Mycobacterium mageritense에 의한 당뇨병성 족부 감염증 1예

김충종,김낙현,김문석,김계형,전재현,박문석,박경운,박완범,박상원,김홍빈,김남중,오명돈,최강원 대한감염학회 2008 감염과 화학요법 Vol.40 No.6

Diabetic foot infection is one of the important complications in patients with advanced diabetes mellitus. Limb threatening infections such as osteomyelitis, abscess, and necrotizing fasciitis are frequently accompanied by the disease. Non-tuberculous mycobacterium (NTM) is a rare causative organism of diabetic foot infection. Thus, if one is not suspicious or meticulous, infection due to NTM will be easily overlooked and this will result in delayed diagnose and treat. Therefore, it is necessary to consider NTM as the causative organism if the wound does not respond to the conventional antibiotic treatment and the culture from the adequately obtained specimen reveals atypical acid-fast bacilli. We present a case of diabetic foot infection with osteomyelitis and abscess due to Mycobacterium mageritense, one of the rapid growing mycobacteria, that was successfully treated with surgical debridement and appropriate antibiotic treatment.

수치지형모형에 의한 도시계획 지구의 정지표고 산정에 관한 연구

박운용,차성렬,신상철 동아대학교 공과대학 부설 한국자원개발연구소 1994 硏究報告 Vol.18 No.1

The use of digital terrain model has been enlarged in calculation of earthwork plays a major rule in plan or design of many civil engineering projects, and thus it has become very important to advance the accuracy of earthwork calculation. The earthwork volume,an important factor in the field of civil engineering,could be counted with the computerized by the use of simpson's 1/3 and 3/8 rules. The thesis is the earthwork volume could be counted by the measurement of HAEUN-DAE-GU topograph data.

組織의 核心價値測定을 위한 韓國人의 價値特性 把握

朴運盛,朴昇瞳 慶北大學校 經濟經營硏究所 1994 經商論集 Vol.22 No.1

염분적응에 따른 뱀장어 표피의 미세 구조적 변화 : Ⅰ. 상피세포 Ⅰ. Epithelial Cell

박인식,김진정,조운복,박상옥 부산대학교 유전공학연구소 1995 분자생물학 연구보 Vol.11 No.-

뱀장어, Anguilla japonica의 표피를 구성하는 주종 세포인 상피세포는 80Å 정도의 많은 당김세사를 함유하고 있어서 표피의 골격 유지에 중요한 역할을 하고 있다. 회유행동 측성에 의해, 성숙된 뱀장어는 바다로 나가게 되고 표피는 급격한 환경변화를 겪게 되는데 그 현상들을 살펴보면 먼저 상해반응으로 세포 내의 과립 형질내세망의 내강이 확장되는 현상과 다양한 크기의 공포의 증가로 인해 상피세포들 사이의 공간이 확장되며 일부 세포에서는 괴사 또는 변성되는 형태인 다층층판구조를 갖기도 한다. 이에 대한 능동적 대퍼로 부착반쪽으로 모이는 당김세사들이 일정한 방향성을 갖게 되며, 상피세포 사이의 연접부위에 부착반의 수가 증가되며, 미토콘드리아, 형질내세망 등 세포소기관이 발달되고, 분비과립의 증가 등 분비양상이 증가되고, 능동적인 염배출과 연관된 핵상부의 중앙축을 따라 미토콘드리아 및 과립 형질내세망이 풍부한 세포도 나타났다. 이와 같은 변화는 염분농도의 증가에 따른 환경적요인에 의해 일어나는 상피세포의 기능적 방어기작이라고 사료된다. The epidermis of the Korean eel, Anguilla japonicus, was examined for the study of structural and funcional adaptation mechanism by change in external environment during the migration from fresh water to sea water. The epithelial cell which was observed in the eel epidermis is characterized by the presence of numerous cytoplasmic tonofilaments that attributes to the epithelial structures. Many structural changes were occured in the epithelial cell according to adaptation of high concentration of salt solution. First, Structural lesions were observed. The lumen of rough endoplasmic reticulum was dilated and myelin figures which was suspected to necrosis or denaturation were noted. Extensive cytoplasmic vacuolations were appeared, which caused increase of the intercellular space. Second, active responsive mechanism against the structural lesions in high salinity were observed. Cytoplasmic tonofilaments which attached to desmosome have orientation from central to peripheral region and then aggregrated each other. And number of desmosomes was increased between the cells. The cell organelles which contained mitochondria, small vesicles, et al. were more developed and number and amount of secretory granules were increased than fresh water adapted eel epithelial cell. Mitochondria- and rough endoplasmic reticulum-rich cells which related to active salt secretion were appeared.

직무만족 및 직무성과에 대한 기업문화특성의 영향

박운성,박승동 慶北大學校 1997 經商論集 Vol.25 No.1

컴퓨터 매핑시스템에 의한 국토정보관리 기본구상에 관한 연구

박운용,차성렬,신상렬 東亞大學校 大學院 1994 大學院論文集 Vol.19 No.-

Computer Mapping System(CMS) are being used in various government offices as well as coporates as a tool in decision making. Efforts are being made to implement computer mapping system databases to systematically and effectively carry out planning, management and monitoring in various fields. But the present dituation is that the database design itself is a big job since the methodology of planning and design of mapping systems are still being studied. This study is about the base conception of Land Information Management, which is an important and time consuming activity necessary in the implementation of such systems. The study was then applied to highway, environment, map management where the functions and data used in highway, environment, map management system were identified through system analysis and the computer mapping system database was designed based on this analysis. Also appplication systems were developed to support departments which used various maps and drawings. Conclusively, the techniques introduced in this study could serve as a useful tool not only in buiding more specific land evaluation system but also in collecting data necessary for Land Information Management System.

다중 중합효소 연쇄반응을 이용한 반코마이신 내성 장구균의 신속 검출

박성언,박수진,엄용빈,김종배,송혜원,박상욱,김양수,김근희 THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 1999 Journal of biomedical laboratory sciences Vol.5 No.1

일반적으로 임상검사실에서 vancomycin resistant enterococci(VRE)를 검출하는 일은 어렵고, 시간이 많이 들며, 검체처리 비용도 많이 든다. 따라서 본 실험은 임상검체에서 분리된 세균으로부터 VRE를 신속하게 확인하고, 진단하기 위한 방법으로서 다중 중합효소 연쇄반응을 확립하였다. 본 실험에 사용된 primer는 장구균에 특이한 유전자인 vanA, vanB, vanC-1, vanC-2/3각각의 염기서열을 기초로 primer를 제작하고, 다중 중합효소 연쇄반응을 실시하여 임상검체로부터 분리된 VRE 유전자의 type 및 분포율을 조사하고자 하였다. 국내에서 분리된 75주의 장구균을 대상으로 다중 중합효소 연쇄반응을 실시한 결과 36주의 분리균주에서 vancomycin에 대해 높은 저항성을 보이는 vanA 유전자를 가진 것으로 나타났다. 그리고 18주에서는 vancomycin에 낮은 저항성을 내성을 보이는 vanC-1또는 vanC-2/3유전자를 보유한 것으로 나타났다. 따라서 본 실험에서 확립한 다중 중합효소 연쇄반응 기법은 신속한 VRE 진단 방법으로 이용할 수 있을 것이다. It is generally difficult, time-consuming, and expensive for the clinical laboratory to detect vancomycin resistant enterococci (VRE). The aim of this study was to develop and evaluate the multiplex polymerase chain reaction (PCR) assay system as a diagnostic tool for the rapid detection of VRE from clinical samples and/or for the identification of VRE from the bacterial strains isolated from clinical specimens. Specific primers, designed from the nucleotide sequences respectively encoding the vanA, vanB, vanC-1, vanC-2/3 genes in enterococci, were coupled in a multiplex PCR assay system. With this multiplex PCR assay system, we investigated the incidence rates and types of VRE isolated from clinical samples. A total of 75 strains of enterococci were isolated in 3 general hospitals in Korea. Of these isolates, 36 strains showed a pattern of highlevel vancomycin resistance which associated with vanA gene, whereas 18 strains showed lowlevel vancomycin resistance associated with vanC-1 or vanC-2/3 gene. Thus, multiplex PCR assay method established in this study could be applied for the rapid detection of VRE.

組織文化의 接近法과 比較

朴運盛 경북대학교 경제경영연구소 1988 經商論集 Vol.16 No.-

The theory of all organizations most of which are consisted of human elements has developed many theories through the research of effective integrating processes of human elements. Through the debats whether organizations can be seen as a means or ends, new understanding of organization, that is, an understanding of organizations by cultural metaphor that is really worth a place of life where most people spend most of their time, is needed. That is the aim of this paper is build a healthy organizational culture. When the organization is to fulfill the basic on-going organizational factors of survival, security, and growth with achieving its own goals, it must face its environmental change actively and solve the issues of the organization dynamically. this means that all the members of organizations should have the income-raising force as Leibenstein asserted where the ethos of all the nembers are strong and positive. For the building of a healthy organizational culture, the behavior change must be done with the change of the change of the members' value and beliefs. Although the change of values and beliefs must be done in attaibute to the internal change of each member, this is not so easy one. Thus for the building of healthy of strong organizational culture, we ca assume about seven methods with the external and internal way of change in the each member's value and belief system. The seven methods are as below: 1. Change the conscious structures of members of members in the direction of value oriented. 2. Seduce to change of the values of members through the behavior modifications with the use of rituals. 3. For the change of members' behavior, one must dispatch the organizational heroes to the core positions of organization and let the employes assimilate themselves to the heroes whose actions are value-oriented. 4. Make the organizational climate open to each other through lubricative communications. 5. Cut the organizational hierarchy short to make top and down intimate and the process of decision making dynamic. 6. Make to face with active to the environmental change by the development of creativity in the positive environmental adaptiveness. 7. Make the desirable counter culture vital and make it a dominant culture in the organization. The most important problem in these processes is the ethics of methods to change individual value. It should not make the people their values with another. To make the people accept the ultimate goal of organization, rationally acceptable values should be shown to the individuals. That is just the superodinate goals. Then the organization must show off the people that the organization is trying to actualize this superordinate goal with them. Today is the high time that management philosophy dominates the organizational life and determines whether it can sustain the organizational culture healthy of not which is the pivot of organizational life.

농촌지역 폐교의 노인복지시설 및 주민 커뮤니티센터 활용에 관한 연구 : 거주자의 생활패턴과 지역시설 이용실태를 중심으로 Life Pattern and Use of Facilities of Rural Residents

박경옥,조현주,이상운 대한건축학회 2004 대한건축학회논문집 Vol.20 No.1

Closed schools in rural areas are hardly used for the residents. The purpose of this study is to suggest the possibility to use these facilities for elderly welfare spaces or community centers of residents. For this purpose this article studied life pattern and use of facilities of rural residents. Interviews on the use of leisure time, additional jobs other than agriculture and the use of facilities were conducted on 91 residents living in the educational area of 2 preliminary schools which were just closed. The 2 schools-Seongdae branch school of Baekgok preliminary school and Ohsang branch school of Gujeong preliminary school- are located in Jincheon-gun, Chuncheongbuk-do. Rural residents have relatively much spare time more than 6 hours a day, but their leisure activities are very restrictive in diversity. Economic burden, lack of time in their agricultural period and inconvenient traffic ask closed schools near and familiar to the residents to be converted to the compound community center with diverse functions and leisure programs. It would improve the life quality of agricultural residents and lessen their economic burden.

震顫을 主 症狀으로 入院한 患者 30例에 對한 臨床的 考察

朴智雲,李相龍 대전대학교 한의학연구소 2001 혜화의학회지 Vol.10 No.1

The clinical study was carried out the 30 patients with tremor who were treated in Daejeon University Oriental Hospital from 1 April 1997 to 31 March 2001. The results were summarized as follows. 1. The ratio of female was higher, especially in the psychosomatic tremor, the ratio of female was higher and in the age distribution the aged over 50 were higher frequence. 2. The case without past history was most, the most ordinary preceding disease was hypertintion and the next was diaetes, dringking history had no concern with tremor, first visit was msot, in the psychosomatic tremor complicaiton by relation was the most inducing factor and both parkinson tremor and essential tremor were no inducing factor. 3. Tremor appeared to be busy in extremities, parkinson tremor appeared to be accompanied with musculoskeletal system symptoms and they were in descending order lower limb weakness, extremities numbness, general body weakness e.t.c. both essential trmor and psychosomatic tremor appeared to be accompanied with psychosomatic symptoms and they were in descending order dizziness, headache e.t.c. 4. In classification of Four Human coporeal constitution the number of patients, Tae-Eum-In(太陰人) was most, the prescription drugs of tranquillizing the liver and relieving anxiety such as GYEJIYONGGOLMORYETANG(桂枝加龍骨牡蠣湯) and nourishing Yin, blood and relieving anxiety such as SAMULANSINTANG(四物安神湯) were used to be busy. 5. The rate of treatment was collectively improved and was higher in the yaung age than in the old age, the period of the clinical history was the shorter within on e month, the rate of improvement was the better