Expansin 유전자를 이용한 담배의 형질전환과 형질전환체 선발

백승준, 김보미, 장종오, 엄유리, 석영선, 이이 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

-본문참고-

진균성 부비동염의 임상적 고찰

이승원,김장욱,박영진,송태현,이병돈,장혁순 순천향의학연구소;Soonchunhyang Medical Research Institute 2000 Journal of Soonchunhyang Medical Science Vol.6 No.1

The fungal sinusitis is relatively rare and mainly develops in immunocompromised hosts, but is sporadically appears in the immunocompetent patients, where its incidence tends to be increasing. Because the clinical features of this disease are similar to those of chronic suppurative sinusitis, this entity may be overlooked. We analysed thirteen fungal sinusitis from January 1997 through December 1999 based on clinical features, laboratory characteristics and operative findings. The results are as follows. 1)Fungal sinusitis occurred 3.3 times as frequently in female patients as in male patients and the peak age groups are 4th and 5th decades. 2) The time intervals between the onset of symptoms and the first hospital visit were as follows: 5 cases within 3 months, 1 case between 4 and 6 months, 3 cases between 7 and 12 months, and 4 cases over 1 year. 3) The chief complaints were nasal obstruction, postnasal drip, rhinorrhea, cheek pain, headache, ocular pain, sneezing. 4) The characteristic computerized tomographic findings were hyperattenuated lesions in the maxillary sinus and in the nasal cavity near the natural ostium. 5) The most common pathogen was Aspergillus(92.3%) 6) We performed Caldwell-Luc's operation only in 4 cases, Caldwell-Luc's operation with intranasal ethmoidectomy in 3 cases, Caldwell-Luc's operation with endoscopic sinus surgery in 3 cases and endoscopic sinus sugery only in 3 cases. 7) Most of the gross specimens revealed a fungus ball containing a black-brown necrotic debris or caseous material.

영․유아 그림 표상 특성에 관한 연구

이승옥,최은영,임지향 대구대학교 특수교육재활과학연구소 2005 再活科學硏究 Vol.23 No.2

The purpose of this study was to refer a symbolic characteristic of painting during scribbling period by applying a task condition, to present basic data about effective symbolic painting by analyzing a process of a construct activity, and to examine verification of effectiveness in the Korean infant. The one way anova is carried out to find out a symbolic characteristic of painting of Age(4)X group and the two way anova to Group(2)×Age(4), is conducted to figure out the difference of NC performance owing to task presented type upon age bracket. The followings were ostensive purposes of this study. First, there would be differences in symbolic characteristic by tasks and ages(the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). Second, the NC performance would differ in symbolic characteristic by age and painting type(the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). The study participants were randomly selected one - three years old infants (total of 80) who attend in an infant home in northern Daegu. They were divided in four groups. Each age group was presented two type of painting and multivariate analysis was taken in order to compare and analyze paintings. The result of this study was followed. First, the characteristic of painting symbol was different by task and age. The expressive ability in total score, constituent of object, pair symbolic in P task and DC task was increased as aging. Among the group of infants aged 1.5 - 2.5, P task was performed better than DC task, and the score of P task and DC task was equally heightened as they become age of 3. Second, NC performance owing to task presented type upon age bracket would be different (the total score, the score of symbol inside the outline, the score of constituent, the score of pair symbolic). The older has shown more expressive ability in two type of painting. NC task was taken after pre- P task and -DC task, but the symbolic score of NC task differed from. NC task followed by P task represented the more constituents and pair symbols than by DC task. Therefore, this study found out that the development of symbolic level in infant had close relationship with an age, the symbolic abilities in different painting tasks differed order of P task, DC task, and NC task, and symbolic painting was shown from infant age 1.5-2. 본 연구는 초기 그림 표상 출현과정을 살피기 위한 것으로 구체적인 가설은 다음과 같다. 첫째, 과제별 연령에 따른 그림 표상의 특성(총점수, 윤곽선 안의 표상의 점수, 대상의 구성요소 표상의 점수, 쌍표상의 점수)은 차이가 있을 것이다. 둘째, 연령별 과제 제시유형에 따른 NC과제 수행(총점수, 윤곽선 안의 표상의 점수, 대상의 구성요소 표상의 점수, 쌍표상의 점수)은 차이가 있을 것이다. 연구대상은 00시에 위치한 어린이집에 재원중인 1-3세 유아 총80명을 무선선정하여 연령별로 4집단을 나누고 각 연령집단별로 두 그룹으로 나누어 서로 다른 유형의 과제를 실시하였다. 즉 한 그룹은 P과제 이후 NC과제를 실시하였고, 다른 한 그룹은 DC과제 이후 NC과제를 실시하였다. 과제실시 이후 각 과제에서 얻어진 표상그림을 채점하였다. 자료처리는 과제별 연령에 따른 그림표상의 특성을 살펴보기 위해 연령(4)x집단간의 일원 다변량분석을 실시하였고, 연령별 과제 제시유형에 따른 NC과제 수행의 차이를 보기 위하여 집단(2)×연령(4)에 대하여 2원 다변량분석을 실시하였다. 본 연구의 결과를 요약하면 다음과 같다. 첫째, 과제별 연령별에 따른 그림 표상의 특성은 차이가 있다. 연령에 따라 P과제 또는 DC과제 모두가 총점수, 대상의 구성요소, 쌍표상의 표현능력은 연령이 높음에 따라 표상능력이 증가함을 알 수 있었다. 1.5세-2.5세에서는 P과제가 DC과제보다 훨씬 잘 수행했으며 3세가 되면서 P과제와 DC과제 점수가 같이 높아졌다. 둘째, 연령별 과제 제시유형에 따른 NC과제 수행은 차이가 있다. 연령이 증가 할수록 과제 제시유형에서 과제의 표상 능력도 증가하였다. 연령에 따라 P과제 선행 후 NC과제와 DC과제 선행 후 NC과제의 표상의 점수는 다르다. P과제 선행 후 NC과제가 DC과제 선행 후 NC과제에서 보다 더 많은 대상의 구성요소, 쌍표상을 표현한 것으로 나타났다. 따라서, 본 연구를 통해 유아의 표상 수준의 발달은 연령과 밀접한 관계가 있고 과제에 따른 그리기 표상능력도 P과제, DC과제, NC과제 순으로 일어나며, 표상적 그리기가 1.5세와 2세경에 시작된다는 것을 보여준다.

강원지역 중소기업의 환경경영 실태와 과제

전영승,박은정 한국산학경영학회 2004 산학경영연구 Vol.17 No.1

본 연구의 목적은 ISO14001 인증 취득 현황조사를 통해 강원지역 중소기업의 환경경영 실태와 과제를 파악하고 환경경영의 활성화를 위한 방안을 모색하는 것이다. 주요 결과를 요약하면 다음과 같다. 첫째, 2003년 4월 현재 우리나라의 ISO14001 인증획득 업체수는 1,215개 업체인데 비해 강원지역 중소기업의 ISO14001 인증획득 업체는 광역지방자치단체 중 최하위 수준인 26개 업체에 불과하였다. 둘째, 인증 미획득 기업들이 인증을 받지 않으려는 이유로 '인증 획득 및 유지에 소요되는 비용이 효익보다 크다'는 점을 제시하였다. 셋째, ISO14001 인증을 획득한 기업이나 ISO14001 인증 미획득 기업이나 인증을 획득한(하려는) 가장 큰 이유는 '기업의 이미지 향상'이었으며, 인증 획득기업이 환경경영시스템 도입 후 얻은 효과도 '기업의 이미지 향상'으로 나타났다. 넷째, ISO14001 인증을 획득한 기업들은 환경경영시스템을 도입할 때 문제점으로 '문서작성 및 비용에 관한 부담'과 '인력 부족'에 관한 응답이 많았다. 위와 같은 연구의 주요 결과를 바탕으로 강원지역 중소기업의 환경경영 활성화를 위한 과제와 방안을 제시하면 다음과 같다. 첫째, ISO14001 인증 미획득 기업 대부분이 ISO14001에 대한 인지도가 낮아 이에 대한 지속적이고 적극적인 홍보와 교육 및 연수제도가 필요하다는 점이다. 둘째, 환경경영 관련 인력이 부족함으로 전문 인력의 양성을 위한 교육프로그램의 실시, 보조금 지급의 확대, 상담부서 및 상담창구의 개설, 관련 정보의 데이터 베이스화나 소프트웨어의 개발이 필요하다. 셋째, 저렴한 비용과 간단한 절차를 통해 인증을 받을 수 있는 중소기업용 공적 인증제도의 신설, 혹은 단체인증제도, 공단 인증제도 등을 적극 고려할 필요가 있다. The purpose of this study is to understand the realities and the subject of environmental management for small and medium-sized companies in Gwangwon area, through surveying the present status as to acquiring the certification of ISO14001, and to seek for a plan to facilitate environmental management. Given summarizing key results, those are as follows. First, while the number of companies in our country which acquired the certification of ISO14001, amounts to 1,215 businesses as of April of 2003, the number of small and medium-sized companies in Gwangwon area which obtained the certification of ISO14001 reached only 26 businesses, the lowest level among metropolitan municipalities. Second, for the reason that companies who didn't acquire the certification, strive not to receive the certification, it did present the point that 'costs to be needed in acquiring and maintaining the certification are larger than practical benefit. Third, the biggest reason for either companies which did not acquire the certification of ISO14001 or companies which did (try to) acquire the certification of IS01400, was 'enhancement of a corporate image,' and the effect after a company who obtained the certification introduced the environmental management system, was also shown to be 'the improvement of a corporate image.' Fourth, many companies who acquired the certification of IS01400 pointed out the response related to 'burden on document creation and costs' and 'lack of manpower' as problems when introducing the environmental management system. On the basis of major results of a study as the above, given presenting the subject and a plan for activating the environmental management of small and medium-sized companies in Gwangwon area, those are as follows. First, because most of companies who did not obtain the certification of IS01400 have low recognition of ISO14001, it needs continuous and positive publicity, education and a training system. Second, it requires to carry out an educational program to nurture professional manpower due to lack of manpower relevant to environmental management, to expand payment of subsidies, to open exclusive-charge department and consulting contact, to have the relevant information be database and to develop software. Third, in order to make the certification obtained through inexpensive costs and simple procedures, it needs to positively consider the creation of public approval system for a small and medium-sized company, group approval system, industrial-complex approval system, and others.

우리나라 부동산등기제도의 개선방안에 관한 연구

최승영 대한민사법학회 2004 민사법연구 Vol.12 No.1

Modernistic real-estate registration system has worked about a century in Korea, but it was no match for the ideal of safety and promptitude of transactions in realty. Especially, a matter of consequence is that our country doesn't authorize public confidence of registration. In this study, I'll check the problems of registration system compared with that of foreign countries and investigate general theories. Besides, I will also check the improvement and aim to search for the alternatives that can be genuine real-estate registration. This study is based on a literature analysis, data from internet site, and an interview with the registry officials. In order to solve those problems, the study suggests the systematic amend in the registration related laws, after resurvey of cadastral lands, the unification of the varied register books and cadastral records and enforces the authentication system of registration cause certificate. In addition, it is necessary to improve public confidence of registration, the upgrade and specialization of its officials and computerization of the registry tasks, improve the registry proxy application system. In conclusion, it is desirable to seek the safety of transaction and recognize public confidence of registration on a condition that system is improved.

장기 이식 환자에서 Voriconazole 과 Cyclosporine 또는 Tacrolimus의 상호작용

한혜원,김재연,송영천,김승은,유성길 한국병원약사회 2009 병원약사회지 Vol.26 No.1

Abstract: In organ transplant patients, the opportunity of fungi infections such as invasive aspergillosis increase by use of immunosuppresant drugs and voriconazole is recommended as primary treatment drug. When voriconazole is administered with cyclosporine(CsA) or tacrolimus(FK506), caution about increment of blood CsA or FK506 concentrations that caused by the change of CYP3A4 activity is required but few domestic cases of interaction were reported yet, The purpose of this study was to assess the effect of voriconazole on the blood CsA or FK506 concentrations in transplant recipients and the factors of recipients that have an effect on the results. 25 transplant recipients who were administered voriconazole with CsA or FK506 from January 1 of 2006 to August 17 of 2008 in Asan Medical Center were objects (12 patients on CsA coadministration arm - 9 males, 3 females; 41~62years;2 liver, 2 kidney, 3 bone marrow, 5 heart transplant recipients, and 13 on FK506 coadministration arm - 7 males, 6 females;26~65years; 10 liver, 2 kidney, 1 heart transplant recipients). Blood CsA or FK506 concentrations before and after coadministration of voriconazole, and maximum concentration in one month from the first day of coadministration were monitored retrospectively. In most cases CsA or FK506 were administered as recommended doses regardless of coadministration of voriconazole, and blood concentration increased from 239.42±126. 77ng/ml to maximum 411.92±225. 76ng/ml in CsA coadministration arm(p=0.003), and from 7.72±2.79ng/ml to maximum 19.16±9.35ng/ml in FK506 coadministration arm(p=0.003). Gender, age, and the kind of transplant organ did not affect to the change of blood concentration in both two arms. In consequences, administration of voriconazole could affect on the blood CsA or FK506 concentration, and in cases of administra tion of voriconazole in transplant recipients treated with CsA or FK506, close monitoring and dose adjustment is needed.

유사시 데이터 복구가 가능한 암호 시스템에 관한 연구

채승철,이임영 순천향대학교 부설 산업기술연구소 1998 순천향 산업기술연구소논문집 Vol.4 No.2

One of the most important part in a cryptosystem is a key information. The key information and orignal message fundamentally keep the same value. If the key is damaged, it is able to cause all information to lose. Besides, another possible problem is that a dishonest internal user in a company could steal or destroy secret files by using a encryption system. In this paper, we proposed cyrptosystem that is able to offer key recovery in a emergency condition, and mechanism that is able to protect possible attack in the key recovery system.

요추간판 탈출증의 비수술적 치료효과에 관여하는 요인들

윤승호,방덕영 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

This study was undertaken to find out factors predicting the results of the nonoperative treatment for lumbar intervertebral disc. Inclusion criteria were as follows : 1) The patient was comfirmed lumbar intervertebral disc in the computed tomography and/or magnetic resonance imaging by a radiologist's reading. 2) The patient had undergone an intensive physical rehabilitation program for at least four weeks. 3) The patient should have no other medical problems which delayed the period of treatment or aggravated the symptom. 4) The patient should have no previous lumbar surgery. All patients were assessed by the low back pain protocol which was composed of symptom, clinical sign and activities of daily living scales before and after the treatment. Changes in LBP score were evaluated by age, sex, occupation, duration of the symptom, means of the payment, marital status, education period, radiologic finding, self assessement and MMPI. In conclusion, poor result could be predicted after the nonoperative treatment in the patient groups of : 1) duration of the symptom over 6 months, 2) hospital payment by others, and 3) high score in the Hypochondriasis and Hysteria scales in MMPI.

버스 운행시간 분석 및 최적 배차간격모형 개발

정영삼,고승영 명지대학교 대학원 1997 대학원논문집 Vol.1 No.-

The purpose of this study is, firstly, to analyze characteristics of travel times which are affected sensitively by changing traffic volumes, using explainable variables, such as the number of bus stops and total boardings, travel lengths, departure times of the day and days of the week. Secondly, this study is to develop a total cost model of the bus system which consists of operating cost of buses, travel time cost and waiting time cost of passengers and to obtain analytical solutions of optimal bus headways and numbers of operating buses which minimize the total cost. Also by using the data of bus travel time in Seoul, a case study for optimal headway planning as a function of days of the week and departure times of the day which minimizes the total cost was carried out.

내·외단열공법 및 온도조건별 냉동냉장창고 외피의 적정 단열계획

강승희,구보경,송승영 대한건축학회 2003 대한건축학회논문집 Vol.19 No.3

It is very important to apply the reasonable insulation method to refrigerated warehouse since temperature difference between storage and outside is so great. However, insulation method for refrigerated warehouse is not expressly provided in the Korean building code and there are few examinations for evaluation of each insulation method. Thus, this study aims to evaluate the economical efficiency of the refrigerated warehouse envelope with different insulation method(inside and outside insulation), temperature condition(0℃, -6℃ and -15℃) and insulation thickness(100㎜, 150㎜ and 200㎜ / 50㎜ or 250㎜). As results, it is proved to have the best economical efficiency when outside insulation method with thickness of 100㎜(0℃ and -6℃) and 150㎜ urethane(-15℃) is applied.