우리나라 임신부에서 대유행 인플루엔자(H1N1) 2009 감염

김백남,문치숙,곽이경,김연숙,이꽃실,이창섭,허지안,김의석 대한감염학회 2011 Infection and Chemotherapy Vol.43 No.1

Background: Pregnant women are at an increased risk for severe illness and complications associated with pandemic (H1N1) 2009. This study was conducted to identify the severity of pandemic (H1N1) 2009 in pregnant Korean women. Materials and Methods: The demographic and clinical data from pregnant women with laboratory confirmed pandemic (H1N1) 2009 during September to December 2009 were retrospectively collected from 8 hospitals in Korea. Results: A total of 150 pregnant women with pandemic (H1N1) 2009 were identified. The median age was 30 years (range: 22-39 years), and the median gestational age (n=114) was 20 weeks (range: 1-39 weeks). All but one patient with secondary bacterial pneumonia had influenza without complication. Although 12 pregnant women needed hospitalization, there were no patients who needed admission to the intensive care unit or who died. Only one hospitalized patient had elective cesarean section because of oligohydamnios. No maternal or fetal complications directly related to the pandemic (H1N1) 2009 were identified among the 67 pregnant women who were followed up for 1 to 185 days after their influenza illness, including 6 women who delivered during the study period. Conclusions: In contrast with the reports from Western countries, pandemic (H1N1)2009 among pregnant Korean women was mild.

Methicillin 내성 포도알균에 의한 정형외과감염 치료에 사용되는 경구 항균제

김백남 대한감염학회 2011 Infection and Chemotherapy Vol.43 No.4

Orthopedic infections, especially implant-associated infections, are difficult to treat. Long-term oral antibiotic, along with appropriate surgery, is often needed to eradicate infections. The question still remains which antibiotic regimen is best in this setting because of a paucity of large comparative clinical trials. I reviewed in vitro and in vivo studies evaluating the effectiveness of various oral antibiotic regimens of monotherapy or combination therapy for orthopedic infections caused by methicillin-resistant staphylococci.

IgE매개 세팔로스포린 과민반응

김백남,조유숙 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Cephalosporins are commonly prescribed either orally or parenterally for the treatment of bacterial infections because of wide safety margin compared with penicillins. Skin testing with a parent cephalosporin antibiotic has routinely been performed in Korea in the fear of developing anaphylaxis after the administration of a cephalosporin although penicillins are antibiotics that most commonly induce severe or life-threatening IgE-mediated reactions (anaphylaxis). In this review, we will discuss IgE-mediated hypersensitivity reactions to cephalosporins. Immunopathogenesis of IgE-mediated hypersensitivity reaction to cephalosporins, limitations of skin testing with parent cephalosporin antibiotics, and prescription strategy of cephalosporins for patients with a history of cephalosporin or penicillin hypersensitivity was described.

IgE매개 세팔로스포린 과민반응

김백남,조유숙 대한감염학회 2010 Infection and Chemotherapy Vol.42 No.3

Cephalosporins are commonly prescribed either orally or parenterally for the treatment of bacterial infections because of wide safety margin compared with penicillins. Skin testing with a parent cephalosporin antibiotic has routinely been performed in Korea in the fear of developing anaphylaxis after the administration of a cephalosporin although penicillins are antibiotics that most commonly induce severe or life-threatening IgE-mediated reactions (anaphylaxis). In this review, we will discuss IgE-mediated hypersensitivity reactions to cephalosporins. Immunopathogenesis of IgE-mediated hypersensitivity reaction to cephalosporins, limitations of skin testing with parent cephalosporin antibiotics, and prescription strategy of cephalosporins for patients with a history of cephalosporin or penicillin hypersensitivity was described.

쯔쯔가무시병에서 가피의 위치와 복장과의 관계

김백남,곽이경,문치숙,김의석,박상원,이창섭 대한감염학회 2006 Infection and Chemotherapy Vol.38 No.6

혈액배양검사의 원리와 실제

김백남 대한감염학회 2007 Infection and Chemotherapy Vol.39 No.3

Blood cultures are the gold standard for diagnosing bloodstream infections and identifying causative organisms. Every effort should be made to improve diagnostic yield, and obtained results should be interpreted cautiously in the context of clinical findings. In this review, several issues of clinical relevance with regard to blood culturing are addressed; these issues include indications, skin antisepsis, timing and number of blood cultures, volume of obtained, and interpretation of positive blood culture results.

우리나라 항생제 사용 실태

김백남 대한감염학회 2012 Infection and Chemotherapy Vol.44 No.4

Antibiotics are one of the most commonly produced pharmaceutical agents;production amount of antibiotics reached approximately 1.6 trillion won in 2010. From the doctors’ perspective, there were important turning points in the use of antibiotics beyond the 21st century. These include implementation of separation of pharmaceutical prescription and dispensation in 2000, quality assessment of prescriptions, including those for antibiotics for treatment of acute upper respiratory tract infections, in ambulatory care in 2001 and public reporting of its results in 2006, quality assessment of the use of prophylactic antibiotics for surgery in 2007,and the code of conduct for ethical competition in the pharmaceutical trade in 2010. With this background, many changes in the use of antibiotics have occurred in the last decade. This review summarizes the literature published on the use of antibiotics in human medicine in Korea over the past decade.

2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 Infection and Chemotherapy Vol.42 No.2

The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65years or more of age were classified into group I to VI, respectively. A total of 107,467visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009)was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

2009년 인플루엔자 대유행 중 인플루엔자 진료소 방문자의 연령 분포 변화

김백남,곽이경,문치숙,김연숙,김의석,배인규,염준섭,이창섭,허지안 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

The pandemic influenza (H1N1 2009) virus, after being introduced in Korea in April, 2009, spread rapidly nationwide in mid-2009. This study was conducted to characterize trend in age distribution of visitors to Flu-clinics during the pandemic. Demographic, clinical and laboratory data of visitors to flu clinic from Week 36 to 52 (August 30 to December 26) of 2009 were retrieved and collected from electronic databases at 9 hospitals. Visitors 0-6, 7-12, 13-18, 19-29, 30-64, and 65 years or more of age were classified into group I to VI, respectively. A total of 107,467 visitors were seen at Flu-clinics for a 17-week study period. Of those, 32,485 were laboratory-confirmed. Antivirals were prescribed for 62,533 visitors. Numbers of visits, prescriptions of antivirals, and laboratory-confirmed cases of the pandemic influenza (H1N1 2009) peaked at Week 44. A large number of visits by group II and III were followed by those of group I and V, especially around the peak. Numbers of visits by group VI were lowest in all hospitals. In some hospitals, higher number of visits lasted longer in children than in adults while vice versa in other hospitals depending on the location. In summary, the pandemic influenza (H1N1 2009) was presumed to peak in late October and involved majorly children and students in Korea. Unique age distribution of visitors to flu clinic was observed in some hospitals.

일차 진료 외래 환자의 발열

김백남 대한내과학회 2022 대한내과학회 추계학술대회 Vol.2022 No.1