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      • Characterization of cricket song patterns and the behavior observation of Teleogryllus emma (Orthoptera:Grylloidea)

        Ji Chang Woo,Kim Nam-Jung,Lee Sang-Guei,Hwang-Yong Kim,Choi Hoon-Sik,Song In-Sun,Ko Jee Sun 한국응용곤충학회 2010 한국응용곤충학회 학술대회논문집 Vol.2010 No.05

        We analyzed the chirp sound and behavior of Teleogryllus emma with observation system, which was consisted of computer, ccd-camera and microphone. Computational methods of wavelet transformation and Self-Organizing Maps (SOM) were utilized to characterized the chirp sound of insect species for automatic counting in this study. Wavelets were initially applied to feature extraction of the chirp sound. Wavelet coefficients were accordingly calculated based on the basis function (e.g., Morlet). The obtained coefficients were subsequently provided to count number of chirps in each song. Sound structure of insect specimens consisted with long chirp and short chirp and the patterns of song were grouped by frequency of long chirp and short chirp. The song patterns of insect specimens were divided by Self-Organizing Map (SOM) that was used number of chirp as input data. Application of computational methods to automatic detection of chirp sound was further discussed for obtaining objective assessment in behavior science.

      • 대전지방 도시단독주택 지붕ㆍ현관ㆍ창호의 형태에 관한 조사연구

        宋容浩,金尙謙,趙原德 忠南大學校 産業技術硏究所 1986 산업기술연구논문집 Vol.1 No.2

        Roof, porch and window are important exterior elements which constitute the building envelope. This is a research on these elements of urban detached houses in Taejon area to suggest the basic data for housing design. The research is executed by enquete survey, photographs, sketch, measurement of size and survey sheets. By analyzing the elements according to the building ages, type, size, materials and color, and then comparing them with the traditional elements, the findings extracted the following criteria; 1) the inclination of roof type/color. 2) the tendency of establishing porch. 3) the changing aspects of window type/materials/color as well as those of entrance door.

      • 대전 기존도심의 보행자 공간 기본 구상

        宋容浩,李相이 忠南大學校 地域開發硏究所 1998 地域開發論叢 Vol.10 No.-

        This research aims to propose the pedestrian space at old downtown in order to activate the existing CBD in Taejon. The first part reviews the urban problems happened in modern metropolitan and meaning of pedestrian space as an effective & economic method renovating urban environment. The second part reviews the traffics & activities, the traffic control system, and the renovation scheme of the pedestrian space. The conclusions are as follows; 1) To be successful pedestrian space bases on the control of traffics and the resolution of district traffic at the old downtown. 2) The old downtown area needs to be made as a pedestrian zone so that urban activities will be strengthen with new added functions 3) The concept of pedestrian zone based on human life must be adopted to the whole city in the future.

      • SCOPUSKCI등재

        붕어입 모양 절개를 이용한 미세혈관문합술

        송상용,하범준,박영진 大韓成形外科學會 1998 Archives of Plastic Surgery Vol.25 No.7

        There are various methods of anastomosing or attaching the two ends of a severed blood vessel together. The most popular method is suturing, but it is tedious and time-consuming, has a tendency to leak between suture sites, and requires special training in microvascular surgery. Other anastomosis methods such as mechanical devices, tissue adhesives, lasers and modified suturing also have problems in achieving easy, reliable and fast anastomosis, and high patency rate. We developed a new eversion method to eliminate some of the current problems by allowing a quicker, simpler, and more reliable method of attachment. Our method consists of fish-mouth incision to the severed ends of vessels parallel to the vascular direction simultaneously accompanied by 2 stitches to the top of the incised vessels to obtain complete eversion and intima-to-intima contact. In this study, four clinical methods of attachments were compared; group 1, conventional interrupted suture, group 2, fish-mouth incision method with fibrin glue, group 3, fish-mouth incision with continuous horizontal mattress suture, group 4, fisy-mouth incision with angulated vascular ligating clips. We compare the patency rate and time required for anastomosis. histological changes(postoperative 1 week, 3 weeks) were also investigated to illustrate the endothelial regeneration, hyaline degeneration, microthrombus, and microaneurysm of anastomosis site. All the groups has similar high patency rate(p > 0.05). But, there was significant difference in anastomosing time among conventional suture method(group 1; average 45 minutes) and other methods(group 2; average 24 minutes, group 4; average 18 minutes). Especially, using fish-mouth incision with ligating clips, we could shorten the anastomosing time extremely. Microscopically, we found the relatively smooth healing surface of the anastomosis site with less hyaline degeneration, microthrombus, and microaneurysm in the groups using fish-mouth incision with fibrin glue and with ligating clip compared to conventional suture group. With fish-mouth incision method, possible advantages include consistent eversion of intima producing a continuous intimal surface within the lumen, tight sealing of the vascular edges, and minimal leakage. Moreover, operative time by using fibrin glue and ligating clip was significantly shorter and the patency rates were similar to the conventional suture method.

      • 여성생식계 상피세포에서 Glutathione S-Transferase 출현도에 관한 면역조직화학적 관찰

        송계용,김석중,김미경,박용욱,유재형,박상철 중앙대학교 의과대학 의과학연구소 1991 中央醫大誌 Vol.16 No.2

        Both placental form (GST-Pi) and basic form (GST-L) of glutathione S-transferase were studied in the epithelium of normal, tumor and tumor like lesions of female genital system. The results obtained were as follows : 1. Staining reaction of GST-Pi were moderate in normal cytotrophoblasts, mild in syncytiotrophoblasts, strong in corpus luteum, moderate to strong in salpingeal mucosa and in proliferative glands, moderate in secretory glands of indometrium and moderate in superficial squamous epithelium of cervix 2. Staining reaction of GST-L were mild in cytotrophoblasts and in syncytiotrophoblasts, of chorionic villi in corpus luteum, negative in salpingeal mucosa, very weak in proliferative glands, mild in secretory, glands of endometrium and in superficial squamous epithelium of cervix. 3. Staining reaction of GST-L were mild in cytotrophoblast and syncytiotrophoblast of choriocarcinoma, moderate in cytotrophoblasts, mild in syncytiotrophoblasts of hydatidiform mole, negative in mucinous epithelium of cust adenoma, in hyperplastia and adenocarcinoma, and mild in adenocarcinoma of cervix. 4. Staining reaction of GST-L were very weak in cytotrophoblasts and syncytiotrophoblasts of choriocarcinoma and in hydatidiform mole, negative in mucinous epithelium of cust adenoma, very weak in serous eptiethlium, negative to mild in hyperplastic and adenocarcinoma, mild in squamous cell carcinoma and adenocarcinoma of cervix. Therefore, staining reaction and distribution of GST-Pi and L isoengumes were different in normal and neoplastic cell of trophoblasts, salpinx, endometrin and cervix

      • KCI등재후보

        말기 신부전 환자에서 투여 경로에 따른 유전자 재조합 인 Erythropoietin(Epokine^(�))의 효과와 안정성에 대한 연구 : 제 4상 연구 A Phase 4 Single Center Study

        송현용,윤향숙,강신욱,최규헌,하성규,이호영,한대석 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.2

        목 적 : 국내 독자적 기술로 첫 개발된 유전자 재조합 인 에리트로포에틴(Epokineⓡ)의 투여방법에 따른 유효성과 안정성을 알아보고자 하였다. 방 법 : Epokineⓡ을 주당 100-150 U/kg, 주 2회, 12주간 피하 주사하여 목표 또는 안정된 혈색소치 유지 후 무작위로 피하 및 정맥 주사군으로 나누어 12주간 혈액투석 및 복막투석 환자13명, 28명에서 유효성, 안정성을 분석하였다. 결 과 : 양군에서 혈색소치와 헤마토크릿은 Epokineⓡ 투여 2주 후부터 증가, 혈색소치가 혈액투석 환자는 투여 전 7.3 g/dL, 투여 12주 9.5 g/dL, 24주 10.6 g/dL로, 복막투석 환자는 6.8g/dL에서 12주 10.2 g/dL, 24주 10.8 g/dL로 증가하였다. 양군에서 교정 망상적혈구수(%)는투여 1주 후부터 전 기간동안 증가하였다. 혈청 내 철분, ferritin치는 양군에서 투여 2주 후부터감소, 총 철분 결합능은 투여 2주 후부터 증가하였다. 12주째 혈액투석 환자에서 많은 Epokineⓡ용량이 필요했으나(142.2±20.5 vs 117.3±33.6 U/kg/wk, p<0.001) 24주 후 양군의 용량차이는 없었다(123.6±41.5 vs 99.2±49.3 U/kg/wk, p>0.05). 혈액투석 환자에서 피하 주사가Epokineⓡ 투여용량이 더 적었으나(97.4±15.4 vs 145.4±2.9 U/kg/wk, p<0.002) 복막투석 환자는 차이가 없었다(93.0±60.2 vs 105.4±9.7 U/kg/wk, p>0.05) 연구기간 중 9명(18.8%)에서혈압강하제 추가가 필요한 혈압상승, 근육통 동반 상기도 감염 유사증상 및 두통 등의 부작용이 있었다. 대부분 자연소실 혹은 대증요법으로 치유되었고 2명이 부작용으로 탈락하였다. 결 론 : 말기 신부전 환자의 빈혈 개선에 사용하는 Epokineⓡ의 효과는 복막투석 환자에서 더 좋았으며 투여 경로는 정맥주사보다 피하주사가 높음을 알 수 있었다. Background : We evaluated the clinical efficacy and safety of recombinant human erythropoietin(Epokine^(ⓡ)). Methods : A comparative prospective study of intravenously and subcutaneously administrated Epokine^(ⓡ) conducted 13 patients performing hemodialysis and 28 patients performing continuous ambulatory peritoneal dialysis with end-stage renal disease. Epokine^(ⓡ) was given initially at a dosage of 100 unit/kg, subcutaneously, two times a week. The patients had achieved stable or more than 10 g/dL of hemoglobin level for 12 weeks and then we randomized switching intravenously or subcutaneously administrated Epokine^(ⓡ) for another 12 weeks. Results : Hemoglobin(g/dL) and hematocrit(%) increased significantly from baseline levels beginning from 2 weeks after Epokine^(ⓡ) administration. In HD patients, hemoglobin increased significantly from 7.3 to 9.5 after 12 weeks and to 10.6 after 24 weeks. In CAPD patients, hemoglobin increased significantly from 6.8 to 10.2 after 12 weeks and then 10.8 after 24 weeks(p<0.05). Corrected reticulocyte count(%) was significantly increased from baseline levels beginning from 1 week after Epokine^(ⓡ) administration and continuously increased during study period in both group. Serum ferritin and serum iron decreased significantly and total iron binding capacity increased significantly after 2 weeks. At 12 weeks, HD patients were significantly needed more dosage of Epokine^(ⓡ) than CAPD patients(142.2±20.5 vs 117.3±33.6 U/kg/wk, p<0.001), but at 24 weeks, the dosage was not different(123.6±41.5 vs 99.2±49.3 U/kg/wk, p> 0.05). In HD patients, intravenously administrated Epokine^(ⓡ) group was more dosage than subcutaneously group(97.4±15.4 vs 145.4±2.9 U/kg/wk, p< 0.002), but CAPD patients were not different by administration method(93.0±60.2 vs 105.4±9.7 U/kg/ wk, p>0.05). The 9 cases(18.8%) were suffered from headache and flu-like syndrome, but these side effects were not severe and disappeared from conventional therapy. Conclusion : Epokine^(ⓡ) administration is safe and effective in treating anemia of ESRD patients and subcutaneously administration is significantly more effective than intravenously. (Korean J Nephrol 2002;21(2):190-198)

      • 한국대학생의 도덕사태 개념화 및 그 변화과정에 관한 연구(II)

        송명자,조용하,설기문,김상윤 東亞大學校 學生生活硏究所 1992 學生硏究 Vol.20 No.-

        This study aims to analyze the moral judgmental levels and the conceptions of transgressions of Korean college students in a series of multifacted events and the aspects of change in terms of moral judgmental level and conceptualizastion after with two years' college experience. The study was based on the Kohlberg's cognitive moral development theory and on the domain-distinction model in which children's intuitive abilities are stressed. This study was consisted of two sub-studies done in 1989 and 1991 respectively. The subjects of the 1st year study were 416 college students in four major cities(Seoul, Taegu, Kwangjoo, and Pusan). The subjects of the longitudinal analysis of second year study were 199 college students who could be followed up among the subjects of the 1st year study after two years. The instruments used in this study were Test of Moral Judgmental Development and Test of Conceptualization on Mulifaceted Events developed by the authors on the basis of Kohlberg's and Turiel's theories respectively. The following conclusions were obtained through the basis of the results and discussions of this study. First, Korean college students' false responses to moral issues decrease but the radical and anti-social responses increase after two years, and ther these responses are replaced by the level Ⅲmoral judgmental responses. Second, college students who are on the higher moral judgmental level conceptualize the transgression in social conventional and personal domains less permissible than those on the lower levels do. The students who are on the lower judgmental level reveal the decrese of nonpermissibility in social conventional domain with two years' college experience than those on the higher level do.

      • Ca^(2+)―작동성 Cl^-전류에 미치는 이차 전령들의 효과

        송인섭,이무열,방효원,엄대용,이상돈 중앙대학교 의과대학 의과학연구소 1993 中央醫大誌 Vol.18 No.3

        The anion movements across the cell membrane were regarded as apart of passive distribution according to the cation movements. Recently, from the developement of patch clamp technique new concept for anion channels were introduced. And their roles in the genesis of action potential and resting potential were noticed. So we clarified the existence of the chloride channel in the smooth muscle cells and studied its nature in regard to the roles of the second messangers. We used the whold cell voltage clamp technique to study the current responses induced by carbachol application in the circular smooth muscle cells of the gastric antrum of the rabbit. The results were as follows; 1. Application of the carbachol induced the increase of inward currents in the hyperpolarized potential ranges, and the increase of outward currents in the depolarized ranges. 2. Even in the cases of blocking all the known currents, these current components were observed. 3. Sodium ion removel from the external medium rarely affected these current responses, and the addition of cadmium ion did not make any remarkable change. 4. Known second messangers such as c-AMP, c-GMP, heparin, A1F_4 rarely affected these current components. 5. Lowering of intracellular calcium ion concentration drastically reduced these current responses. Form the above results we can suggest that the carbachol induced current responses contained chloride currents which were activated by only intracellular calcium ion, not by any other second messegers in the gastric antral smooth muscle cells.

      • 경구면역을 통한 항원 특이적 IgA 항체 합성에 있어 Cholera Toxin과 Alginate-Microsphere의 효과

        송민형,유진수,권명상,성승룡,김용희,권익찬,정서영,양재명,김평현 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.3

        Secretory (S-IgA) isotype antibody (Ab) is known to play an essential role in the primary defense against various infectious agents in mucosal tissue. However, it has been mostly unsuccessful in the induction of antigen (Ag)-specific IgA Ab response in this site by peroral vaccination. In the present study, we investigated the effect of cholera toxin (CI) as a mucosal adjuvant and alginates-microspheres as a carrier on BSA-specific IgA Ab response in gut-associated lymphoid tissue`(GALT). Peroral immunization of BSA plus CT conferred a great BSA-specific IgA response but IgG response on intestinal fluid (IF). In contrast, intraperitoneal immunization of BSA with Freund's adjuvant readily induced BSA-specific IgG response but IgA response in IF. Further, number of CT specific IgA-secreting cells was substantially increased in mesenteric lymph node when CT-encapsulated-VI alginates-microspheres was administered perorally. Taken together, these results indicate that peroral immunization of soluble antigen in combination of CT or microspheres significantly enhances antigen-specific IgA response in GALT.

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