활성탄상의 heptafluoropropane 합성에서 반응온도의 효과

김재덕,이윤우,임종성,이경환,이윤용 社團法人 韓國火災 ·消防學會 1998 한국화재소방학회논문지 Vol.12 No.1

Thioacetamide에 의한 BALB/c 마우스 간의 시간별 약물대사효소 억제 양상 : A Time-Course Study

이정운,고우석,김갑호,배연경,하현정,한상섭,천영진,정태천 영남대학교 약품개발연구소 2001 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-

Thioacetamide is a potent hepatotoxicant which requires metabolic activation by cytochrome P450s (P450s) for toxicity. In the present study, the elevation kinetic of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities by thioacetamide treatment was investigated in male BALB/c mice. Inaddition, the inhibitory effects of thioacetamide on liver microsomal P450 enzymes were further investigated. Thioacetamide at 100 mg/kg/ was treated intraperitoneally for 6, 12, 24, 36, 48 and 72 hr. The blood was collected at the designated time for assaying the serum enzyme activities. To determine the P450 isozyme-specific activities. ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD), and benzyloxyresorufin O-debenzylase (BROD) activities were determined for P450 1A1, 1A2 and 2B1, respectively, in liver microsomal fractions. The activities of ALT and AST were started to be elevated 6 hr after thioacetamide treatment andreached the maximun at 36 hr after the treatment. The elevated activities were dramatically recovered at 72 hr. The microscopic exmination of the liver specimen also showed a similar profile of hepatotoxicity. All P450-associated enzyme activities were time-dependently inhibited by the treatiment with thioacetamide. The maximum inhibition of P450 enzymes was observed 36 hr after the treatment. Because the inhibition of P450 enzymes by thioacetamide was time-dependent, our present results suggest that thioacetamide might inhibit P450 enzymes in mechanism-based inactivation.

태양의 고도에 대한 6학년 학생의 개념인식 유형 조사

이연우,우종옥 한국교원대학교 과학교육연구소 1994 청람과학교육연구논총 Vol.4 No.1

본 연구는 ‘태양의 고도’에 대하여 국민학교 6학년 학생들이 가지고 있는 개념인식유형을 조사한 것이다. 이 연구에서는 서울소재 국민학교 6학년 학생 211명을 무선 군표집하였으며, 지필검사와 면담을 병행하여 조사하였다. 이 연구에 의하면 1) 학생들은 태양의 고도에 대하여 다양한 개념인식유형을 가지고 있으며, 2) 특히, 태양광선이 ‘대류’를 한다든가, 혹은 ‘흘러내린다’라는 식으로 “유체”와 동등한 성질을 가진 것으로 인식하고 있었으며, 3) 또, 태양광선은 지표에만 닿아서 오로지 지표만을 가열시킨다고 생각하였다. The purpose of this study is to analysis the patterns of concepts of sixth-grade-students on "altitude of the sun". For this study, 211 students were sampled from sixth-grade-students in Seoul, and studied by both paper-tests and interviews. Now, we could get the conclusions as the following. 1) The selected students had the various patterns of concepts on altitude of the sun. 2) Especially, the students conceived 'lights of the sun' as "fluid". 3) Or, the students conceived that lights of the sun contact with the ground directly.

구내 표준 방사선사진을 이용한 구내방사선촬영기의 선질 평가

이상섭,권혁락,심우현,오승현,이지연,전국진,김기덕,박창서 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : This study was to evaluate the beam quality of intraoral X-ray equipments used at Yonsei University Dental Hospital (YUDH) using the half value layer (HVL) and the characteristic curve of intraoral standard X-ray film. Materials and Methods : The study was done using the intraoral X-ray equipments used at each clinical department at YUDH. Aluminum filter was used to determine the HVL. Intraoral standard film was used to get the characteristic curve of each intraoral X-ray equipment. Results : Most of the HVLs of intraoral X-ray equipments were higher than the least recommended thickness, but the REX 601 model used at the operative dentistry department and the X-707 model used at the pediatric dentistry department had HVLs lower than the recommended thickness. The slopes of the characteristic curves of films taken using the PANPAS 601 model and REX 601 model at operative dentistry department, the X-705 model of prosthodontic dentistry department, and the REX601 model at the student clinic were relatively low. Conclusion : HVL and the characteristic curve of X-ray film can be used to evaluate the beam quality of intraoral X-ray equipment. In order to get the best X-ray films with the least radiation exposure to patients and best diagnostic information in clinical dentistry, X-ray equipment should be managed in the planned and organized fashion. (Korean J Oral Maxillofac Radiol 2000; 30: 183-188)

유구치 치근분지부 병소의 치수절제술과 소파술에 의한 골재생

이승현,우연선,김재문,정태성,김신 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

유구치의 깊은 우식은 치수병소을 유발하고 이를 조기에 치료하지 않을 경우에는 치수강저의 수많은 부근관을 통하여 치근분지부 병소로 이어진다. 지금까지 대부분의 교과서나 문헌에서는 이와 같은 경우를 발치의 적응증으로 기술하여 왔고 임상에서도 상례적으로 발치를 흔히 시행하였다. 그러나 유구치의 조기 상실은 수많은 부작용을 낳는 것이 필연적이다. 어린이의 골재생 능력이 우수하며, 치수강저와 치근분지부를 잇는 많은 부근관이 있음을 생각해 볼 때 유구치 치수 내의 감염원을 치수절제술로 제거하고, 이미 발생한 치근분지부 병소에 대해서는 소파술을 시행한다면 치근분지부 골조직의 신속한 재생이 가능하지 않을까하는 의문이 제기되었다. 본 중례는 3~6세 어린이에서 유구치 치근분지부 방사선 투과상이 2~4mm 정도의 깊이를 보이는 비교적 경미한 수준이면서, 연조직 누공을 보이는 10개 중례를 선별하여 치수절제술과 치근분지부 소파술을 시행한 결과, 모두에서 방사선적으로 골재생이 관찰되었다. 이를 통하여 유구치 치근분지부 병소나 누공을 보이는 모든 경우가 발치의 적응증은 아니며, 이 방법이 치근분지부 병소를 가진 유구치를 잔존시킬 수 있는 하나의 대안이 될 수 있음을 알 수 있었다. 그러나 이 방법이 객관적인 타당성을 얻기 위해서는, 병소의 크기와 진행정도, 계승 영구치의 성숙도, 환아의 연령 등 적응증에 대한 보다 심층적인 검토와 연구가 필요할 것으로 사료되었다. Deep caries in primary molars without early intervention frequently induce a pulpal disease and consequent furcation lesion with fistulous openings. Up to now, majority of the textbooks on pediatric dentistry and literatures have described that extraction of the inflicted teeth is indicated for these cases and in reality these teeth have usually been extracted in the dental clinics. However, when we recognize the excellent capacity of bone regeneration in children and the presence of numerous accessory canals at furcation areas, the removal of infection source in pulp by pulpectomy and inflammatory granulation tissues at furcation areas by furcal curettage might open the possibility of rapid healing at the furcation region. In this report. 10 cases of primary molars in 3 to 6-year-old children with fistulous openings and furcation lesions in moderate size of 2 to 4mm in depth radiolucency at furcation lesion have been chosen. After pulpectomy and furcal curettage, evident bone regeneration was detected rediographically in all cases. Through the cases, we came to realize that all the cases previously described are not the indications of extraction and this approach could make many cases with pulp and furca combined lesions survive and remain healthy in the children's dental arches. However, in order for this approach to acquire objective appropriateness. it is thought that more scrupulous evaluation is desirable on the various factors regarding the indication such as the extent of furcation, absorption status of teeth, amount of covering bone on succeeding teeth and so on.

발전기 고정자 권선용 마이카/에폭시 수지의 표면 및 구조분석

이상교,심재선,정의남,송우창,박하용,심상흥,임윤희,박종국,심낙순 三陟大學校 1998 論文集 Vol.31 No.1

The purpose of this study is to determine the ageing mechanism of Mica/Epoxy composite material for large generator stator windings in order to estimate remaining life of generator. X-ray analysis is performed to investigate the position and structure of mica crystal in insulation materials. The phase change of aged and sound specimen under each atmosphere isn't observed. Surface analysis of insulation materials by optical microscope also show that the sound and aged specimen, sliding phenomenon by shear and thermal stress is observed both interface between mica and epoxy.

남성·여성의 혼합DNA에서 Y-STR의 유효성 검토

이양한,신상철,이은정,박정우,구형남,김대열,김윤신 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

블록2D FFT를 이용한 지문 특이점 추출

이연우,김혜경,남시병 삼척대학교 산업과학기술연구소 2001 産業科學技術硏究論文集 Vol.6 No.1

In this paper, we propose a minutiae extraction algorithm using the block 2D FFT from the binarization fingerprint images. At first, binary fingerprint images carry out the histogram equalization and block binarization processing. For extract fingerprint minutiae, we executed the 2D FFT to block that divided into the 32×32 blocks from binarization image. Next step is removing the pseudo minutiae from the block for the minutiae extraction. Removing Pseudo minutiae processes executed the removing horizontal, vertical direction elements and diagonal lines. So that it extracts the core and delta points remained which include the blocks. In the end, we extract the minutiae by removing the block part of the delta point. Also, we gained efficient throughput 88% extraction rate of minutiae to the number of 50 fingerprint image.

사회과 교수행동의 기초와 기본에 근거한 학습모형

이양우,임윤섭 晋州敎育大學校 初等敎育硏究所 1993 初等敎育硏究 Vol.3 No.-

알코올 의존 환자의 MMPI 특성 : 임상 척도와 내용 척도를 중심으로

이윤경,오상우,류미경,박민철 圓光大學校 醫科大學 神經精神科學敎室 1999 圓光精神醫學 Vol.15 No.2

본 연구는 군집 분석을 이용하여 알코올 의존 환자의 MMPI 임상척도와 내용 척도의 특성을 알아보았다. 연구 결과, 60명의 남자 알코올 의존 환자들은 2개의 하위 유형으로 분류되었다. 첫 번째 집단은 모든 척도가 T 점수 45 ~ 55 범위에 있는 정상 유형이었고(n=40, 66.6%), 두번째 집단은 MMPI 타당도 척도의 L, F, K 가 역전된 V형이며 임상 척도는 6-8 유형을 보였다(n=20, 33.4%). 내용 척도에서도 두 집단간에 통계적으로 유의미한 차이가 있었는데, 첫 번째 집단은 프로파일이 정상범위에 속했으며, 두 번째 집단은 ANX, FRS, OBS, HEA, BIZ, ANG, HYP, LSE, SOD, TRT 척도의 T 점수가 첫 번째 하위 유형에 비해 의미있게 상승하였다. 본 연구는 MMPI 임상 척도와 내용 척도가 알코올 의존 환자의 임상적인 진단과 연구에 도움이 된다는 것을 시사한다. This study was to investigate the characteristics of MMPI clinical and content scales on patients with alcohol dependence by using cluster analysis. As a result, the 60 male patients with alcohol dependence were classified into two subtypes. The MMPI profile of first subtype was within normal range, 45~55 of T score(n=40, 66.6%), second subtype had the inverted V shape validity scales and 6-8 clinical scale profile(n=20, 33.4%). The content scale was statistically significant difference between two groups. First subtype was within normal range, second subtype had more elevated T score of ANX, FRS, OBS, HEA, BIZ, ANG, HYP, LSE, SOD, and TRT scale. This study suggest that the MMPI clinical and content scale can be helpful and applicable to clinical diagnosis and research in patients with alcohol dependence.