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      • 서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1994)

        김재홍,안진균,정성재,김영태,김중환,김시영,이석종,이홍렬,서호석,김경훈,권혁진,정우권,고우석,이용석,안필수,오준규,오용섭 대한화학요법학회 1996 대한화학요법학회지 Vol.14 No.1

        Background : In recent years gonorrhoea has been panendemic and remains one of the most common Sexually Transmitted Diseases in the world, especially in developing countries. Objective & Method : For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria Gonorrhoeae(PPNG), Ive have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results : In 1994, 168 strains of N. gonorrhoeae were isolated, among which 109 (64,9% ) were PPNG. Conclustion : Our results suggests that the prevalence of PPNG in Seoul is still increasing.

      • KCI등재
      • 위암 환자에서 세포성 면역 기능에 관한 연구

        이재익,윤일국,이종선,김종완,장준,안정기,송민호,정현용,이헌영,김삼용,김영건 충남대학교 암연구소 1991 癌共同硏究所 硏究誌 Vol.1 No.1

        We performed a variety of lymphocyte stimulation tests, delayed hypersensitivity skin tests, and enumeration of several lymphocyte subpopulations in 21 patients with gastric cancer who did not receive any form of anticancer therapy, and in 20 healthy controls. The gastric cancer patients had significantly decreased number and total score of positive reactions in delayed hypersensitivity skin tests compared with the healthy controls. The percent of CD_(4) positive lymphocytes in the gastric cancer patients was significantly decreased compared to the normal control subjects, but it had no correlation with the total score of delayed cutaneous hypersensitivity reactions. The ratio of helper to suppressor cells was lower in the cancer group. The uptake of 3H-thymidine was markedly depressed in cancer patients when stimulated with various mitogens. There was little correlation between any of the stimulation tests and any of the lymphocyte subpopulation proportions to delayed hypersensitivity cutaneous reactions. Optimal proliferative response was found in lymphocytes stimulated with 10 micrograms of concanavalin-A and 10 microgram of phytohemagglutinin. Advanced stage patients had greatly depressed delayed hypersensitivity skin reactions and proliferative responses to mitogens compared with localized diseases. These results suggest that gastric cancer patients have depressed cellular immune functions, which mainly result from the decreased helper cells and defects in functional proliferative response to mitogens. Interleukin-2 and interferon-gamma restored the in vitro proliferative response of lymphocyte in patients with gastric cancer.

      • 상업스포츠시설 이용자의 스포츠 소비행동에 관한 연구

        안영필,정종훈,조재기,김종백 東亞大學校 附設 스포츠科學硏究所 1995 스포츠科學硏究論文集 Vol.13 No.-

        With 509 regular members of commercial sports centers as the subjects, such variables as their consumption behavior, expectation & satisfaction were analyzed. For the purpose of setting up a strategic theory of marketing segmentation, this sports market's consumer characteristics and responses were segmented. The following sums up the conclusion : THE Segmentation Matrix of the Commercial Sports Center Market -------------------------------------------------------------------------------- Division Large Users (27.0%) Small Users (24.2%) -------------------------------------------------------------------------------- Class by skill(beginning, Expectation intermediate, advanced, sex, age) Parking lot. Shuttle buses Friendship matches with some invited athletes. ------------------------------------------------------------------------------- Satisfaction Convenient facilities and Price of using the center VIP or discount tickets. -------------------------------------------------------------------------------- Unsatisfactory in convenient Unsatisfactory in divers facilities, clean weter, programs,health counselling, periods and contens of leaders' advise and programs, technicques, class of by skill, number of price of using,shuttle buses, members a class,various and general environment. Satisfaction programs,health counselling, A little satisfactory in the Against leaders' advise,coaching items of parking lot and Expectation echnicques,price of using, special events for shuttle buses,parking lot, member's friendship and environment. Rather satisfactory in the items of convenient membership and attitude to customers. --------------------------------------------------------------------------------

      • 재생중인 흰쥐 간의 형태형성과 메탈로사이오닌 분포

        안영모,김완종 순천향대학교 기초과학연구소 2004 순천향자연과학연구 논문집 Vol.10 No.2

        Metallothionein(MT) is a low molecular weight (approximately 6,000~7,000Da), cysteine-rich protein (approximately 22~23%), metal-binding protein. MT is known to be induced by surgical operation and chemical agent, as carbon tetrachloride(CCI_(4)) and cadmium(Cd). The goal of the present study was to determine the distribution of the protein on regenerating rat liver after partial hepatectomy(PH). The results were as follow: Size of the remained liver increased at 1day after PH. Morphological changes were observed such as destroyed hepatocyte plate around central vein, enlarged nuclear cytoplasmic ratio and increased the number of hepatocytes with two nuclei. Expression of MT mRNA started to increase at 30 minutes, reached to maximum at 1 hour and maintained at 8 hours after PH. The level of MT mRNA showed similar to that of control group at 12 hours. On immunohistochemistry, in all groups treated with primary antibody, immunoreactivity indicating the presence of MT appeared moderately throughout both the cytoplasm and nucleus of rat hepatocyte. On the immunohistochemical analysis, immunoreactivities both in the cytoplasm and nucleus appeared after 4 hours, reached to maximum at 12 hours, and then it showed similar to those of normal control. These results suggested that the remained liver immediately entered cell proliferation and this MT protein during the process may be associated with transfer of factors needed to cell reproduction from the cytoplasm to the nucleus for regeneration of the liver after PH.

      • KCI등재후보

        경기도 오산천 주변의 잡초군락에 대한 식물사회학적 연구

        안영희,송종석 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

        Osancheon creek is located in the southwest of the middle area in Korea Weed community around the Osancheon creek, where various disturbances exert a bad influence directly on its community by human work or nature, was surveyed phytosocialogically. Our surveys have been accomplished from June, 2003 to September, 2003. Weed communities formed around the Osancheon creek were divided into several patterns and analysed. They have been divided into 8 communities. Community A: Humulus japonica community, B: Phragmites communiscommunity, C: Persicaria thunbergii community, D: L:ania latifolia community, E: Miscanthus sacchariljlorus community, F: Echinochica crusgalli community, G: Typha orientalis community, H: Sataria viridis community. The flora surveyed in these communities was constituted of 19 families, 36 genera, 4 varieties, and 40 species. Wild plants such as Artemisia princeps var. orientalis, Erigeron annuus, Bidens rrondosa, Aeschynomene indica and Oenothera odorata were mostly light loving plants and higher resistant plants against the disturbance. Our result from the ranking all surveyed areas by the Bray-Curtis ordination method was very similar to the results from phytosocialogical table work.

      • KCI등재후보

        Self-etching primer를 이용하여 접착된 교정용 브라켓의 전단결합강도

        안윤표,김효영,전영미,김정기 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.1

        본 연구는 6세대 교정용 접착 시스템인 Transbond Plus Self-Etching Primer(3M/Unitek Dental Products, Monrovia, Calif)를 이용하여 법랑질면에 브라켓을 접착하는 방법과, 통상적인 산부식 방법에 의해 브라켓을 접착한 경우의 전단결합강도 차이를 비교·평가하고, self etching primer를 이용하여 브라켓을 접착할 때 치면에 존재하는 수분이 브라켓의 전단결합강도에 미치는 영향에 관하여 조사하였다. 37% 인산용액과 Self-Etching Primer를 잉용하여 법랑질을 표면 처리하고 Transbond XT를 이용하여 브라켓을 치면에 부착하였다. 또한 수분의 존재에 따른 전단결합강도의 차이를 평가하기 위해 인공타액을 치면에 도포후 Self-Etching Primer를 사용하여 브라켓을 부착한 후 30분과 24시간에 따른 전단결합강도를 비교 평가하여 다음과 같은 결론을 얻었다. 1. Self-etching primer군에서 건조군과 습윤군의 전단결합강도는 37%인산처리군의 결합강도보다 낮았다(p<0.05). 그러나 Self-etching primer군의 전단결합강도는 임상적으로 유용한 수준의 이상이었다. 2. 모든군에서 24시간군의 전단결합강도가 30분군의 전단결합강도보다 높았으며(p<0.05), 이는 브라켓 접착후 일정시간의 경과가 결합강도를 증가시켜 줌을 알 수 있었다. 3. Self-etching primer군에서 습윤군의 전단결합강도는 건조군보다 높은 경향이었으나 통계적 유의성은 인정되지 않았다(p<0.05). 4. ARI 점수의 비교결과 인산처리군에서는 0점과 1점의 빈도가 높았으며, Self-etching primer 건조군과 습윤군에서는 2점과 3점의 빈도가 높아(p<0.05) Self-etching primer군이 인산처리군보다 법랑질-레진 접착계면부위에서의 파절이 많이 일어남을 알 수 있었다. The purpose of this study was to evcaluate the effects of a self-etching primer on the shear bond strength of orthodontic brackets and on the failure pattern of bracket-adhesive interfaces in dry or wet condition. Brackets were bonded to extracted human teeth according to one of three experimental protocols. In the Group P, teeth were etched with 37% phosphoric acid. After the Transbond XT Primer was applied onto the etched surfaces, the brackets were bonded with Transbond XT(3M, Unitek, Monrovia, Calif) and light cured for 40 seconds. In the Group SD, a self-etching primer(3M, Unitek, Monrovia, Calif) was placed on the enamel for 3 seconds and gently evaporated with air, as suggested by the manufacturer. The brackets were then bonded with Transbond XT as in the Group P. In the Group SW, artificial saliva was applied to the enamel surface for 10 seconds to allow complete hydration of the surface before application self-etching primer. The brackets were then bonded following the procedures of Group SD. Each group was divided into 2 sub-groups(0.5h, 24h) according to debonding time shear bond strengths were measured by Instron universal testing machine. After debonding, the teeth and brackets were examined under scanning electron microscope and assessed with the adhesive remnant index. The result obtained were summarized as follows ; 1. The shear bond strengths were high enough to use clinically in all testing groups, but the shear bond strengths of group SD and SW were significantly lower than Group P(p<0.05). 2. With respect to comparison of debonding time, 24h debonding samples exhibited heigher shear bond strength than 0.5h debonding samples in Group P, SD and SW(p<0.05). 3. In the self etching primer groups(Group SD and Group SW), there was no significant difference in mean shear bond stredifference in mean shear bond strength between under dry and wet state(p>0.05). 4. There was a greater frequency of ARI score of 0 and 1 with the Group P. On the other hand, there was a higher frequency of ARI scores of 2 and 3 with Group SD and Group SW(p<0.05).,

      • 블럭펄스 변환에 의한 비선형계의 준최적제어에 관한 연구

        안두수,이명규,김종부,고영기 成均館大學校 科學技術硏究所 1990 論文集 Vol.41 No.1

        This paper presents a method of suboptimal control for nonlinear systems via block pulse transformation. The adaptive optimal control scheme proposed by J.P. Matuszewski is introduced to minimize the performance index. Nonlinear systems are controlled using the obtained optimal control via block pulse transformation. The proposed method is simple and computationally advantageous. Viablity of the this method is established with simulation results for the van der Pole equation for comparision with other methods.

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