남자 알코올 의존 환자의 기질적 특성에 관한 연구

김성곤,민영기,이덕기,김미영,송영상,권도훈,고영훈,박제민,정병선 대한생물치료정신의학회 2003 생물치료정신의학 Vol.9 No.1

목 적: 본 연구의 목적은 한국인 남자 알코올 의존 환자의 기질적 특성을 Temperament and Character Inventory(TCI)를 이용하여 조사하는 것이다. 방 법: DSM-Ⅳ 진단 기준에 맞는 알코올 의존 환자 30명과 정상인 36명을 대상으로 연구학적 특성을 조사하고, 기질적 특성을 한글판 TCI를 이용하여 조사하였다. 모든 대상자의 나이는 30~60세였다. 결 과: 1) 두 군간 평균 나이는 유의한 차이가 없었으나, 교육 정도와 결혼을 유지하고 있는 비율 및 취업률은 알코올 의존군이 정상 대조군에 비해 유의하게 낮았다. 2) 알코올 의존군에서는 정상 대조군에 비해 Harm Avoidance(HA) 점수와 Self-transcendence(ST)점수는 유의하게 높았으며, Self-directiveness(SD)점수는 유의하게 낮았다. 3) 알코올 의존군 내에서의 각 척도들 간의 상관관계는, HA와 SD 점수, HA와 Persistence(PE) 점수, ST와 SD 점수는 각각 유의한 음의 상관관계, ST와 PE 점수, SD 점수와 Cooperativeness(CO) 점수, Reward Dependence(RD)와 CO 점수는 양의 상관관계를 보였다. 결 론: 이러한 본 연구의 결과는 한국인 남성에서 수줍음을 잘 타며, 걱정도 많고, 염세적이고 쉽게 피로해지는 기질적 특성이 알코올 의존과 연관성이 있음을 의미한다. Objectives : The purpose of this study was to assess the temperament of male parients with alcohol dependence. Methods : The subjects were 30 patients who met DSM-Ⅳ criteria for alcohol dependence and 36 normal controls. All subjects completed Temperament and Character Inventory(TCI) which was developed by Cloninger. Results : 1) The educational level, marital status, and occupation in alcohol dependence group were significantly lower than those of normal control group, but there was no difference in the age between two groups. 2) Among the scores of TCI, the score of harm avoidance(HA) and self-transcendence(ST) were significantly higher in the alcohol dependence group than in the normal control group. 3) In the alcohol dependence group, a significant negative correlation among the scores of TCI was between HA and SD, HA and Persistence(PE), ST and SD, and positive correlation between ST and PE, SD and Cooperativeness(CO), Reward Dependence(RD) and CO. Conclusion : These results suggest that shy, fearful, pessimistic and fatigable temperament are related to developing alcohol dependence in Korean males.

자가 산부식 프라이머의 적용시간이 상아질의 미세인장 결합강도에 미치는 영향

조영곤,이영곤,김종욱,박병철,김종진,최희영,진철희,유상훈 大韓齒科保存學會 2004 Restorative Dentistry & Endodontics Vol.29 No.5

This study evaluated the influence of application time of self-etching primers on microtensile bond strength (μTBS) to dentin using three self-etching primer adhesive systems. Dentin surfaces were exposed from forty-eight human molars. They were conditioned with three self-etching primers (Clearfil SE Bond [SE], Unifil Bond [UF], Tyrian SPE + One Step Plus [TY]) and different primining times (10s, 20s, 30s and 40s). Composite resins were bonded to dentin surfaces and specimens were made. μTBS was tested and statistically compared using by one-way ANOVA and Tukey's Test. The results of this study presented that priming time for 10s in SE and UF groups and for 30s and 40s in TY group was highly decreased μTBS to dentin.

상아질에 대한 자가 산부식 접착제의 전단결합강도와 SEM 분석 비교

조영곤,노기선,김수미,이영곤,정진호,기영재 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.3

The purpose of this study was to compare shear bond strength and interfacial pattern of composite bonded to dentin using self-etching adhesive systems. Sixty extracted human molars with exposed occlusal dentin were divided into four groups and bonded with four adhesives and composites: Single Bond/Filtek Z 250(SB), Tyrian SPE-One-Step Plus/Aelitefil(TY), Prompt L-Lpop/Filtek Z 250(LP), and one-Up Bond F/Palfique Toughwell(OU). The results of this study were as follows; 1. Shear bond strength for OU was significantly lowet than that of other groups(p<0.05). No significant difference was founded among SB, TY, and LP. 2. Failure modes to dentin showed adhesive and mixed for SB, TY, and LP, but them for OUT showed adhesive in all spceimens. 3. Dentin-resin interface showed close adaptation for SB, TY, and LP, but it showed gap for OU. 4. The hybrid layers for TY, LP, OU were thinner than that of SB. Adhesive layers were observed between composite and hybrid layer, which were 5 ㎛ thick for TY and 10 ㎛ thick for OU.

치질에 접착된 자가 산부식 프라이머와 자가 산부식 접착제의 형태학적 양상

조영곤,이석종,정진호,이영곤,김수미 大韓齒科保存學會 2003 Restorative Dentistry & Endodontics Vol.28 No.1

The purpose of this study was to compare in vitro interfacial relationship bonded with three self-etching primer adhesives and one self-etching adhesive. Class I cavity preparations were prepared on twenty extracted human molars. Prepared teeth were divided into four groups and restored with four adhesives and composites: Clearfil SE Bond/Clearfil^™ AP-X (SE), UniFil Bond/UniFil® F (UF), FL Bond/Filtek^™ Z 250 (FL) and Prompt L-Pop/Filtek^™ Z 250 (LP) After storing in distilled water of room temperature for 24 hours, the specimens were vertically sectioned and decalcfied, Morphological pattern between the enamel/dentin and adhesives were observed under SEM. The results of this study were as follows; 1. They showed close adaptation between enamel and SE, UF and FL except for LP. 2. The hybrid layer in dentin was 2 ㎛ thick in SE, 1.5 ㎛ thick in UF, and 0.4 ㎛ in both FL and LP. So, the hybrid layers of SE and UF were slightly thicker than that of FL and LP. 3. The lengths and diameters of resin tages in UF and FL were similar, but those of LP were slightly shorter and slenderer than those of SE. 4. The resin tags were long rod shape in SE, and funnel shape in other groups. Within the limitations of this study, it was concluded that self-etching primer adhesives showed close adaptation on enamel. In addition, the thickness of hybrid layer ranged from 0.4-1.5 ㎛ between adhesives and dentin. The resin tags were long rod or funnel shape, and dimension of them was similar or different among adhesives.

다용량 비타민 C 투여가 생쥐 세포매개면역반응에 미치는 영향

노가화,김헌곤,신영아,임현자,문성규,이용택,이왕재,이동섭,황영일 Official Journal of the Korean society for immunol 2003 Immune Network Vol.3 No.3

Bleomycin이 모낭의 기질세포에 미치는 영향에 관한 전자현미경적 연구

이영만,김잉곤,류재만 한양대학교 의과대학 1993 한양의대 학술지 Vol.13 No.2

Bleomycin, one of antibiotic drug, produced by a strain of Streptomyces verticillus is used effectively in the treatment of various cancer. It is well known that bleomycin acts on the cancer cell by binding to nuclear DNA, causing single-strand scission and in turn inhibition DNA synthesis. Although bleomycin is very beneficial to cancer patient, it may damage ot normal cells. The author has undertaken this study to pursue the morphological changes of hair folliclis caused by bleomycin injection. Healthy male mice of DDY strain weighing about 20 gm were used in this experiment. Animals of the experimental group were intraperitoneally administrated with 15mg/kg bleomycin diluted in 0.2ml distilled water for injection by bid for 7days. The experimental animals were sacrificed at 1,3days, and 1,2 weeks after administration of bleomycin and specimens, skin of abdomen, were rejected. Some specimens were fixed 10% formalin for 24 hours and stained with hematoxylin and eosin. The others were prefixed in 2% glutaraldehyde-2.5% paraformaldehyde solution at 4℃ during 2-4 hours and postfixed in 1% osmium tetroxide solution. Ultrathin sections were made and double stained with urany1 acetate and lead citrate. These preparations were observed with light microscope and electron microscope (Hitachi H-600), respectively. The results were as follows: 1.The number and length of the hair folliclis were decreased and number of matrix cells were also reduced in skin in 1 day, 3 day and 1 week groups after administration of bleomycin. In 2 week group, hair follicles were similar to those of the normal control group. 2.Swollen mitochondria, mitochondria with indistinct double membranes and mitochondrial cristae, and degenerated mitochondria with horse-shoe shape were recognized cristae, and degenerated mitochondria with horse-shoe shape were recognized in 1 day, 3 day and 1 weed groups after bleomycin administration. In 2week group, swollen mitocondria and mitochondria with disorganized mitochondrial cristae and double membranes were observed. 3.The amounts of free ribosomes were markedly reduced in 1 day group after administration of bleomycin and slightly decreased in 3 day and 1 week groups. In 2 week group, distribution of free fibosomes were similar to that of the normal control gorup. 4.The cisternae of the rough endoplasmic reticulum with detachment of membrane-bound ribosomes were slihtly dilated in 1 day, 3 day groups after administration of bleomycin. In 2 week group, rough endoplasmic reticulum were similar to that of the normal control group. 5.A number of autophagic vacuoles were observed in 1 day, 3 day groups after administration of bleomycin and whorled membranous body was seen in 1 week group. Consequently, it is suggested that bleomycin would induce degenerative changes on the matrix cells of the hair follicle in mouse skin, but these damage are recovered as time goes by.

상아질 삭제기구가 자가부식 접착제의 결합강도에 미치는 효과

이영곤,문소라,조영곤 大韓齒科保存學會 2010 Restorative Dentistry & Endodontics Vol.35 No.1

이 연구는 다이몬드 포인트와 카바이드 버 및 SiC paper로 삭제한 상아질에 대한 자가부식 프라이머 접착제의 결합강도를 비교하고, 실험실에서 사용하는 SiC paper와 유사한 결합강도를 나타내는 회전용 삭제기구를 알아보기 위하여 시행하였다. 56개의 발거된 대구치 치관의 교합면 상아질을 노출시켜 1.2 mm의 두께의 시편을 제작한 후 8개의 군으로 분류하였다. 1군은 standard diamond point (TF-12), 2군은 fine diamond point (TF-12F). 3군은 extrafine diamond point (TF-12EF), 4군은 cross-cut carbide bur (no. 557), 5군은 plain-cut carbide bur (no. 245), 6군은 P 120-grade SiC paper, 7군은 P 220-grade SiC paper, 8군은 P 800-grade SiC paper를 사용하여 각 시편의 상아질 표면을 약 0.2 mm정도 삭제하였다. 상아질 표면에 Clearfil SE Primer와 Bond를 적용하고 Tygon tube를 이용하여 Clearfil AP-X를 충전하고 40초간 광조사 하였다. 제작된 시편은 만능시험기를 이용하여 를 미세전단 결합강도는 측정한 후, 각 군의 결합강도를 one-way ANOVA와 Tukey검정을 이용하여 분석하여 다음과 같은 결과를 얻었다. 자가부식 프라이머 접착제 사용 시 상아질에 대한 개선된 접착을 위해서는 초미세입자 다이아몬드 포인트의 사용이 추천되며, 실험실적인 연구에서 P 220-grade SiC paper의 사용은 미세입자 다이아몬드 포인트나 카바이드 버로 삭제한 상아질 면과 유사한 결합강도를 나타내었다. The purpose of this study was to compare the microshear bond strength of a self-etching primer adhesive to dentin prepared with different diamond points, carbide burs and SiC papers, and also to determine which SiC paper yield similar strength to that of dentinal surface prepared with points or burs. Fifty-six human molar were sectioned to expose the occlusal dentinal surfaces of crowns and slabs of 1.2 mm thick were made. Dentinal surfaces were removed with three diamond points, two carbide burs, and three SiC papers. They were divided into one of eight equal groups (n = 7); Group 1: standard diamond point(TF-12), Group 2: fine diamond point (TF-12F), Group 3: extrafine diamond point (TF-12EF), Group 4: plain-cut carbide bur (no. 245), Group 5: cross-cut carbide bur (no. 557), Group 6 : P 120-grade SiC paper, Group 7: P 220-grade SiC paper, Group 8: P 800-grade SiC paper. Clearfil SE Bond was applied on dentinal surface and Clearfil AP-X was placed on dentinal surface using Tygon tubes. After the bonded specimens were subjected to uSBS testing, the mean uSBS (n = 20 for each group) was statistically compared using one-way ANOV A and Tukey HSD test. In conclusion, the use of extrafine diamond point is recommended for improved bonding of Clearfil SE Bond to dentin. Also the use of P 220-grade SiC paper in vitro will be yield the results closer to dentinal surface prepared with fine diamond point or carbide burs in vivo.

益胃升陽湯 및 加減方이 家兎의 摘出腸管 運動에 미치는 影響

李學宰,盧永範,柳道坤,韓宗鉉,康舜洙 圓光大學校 韓醫學硏究所 1992 원광한의학 Vol.2 No.1

In order to investigate the action of Radix Bupleuri and Radix Cimicifugae in Yikwiserugyangtang(益胃升陽湯), Yikwiseungyangtang was divided into six samples : Sample Ⅰ : Yikwiseungyangtang Sample Ⅱ : Water extract of Yikwiseungyangtang excluded R.Bupleuri and R.Cimicifugae. Sample Ⅲ : Water extract of Yikwiseungyangtang excluded R.Cimicifugae. Sample Ⅳ : Water extract of Yikwiseungyangtang excluded R.Bupleuri. Sample Ⅴ : Water extract of Yikwiseungyangtang increased R.Bupleuri and R.Cimicifugae to 3.75g Sample Ⅵ : Water extract of R.Bupleuri and R.Cimicifuage. Effects of Yikwiseungyangtang and its variants on the contractile force of isolated rabbit ileums are as follows : 1. Yikwiseungyangtang was significantly increased the contractile force of isolated rabbits ileum. 2. The contractile of Yikwiseungyangtang was significantly inhibited by atropine. 3. The contractile force of Yikwiseungyangtang was not inhibited by cyproheptadine. 4. In the contraction of Norepinephrine(10^-3M), Sample Ⅱ, Sample Ⅵ and Sample Ⅴ were increased the contractile force than that of Sample Ⅰ. 5. In the contraction of acetylcholine (10^-3M), no change observed in contractile force than that of Sample Ⅰ.

POSIX 쓰레드를 이용한 SR 실행 환경 지원에 관한 연구

이명준,박양수,정영필,김영곤 울산대학교 1995 공학연구논문집 Vol.26 No.1

병행성은 컴퓨터 시스템에서 주요한 추상화중의 하나이다. 이러한 병행성은 하드웨어의 디자인과 오퍼레이션, 운영체제, 다중프로세서, 분산계산, 실시간시스템, 프로그래밍 언어와 시스템의 디자인 수단으로 사용되어왔다. 운영체제 서비스에 대하여 응용 프로그램들의 원시코드 이식성을 제공하기 위하여 최근 몇년동안 운영체제에 대한 응용 프로그램 인터페이스를 위한 일련의 표준화 작업으로 IEEE의 운영 체제 기술 협의회는 POSIX를 개발해오고 있다. POSIX 쓰레드 확장에 관한 표준안은 운영체제 서비스가 하나의 프로세스내에서 제어의 다중 쓰레드를 생성하고 수행하는 것을 지원하는 응용 프로그램 인터페이스를 지원한다. 우리는 이러한 POSIX 쓰레드를 사용하여 SR 언어의 실행지원 시스템을 새로이 설계 및 구현한다. 개발된 실행지원 시스템의 이식성은 POIX 쓰레드를 지원하는 시스템들 사이에서 자연스럽게 보장된다. 주어진 컴퓨터 시스템에 대하여 이 새로운 실행지원 시스템의 성능은 그 시스템에서의 POSIX 쓰레드 자체의 구현에 대한 질에 좌우된다. 특히 그 시스템이 많은 프로세서를 가지고 이러한 프로세스들을 효과적으로 지원하도록 POSIX 쓰레드가 구현되었을때 이 새로운 실행지원 시스템은 매우 유용하게 된다. Concurrency is one of the key abstractions in Computer System. It has relevance to hardware design and operation, operating systems, multiprocessor and distributed computation, real-time systems, programming languages and system design methods. To provide source code portability of operating system services for application programs, POSIX is being developed for the recent several years by the IEEE Technical Committee on Operating System as a family of standards for application program interface to an operating system. The draft standard POSIX Threads Extension provides an application program interface to operating system services supporting the creation and execution of multiple threads of control within a single process. Using this POSIX Threads, we present a new design and implementation of the runtime support system of SR. Naturally, the portability of the runtime support system developed is guaranteed between the systems supporting POSIX Threads. For a given system, the performance of the new runtime support system depends on the quality of the implementation of POSIX Threads for the system. In particular, when the system has a lot of processors and the implementation of POSIX Threads utilizes those processors effectively, the new runtime support system is very useful.

재생골재 콘크리트 강도의 조기추정에 관한 실험적 연구 : 마이크로파 가열기법을 중심으로 Focusing on Microwave Method

이민경,박희곤,양동일,김우재,이영도,정상진 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

In many countries a considerable amount of demolition wastes is generated and wastes concrete constitutes a significant proportion of the construction waste. Therefore, the necessity for the use of recycled aggregate in concrete arise and the reuse of a waste concrete may solve the problems of environmental pollution and shortage of natural aggregate. According to this study is to examine the possibility of site adoption microwave-use early strength estimation method. Based on the existed study related the plain concrete, the interrelation between recycled aggregate concrete and microwave-use early strength estimation method is required.