,김성구,박상호,김성한,조원영,방덕원,조윤행,정의룡,은영근,권영구 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

Background : Patients with chronic renal fialure have a substantially elevated risk of death from cardiovascular diseases than do the general population. the patients with chronic renal failure are at significantly increased freqeuncy of hypertension, hyperlipidemia, and diabetes mellitus which are known to the risk factors of the coronary artery diseases, and the prevalence of the coronary artery diseases in chronic renal failure patients is highly associated with the hemodynamic disorder and metabolic abnormalities. therefore we expected that the coronary angiographic findings in patients with chronic renal failure should be different from the general population (control groups) and investigated the risk factors contributing to coronary artery diseases. Method : we have retrospectively compared the coronary angiographic findings of 44 patients with chronic renal failure on hemodialysis with that of 88 patients in the general population and investigated the factors contributing to the development and acceleration of coronary artery diseases in patients with chronic renal failure Result : Hypertension and diabetes mellitus which is risk factors for coronary artery disease is significantly increased in patients with chronic renal failure, in coronary angiographic finding the severity of the lesion is worse. the incidence of PCI or CABG of patients with chronic renal failure is more than that of control group but statistically no difference between patients with chronic renal failure and control group. the sex, the duration of disease, the duration of dialysis, serum creatinine in patients with chronic renal failure have no correlation to the prevalence of coronary artery disease and severity of lesion. hyperglycemic patients with chronic renal failure have high incidence of coronary artery disease and are worse in the severity of lesion Conclusions : There is significantly increased the pevalence and severity of involving multiple coronary artery diseses in hyperglycemic patients with CRF.

사립유치원 원감의 애환과 보람 그리고 희망

정서영(Jung Seo-Young),이대균(Lee Dae-Kyun) 한국어린이미디어학회 2010 어린이미디어연구 Vol.9 No.1

본 연구는 사립유치원 원감들이 유치원에서 중간자적 위치의 삶을 살아가면서, 아픔으로 느끼는 다양한 애환과 다시 힘을 내게 하는 보람된 요소들, 그리고 미래에 대한 희망 등을 질적 연구방법을 통해 밝히고자 하였다. 2009년 9월부터 11월까지 총 11주 동안, 11명의 사립유치원 원감들을 연구 참여자로 하여 심층면담과 관련문서, 연구자의 반성적 저널쓰기를 통해 자료를 수집하였다. 수집한 자료를 분석한 결과 사립유치원 원감들은 애환의 요소로 원장과 교사와의 사이에서 매개체 역할, 모든 오류와 민원의 해결사 역할, 유아의 안전 문제로 인한 학부형 관계, 원감 자격 연수 과정 없이 업무를 시작함과 과도한 원아 모집 경쟁, 그리고 육아를 겸하는 데서 오는 어려움을 호소하였으며 보람의 요소로는 원장으로부터 인정 받음과 학부모의 격려 및 업무 수행에서 오는 성취감, 그리고 교사의 성장과 유치원의 발전을 보며 보람된 마음을 가질 수 있다고 하였다. 또한 앞으로 원장 연수를 받고 본인의 원을 경영하면서 자신의 교육철학이 반영된 좋은 프로그램을 마음껏 실천해 보기를 희망하고 있었다. The purpose of this research is to understand the position and life of the vice-principals who carry out their duties as a mediator and to clarify the meaning of it. The eleven participants for this research are selected out of the vice-principals serving in Gyung-gi and Cheon-an, Dae-jeon province considering various careers and characteristics. The duration of the research lasted for eleven weeks. To collect the data we used in-depth interview, phone interview, and e-mail interview with each participant and wrote a journal to record the flow and characteristics of the research. First of all, the private kindergarten vice-principals had so much difficulties in carrying out their duties. The first element can be the difficulties in playing a role as a mediator between the president who substantially runs the kindergarten and the teachers who educate the children near by. The second element of difficulties is the confusion caused by dealing with all the errors and public grievance whether anytime or anywhere. The third element is the safety issue of the children that can takes place any time and dealing with the parents with that issue. The forth element is to choose the vice-principals out of the president's authority unlike the public kindergartens that hire through systematical steps to be a vice-principals. The fifth element is the excessive competition in recruiting new students leads to overaction that ruins the principle and fundamental rule. The last element is the difficulty of maintaining both teaching and raising their own kids at the same time. Secondly, they felt worthwhile, having the motive power that enables the vice-principals's to move forward when they get the recognition from the president, which turned out as the best factor. Other factors also can be an encouragement from parents, a feeling of the satisfaction and achievement after an event. Besides, when the teachers are cooperative and new students keep signing up they find it worthwhile. Thirdly, the participants found the biggest hope in the systematically legitimate way of children educator that became most considerable meaning and they could get the feeling of the pride. After that, they talked about getting a training to be a president that can be the next goal for them to run their own kindergarten adapting good philosophy and programs.

세그먼트화 폴리우레탄을 이용한 고분자 마이크로 액츄에이터의 제작 및 고분자 전극의 상태에 따른 구동성능

정영대(Young Dae Jung),박한수(Han Soo Park),조남주(Nam Ju Jo),정해도(Hae Do Jeong) Korean Society for Precision Engineering 2005 한국정밀공학회지 Vol.22 No.2

This paper is focused on the development of the flexible electrode for disc-type polymer actuators using Segmented Polyurethane(SPU). This paper consists of two parts. The one is about the mechanical property such as elastic modulus. these parameters mainly affect behaviors of polymer actuators and the other is about the electro-chemical property such as the surface resistance of the composite electrode affects the strength of electrostatic force, results in the deformation of polymer actuators. The Young's modulus was measured by UTM. As result, by increasing the modulus of a body of polymer actuators, the maximum displacement of polymer actuators are decreased. The surface resistance of the electrode was measured by 4 point probe system. Compared with the conductive silver grease, the displacement of polymer actuators using carbon black(CB) composite electrodes is comparably small but CB composite electrode should be the practical approach for the improvement of the performance of all-solid actuators, compared with another types of electrode materials.

여성 연소노인의 지각연령에 따른 사회무용 지도자 선호에 대한 연구

정문미(Jung, Moon Mi),원영신(Won, Young Shin),고대선(Ko, Dae Sun) 한국노년학회 2010 한국노년학 Vol.30 No.2

본 연구는 여성 연소노인의 사회 인구학적 특성에 따른 지각연령의 차이를 알아보고 지각연령이 사회무용 지도자 선호에 미치는 영향을 규명하는 데 목적이 있다. 이와 같은 연구목적을 달성하기 위하여 서울지역 소재 노인교육기관(노인교실, 노인대학, 노인학교, 노인복지회관, 사회복지회관, 대학부설 평생교육원 및 사회교육원, 종교기관 등)에서 사회무용 프로그램에 참여한 경험이 있는 여성 연소노인을 모집단으로 설정한 다음, 유의표본표집법을 이용하여 450명의 연구대상을 표집하였으며, 불성실하게 응답한 자료를 제외하고 총 428명의 자료를 최종분석에 사용하였다. 자료처리는 SPSS Windows 15.0 version을 이용하여 빈도분석, 탐색적 요인분석, 신뢰도분석, 카이검정, 독립표본 t-test, 일원분산분석, 이항 로지스틱 회귀분석을 실시하였으며, 다음과 같은 결론을 도출하였다. 첫째, 사회 인구학적 특성에 따른 지각연령은 역연령, 교육수준에 있어서 지각연령 하위요인(보이는 연령, 느끼는 연령, 관심사 연령, 활동 연령) 모두에 유의한 차이가 나타났다. 또한 결혼유지 상태는 관심사 연령과 느끼는 연령, 경제수준은 보이는 연령, 관심사 연령, 느끼는 연령에 있어서만 유의한 차이가 나타났다. 둘째, 사회 인구학적 특성에 따른 사회무용 지도자 선호는 교육수준에 있어서 사회무용 지도자 선호 하위특성(성별, 연령, 교육수준, 전공경력) 모두에 유의한 차이가 나타났다. 또한 역연령은 지도자의 전공경력을 제외, 경제수준은 지도자의 성별을 제외한 모든 사회무용 지도자 선호 하위특성에 유의한 차이가 나타났으며, 결혼유지 상태는 지도자의 교육수준에 있어서만 유의한 차이가 나타났다. 셋째, 지각연령이 사회무용 지도자 선호에 미치는 영향을 분석한 결과, 지각연령의 하위 요소 중 보이는 연령만이, 사회무용 지도자 선호하위특성 중 전공경력을 제외한 성별(B=.458), 연령(B=.483), 교육수준(B=.76) 모두에 유의한 정적(+) 영향을 미치는 것으로 나타났다. The purpose of this study was to examine the demographic characteristics of the female young-old to their self-perceived age and the impact of their self-perceived age on preference for a social dance instructor. The subjects in this study were 450 women who were selected by purposive sampling from a population of the female young-old who had ever participated in social dance programs in senior education institutions senior class, senior college, senior shool, Senior welfare center, social welfare center, university, school of lifelong education, religion community) in Seoul. After a survey was conducted, the answer sheets from 428 respondents were analyzed except some incomplete ones. As for data handling, a SPSS Windows Ver. 15.0 program was employed, and a frequency analysis, exploratory factor analysis, reliability analysis, pearson chi-square, independent-samples t-test, one-way ANOVA and binary-logistic regression were utilized. The findings of the study were as follows: First, self-perceived age by social population characteristics shows significant difference in all lower factors of self-perceived age(Look age, Feel age, Interest age, Do age) as chronological age, education level. Also, the marriage status shows significant difference only in interest age and feel age, the economic level shows only in look age, interest age and feel age. Second, the social dance instructor preference by social population characteristics shows significant difference in the all lower facts of social dance coaches preference(gender, age, education level, instructor career) up to educational level. Also, chronological age without the instructor career, economic level without instructor gender show the significant difference in the lower facts of all social dance instructor preference. Also, marriage status shows the significant difference in the educational level of the instructor. Third, the analysis of the influence of self-perceived age on the instructor preference shows all gender(B=.458), age(B=.483) and educational lever(B=.76) without career were influenced in significant (+) way.

비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

한국인에서 혈소판 당단백 Ⅱb/Ⅲa 유전자 다형성과 관동맥 성형술 후 재 협착과의 관계

이민수,이정우,김보영,임대승,강정아,김정희,김윤철,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

Platelet aggregation is the final pathway of acute coronary syndrome such as acute myocardial infarction and unstable angina. Platelet glycoprotein IIb/IIIa is a membrane receptor for fibrinogen and yon Willebrand factor and it plays an important role in platelet aggregation and in the pathogenesis of acute coronary syndrome. It is known that polymorphism of the gene that encoding platelet glycoprotein IIb/IIIa(PI^A1/A2) is strongly related to acute coronary syndrome in Caucasian, but not in Koreans. We investigated relationship between platelet glycoprotein llb/Illa gene polymorphism and restenosis of coronary artery after angioplasty in Koreans. Total 371 patients(M=251. F=120) were enrolled. Angioplasty group comprised 143 patients who underwent coronary angioplasty, and in the angioplasty group, restenosis group comprised with the 65 patients who had restenotic lesion over 50% of luminal diameter in follow-up coronary angiography. Normal group comprised 153 patients who had no significant angiographic lesion and variant angina group comprised 75 patients who were positive in ergonovine test. Genomic DNA was extracted from peripheral arterial blood. To determine the frequency of P1^A1/A2 genotype, polymerase chain reaction(PCR) was done and the product was restricted with Mspl. 3%. agarrose gel electrophoresis showed restriction fragment length polymorphism. Clinical profile and risk factor were also reviewed. Among all 371 patients of study group, genotype of only one patients in restenosis group if is proven to be PI^A1/A2 heterozygote. All patients of normal study group, no restenosis group, and the other patients in restenosis group have an PI^A1 homozygote genotype. In our study, platelet glycoprotein IIb/Illa polymorphism has no relationship with restenosis of the coronary artery after angioplasty in Koreans. But the genotypic frequency of platelet glycoprotein IIb/IIIa gene polymorphism in Koreans is concordant with that of previous studies.

위암 환자의 복강내 투여를 위한 Activated Charcoal-Alginate Bead 제형으로부터 Mitomycin C의 용출 거동

이진호,최선웅,서중기,김동민,정경수,오정연,김진향,노승무,민병무,김용백,김창식,박근성,강대영,송규상,양준묵,조준식,정현용,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

Locoregional recurrence is the most common type of recurrence in surgical operation of gastric adenocarcinoma, and peritoneal dissemination is one of the most difficult problems in advanced gastric adenocarcinoma treatment. Because the peritoneal cavity is the most common site of the first recurrence after gastric cancer resection, intraperitoneal chemotherapy seems a logical choice for cancer chemotherapy. In this study, Mitomycin C (MMC)-activated charcoal (CH)-alginate (ALG) beads were prepared by the mixtures of CH particles adsorbed with MMC as an anti-cancer drug and aqueous alginate solution. The alginate is recognized as biodegradable, nontoxic, and biocompatible. The release of MMC from the beads in 0.1 M Tris buffer was stable and continuous until about 1 week. The MMC-CH-ALG beads can be applied in the peritoneal cavity for intraperitoneal chemotherapy since they provide a good adhesiveness on the tissue and controlled release pattern of the drugs.

선천성 기형을 동반한 단일 제대동맥 신생아 2례

정대봉,박동호,김명철,문경래,박영봉,박상기 朝鮮大學校 附設 醫學硏究所 1997 The Medical Journal of Chosun University Vol.22 No.1

A single umbilical artery is present in about 2/1,000 births. Approximately 10-15% of Infants with a single umbilical artery have congenital abnormalities, usually more than one, chromosomal abnormalities, fetal growth retradation, prematurity, perinatal mortality and many such infants are stillborn or die shortly after birth. We experienced two cases of single umbilical artery. One had congenital malformation of left ectopic fused kidney, but hadn't cytogenetic abnomality. The other had cytogenetic abnormality of 46XY,inv(6)(q11q16), morphologic abnormalities of polydactyly & lower palpebral fissure and congenital abnormalities of tracheoesophageal atresia & TOF. We reported these cases with a related literature review.

총체적 언어학습법이 읽기 학습장애아동의 독해력 및 읽기 태도에 미치는 효과

정대영,김지은 한국특수아동학회 2001 특수아동교육연구 Vol.3 No.-

본 연구는 총체적 언어 접근법이 읽기 학습장애 초등학생의 독해력과 읽기 태도에 미치는 효과를 탐색하였다. 연구대상자는 KEDI-WISC, 기초학습기능검사 및 KISE-학습장애 선별 척도의 검사 결과 본 연구에서 제시한 학습장애 아동을 진단하기 위한 조작적 기준을 만족하는 초등학생 3명이었다. 총체적 언어접근법을 이용한 읽기 지도 프로그램은 이들 대상자들에게 40-45분 단위의 40회기 동안 적용되었다. 본 연구는 초등학교 읽기 학습장애 아동에게 총체적 언어 학습 프로그램을 적용함으로써 독해력과 읽기 태도의 변화를 알아보기 위한 것으로 사전-사후-지연 설계를 사용했다. 아동들의 독해력에 미치는 영향을 알아보기 위해 읽기 학습장애아동들을 하나의 동질집단으로 보고 검사결과 획득한 정답을 평균으로 사전, 사후, 지연검사간 반복 측정식 변량분석을 하여 P≤.05 수준에서 효과를 검증하였다. 읽기학습장애 집단과(n=3)과 일반아동(n=32)을 각각 요약하기, 추론하기, 회상하기 등 각 독해력의 하위 영역에 따른 정답률을 사전, 사후, 지연검사간 반복 측정을 통한 변량분석을 실시한 후 P≤.05 수준에서 효과를 검증하였으며 개별 아동의 독해 방략 사용 능력에 미치는 효과를 알아보기 위해 각 영역별 변화 양상을 그래프로 제시하고 분석하였다. 읽기 학습장애아동의 읽기 태도로서 아동이 학습에 참여하는 모습을 듣기와 말하기 능력의 변화를 활동초기와 후기의 모습을 관찰 비교하여 알아보았다. 동화책을 이용한 총체적 언어접근법 중심의 독해 지도 프로그램은 읽기 학습장애 아동들의 독해력과 읽기 태도를 향상시키는데 긍정적인 효과를 보여주었다. 아울러, 본 연구는 읽기 학습장애 아동들의 지도 방법으로 더욱 발전ㆍ보완될 가치가 있음을 시사해 주고 있다. The purpose of the study was to examine the effects of the whole language approach on reading comprehension and reading attitudes of elementary students with reading disabilities. The subjects of the study were 3 students with reading disabilities who were selected as the results of the KEDI-WISC, the reading comprehension subtests of the Basic Academic Skill Test and the KISE-Learing Disabilities Rating Scales. The whole language approach program was consisted of 40 sessions of 40-45 mimutes. To evaluate the effects of the intervention, reading comprehension test was performed in pre and post training and maintanance phase. ANOVA(repeated test) was used to test the effects of this method on reading comprehension. The whole language approach with story books enhanced the literacy of the students with reading disabilities. When the activities are combined with speaking, listening, reading and activities, they caused some progress in the students' reading behaviors.