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      • 750kW급 풍력발전기의 부하 모니터링 시스템에 관한 연구

        남윤수,장후영,윤태준 江原大學校 産業技術硏究所 2008 産業技術硏究 Vol.28 No.A

        The exact load measurements for the mechanical parts of wind turbine are important step both for evaluation of specific wind turbine design and for a certification process. A wind turbine monitoring system is essential equipment for mechanical load analysis of a wind turbine. This monitoring system is based on IEC 61400-13 and strain gage are used to measure a mechanical load of wind turbine. Also this system monitors signals from a meteorological mast. The measured signals which are sampled at 200 Hz are automatically saved on a data file in the unit of ten minutes. A detail explanation for the developed wind turbine monitoring system is presented in this study.

      • 압저항형 스마트 실리콘 압력 센서의 설계

        정후민,신윤권,조상복,이종화 울산대학교 2001 공학연구논문집 Vol.32 No.2

        압저항형 스마트 실리콘 압력 센서를 0.6 ㎛ 이중 폴리 실리콘 이중 금속 CMOS 공정으로 구현하기 위하여 설계하였다. 이 스마트 실리콘 압력 센서는 압저항형 저항기들로 된 휘스톤 브리지를 갖는 다이아프램과 op-amp, A/D 변환기, 및 UART 회로 등의 주변회로 들로 구성되어 있다. 브리지 회로의 출력 전압과 압력에 의한 기계적 응력 사이의 관계를 COSMOS-M 상용프로그램으로 다이아프램의 응력 분포를 모의실험하여, 압저항기의 최적의 위치와 크기에 대한 연구를 하였다. CMOS op-amp 회로는 규정된 출력 특성을 얻기 위하여 크기가 다른 트랜지스터들로 설계하여 HSPICE로 모의실험하여 최적화 시켰다. A/D 변화기 회로는 가능한 칩 면적을 줄이기 위하여 서브 레인징 기법과 신경 MOSFET 구조를 이용하여 설계하였다. UART회로는 VHDL 소스 코드와 셀 라이브러리를 이용하고 Synopsys로 합성하여 설계하였다. 회로의 물리적 레이아우트 설계는 Mentor 틀로 설계하였다. 그러나 온도보상회로와 출력오프셋 문제는 아직 해결하지 못하고 다음에 연구할 예정이다. A piezoresistive smart silicon pressure sensor is designed to implement with 0.6 ㎛ double-polysilicon double-metal CMOS precess. This smart pressure sensor is composed of a diaphragm with piezoresistive resistors' Wheatstone bridge and the peripheral circuitry of op-amp, A/D converter and UART. The relationship between the output voltage of the bridge circuit and the mechanical stress by applied pressure was studied by simulating the stress distribution on the diaphragm with COSMOS-M package program to optimize the size and position of piezoresistors. The CMOS op-amp circuit was designed with different CMOS transistor sizes to obtain the defined op-amp output characteristics and simulated with HSPICE. The A/D converter was designed using neuron MOSFET structure and sub-ranging method to minimize the chip area. The UART circuit was designed by using VHDL source code and cell library and by synthesizing with Synopses and the physical layout of the circuit was designed with Mentor tools. The problems for temperature compensation and the output voltage offset were not yet considered.

      • 대장에 발생한 샘암종에서 MUC1과 MUC2 점소 발현의 의의

        이윤경,이주호,이용,심재영,박정훈,오수섭,박진실,기근홍 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

        Background : Mucins possess the unique function of protecting and lubricating the epithelial surface and other important functions such as call growth, direct implication in the fetal development, the epithelial renewal and differentiation, the epithelial integrity, carcinogenesis, immune regulation, cellular adhesion and metastasis. Purpose : This study was done to provide the significance of alteration of MUC1 and MUC2 expression in colorectal adenocarcinoma, A series of 131 colorectal adenocarcinomas including 11 mucinous carcinomas were screened immunohistochemically for their expression of MUCI and MUC2, Materials and mehtods : Of 131 carcinomas, 76 (58,5%) were MUCI positive and 91 (68, 9%) were MUC2 positive, In normal colonic goblet cells, MUCl was not expressed but MUC2 was expressed in cytoplasm, Conclusion There were up-regulation of MUCI and down-regulation of MUC2 in colorectal carcinomas, The frequency of MUC2 positivity according to differentiation was statistically reliable. (p=0.0001)

      • 자동입력시스템을 위한 도면미화에 관한연구

        郭義鍾,尹厚炳,鄭成鍾 全北大學校 1994 論文集 Vol.37 No.-

        As the diverse of industry increase information to handle, requirement of automatic input system has been increased. And these automatic input systems have been developed as the font of various kinds of recognition system. Expecially. drawing recognition system which is an automatic input system of drawing has been studied since 1970. But most of those systems are on-line system. On-line system can not continously display a status of making drawing by restriction of size of monitor, And can not input a printed data or hand drawn data with keyboard. In this paper, an off-line system to beautify the input data coming through scanner is proposed, and input data is a hand drawn data or printed data consisting of texts and graphics. To do this process, input data will be separated into line component, loop component, text. As shown in results, hand drawns or printed datas are separated into charater, line, and loop component. And also these separated component are beautified through symbol recognition.

      • KCI등재
      • A study on convergence and complexity of reproducing kernel collocation method

        Hu, Hsin-Yun,Lai, Chiu-Kai,Chen, Jiun-Shyan Techno-Press 2009 Interaction and multiscale mechanics Vol.2 No.3

        In this work, we discuss a reproducing kernel collocation method (RKCM) for solving $2^{nd}$ order PDE based on strong formulation, where the reproducing kernel shape functions with compact support are used as approximation functions. The method based on strong form collocation avoids the domain integration, and leads to well-conditioned discrete system of equations. We investigate the convergence and the computational complexity for this proposed method. An important result obtained from the analysis is that the degree of basis in the reproducing kernel approximation has to be greater than one for the method to converge. Some numerical experiments are provided to validate the error analysis. The complexity of RKCM is also analyzed, and the complexity comparison with the weak formulation using reproducing kernel approximation is presented.

      • KCI등재

        MiR-1224-5p modulates osteogenesis by coordinating osteoblast/osteoclast differentiation via the Rap1 signaling target ADCY2

        Hu Liangcong,Xie Xudong,Xue Hang,Wang Tiantian,Panayi Adriana C.,Lin Ze,Xiong Yuan,Cao Faqi,Yan Chengcheng,Chen Lang,Cheng Peng,Zha Kangkang,Sun Yun,Liu Guodong,Yu Chenyan,Hu Yiqiang,Tao Ranyang,Zhou 생화학분자생물학회 2022 Experimental and molecular medicine Vol.54 No.-

        MicroRNAs (miRNAs) broadly regulate normal biological functions of bone and the progression of fracture healing and osteoporosis. Recently, it has been reported that miR-1224-5p in fracture plasma is a potential therapy for osteogenesis. To investigate the roles of miR-1224-5p and the Rap1 signaling pathway in fracture healing and osteoporosis development and progression, we used BMMs, BMSCs, and skull osteoblast precursor cells for in vitro osteogenesis and osteoclastogenesis studies. Osteoblastogenesis and osteoclastogenesis were detected by ALP, ARS, and TRAP staining and bone slice resorption pit assays. The miR-1224-5p target gene was assessed by siRNA-mediated target gene knockdown and luciferase reporter assays. To explore the Rap1 pathway, we performed high-throughput sequencing, western blotting, RT-PCR, chromatin immunoprecipitation assays and immunohistochemical staining. In vivo, bone healing was judged by the cortical femoral defect, cranial bone defect and femoral fracture models. Progression of osteoporosis was evaluated by an ovariectomy model and an aged osteoporosis model. We discovered that the expression of miR-1224-5p was positively correlated with fracture healing progression. Moreover, in vitro, overexpression of miR-1224-5p slowed Rankl-induced osteoclast differentiation and promoted osteoblast differentiation via the Rap1-signaling pathway by targeting ADCY2. In addition, in vivo overexpression of miR-1224-5p significantly promoted fracture healing and ameliorated the progression of osteoporosis caused by estrogen deficiency or aging. Furthermore, knockdown of miRNA-1224-5p inhibited bone regeneration in mice and accelerated the progression of osteoporosis in elderly mice. Taken together, these results identify miR-1224-5p as a key bone osteogenic regulator, which may be a potential therapeutic target for osteoporosis and fracture nonunion.

      • SCOPUSKCI등재
      • 한국과 중국간의 고로슬래그 미분말 및 플라이 애시의 품질 규정 비교

        후윈야오 ( Hu Yun-yao ),임군수 ( Lim Gun-su ),김종 ( Kim Jong ),한민철 ( Han Min-cheol ),한천구 ( Han Cheon-goo ) 한국건축시공학회 2022 한국건축시공학회 학술발표대회 논문집 Vol.22 No.2

        In this study, the quality of mineral admixture, Comparison of blast-furnace slag(BS) and fly ash(FA)in Korea and China. In the case of BS, Korea is mainly classified into 1 type to 4 types according to the specific surface area, whereas China is classified into S105, 95, and 75 according to the activity index of 28 days of age. In the case of FA, Korea is like BS, is mainly classified into types 1 to 4 according to specific surface area, whereas China is classified into F, C (class F, class C) by ingredients and class I, II, and III according to powder and ignition loss.

      • KCI등재

        MRI Features of Spinal Epidural Angiolipomas

        Su Hu,Chun-hong Hu,Xiao-yun Hu,Xi-ming Wang,Hui Dai,Xiang-ming Fang,Lei Cui 대한영상의학회 2013 Korean Journal of Radiology Vol.14 No.5

        Objective: To describe the MRI findings in ten patients of spinal epidural angiolipoma for differentiated diagnosis presurgery. Materials and Methods: Ten surgically proved cases of spinal epidural angiolipomas were retrospectively reviewed, and the lesion was classified according to the MR findings. Results: Ten tumors were located in the superior (n = 4), middle (n = 2), or inferior (n = 4) thoracic level. The mass, with the spindle shape, was located in the posterior epidural space and extended parallel to the long axis of the spine. All lesions contained a fat and vascular element. The vascular content, correlating with the presence of hypointense regions on T1-weighted imaging (T1WI) and hyperintense signals on T2-weighted imaging, had marked enhancement. However, there were no flow void signs on MR images. All tumors were divided into two types based on the MR features. In type 1 (n = 3), the mass was predominantly composed of lipomatous tissue (> 50%) and contained only a few small angiomatous regions, which had a trabeculated or mottled appear. In type 2 (n = 7), the mass, however, was predominantly composed of vascular components (> 50%), which presented as large foci in the center of the mass. Conclusion: Most spinal epidural angiolipomas exhibit hyperintensity on T1WI while the hypointense region on the noncontrast T1WI indicates to be vascular, which manifests an obvious enhancement with gadolinium administration.

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