食用油脂類에 對한 免疫生物學的 硏究

朴炳哲,文宰奎,朴榮吉,金杏順,安年衡,金度勳,金正勳,安榮根,李相根,鮮于演 圓光大學校 1990 論文集 Vol.24 No.2

食用油脂는 健康維持에 必須的인 營養素이다. 그러나 食用油脂는 脂肪을 構成하는 脂肪酸의 種類와 攝取하는 量에 따라 健康을 保衛하는 必須的인 食品의 成分이 되기도 하고 有害한 影響을 끼칠 수도 있어서 脂質代謝와 關連된 疾病 뿐만아니라 老化를 促進하고, 乳房癌, 大腸癌等의 癌發生과도 關連된 것으로 밝혀져 있다. 本 硏究는 우리生活環境에서 食用으로 接할 수 있는 10種의 油脂에 對한 免疫生物學的인 活性에서 究明한 結果 對照群인 참기름食餌群에 比해 올리브유食用群은 全般的으로 體液性 및 細胞性免疫을 有意性있게 增加시켰으나, 大食細胞의 活性과 末梢循環白血球數는 有意性없는 減少를 보였고, 動物性 油脂인 牛脂食餌群과 植物性 油脂인 옥수수기름食餌群, 들기름食餌群, 米糠油食餌群, 大豆油食餌群, 菜種油食餌群 및 고추씨기름食餌群에서는 全般的으로 體液性 및 細胞性免疫, 大食細胞의 活性 및 末梢循環白血球數를 有意性있게 減少시켰다. This study was performed to investigate the effects of edible oils and fats on the immunobiological responses in ICR male mice. Ten groups of experimental diets, such as sesame oil diet, beef tallow diet, lard oil diet, olive oil diet, corn oil diet, perilla oil diet, rice polishing oil diet, soybeen oil diet, rape seed oil diet, and red pepper seed oil diet were fed adlibitum to the ICR male mice for 27 days. The results of this study were summarized as followings. 1. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes in sesame oil group were increased. However, the increasing rate of body weight and the weight retios of spleen and thymus to body were generally decreased. 2. Hemagglutination titer(HA) and rosette forming cell(RFC) of the beef tallow group and the lard group were significantly lower than the sesame oil group(P<0.01), but the lard group significantly increased Arthus reaction and delayed type hypersensitivity(DTH)(P<0.01). 3. Arthus reaction, DTH, and RFC of the olive oil group were significantly higher than the sesame oil group(P<0.01). 4. DTH of the corn oil group was significantly higher than the sesame oil group(P<0.01) whereas phagochyte activity was significantly lower(P<0.01). But no statistically significant differences were found between the two groups in the humoral immune response. 5. HA, PFC, DTH, RFC, phagocyte activity, and number of leukocytes of the perilla oil group and the rice polishing oil group were significantly lower than the sesame oil group(P<0.01). 6. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes of the soybeen oil group, the rape seed oil group, and the red pepper oil group were significantly lower than the sesame oil group(P<0.01).

내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

A Set of Roughness Corrected Charts for the Capillary Tube Design for R-22 System

Chang-Nyeon Kim,Eui-Pil Hwang,Young-Moo Park 대한설비공학회 1996 International Journal Of Air-Conditioning and Refr Vol.4 No.-

A new set of capillary tube design charts is proposed. Roughness effects on the mass flow rate are taken into account. A steady state, one-dimensional, adiabatic model is numerically simulated. Numerical results are verified by experiments. Mass flow rates are measured at 142 different conditions. Calculated mass flow rates agree with measured values within 10%.<br/> Based on this study a new set of simple equations for the mass flow rate of capillary tube is defined and a new set of capillary tube design charts is proposed. This set consists of three charts:the first is for the mass flow rate of the standard capillary tube(d_(standard)=1.6㎜, Lstandard=2.030㎜, ε_(standard)=2.5㎛), the second for the flow factor(Φ₁) and the third for the roughness factor(Φ₂). The new set of equations for the mass flow rate is proposed as follows:<br/> m = Φ₁ Φ₂ m_(standard)<br/> Φ₁ = m(L, d, ε_(standard)) / m_(standard)(Lstandard d_(standard) ε_(standard))<br/> Φ₂ = m(Lstandard d_(standard) ε) / m_(standard)(Lstandard d_(standard) ε_(standard))<br/> Calculated results from the charts are in agreements with those from experiments within 4.5%~9.6%. The sets of charts are in very good agreements with the computer model within 3%.

An Experimental Investigation of Thermodynamic Performance of R-22 Alternative Blends

Chang-Nyeon Kim,Young-Moo Park 대한설비공학회 1998 International Journal Of Air-Conditioning and Refr Vol.6 No.-

R-410a and R-407c which have the best potential among R-22 alternatives were tested as drop-in refrigerants against a set of R-22 baseline tests. The performance evaluations were carried out in a psychrometric calorimeter test facility using the residential spilt type air conditioner under the ARI rating conditions. Except the lubricant and hand-operated expansion valve, the other parts of the air conditioner were the same with the commercial system. Performance characteristics were measured; compressor power, capacity, VCR, mass flow rate and COP. The tests showed that R-407c can be directly charged into the current refrigeration system because its vapor pressure and other thermophysical properties are similar to those of R-22. However, it is required to change the volume flow rate of compressor in order to achieve the volumetric capacity of R-22. This results from its relatively small VCR and capacity. Meanwhile, R-410a has vapor pressure values too high to be substituted for the current system and this resulted relatively low COP of R-410a compared to that of R-22.

Incidence and risk factors of lower extremity lymphedema after gynecologic surgery In ova nan cancer

( Eun Young Ki ),( Jong Sup Park ),( Keun Ho Lee ),( Seok Nyeon Bae ),( Soo Young Hur ) 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-

Drop - In Evaluation of Thermodynamic Performance of R-22 Alternative Refrigerant Mixtures

Chang-Nyeon Kim,Young-Moo Park 대한설비공학회 1997 International Journal Of Air-Conditioning and Refr Vol.5 No.-

Thermodynamic performance of eight zeotropic R-22 alternative refrigerant mixtures selected by AREP(R-22 Alternative Refrigerants Evaluation Program) and R-32/R-125/R-134a (23%/25%/52%), namely R-407C, were evaluated by the “drop-in" simulation.<br/> An existing air conditioner was selected and its design data were used for the simulation under the “ARI Test A" air conditions. The degree of vapor superheat at the compressor inlet is fixed at 5℃ for all the mixtures. The results of the simulation were compared with those of R-22.<br/> COPs of all mixtures, except for R-32/R-227ea(35%/65%) and R-32/R-125/R-134a (10%/70%/20%), were higher than that of R-22 by 2%~8%, while the capacities were lower than that of R-22 by 13%~27%.<br/> COP of R-32/R-134a(40%/60%) was 2.4% higher but the capacity was 15% lower than those of R-22. In the case of R-32/R-134a(30%/70%), COP and capacity were 5.5% higher and 15% lower than those of R-22, respectively.<br/> Among the ternary mixtures, R-407C and R-32/R-125/R-134a(30%/10%/60%) showed the best performances. COP of R-407C was 2.7% higher than that of R-22 but the capacity was 19% lower.

동해 울릉분지 서측 대륙붕 퇴적분지 탄성파 층서 및 구조 발달 연구

강년건(Nyeon-Keon Kang),박용준(Young-Joon Park),유동근(Dong-Geun Yoo) 대한지질학회 2019 대한지질학회 학술대회 Vol.2019 No.10

가토에서 Heparin 투여는 뇌 공기색전증으로 인한 신경학적 손상을 감소 시키는가?

홍영호,김창성,김은성,박철주,유건희,이윤기,김성년,최종호 대한마취과학회 1997 Korean Journal of Anesthesiology Vol.33 No.4

Background : Neurological injury after cerebral air embolism may be due to thromboinflammatory responses at sites of air-injured endothelium. Because heparin inhibits multiple thromboinflammatory processes. we hypothesized that heparin would decrease neurological impairment after cerebral air embolism. Methods : Anesthetized rabbits received either heparin (n=14) or saline(n=13), 5 minutes before air injection (150 μL/kg). Heparin was given as a 200 IU/kg bolus and followed by a constant infusion of 75 IU/kg/h for 2 hours. Equal volumes of salines were given to saline group. Two hours later, anesthesia was discontinued. Rabbits were neurologically evaluated 24 hours after air embolism. Results : Heparin group had significantly less neurological impairment at 24 hours (34 14) than saline controls(52 8) (p=0.0013). Conclusions : When given prophylactically, heparin decreases neurological impairment caused by severe cerebral arterial air embolism. (Korean J Anesthesiol 1997; 33: 604∼609)

Effects of the precipitation of secondary phases on the erosion-corrosion of 25% Cr duplex stainless steel

Kim, Young-Jae,Kim, Su-Won,Kim, Han-Byeol,Park, Choong-Nyeon,Choi, Yun-Il,Park, Chan-Jin Elsevier 2019 Corrosion science Vol.152 No.-

<P><B>Abstract</B></P> <P>This study examined the effect of aging at 850 °C on the precipitation of secondary phases and the resultant erosion-corrosion behavior of 25% Cr duplex stainless steels (DSS). An aging time of 30 min, which led to a ratio of reactivation current to activation current (<I>i<SUB>r</SUB>/i<SUB>a</SUB> </I> × 100) of ˜1% in a DL-EPR test and a current density of ˜0.8 mA cm<SUP>−2</SUP> at 9 m s<SUP>−1</SUP> in a jet impingement test, is regarded as a boundary aging condition for erosion-corrosion. Further, the current density response of ˜0.8 mA cm<SUP>−2</SUP> can be considered a criterion for the surface depassivation resulting from erosion-corrosion.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The effects of aging at 850 °C on the precipitation of secondary phases and the erosion-corrosion behavior of 25% Cr duplex stainless steel were studied. </LI> <LI> An aging time of 30 min is regarded as a boundary aging condition for erosion-corrosion. </LI> <LI> A current density response of ˜0.8 mA cm<SUP>−2</SUP> is considered to be a criterion for surface depassivation after the initial erosion-corrosion. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

물리치료학과 학생들의 임상실습 만족도

김광년(Kwang-nyeon Kim),강승리(Seung-ri Kang),김영욱(Young-wook Kim),남궁민(Goong-min Nam),박소영(So-young Park),유태관(Tae-gwan Yoo),장정규(Jung-gyu Jang),강순희(Soon-hee Kang) 한국정보통신학회 2022 한국정보통신학회 종합학술대회 논문집 Vol.26 No.1

이 연구의 목적은 전국의 4년제 물리치료학과 학생들의 임상실습 만족도를 조사하는 것이었다. 연구대상자들은 총 157명의 대학생들로 구성되었다. 대상자들은 임상실습만족도 설문지 36문항과 일반적인 특성을 묻는 5개 문항으로 구성된 온라인 설문조사를 완성하였다. 수집된 데이터는 빈도분석, 독립 t 검정, 일원배치분산분석 및 사후검정(Schffe)을 사용하여 분석되었다. 연구결과는 다음과 같다. 학생들의 임상실습 만족도는 평균 3.84점(5점 만점)이었다. 학생들의 만족도는 ‘임상실습 후 만족감’의 항목에서 가장 점수가 높았고 임상실습에서 ‘내적 갈등’과 ‘임상실습 평가’에서 가장 점수가 낮았다. 학생들의 임상실습 만족도는 전공 만족도에 따라 유의한 차이가 있었다. 즉, 전공 만족도가 높을수록 임상실습 만족도가 더 높았다. 임상실습 만족도는 성별, 학년, 실습기간 및 실습기간에 따라 유의한 차이가 없었다. The purpose of this study was to investigate the satisfaction of clinical practice for university students in the physical therapy department. 163 students participated in the study. The subjects completed an online survey that consisted of 36 clinical practice satisfaction question and 5 questions of general characteristics. The collected data was analyzed by using frequency analysis, independent t-test, one-way ANOVA and Scheffe post hoc analyses with a significant level of 0.05. The students’ satisfaction of clinical practice was 3.84 in average on a scale of 5. The students’ satisfaction was the highest for the item ‘Satisfaction after clinical practice’, and the lowest for the item ‘Internal conflict in clinical practice’ and ‘Evaluation of clinical practice’. The students’ satisfaction of clinical practice showed significant differences according to the satisfaction of the major (p<.001), however, no significant difference according to gender, grade, training period and practice institution.