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      • 자기 효능의 개념 분석

        서순림,이은남,박송자,양영희,이동숙,최은옥,구미옥,김인자,이인숙,김성재,박영임,이은옥 서울대학교 간호대학 간호과학연구소 1997 간호학 논문집 Vol.11 No.1

        Today human needs for health promotion and maintenance are increasing. The nursing progression has a great responsibility for helping clients to practice good health behavior. self efficacy was found to be potent predictor in initiating and maintaining the health-related behavior. Therefore, the concept is important in nursig intervention for change of health behavior. The purpose of this paper was to analyze and clarify the meaning of the concept, self efficacy. This study used Walder & Avant's process of concept analysis. Critical attributes of self efficacy were : 1) positive perception of his won capability; 2) intrapersonal strength; 3) possibility of being learned; 4) individuality; 5) specificity; 6) generalizability. Antecedents of self efficacy consist of those facts that 1) new situation occurs; 2) individuals have needs to change the new situation; 3) there are some required actions in new situation. Consequences occurring as a result of self efficacy consist of those facts that 1) individual initiates the of failure; 5) cope with the situation; 6) controls the situation; 7) the level of self efficacy is enhanced; 8) the level of self-esteem is enhanced.

      • KCI등재

        아동의 내적 동기 및 자기효능감과 창의성의 관계 : 성별과 연령을 중심으로

        김은아,정옥분,정순화 이화여자대학교 교육과학연구소 2007 교육과학연구 Vol.38 No.2

        The purpose of this study was to investigate the relationships betweenintrinsic motivation, self-efficacy, and creativity of children. The subjects of thisstudy consisted of 304 fourth, fifth, and sixth grade public elementary schoolstudents in Seoul, Korea. The data were analyzed by using frequencies,percentiles, means, standard deviations, Cronbach’s a, two-way ANOVAs,Pearson’s correlations, and a multiple regression analysis. The major findings of this study were as follows: (1) There were significantdifferences in intrinsic motivation, self-efficacy, and creativity in terms ofgender and grade. Girls had higher scores in intrinsic motivation, self-efficacy,and creativity. Also, intrinsic motivation, self-efficacy, and creativity scoresincreased with grade. (2) Intrinsic motivation and creativity, self-efficacy andcreativity are significantly correlated each other. (3) Gender, intrinsic motivation(task difficulty preference), and grade were the variables that significantlypredict creativity. These variables explained 12.3% of children’s creativity. 본 연구의 목적은 아동의 내적 동기 및 자기효능감과 창의성의 관계를 살펴보는 데 있다. 연구대상은 초등학교 4~6학년 아동 304명이며, 자료에 대한 분석은 빈도와 백분율, 이원분산분석, 상관분석, 다중회귀분석방법을 사용하였다. 연구결과 내적 동기, 자기효능감 그리고 창의성은 성별과 학년에 따라 유의한 차이가 있는 것으로 나타났다. 내적 동기, 자기효능감, 창의성 총점에서 남아보다는 여아의 점수가 더 높은 것으로 나타났다. 또한 내적 동기, 자기효능감 그리고 창의성은 학년에 따라 증가하는 것으로 나타났다. 아동의 내적 동기, 자기효능감,창의성 간에는 밀접한 관련이 있는 것으로 나타났으며, 특히, 아동의 내적 동기와 창의성은 유의한 상관이 있는 것으로 나타났다. 아동의 창의성을 예측하는 변인은 ‘성별’과 내적 동기의 하위 영역 중 하나인 ‘도전적 과제선호’ 그리고 ‘학년’으로, 이 세 변인들의 설명력은 12.3%로 나타났다.

      • 下體部의 動作에 따른 Slacks의 製作時 여유분량에 관한 硏究

        金恩姬,咸玉相 啓明大學校生活科學硏究所 1992 科學論集 Vol.18 No.-

        To establish a marginal part of slacks in accordance with motion and habitus, I hereby classified the married woman in their thirties by three habitus : thin, standard, and fat. Then affer selecting a standard classified by each habitus I studied the variation of body surface and the cross-cut method. I accordingly conducted a functional test by making a standard clothes of which the reasonable marginal parts-1cm, 1.5cm, 2cm, 2.5cm-had been established. The results of the test are as follows; 1. Concerning the variation of body surface, the variation rate increased when the habitus became bigger, and the width of variation did when the radius of the articutation movement became larger. The widthe of increase classified by parts showed a considerable increase in Hip Girth, Thigh Girth, and Midle Waist Girth-the horizontal items-of habitus A, B, C. In the vertical items, Back Line, Front Line and Center Back Line showed a considerable increase. But Later Line showed a constraction in all movements. When marking proper slacks, the establishment of marginal part of Hip Girth in accordance with the habitus should be considered. 2. Concerning the analysis of space variation of cross-cut, the space variation increased when the movement became larger and the habitus became bigger. 3. As a result of the comparison between the variation of body surface and the space variation in Cross-cut method, the variation was remarkable when the movement became larger, and the length of slacks became longer. But when putting on clothes, the Cross-cut method having a restriction on articulation movement showed a considerable variation in measures. In consideration of the a fore-mentioned results, when making clothes, the establishment of marginal part, which took the fact that there is an interrelation between movement and wearing clothes because the restriction on articulation causes the decrease in a radius of movement when wearing clothes into serious consideration, is necessary. 4. The result of functional test; Habitus A : The test clothes having marginal part of 1㎝ was rated good, getting 4.74marks in appearance test, 4.36marks in functional test. Habitus B : The test clothes having marginal part of 1.5cm was also rated good, getting 4.88marks in appearance test, 4.42marks in functional test. Habitus C : The test clothes having marginal part of 2cm was rated best, getting 4.70marks in appearance test. The test clothes having marginal part of 2.5cm got 4.30marks in functional test. In conclusion the establishment of marginal part of 0.5 to 1㎝ universally applicable in making a standard slacks causes the married women in their thirties to feel inconvenience on the parts of Center Front Line, Hip and Belly in functional and beautiful in silhouette as possible, the appropriate establishment of marginal parts assified by each habitus in essential.

      • Alkylhalide가 Mouse의 LDH isozyme 분포에 미치는 영향 : Cellulose Acetate Electrophoresis Method

        권미경,김영옥,박은주,이동화,이명미,이문희,이양자 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

        The effect of Carbontetrachloride administration on Lactatedehydrogenase isozyme patterns were analyzed by cellulose acetate electrophoresis for the brain, heart, kidney, lung, liver and mouse muscle. Each other tissue was found to have a characteristic distribution of these isozymes. At normal condition, aerobic tissue such as brain, heart, kidney, and lung were found to have all five isozymes from LDH_1 to LDH_5, while anaerobic tissues such as liver and muscle were found to have superiorly LDH_5 The toxicity of Carbontetrachloride administration was most prominence in the liver, and lung toxicity was occured also.

      • 결핵성 흉막염 환자의 진단에 있어서 ICT Tuberculosis^(�) 검사를 이용한 유용성 연구

        박희선,조은경,송창화,정성수,김주옥,김선영 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

        The incidence of tuberculous pleuritis is high in Korea where the disease is endemic. Diagnosis of tuberculous pleuritis is often problematic for its difficulty in detecting microorganism by stain or culture and sometimes it is not available and to obtain specimens from the pleura because highly invasive procedures are needed. Repeated pleural biopsy is almost always hard for patients. Recent studies on tuberculosis have interest on new methods for accurate and rapid diagnosis. Serologic assay is one of the new imerging diagnostic method for tuerculosis and extrapulmonary tuberculosis. Total 38 subjects admitted in the Department of Respiratory Division of Internal Medicine of Chung-Nam National University Hospital are involved in this study. Median age of patients with tuberculous pleuritis was 40 years old, ranging from 18 to 88 years. All patients were receving treatmented by combination anti-tuberculous therapy after the test. The cardboard folding device contained a nitrocellulose strip on which the 38-kDa antigen from M. tuberculosis has been applied. When a specimen (pleural effusion, serum) flows past the nitrocellulose strip, antibodies specific for the 38-kDa antigen bind to the antigen line. In a reverse flow, the bound antibodies are detected by a goat anti-human immunoglobulin G antibody conjugated to colloidal gold particles and show a pink to red positive line. The test is completed in a maximum of 15 minites. Two of the 38 subjects showed positivity. One case was from the pleura and the other from the serum. From the above data, we concluded that ICT Tuberculosis^( ) test is not effective in the diagnosis of tuberculous pleuritis.

      • 복강경 검사로 진단한 결핵성 복막염 1례

        박민경,서원석,박재옥,김창휘,고은석,임철완 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Tuberculous peritonitis is discovered from sixty to ninty percent of pulmonary tuberculosis patients. Clinical symptoms are nonspecific such as mild fever, weakness and malaise but show tenderness in right lower abdomen and abdominal distension. Diagnosis is confirmed by laparoscopic and pathologic findings. We report a case of tuberculous peritonitis in an 11-year-old boy who was hospitalized because of abdominal distension with pain on right lower abdomen which had developed one day before he came to hospital. Chest X-ray showed pleural effusion on both sides. We did laparoscopic examination and observed diffuse nodular infiltration. In biopsy specimen we observed osseous granuloma and acid-fast bacilli in AFB stain.

      • 생활의 질적 향상을 위한 부엌의 작업대 및 수납장에 관한 연구

        김여은,김은주,김재희,김현애,김희경,성은희,옥여명,이선희,전연희,조성진 연세대학교 생활과학대학 1985 婦學 Vol.18 No.-

        The purpose of this study was to examine present conditions of kitchen work centers and cabinets and to determine responses of residents in relation to them. The sample comprised of 42 households in Seoul. A questionnaire was developed, which consisted of three parts; socio­demographic information of the households, present conditions of kitchen work centers and cabinets, and their responses in relation to them. Data was analyzed by hand, using frequency and percentage. Findings from this study were as follows: 1. L shape and one wall kitchen shape were dominated, 55.0% and 32.0% respectively. The kitchen work centers were arranged most frequently in sequence of refrigerator center, sink center, mixing center, cooking center, and serving center. 2. Widths/heights of kitchen work centers and cabinets were close to the recommended measurements, however the vertical distance between the top line of kitchen work centers and the bottom line of wall cabinets showed higher than the recommended measurement. 3. Residents were satisfied to some degree with the sequence of arrangement, heights, widths, design, and color of kitchen work centers and cabinets, however they need more storage space. 4. The functional aspect and design were the major factors influenced residents' decision making for the buying behavior of the kitchen work centers and cabinets.

      • KCI등재후보

        Genetic heterogeneity of liver cancer stem cells

        Minjeong Kim(Minjeong Kim),Kwang-Woo Jo(Kwang-Woo Jo),Hyojin Kim(Hyojin Kim),Myoung-Eun Han(Myoung-Eun Han),Sae-Ock Oh(Sae-Ock Oh) 대한해부학회 2023 Anatomy & Cell Biology Vol.56 No.1

        Cancer cell heterogeneity is a serious problem in the control of tumor progression because it can cause chemoresistance and metastasis. Heterogeneity can be generated by various mechanisms, including genetic evolution of cancer cells, cancer stem cells (CSCs), and niche heterogeneity. Because the genetic heterogeneity of CSCs has been poorly characterized, the genetic mutation status of CSCs was examined using Exome-Seq and RNA-Seq data of liver cancer. Here we show that different surface markers for liver cancer stem cells (LCSCs) showed a unique propensity for genetic mutations. Cluster of differentiation 133 (CD133)-positive cells showed frequent mutations in the IRF2, BAP1, and ERBB3 genes. However, leucine-rich repeat-containing G protein-coupled receptor 5-positive cells showed frequent mutations in the CTNNB1, RELN, and ROBO1 genes. In addition, some genetic mutations were frequently observed irrespective of the surface markers for LCSCs. BAP1 mutations was frequently observed in CD133-, CD24-, CD13-, CD90-, epithelial cell adhesion molecule-, or keratin 19-positive LCSCs. ASXL2, ERBB3, IRF2, TLX3, CPS1, and NFATC2 mutations were observed in more than three types of LCSCs, suggesting that common mechanisms for the development of these LCSCs. The present study provides genetic heterogeneity depending on the surface markers for LCSCs. The genetic heterogeneity of LCSCs should be considered in the development of LCSC-targeting therapeutics.

      • The role of hedgehog signaling during gastric regeneration.

        Kang, Dae-Hwan,Han, Myoung-Eun,Song, Moo-Ho,Lee, Young-Suk,Kim, Eun-Hee,Kim, Hyun-Jung,Kim, Gwang-Ha,Kim, Dong-Heon,Yoon, Sik,Baek, Sun-Yong,Kim, Bong-Seon,Kim, Jae-Bong,Oh, Sae-Ock Springer International 2009 Journal of gastroenterology Vol.44 No.5

        <P>Hedgehog signaling plays critical roles during embryonic development. It is also involved in tissue regeneration and carcinogenesis in various adult tissues. Moreover, it regulates the maintenance of cancer stem cells and adult stem cells. Although hedgehog signaling is important in gastric carcinogenesis, its role in gastric regeneration has not been previously examined. In the present study, we evaluated the expression and roles of hedgehog signaling during gastric regeneration.</P>

      • KCI등재

        Antioxidant Capacity and Anti-inflammatory Effect of the Ethyl Acetate Fraction of Dried Persimmon (Diospyros kaki Thumb.) on THP-1 Human Acute Monocytic Leukemia Cell Line

        Eun Ock Kim,이형재,Chi Heung Cho,김영준,김대옥 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.4

        Antioxidant capacity and anti-inflammatory effect of ethyl acetate (EtOAc) fraction of phenolic extract from dried persimmon (Diospyros kaki Thumb.) were investigated on THP-1 human acute monocytic leukemia cells. Phenolic extract of dried persimmon was sequentially fractionized using five different solvents, hexane, chloroform, EtOAc, butanol, and water, among which EtOAc fraction showed the highest antioxidant capacity. Cytotoxicity of THP-1 cells pretreated with the EtOAc fraction and curcumin was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Curcumin and the EtOAc fraction showed respective cytotoxicities at 30 and 100 μg/mL. Expression level of proinflammatory tumor necrosis factor-α (TNF-α) was quantified by enzyme-linked immunosorbent assay. TNF-α production was significantly inhibited by curcumin and the EtOAc fraction at 20 and 50 μg/mL, respectively. These results showed that phenolic compounds of dried persimmon alleviated the augmentation of TNF-α level induced by lipopolysaccharide in THP-1 cells, suggesting that dietary uptake of dried persimmon may be beneficial to promote anti-inflammation.

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