늑막삼출액을 동반한 다발성골수종 1예

김용화,주기산,서영환,조경상,김상도,정춘해 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.2

Pleural effusion in a patient with multiple myeloma due to plasma cell involvement of the pleura has been reported infrequently. We report a case of multiple myeloma with pleural involvement presenting bone pain and dyspnea in a 69-year-o1d woman. On the physical examination, the patient looked chronically ill with bedridden state. There was a palpable mass on the left posterior lower chest, firm but not tender and decreased breathing sound in the left lower lung. Laboratory finding revealed amemia, elevation of ESR, globulin, and calcium. X-ray of the chest showed pleural effusion in the left lower lung, and multiple pathologic fractures in the both ribs. X-ray of the skull, and pelvis revealed multiple punched-out osteolytic fractures in the both ribs. X-ray of the skull, and pelvis revealed multiple punched-out osteolytic lesion, and compression fracture in the lumber spine. Serum and urine electrophoresis revealed a M-spike. Serum and urine immunoelectrophoresis demonstrated an IgA-kappa monoclonal protein. Thoracentesis revealed serosanguinous fluid but not containing atypical plasma cells. Bone marrow examination showed 16.7% of immature plasma cells. With first cycle of melphalan, prednisone chemotherapy, improvement of pain and disappearance of pleural effusion was observed.

분지 폴리카보네이트 합성 및 반응 특성 연구

김환기,김상필,김선호 건국대학교 자연과학연구소 1998 建國自然科學硏究誌 Vol.9 No.1

The branched polycarbonate was prepared from bisphenol A and trihydroxphenyl co-monomers in batch reactors. The polymerization was based upon phosgenation, followed by condensation with triethylamine as a catalyst. The polymers were characterized by differential scanning calorimetry(DSC), gel permeation chromatography(GPC), and thermogravimetric analyses(TGA). The relative kinetic studies of branched polycarbonate system that in polycondensation steps the reaction rates are more dependent on the content of branching agent than the corresponding linear polycarbonate. These results illustrate the branched polycarbonate was predominantly formed cyclic oligomers in terms of trihydroxyphenyl comonomer. The melt index ratio(MIR) of branched polycarbonates obtained was in the range of 20~25, which are compatible with application of blow molding.

관동맥 재개통 후 QTc간격분산의 감소 : 정량적으로 측정한 심근 허혈의 호전 정도와의 연관성 Relationships with the Quantitative Degree of Improvement in Myocardial Ischemia

박상선,최기준,남기병,이철환,홍멸기,박성욱,박승정,신중우,문대혁,김유호 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

청소년의 컴퓨터게임 이용실태, 부모양육방식, 개인의 정신병리

전성일,류정환,김영미,정홍경,조아라,이정호,최영민,이기철 대한소아청소년정신의학회 2000 소아청소년정신의학 Vol.11 No.1

연구목적 : 오늘날 컴퓨터게임은 청소년기의 보편적 놀이도구가 된 상황임에도 불구하고 이들이 게임에 몰두하는 이유와 개인특성에 관한 정신과적 연구는 드문 실정이다. 이러한 필요성에서 본 연구는 중학교 2년 생을 대상으로 청소년의 컴퓨터게임 사용실태를 파악하고, 연관된 개인정신병리와 부모의 양육방식과의 관계를 밝히고자 하였다. 방법 : 이 연구는 서울시 노원구에 위치한 중학 2년생 124명을 대상으로 하였다. 정신병리의 측정을 위하여 한국판 간이정신진단검사(SCL-90-R)을 사용하였고, 부모자녀 결합형태 조사(PBI)를 통하여 부모양육태도를 알아보았다. 결과 : 1) 비록 과도한 시간을 들여 컴퓨터게임을 하더라도, 컴퓨터게임과 연관된 특정 정신병리는 발견할 수 없었으며 따라서 콤퓨터게임은 청소년기에 있을 수 있는 일상적인 놀이문화이다. 또 한대 부분의 청소년은 컴퓨터게임이 문제가 되지 않는다고 인신하고 있었다. 2) 남학생은 게임빈도, 게임시간, 게임방에서 보내는 시간, 게임을 한 번 할 때 지속하는 시간 등에서 여학생에 비해 통계적으로 의미 있게 높은 수치를 보였다. 3) 청소년의 신체증상호소, 타인간의 관계에서 나타나는 불편감, 우울증, 불안증의 정신병리는 컴퓨터 오락으로 인한 부작용과 의미 있는 관계를 보였다. 4) 게임빈도와 FBI상의 어머니 과보호척도는 정적인 상관관계를 보였다. 5) 게임을 하는 이유로는 공부, 학교 생활 등의 복잡한 것을 잊고 몰두하기 위해가 가장 많았고, 가장 심리적으로 부담이 되어 피하고 싶은 것으로는 학업문제였다. 6) 청소년은 게임방을 주로 친구들과 어울리는 공간으로 사용하고 있었지만 그 기능을 다하기에는 아직 보완해야 할 점이 많다. 결론 : 게임으로 인한 부모, 교사와의 다툼, 잦은 지각/결석, 친구들과 어울리지 못하는 등의 문제가 많은 경우에는 청소년 자체의 정신별리를 의심해 보아야 하며, 게임의 빈도가 의미 있게 높은 청소년의 경우에는 둥반되는 정서상의 문제와 함께 부모양육태도도 함께 세심하게 살피는 것이 필요하다. Objects : This study was designed or studying of current Korean adolescents computer game playing habits and exploring associations with parental rearing patterns and individual psychopathology. Methods : One hundred twenty our adolescents(age 13-15) who reside in urban area completed self-report questionnaires containing Questionnaires designed by authors, Symptom Checklist-90-Revision of Korean Version(SCL-90-R) and Parental Bonding Instrument(PBI). Results : 1)Computer game playing appears to be one of the social and leisure phenomena in these days. Although Adolescents spend a lot of times on computer game, Many of them perceive not problematic. 2)Compared with females, Male play computer games more regularly, more longer, spent more times in gamebang. 3)There was positive relationship between anxiety subscale in SCL-90-R and detrimental effects of computer game. 4)There was positive relationship between game frequency and maternal overprotection. 5)The main reasons for playing are "for an avoidance of stressful life events" , academic burden was the most troublesome issues in korean adolescents. 6)Many adolescents use gamebang as a social place, but they thought that gamebang is not good places to have a good time. Conclusion : This papers shows that computer game playing is a popular social leisure activity in Korean adolescents. And, Most of korean adolescents reported that they are suffered from pressure of academic achievements. They use computer game mainly by means of relieving academic pressures. In a heavy game users who have many conflicts with parents, teacher and who has frequent truancy and social withdrawal show significant anxiety. Maternal overprotection was observed in heavy game users. Authors recommended that clinicians should be careful in examining heavy computer game behaviors. Both underlying affective states and environmental influences, including family situations should be vicariously examined. KEY WORDS : Computer game · Gamebang · Game habits · Psychopathology · Parental rearing pattern.

Solution Vicosity and Relative Reactivity of Branched and Linear Polycarbonates

Kim, Sang Hern,Kim, Whan Gi,Kim, Sang Pil,Lee, Bong Hee 한국유화학회 2000 한국응용과학기술학회지 Vol.17 No.2

The relative reactivities of branched and linear polycarbonates were investigated by measuring unreacted chloroformate concentration. It was found that the polymerization for the branched polymer proceeded ca. 10 times faster than that for the linear polymers. The effect of catalyst on a condensation step was studied by changing the amount of TEA (triethylamine) at t_0 and t_60 with keeping constant amount of TEA. The viscosity average molecular weight for the obtained branched polycarbonates were measured and compared with those of linear polycarbonates. It was found that the viscosity molecular weights of the obtained polymers decreased nonlinearly as wt % of added oligomer increased. The solution viscosities in methylenechloride for linear and branched polycarbonate increased nonlinearly as the content of polymer increased.

Dual lipid lowering therapy may be correlated with HDL-C reduction in follow up period in acute myocardial infarction patients (초)

( Gi Hyun Kim ),( Ju Hee Lee ),( Sang Min Kim ),( Sang Yeub Lee ),( Jang Whan Bae ),( Dong Woon Kim ),( Myeong Chan Cho ) 대한내과학회 2010 대한내과학회 추계학술대회 Vol.2010 No.-

Ethyl Alcohol Extracts of Hizikia fusiforme Sensitize AGS Human Gastric Adenocarcinoma Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Mediated Apoptosis

Kim, Tae-Yeon,Jin, Cheng-Yun,Kim, Gi-Young,Choi, Il-Whan,Jeong, Yong-Kee,Nam, Taek-Jeong,Kim, Se-Kwon,Choi, Yung-Hyun The Korean Society of Food Science and Nutrition 2009 Journal of medicinal food Vol.12 No.4

Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis has been reported in some cancer cells, including AGS human gastric adenocarcinoma cells. Hizikia fusiforme is a commonly used brown seaweed species in Korea that possesses potent antibacterial, antifungal, and anti-inflammatory activities. In this study, we demonstrated that treatment with TRAIL in combination with subtoxic concentrations of ethyl alcohol extract of H. fusiforme (EAHF) sensitized TRAIL-resistant AGS cells to TRAIL-mediated apoptosis. Combined treatment with EAHF and TRAIL increased chromatin condensation, DNA fragmentation, and sub-G1-phase DNA content. The restored sensitivity to TRAIL-induced apoptosis appeared to be correlated with the modulation of Bcl-2 family proteins and activation of caspases, which resulted in the cleavage of poly(ADP-ribose)polymerase. Taken together, the use of EAHF in combination with TRAIL may be an effective and selective anticancer strategy via suppressing the resistance to TRAIL-induced apoptosis in some tumor cell lines, including AGS cells.

A Sequence Polymorphism in Myostatin(MSTN) Gene of Halla Riding Horses in Jeju Island

Kim Yun gi,Song Jung Whan,Kim So Yeon,Lee Kyung Kap,Yun Young Min 대한수의학회 2014 대한수의학회 학술대회발표집 Vol.2014 No.-

Solution Viscosity and Relative Reactivity of Branched and Linear Polycarbonates

Kim, Sang-Pil,Lee, Bong-Hee,Kim, Sang-Hern,Kim, Whan-Gi The Korean Society of Applied Science and Technolo 2000 한국응용과학기술학회지 Vol.17 No.2

The relative reactivities of branched and linear polycarbonates were investigated by measuring unreacted chloroformate concentration. It was found that the polymerization for the branched polymer proceeded ca. 10 times faster than that for the linear polymers. The effect of catalyst on a condensation step was studied by changing the amount of TEA (triethylamine) at $t_{0}$ and $t_{60}$ with keeping constant amount of TEA. The viscosity average molecular weight for the obtained branched polycarbonates were measured and compared with those of linear polycarbonates. It was found that the viscosity molecular weights of the obtained polymers decreased nonlinearly as wt % of added oligomer increased. The solution viscosities in methylenechloride for linear and branched polycarbonate increased nonlinearly as the content of polymer increased.

Is the Oscillometric blood pressure measuring device in accord with the intra-arterial invasive blood pressure measuring method ?

Kim, Gi Hyun,Joo, Hye Jin,Lee, Won-luk,Lee, Ju-Hee,Lee, Sang Yeub,Bae, Jang-Whan,Hwang, Kyung-Kuk,Kim, Dong-Woon,Cho, Myeong-Chan 충북대학교 의과대학 충북대학교 의학연구소 2010 忠北醫大學術誌 Vol.20 No.1

Purpose: Hypertension is closely related to the occurrence and aggravation of major incidents in cardiovascular system. However, there is not much elucidated about the accordance of blood pressure (BP) measurement with oscillometric device and invasice BP from patients having the risks of cardiovascular disease. We have checked the accordance of non-invasive BP using the oscillometric device in comparison with invasive BP through redial artery catheter in performing coronary angiography. Subjects and methods: We compared the BP measured through redial artery and electronic sphygomanometer (Omron HEM-747IC, Japan) from the brachial for 104 patients who had gone through coronary artery angiography by visiting Chungbuk university hospital from September, 2007 till April, 2008. Results: The BP measured with oscillometric device was mostly in accordance with invasive BP for all systolic, diastolic and average BP. However, the group of stage 1 hypertension by the standards of Seventh Report of the Joint National Committee showed low accordance between the two methods in diastolic BP. For non hypertension group and pre-hypertension group, systolic BP showed a pattern where systolic BP was underestimated, but for the first and second stage hypertension groups, the BP measured with oscillometric device displayed an overestimated patten Conclusion: Most of the blood pressures measured with automated sphygomanometer showed good agreement with invasive BP. However, it needs attention in using because the diastolic BP is not in accordance with invasive BP form the first stage hypertension patients. 연구 목적 : 고혈압은 심혈관계 주요사건 발생과 악화에 밀접한 관계가 있다. 그러나 아직까지 심혈관 질환의 위험성을 가진 환자에서 전자 혈압계를 통한 혈압 측정과 침습적 혈압과 일치여부에 대해서 잘 밝혀진 바가 없다. 우리는 관상동맥 조영술을 실시하면서 노동맥 도관을 통한 침습적 혈압과 비교하여 전자열합계를 이용한 비침급적 혈압의 일치도를 확인하였다. 대상 및 방법 : 2007년 9월부터 2008년 4월까지 충북대학교 병원을 방문하여 관상동맥 조영술을 시행 받은 104명의 환자들을 대상으로 노동맥을 통한 혈압 측정과 상완에서 전자 혈압계 (Omron HEM-747IC, 일본)로 측정한 혈압을 비교하였다. 결과 : 자동 혈압계로 측정한 혈압은 대체로 수축기, 확장기 및 평균 혈압 모두 침습적 혈압 값과 일치하였다. 그러나 Seventh Report of the Joint National Committee 기준으로 1단계 고혈압을 갖는 집단은 이완기 혈압이 저평가되는 양상을 보였으니 1단계 및 2단계 고혈압 군에서는 자동 혈압계로 측정한 혈압이 고평가되었다. 확장기 혈압 및 평균 혈압은 모든 단계에서 고평가 되는 양상을 보였다. 결론 : 자동 혈압계로 측정한 혈압의 대부분은 침습적 혈압과 좋은 일치도를 보인다. 그러나 1단계 고혈압 환자군에서는 확장기 혈압이 침습적 혈압과 일치하지 않으므로 사용에 주의가 필요하겠다.