심실중격결손증-치험 1예-

조광현,우종수,황윤호,이양행,박철호,김종성,김철호,이경순,조영일,박태인 인제대학교 1985 仁濟醫學 Vol.6 No.4

A successful treatment of infants and children with congenital heart defects depends upon several factors: diagnosis must be accurate, the operative technique, including techniques of perfusion and myocardial preservation, must be suited to the needs of patients and intensive cares, including accurate anesthesia, must be applied through all stages of investigation and treatment, i.e. before, during and after the operation. Recently we performed a open heart surgery successfully for a six-years old girl who had suffered from frequent upper respiratory tract infection and mild to moderate exertional dyspnea with congenital heart defects (ventricular septal defect, Kirklin type II, with patent foramen ovale). The operation and postoperative course were very smooth. And now we report this with review of literatures.

플라즈마 표지소자의 제작

이상윤,라병욱,박동수,황인헌,이덕동,신영남,박성배,이동욱,박용석,박형근,손상호,권태근,채경락,정경득 慶北大學校 自然科學大學 1986 自然科學論文集 Vol.4 No.-

An Ac-type Plasma Display Panel (PDP) operating with Ne-Ar(0.1%) Penning mixture gas is fabicated. The characterics of the panel with electrodes covered with thin and thick dielectric layers are studied. The brightness of the Neon-orange light emitted by the panel measured as function of applied voltage and frequency. As an application, a graphic display system equipped with PDP showing still and moving pictures is made.

Mode I Problems of Localized Crack Closure Due to Nearby Concentrated Forces

Kyung Hyun Whang 대한기계학회 1987 대한기계학회 춘추학술대회 Vol.- No.-

4-Pentenoic Acid로 유발시킨 라이증후군 흰쥐의 뇌에서 GFAP면역반응성 성상교세포의 변화

양현억, 황경태(Hyun-Eog Yang, Kyung-Tai Whang) 대한소아신경학회 1996 대한소아신경학회지 Vol.3 No.2

4-pentenoic acid(4-Pa)로 유발시킨 실험적 라이증후군 흰쥐에서 교세포원섬유성 산성단백질(GFAP)항체를 이용한 광학 및 전자현미경적면역세포화학법으로 대뇌와 소뇌의 피질 및 수질에 분포하는 GFAP양성 성상교세포를 감별 염색하여 그 면역반응성과 이들이 차지하는 면적 비율을 계측하여 성상교세포에서의 GFAP활성도를 확인하고, 아울러 이들 미세구조적 변화를 관찰하여 다음과 같은 결과를 얻었다. 4-PA를 투여한 동물에서 투여후 40-80분 사이에 모두 경련발작을 일으켰으며, 4-PA투여후 30분에 혈당값은 정상대조군 것에 비하여 유의하게 감소하였고, SGOT값과 혈중 암모니아값은 정상대조군 것에 비하여 유의하게 증가하였다. 4-PA를 투여한 동물의 대뇌에서 대상속에 분포하는 GFAP양성 성상교세포의 GFAP면역반응성과 면적비율은 정상군 것에 비하여 다같이 유의한 증가를 나타내었다. GFAP항체를 이용한 면역전자현미경적 관찰에서 볼 때 성상교세포의 세포질에 있는 중간세사가 선택적으로 염색되었으며, 이들 중간세사는 4-PA투군의 대뇌 및 소뇌 성상교세포에서 현저히 증가하였다. 이상의 관찰결과로 미루어 볼 때 4-PA에 의한 실험적 라이증후군에서 조기에 대뇌 및 소뇌에 분포하는 성상교세포의 GFAP발현과 중간세사가 현저히 증가하며, 이와 같은 현상은 라이증후군에서 대상적 반응성 성상교세포중의 한 양상으로 생각된다. Background: 4-pentenoic acid(4-PA) has been known to be a useful neurotoxin to produce most of the essential features of Reye's syndrome in rats, but little has been studied about the effects of this reagent on the changes of the glial fibrillary acidic protein(GFAP) immunoreactivity of astrocytes in the central nervous system. We designed this study in order to clarify the alterations of the GFAP-immunoreactivity, area percent and ultrastructure of GFAP-positive astrocytes in the brain of the rat with experimental Reye's syndrome by light and electron microscopic immunocytochemistry using anti-GFAP antiserum. Method: Reye's syndrome was induced by intraperitoneal injection every 4 hr with 50mg/kg body weigh of 4-PA for 10 doses, followed by a single dose of 200mg/kg. Animal were sacrificed in 30 minutes after th final injection, and tissue blocks were taken from the cerebrum and cerebellum. Paraffin sections were immunostained with the indirect immunoperoxidase method for light microscopy, and the area percent of GFAP-positive astrocytes was calculated using the image analysis system(Vidas 2.0, Kontron, Germany) in the immunostained sections. For electron microscopy, pre-embedding immunocytochemical method was applied Result: During the experimental period, all rats were observed clinical features similar to those of the Reye's syndrome, including convulsion, hyperammonemia, hypoglycemia and elevated SGOT. The GFAP immunoreactivity and the area percent of GFAP-positive astrocyte in 4-PA-treated animals were significantly increased in cerebral cingulum and cerebellar cortex and medulla, as compared with those of normal control. The increment was highly signigicant in cerebellum than in cerebrum. However, the intensity was observed to be slight in frontal cortex. The intermediate filaments in the cytoplasm of astrocytes were selectively immunostained by the electron microscopic immunocytochemistry and these GFAP-immunoreactive intermediate filaments were markedly increased in both cerebral and cerebellar astrocytes of the 4-PA treated animals. Conclusion; These observations elucidate that the increment of GFAP expression and intermediate filaments in the astrocytes of cerebrum and cerebellum are striking feature in the early stage of Reye's syndrome induced by 4-PA, and suggest that the compensatory reactive astrocytosis is consequently involved in the encephalopathy.

光合成 細菌 T-20株의 同定

玄文湜,黃敬淑,申寬澈 충남대학교 농업과학연구소 1992 농업과학연구 Vol.19 No.1

Phototrophic bacteria T-20 investigated in the present report was isolated from Thailand oil, Cells of the bacterium were rod-shaped. measured 0.6∼0.7㎛ wide, and 2.3㎛ long. A color of cell suspension was red, and the long wavelength absorption maxima of the bacteriochlorophyll measured in 870㎚. Substrates utilized as carbon sources: citrate, aspirate, glutamate, and fructose: unique for this strain is the liquefaction of gelatine, Ubiquinone Q-8 was also found. Rhodocyclus gelatinosus, which was reported in Bergey's Manual of Systematics Bacteriology, was corresponded to T-20.

梓木이 腦血流 및 血壓에 미치는 影響

황경택,경은호,나한일,소응향,최병화,한종현 한국전통의학연구소 2003 한국전통의학지 Vol.13 No.1

The purpose of this study is to measure the changes of regional cerebral blood flow (rCBF) and blood pressure (BP) in rats, following the intravenous injection of Catalpa Ovata Water Extract (COWE). The measurement was continually monitored by laser-doppler flowmeter (Transonic Instrument, USA) and pressure tranducer(Grass, USA) in anesthetized adult Sprague-Dawley rats through the data acquisition system composed of MacLab and Macintosh computer. The result of this experiment was as following : COWE increased the changes of rCBF and BP significantly. After pretreatment with propranolol and indomethacin, the changes of rCBF were inhibited significantly, but not by L-NNA and methylene blue. Also, after pretreatment with propranolol, the changes of BP were inhibited significantly, but not by L-NNA, methylene blue and indomethacin. According to above result, it is considered that Catalpa Ovata increased the rCBF and BP, related to adrenergic β-receptor.

Penicillin이 포도구균 세포벽 형성에 미치는 전자현미경적 연구

황준경,최대경,박정규,백태현 충남대학교 의과대학 지역사회의학연구소 1986 충남의대잡지 Vol.13 No.2

Electron microscopy of morphological changes in Staphylococcus aureus induced by penicillin and vancomycin which interfere with cell was synthesis revealed morphological alterations which correlated well with their mechanism of action. And the studies also were undertaken to investigate alterations in surface morphology resulting from the action of gentamycin known to interfere with intracellular protein synthesis. Cultures of Staphylococcus aureus were exposed to penicillin G(1/2 MIC), vancomycin(1/2 MIC) and gentamycin(1/2 MIC) for 5 hours at 37℃. The following results were obtained; 1. Subinhibitory concentration of penicillin G(1/2 MIC) do not kill Staphylococcus aureus, they were induced the cell surface depression, large and small cell formation. 2. In the exposure to 1/2 the MIC of penicillin G, the cross wall was much wider than in the control, 1/2 the MIC of penicillin G have appeared to inhibit cross wall lysis in Staphylococcus aureus. 3. The effects of 1/2 MIC of vancomycin on Staphylococcus aureus revealed the small surface depression, but the cross wall are normal appearance. 4. Specific abnormalities of Staphylococcus aureus by 1/2 MIC of gentamycin are not evident.

Vascular Dementia 에 關한 韓醫學的 臨床硏究

현경철,김종우,황의완 대한한방신경정신과학회 1999 동의신경정신과학회지 Vol.10 No.1

In order to confirm the efficiency of Oriental medical treatment on Vascular dementia, 24 probable and possible vascular dementia patients diagnosed by ADDTC criteria, were chosen and followed among the patients who had visited KOMC from April, 1996 to March, 1997. They were given herbal and acupuncture therapy, mainly focused on circulating qi(順氣)and removing phlegm(治痰) which is generally applied in early stage of cerebro-vascular disease, and then assessed by the improvement of stage according to the level of impairment, as proposed by APA. The results were as followed. 1. Out of 25 cases, 8 patients showed 2 grade improvement(++), 15 patients showed 1 grade improvement (+), and 1 patient showed no change. 2. The efficiency of treatment is higher when they're given treatment earlier. 3. The efficiency of treatment is higher when their symptoms are lighter. In conclusion, this study shows meaningful effect of Oriental medical treatment on vascular dementia and also shows that It's more effective in the case of short onset and mild symptom.

制酸製에 關한 硏究(第一報)

황용희,이경아,강인자,주현숙 梨花女子大學校 藥學硏究所 1967 梨花藥學硏究 Vol.- No.8

This is a preliminary experiment of the study in which the copricipitation between Magnesium and Aluminium will be taken. As sample we prepared several kinds of mixture of mocular ration between Magnesium and Aluminium, and measure the neutralizing capacity, rapidity and prolonging time for 0.1N-HC1.

대퇴골 근위부 형태의 연령별 차이에 관한 연구

구경회 ( Kyung Hoi Koo ),조세현 ( Se Hyun Cho ),이종서 ( Chong Suh Lee ),송해룡 ( Hae Ryong Song ),박형빈 ( Hyung Bin Park ),정연천 ( Yeon Chun Jung ),황선철 ( Sun Chul Whang ) 대한고관절학회 1992 Hip and Pelvis Vol.4 No.2

The shape of the proximal femoral endosteal canal is so different with age, sex and individual variation that any one contemporary stem cannot afford adequate fitting for all cases. Therefore the accurate knowledge of variability of proximal femoral canal and its chronological change is essential for the selection of the most adequate stem design and prediction of the fate of stem after hip replacement arthroplasty. Total 300 radiographs of proximlal femur (50 cases for each decade, from 3rd decade to 8th) were reviewed for the chronological anthropometric study of proximal femoral geometry and the below results were obtained. 1. The maximum cortical thickness at isthmic level was observed in the 5th decade (9.8+- 1.5mm), with gradual decreament, after then(8.9+-1.9mm in the 8th decad). 2. The endosteal canal ratio at the isthmic level revealed continuous increament from the 3rd decade (0.38+-0.08 in the 3rd decade, 0.44+-0.08 in the 8th decade). 3. About the canal flare index and the stem space flare index, their maximum values were in the 4th decade(4.5+-0.9 and 3.2+-0.6)and decreased gradually(3.5+-0.6 and 2.5+- 0.5 in the 8th decade).