Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

홍민어 Sciaenops ocellatus에서의 바이러스성 신경괴사증 viral nervous necrosis

김진도,김석렬,정성주,김영진,정태성,최태진,박성우,오명주 한국어병학회 2001 한국어병학회지 Vol.14 No.2

1999년 10월에서 11월 사이에 남해안 일대의 홍민어 종묘 생산장에서 20~30열령의 치어가 척추만곡 및 이상유영을 하며 대량 폐사하였다. 병어는 특이 외부 증상이 없었고, 높은 누적폐사량이 바이러스 질병으로 의심되어, 조직학적 및 분자생물학적인 검사를 행하여 폐사원인을 확인하였다. 폐사개체의 조직을 H-E 염색하여 관찰한 결과 뇌와 안구의 신경세포에서 공포와 괴사가 관찰되었고, 전자현미경 관찰에서는 안구와 뇌에서 바이러스 입자가 관찰되었다. RT-PCR 결과에서는 ≒426 bp의 DNA 단편을 확인할 수 있었다. 이러한 결과로 홍민어에서 발생한 대량폐사는 바이러스성 신경괴사증(VNN)으로 진단되었다. Mass mortalities occurred among red drum lavae, 20 to 30 days old, culturing at hatcheries on southern costal area. No specific external signs were observed except abnormal swimming and spinal deformity. It was, however, suspected as a viral etiology due to high mass mortalities so that histopathological and molecular biological study was performed to evaluate the agent. Both vacuoles and necrosis were observed on nerve cells of brain and eye by H-E staining, and viral particles were observed on electronmicroscopic examination. On the other hand, DNA fragment, approximately 426 bps, was amplified with RT-PCR. The above results were able to diagnosis the etiological agent of mass moralities in red drum larvae as VNN(viral nervous necrosis)virus.

상수처리 시스템에서의 막분리 공정의 개발

오중교,이태진,정두식,이용택 경희대학교 환경연구소 1995 環境硏究 論文集 Vol.6 No.-

Membrane filtration process seems to have many advantages such as improvement of drinking water quality, saving water purification chemicals and operation cost, easier operation and maintenance and saving time and cost for construction of a water purification plant. A study was conducted to optimize the use of a membrane process to produce potable water from Lake water in singal, Kyungkido, South Korea. We try to optimize the process by adjusting different pretreatment, various MWCO(Molecular Weig염(salt), alignate와 같은 천연고분자 또는 ht cut-off), hydrauric conditions.

鷄胚의 十二指腸 粘液細胞에 미치는 4 Nitroquinoline 1-Oxide의 影響

吳鎭泰,韓春培,河在淸 부산교육대학교 과학교육연구소 1982 科學敎育硏究 Vol.7 No.-

This experiment was performed to observe the histochemical properties of the mucosubstances in the duodenum of chick embryos and the effect of 4NQO 5x10^-6M and 4NQO 5x10^-7M on the goblet cells of the chick embryo's duodenum. The chick embryos, which was used for this experiment, was seperated into five stages in the process of their developing; 16 day-embryos, 18 day-embryos, 20 day-embryos, 21 day-embryos and 9 day hatched chick. The mucosubstances were stained with Alcian blue pH2.5-PAS, Periodic Acid Schiff(PAS) and Alcian blue pH2.5-Azure. The obtained results were as follows; 1. The histochemical compositions and amounts of mucosubstances in the goblet cells of Chick embryo's duodenum were observed to consist of acid and neutral mucins. 2. The acid neutral mucin's cells were observed to increase in number more in the others long-day chick embryo than 16 day chick embryo in the process of their developing. 3. The histochemical compositions and amounts of mucosubstances in the goblet cells were didn't have the portion differences, but were showed less in the crypt goblet cells. 4. Though 4NQO 5x10^-6M and 4NQO 5x10^-7M had been injected into chick embryo, the histochemical compositions and amounts of mucosubstances in the goblet cells, and their structure of villi were not varied in particular.

자연과에서의 협동적 포트폴리오 작성활동과 효과

오진태,임채성,권해성 부산교육대학교 과학교육연구소 1998 科學敎育硏究 Vol.23 No.-

This study examined the influences of cooperative construction of portfolio about some concepts in life science in the elementary school. These included four concepts of classification of living organism, comparison, ecosystem, and adaptation to environment. Cooperative activities in the construction of portfolio facilitated the acquisition of correct concepts. Especially, highly significant difference in the area of classification of living things appeared between the traditional and cooperative portfolio groups. When we compared the four concepts, the scores of cooperative group about correct concepts were higher than those of individualistic group. It was revealed that the individualistic construction limited the interaction among children, and children and teacher, while the activities of cooperative construction portfolio activated reflective thinking of children. These results suggest the importance of active and various interaction among children-children and children-teacher. There were no significant differences between the individualistic and traditional groups. As the interaction among children-children and children-teacher activated, it became general trends that children corrected, modified, or complemented their portfolios and became more enthusiastic in such activities. Whole results implied that cooperative and interactive activities have positive influences in the acquisition of correct science concepts.

Identification of a Gene Cluster in Streptomyces spectabilis-spectinomycin producer

오태진,김형준,송재경 선문대학교 대학원 2000 대학원학술논문집 Vol.2 No.-

Spectinomycin (Spc) is an aminoglycoside antibiotic which shows remarkable broad-spectrum. From a chromosomal cosmid library of Streptomyces spectabills, a Spc producer, a clone (pSPM8) was isolated by homology to the dTDP-glucose 4,6-dehydratase and aminotransferase genes which obtained from S. spectabilis genome using a polymerase chain reaction. From this clone, a 5.8-kb DNA region was sequenced and found to encode four open reading frames and one Incomplete reading frame. The putative orfl protein reveals 29% amino acid sequence homology of putative myo-inosltol-2-dehydrogenase from Vibrio anguillarnm. The orf2 is about 46% homologous to putative myo-inositol-1-monophosphotase of Mycobacterium leprae. The orf3 showed strong homology (67.4%) to putative export protein (spcT) from S. flavopersicus. The amino acid sequence deduced from 0114 showed a high similarity (70.8%) to a spectinomycin resistance gene (spcN) from S. flavoperslcus. Expression of orf4 in E. coti BL21 showed the spectinomycin resistance.

수분 조건에 따른 수종 식물의 기공 분포 변화

오진태,임채성 부산교육대학교 초등교육연구소 1995 초등교육연구 Vol.6 No.-

This study examined the changes of stomatal distribution(density, frequency) in a few plants with the variation of changes in soil-water. Commelina communis L., which is one of C_3 plants, have anomocytic type of stomata. Digitaria sanguianalis Scop. which belongs to C_4 plants, and Portulaca oleracea L. which is CAM plants, have paracytic, and anisocytic types of stomata, respectively. In C. communis L., the stomatal size of upper side of leaves was greater than that of lower parts. In both of D. sanguianalis Scop. and P. oleracea L., this trend was opposite. As the moisture in soils decreased, the stomatal size was decreased. The stomatal densities in these three species were greater in lower sides than those of upper sides. Finally, the stomatal densities of these plants showed trends of more stomata per unit area as the moisture of soil decrease. These results suggest that the plants adopt the efficient water-use strategies.

國民學校 自然科實驗學習 指導 : 플라나리아의 실험

吳鎭泰 부산교육대학교 과학교육연구소 1984 科學敎育硏究 Vol.9 No.-

This study is to suggest the teaching method of the experimental material "Planaria" in primary school science course. This is as follows, 1. Collection and breeding methods of planaria 2. Observation of external structure and gut branch 3. Irritability and taxis of planaria. 4. Observation of regeneration. autotomy and diminution.

만화 과제를 이용한 정신분열병 환자의 사회인지 능력의 측정

오정은,나명현,하태현,신용욱,노규식,홍순범,이경진,신민섭,이영호,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : This study is to investigate the hypothesis that schizophrenic patients have difficulty in inferring mental state of others. Methods : Twenty schizophrenic patients and twenty normal subjects were administered to the Cartoon Task required inferring the character's intention in a given context. Results : The schizophrenic patients showed a statistically significant impairment in the Cartoon Task. Both groups chose the card depicting a frequent everyday action significantly more rather than the similar card to the last picture in each story for wrong answers. Conclusion : These preliminary results suggest that schizophrenia is associated with a specific deficit of the cognitive ability referred to as social cognition, and this deficit can be detected not only in the acute phase as found in previous research studies, but also in remission. Also when subjects fail to appreciate what is going on in the minds of other people, they seem to rely on a socially familiar experience.

유치우식의 관련요인에 대한 연구

오명희,김진태 大韓小兒齒科學會 1982 大韓小兒齒科學會誌 Vol.9 No.1

The author has compared and analized contributing factors which affect 155 5-year-old childrens who reside in SEOUL with caries involvement by means of oral inspection and questionaire. The results are as follows. 1. Children sucking human milk had more decayed teeth than those who sucking bovine milk. (P<0.05) 2. Children performing the toothbrushing everyday had fewer decayed teeth than those who performing that occasionally. (P<0.05) 3. Children eating the weaning diet late had more decayed teeth than those who eating that earlier. (P>0.05) 4. Children sucking milk bottle besides milk had more decayed teeth than those who sucking milk bottle only with milk. (P>0.05) 5. Children not using milk bottle had more decayed teeth than those who always using that. (P>0.05) 6. Children eating between meals up to time has fewer decayed teeth than those who eating between meals whenever possible. (P>0.05) 7. Children eating the sugar containing food well had more decayed teeth than those who eating the meal ordinarily. (p>0.05)