Endoscopy and Imaging Modalities/Basic Science of Gastrointestinal Disorders/Miscellaneous : Changing Pattern Of Digestive And Liver Disease In Korea, 1990-2006 Year; A Single Center Study

( Jung Hyun Kwon ),( Sang Woo Kim ),( In Sik Chung ),( Myung Gyu Choi ),( Kwan Woo Nam ),( Jung Pil Suh ),( Jae Hyuck Chang ),( Won Haing Hur ),( Yu Kyung Cho ),( Jae Myung Park ),( In Seok Lee ) 대한소화기학회 2007 SIDDS Vol.9 No.-

Background/Aims: Westernization in many Asian countries have changed lifestyles and diets, so once rare diseases have now become prevalent. The aim of this study is to investigate the changing pattern of digestive and liver disease in Korea, from 1990 to 2006. Methods: We extracted data specific gastrointestina (GI) disease based on the International Classification of Diseases code from the in-patients records at the Kangnam St. Mary`s Hospital in 1990, 1996 and 2006. This hospital is a tertiary-care hospital in Seoul, Korea, which has a capacity of 800 beds. Results: The admission rate for GI disease increased between 1990 and 2006. Overall in-patients were 1,623 persons in 1990, 2,368 persons in 1996 and 4,166 persons in 2006. The mean age of in-patients increased as time went by. A stomach cancer was the most common diagnosis during all periods, but its prevalence has decreased. Colon cancer ranked the 7th in 1990, but markedly increased and now ranks the second. The third was a hepatocellular carcinoma. The bile duct and gallbladder cancer, pancreas and esophageal cancer ranking followed with little interval change. In cases of cancer patients, a regular admission dramatically increased for chemotherapy. The number of patients admitted with pre-malignant neoplasm of stomach and colon increased remarkably with the development of endoscopy. The liver transplant, inflammatory bowel discase, and reflux esophagitis emerged form mid-1990s with greater frequencies, yet much below the levels found in the West. The admission rate for peptic ulcer, especially ulcer bleeding remained relatively stable, despite a decreased rate for ulcer perforation. Liver cirrhosis, hepatitis, cholelithiasis with cholecystitis-cholangitis, appendicitis, hemorrhoid and gastritis all decreased. Conclusions: The stomach cancer is the leading cause of admission, despite a recent decline. Colon cancer showed a marked rise. The liver transplant, inflammatory bowel disease and reflux esophagitis were new diagnosis with an increased tendency.

不等式의 解法에 關한 小考

南圭昌 진주산업대학교 1969 論文集 Vol.3 No.-

The solution of inequality is in understanding the basic elements and its relations, and it is more effective to utilize signs an graphs in arrangement of the answer.

數學科 學習指導法의 考察

南圭昌 진주산업대학교 1968 論文集 Vol.2 No.-

Today with the keen development of science the basic subject of mathematics is advancing quickly too so that effective guidance is necessary. Accordingly for effective guidance in mathematics practice, purpose, content and basic principles must be established and after the examination of an adequate text guidance must be given with various techniques. Accordingly it will be more effective and give more efficient practive if, among the exixting forms which are able to guide with emphasis on the student, teacher, a combination of both, simple test methods, the most effective method is employed, namely, with the teacher central to develop the practice in accordance with the purpose. To achieve this, guidance must be that which involves text research and enthusiasm which does not avoid the focus on practice.

專門大學 電子通信 技術人力을 위한 産學協同敎育方案 硏究

金圭煥,高南泳,梁義藏 군산대학교 1987 群山水産專門大學 硏究報告 Vol.21 No.1

In modern industry, the reorganizations of organization and job classification of telecommunication are required for the Advanced Information Society (AIS) which is being accomplished by the entrance of new media, Information Service Noetwork plan for Korean government offices (ISN) and Integrated Services Digital Network (ISDN). Accordingly, the demand of competent technician would be increased for performance of the related job. In this paper, educational system of College-Industry-Korea Vocational Training and Management Agency Cooperation for the telecommunication department was studied for the effective education of the specified technician to be engaged in the specified job. The results were as follows. 1. By the establishment of College-Industry-Korean Voctional Training and Management Agency and their linking operation, the gap in their technical level could be narrowed. In addition, the effective improvement for the field practice, the official approval system, the normalization of the special education and the settlement of its related cooperation business with administrative agencies could be advanced promptly. 2. The industry should take the advancement of its technical level by establishing of employ job for the professional course technician of junior college graduates and by hiring of the 2nd class licensed technician for the related job. 3. Telecommunication department should carried out not only the efficient operation of curriculum (Table 13.) and development of teaching materials fur special technical education according to each course , but also the substantiality of field practice. 4. Korea Vocational Training and Management Agency is desired to develope the problems of examination approached to practical technique level of industry and to improve the applicant qualification, examination date and method of practical examination for normalization of technical education in junior college telecommunication department.

2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36 to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65 years or more of age were classified into group I to VI, respectively. A total of 107,467 visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009) was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

기존 공동주택의 실내공기질 실태에 관한 측정 연구

이윤규,김창남 대한건축학회 2004 대한건축학회논문집 Vol.20 No.11

Because of the airtightness of buildings or the misuse of building materials, indoor air pollution has been increasingly concerned. Especially, SHS(Sick House Syndrome) and MCS(Multi Chemical Sensitivity) which can have bad influences on the resident in an existing apartment house as well as newly constructed apartment house start to attract public attention. Also, Indoor air quality of existing apartment house is poor compared with other country's standards. In this study, to investigate the actual condition of indoor air quality in domestic apartment house, we measured the indoor air pollutant of existing apartment house that pass one or two years since constructed. In formaldehyde case, 50% of total investigation object (average 0.110, max, 0.311 ㎎/㎥), and in TVOC(Total Volatile Organic Compound) case, 72.2% of total existing apartment house(average 0.630, max, 1.198 ㎎/㎥) were excess both WHO and Japan Ministry of Health. Labour and Welfare's guidelines. In each VOCs, indoor concentrations of Toluene, Xylene and Ethylbenzene. Styrene were very high. Indoor concentrations of benzene, trimethylbenzene and tetrachloethylene were quitely high.

枾根이 PE로 유발된 家兎의 수축혈관에 미치는 영향

김희철,남창규 世明대학교 한의학연구소 2002 韓醫學硏究所 論文集 Vol.4 No.-

This study was undertaken to define the effect of Diospyros Kaki L. Radix on the phenylephrine-induced arterial contraction and the mechanism of Diospyros Kaki L. Radix-induced relaxation. In order to investigate the effect of Diospyros kaki L. Radix on contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of Diospyros kaki L. Radix induced relaxation, Diospyros kaki L. Radix extract infused into contracted arterial strips induced by phenylephrine after treatment of indomethacin, N_(t) nitro-_L-arginine, or tetraethylammonium chloride, and Ca^++ infused into contracted arterial strips by phentlephrineafter treatment of Diospyros kaki L. Radix in a CA^++ free solution. Diospyros kaki L. Radix relax arterial strip with or without endothelium contracted by phenylephrine, but in the strips without endothelium, Diospyros kaki L. Radix-induced relaxation was significantly inhibited. The endothelium-dspendent relaxtion induced by Diospyros kaki L. Radix was decreased by the pretreatment of N_(t) nitro-_L-arginine, but it was not observed in the strips pretreated with indomethacin or tetraethylammonium chloride. When Ca^++ was applicated the strips which were contracted by phenylephrine in a Ca^++ free solution, arterial contraction was increased. But pretreatment of Diospyros kaki L. Radix inhibited contractile response to Ca^++. We suggest that Diospyros kaki L. Radix may directly suppress influx of extra-cellular Ca^++ and indirectly suppress influx of extra-cellular Ca^++ though the formation of nitric oxide in the vascular endothelial cells.

刺人參이 PE로 유발된 토끼의 수축혈관에 미치는 영향

권오율,남창규 世明대학교 한의학연구소 2002 韓醫學硏究所 論文集 Vol.4 No.-

This study was undertaken to define the effect of Oplopanacis Cortex on the phenylephrine-induced arterial contraction and the mechanism of Oplopanacis Cortex-induced relaxation. In order to investigate the effect of Oplopanacis Cortex on contracted rabbit carotid arterial strips, transverse strips with intact or damaged endothelium were used for the experiment using organ bath. To analyze the mechanism of Oplopanacis Cortex-induced relaxation, Oplopanacis Cortex extract infused into contracted arterial strips induced by phenylephrine after treatment of indomethacin, tetraethylammonium chloride or N_(t) nitro-_L-arginine. The relaxation of Oplopanacis Cortex was dependent on the presence of endothelium, showing that Oplopanacis Cortex-indeced relaxation was not observed in the strips damaged endothelium. The endothelium-dependent relaxation induced by Oplopanacis Cortex was suppressed by the pretreatment of N_(t) nitro-_L-arginine, but it was not observed in the strips pretreated or tetraethylammonium chloride. These result demonstrated that Oplopanacis Cortex may inhibit phenylephrine-induced constraction through the production of nitric oxide in the vascular endothelial cells.

1996-1997년 겨울철에 유행한 인플루엔자의 임상역학적 분석 및 원인 바이러스의 분리

김수정,정규영,이용화,기창석,이남용,이상일,김지희 대한감염학회 1997 감염 Vol.29 No.4

목적: 인플루엔자는 매년 겨울 전 세계적인 유행을 일으키는 급성 호흡기 질환으로 높은 이환률과 사망율을 보인다. 국내에서도 1996-1997년 겨울철에 다수의 보고가 있었으나 아직 체계적인 감시가 이루어지고 있지 못하다. 저자들은 이 기간 동안 인플루엔자 바이러스 감염의 역학적 특성과 임상상을 연구하여 인플루엔자 감시의 기초 자료를 제공하고자 하였다. 방법: 1996년 10월부터 1997년 4월까지 삼성서울병원 임상병리과에 인플루엔자 바이러스 배양 검사가 의뢰된 모든 검체를 대상으로 인플루엔자 바이러스의 분리율과 유행 양상, 그리고 환자들의 임상상을 후향적으로 조사, 분석하였다. 결과: 총 461명의 환자로부터 525례의 검체가 의뢰되어 총 98명의 환자로부터 인플루엔자 바이러스가 분리되었다. 인플루엔자 A형은 54명의 소아 환자와 4명의 소아 환자로부터 분리되었다. 아형과 항원 특성 검사를 시행한 31례의 인플루엔자 A형 중 한 예에서 A/Wuhan/359/95 유사주로 확인되었고 12례의 인플루엔자 B형 중 5례에서 B/Guangdong/8/97 유사주로 확인되었다. 인플루엔자의 유행 양상은 3월과 4월 중순, 두 번의 인플루엔자 최고 분리 시점이 관찰되었고, 가장 많은 불리 빈도를 보인 연령층은 인플루엔자 A형의 경우 1세 미만이었고 인플루엔자 B형의 경우 3-5세였으며 폐렴이 가장 흔한 호흡기 질환이었다. 결론: 저자들은 3차 의료기관에서 분리된 인플루엔자 바이러스에 대한 역학적, 임상적 특성을 연구하였다. 지역사회에 대한 광범위한 연구가 아니므로 국내의 전반적 상황과는 차이가 있을 것으로 생각되지만 우리나라에서도 인플루엔자 바이러스의 이환률이 낮지 않을 것으로 생각되며, 보다 조직적이고 전국적인 인플루엔자 감시가 이루어져야 할 것으로 사료된다. Background: Although influenza has been a leading cause of global morbidity and mortality, we have few data regarding the epidemioloical and clinical characteristics of influenza activity in korea. Since an outbreak of influenza was recognized during winter of 1996-1997, we analysed the epidemiological and clinical features of influenza activity in the hospital seeting. Methods: All clinical specimens requested for isolation of influenza virus at Samsung Medical Center from October 1996 to April 1997 were included. Mardin-Darby canine kidney (MDCK) cell line was used for virus culture. Isolated viruses were confirmed with immunostain followed by subtyping. The demograpic and clinical characteristics of the patients were reviewed retrospectively. Results: Ninety eight influenza viruses were isolatd from 461 patients (21.3%). Influenza A and B virus were isolated from 58 (54 children and 4 adults) and 40 pediatric patients, respectively. One of 31 influenza A viruses was confirmed as A/Wuhan/359/95-like strain and 5 of 12 influenza B viruses were confiremd as B/Guangdong/8/97-like strains. Two distinctive peaks of influenza activity were recognized and the most common age of patients was less than 1 year for influenza A, and 3 to 5 years for influenza B. Common lower respiratory infections were pneumonia followed by croup, bronchiolitis and laryngitis. Conclusion: We analyzed the epidemiological and clinical features of influenza activity during winter of 1996-1997. Although this study was performed not in the community but in the hospital setting, the morbidity caused by influenza may not be low in Korea. Therefore, nationwide surveillance for influenza activity is warranted.

원발성 두개강내종양 2,616례의 통계학적 연구(1976-1995)

황승균,정희원,오창완,양희진,남도현,이상형,정영섭,김동규,왕규창,한대희,최길수,조병규 대한신경외과학회 1997 Journal of Korean neurosurgical society Vol.26 No.7