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장정욱,박춘식,장일석 국립7개대학공동논문집간행위원회 2004 공업기술연구 Vol.4 No.-
This study investigated the settlement of soft ground caused by fill-loading. The S.C.P replacement ratio(a_(s)), range(S_(0)/B), and depth(h_(0)/H) were taken as variables. The conclusions are presented in the following. (1) As a_(s), S_(0)/B, and h_(0)/H increases, the maximum settlement decreases. However, the maximum settlement is less in S_(0)/B than in as, and h_(0)/H. (2) Changes in the maximum settlement are relatively great in the range of h_(0)/H = 0.2~0.6, but small in the case of h_(0)/H>0.6. (3) The reducing rate becomes different when a_(s) = 30%, and S_(0)/B = 0.6. (4) When a_(s) = 10%, the maximum settlement due to the increase in replacement depth reduces little relatively to other replacement ratios.
흰쥐 생체시료 중 5-플루오로우라실 및 테가푸르의 안정성
장지현,박종국,강진형,정석재,심창구,구효정 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.3
5-Fluorouracil (5-FU) is an antimetabolite anticancer agent active against many types of solid tumors. Tegafur (TF), a prodrug of 5-FU, is frequently used in combination with uracil as dihydropyrimidine dehydrogenase (DPD) inhibitory fluoropyrimidine. We studied the stability of 5-FU and TF in biological fluids of rats and determined their bioavailability (BA) and excretion into bile, and urine. The drug concentrations were analyzed by an HPLC method. At room temperature, there was a 14-30% decrease in the concentration of 5-FU and TF in bile, urine, and plasma specimen at 10 and 100 μg/ml over 240 min. No significant difference was noted among the sample types or between two different concentrations of 10 and 100 μg/ml. The decrease in drug concentration was significantly less in samples kept on ice (6-12%) for both drugs. These data indicate that biological fluid samples containing 5-FU or TF in plasma, urine, or bile should be placed on ice during the sample collection. Following these storage guidelines, samples were collected after administration 50 ㎎/㎏ of each drug via i.v. or oral route. BA was 1.5 folds greater for TF (60%) than that of 5-FU (42%). Approximately 0.52 and 3.3% of the i.v. doses of 5-FU and TF was excreted into bile, respectively. Renal clearance of 5-FU was about 16% of its total body clearance. These results suggest that instability of 5-FU and TF in biological fluids should be considered in pharmacokinetic or pharmacogenomic studies.
측방유동 저감을 위한 Pile Slab의 적용성에 관한 연구
장정욱,박춘식,장일석 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-
This study analyzed the reductive effect of lateral flow by the section and height of reinforcement of Pile Slab. The conclusions of the study are as follows. (1) The lateral flow of abutment increased linearly as the reinforcement section decreased. (2) The lateral flow of abutment showed the minimum value when the reinforcement height was 0.5h~0.6h. (3) The reinforcement section was found to have a close relationship with the reinforcement height. We conclude that more economical reinforcement methods would require consideration of this relationship between the two variables.
학령전기 여아의 하반신 체형 유형분석 : 부산 및 경남지역을 중심으로
장정아,권영숙 服飾文化學會 2000 服飾文化硏究 Vol.8 No.6
This study was done to provide the fundamental data for scientific and rational children's clothing sizing system by investigating their somatometric characteristics and classifying somatotypes. The subjects were 269 elementary schoolgirls aged from 7 to 8 years old living in Pusan and Kyungsangnam-do. Data from each girl comprises 28 anthropometic measurments and 4 photographic measurments, related to the lower half of body. To analyze somatotypes of the lower half of body, factor analysis, cluster analysis, discriminant analysis were performed far statistical analysis of the data. As to the analysis to draw somatometric factors by this age group, five factors which explain 76.85% of the whole variances were extracted. The first and second factors which explain more than 60% of the whole variances represent 'horizontal size' and 'vertical size', which characterize most aspects of the body shape of the subjects. On the basis of the cluster analysis, three different lower half of body types were categorized. Type I has biggest horizontal size, average vertical size and most protruded belly. Type Ⅱ has average decree of horizontal size, quite big vertical size and most protruded hips. Type Ⅲ has smallest horizontal and vertical size. According to the analysis to discriminate somatotypes of the lower half of body of this age group, weight and waist circumference of discriminant function 1 and abdominal circumference of discriminant function 2 have coefficient values.
Plyometric Training과 비타민 C 투여가 남고생의 체력, 혈중 젖산, 암모니아 및 젖산탈수소효소에 미치는 영향
장준원,김세종,이현미,서혜림,조현숙,고정림,염종우,예정복,백영호 釜山大學校 附設 體育科學硏究所 2003 體育科學硏究所 論文集 Vol.19 No.-
The purpose of this was to examine the effect of plyometric training and vitamin C ingestion on physical fitness and fatigue substance....
철근비, 세장비 및 강도에 따른 철근콘크리트 기둥의 좌굴거동에 관한 실험적 연구
김광석,장정수 조선대학교 국토개발연구소 1997 국토개발연구 Vol.17 No.1
As most of the study for columns have been carried out analytically by solving the governing differential equation of columns, the prediction of behavior of columns is almost impossible when the columns exist as a part of complex structure. To study experiment of the behavior of reinforced concrete columns with normal and high strength, the 80mm square cross section was used and the amount of eccentricity was 24mm. The compressive strengths of column specimens with slenderness ratios of 10, 60 and 100 were 260, and 879kgf/㎟. The longitudinal steel ratio of columns with bending about a section diagonal and about a principal axis were 1.98%(4-D6) and 3.95%(8-D6). The ratio of ultimate load capacity to that of short column with the same eccentricity was much decreased at high slenderness ratio with increasing the compressive strength of concrete. And the lateral displacement of slender column at the ultimate load was decreased as the strength was increased.
콘크리트의 파괴에너지 결정을 위한 3점 휨시험과 compact compression 시험의 비교 연구
김광석,장정수 朝鮮大學校 建設技術硏究所 1998 建設技術硏究 Vol.18 No.2
This paper studied on compact compression test which can calculate fracture energy by the smallest specimen and three point bending test of the most stable system which have regular thickness and inital crack. This study supposed that width W_(c) of microcrack zone is propotioned to "n" thimes of maximun aggregate size, and that derived size effect expression is propotioned to "nd^(m)_(a)". This paper could derive following conclusion as studying and researching reference and data of this experimentation, and as deriving new size effect law through dimensional analysis and similitude law. New size effect expression derived from expression which consider maximum aggregate size on the basis of strength criterion and energy criterion through dimensional analysis and similitude law. The effect of maximum aggregate size to width of microcrack zone was proportioned to rater "nd^(m)_(a)" than "n" times of maximum aggregate size da through reference and experimentation of this paper. This paper shows that concrete fracture energy G_(f) supposed in new model is accord with fracture energy by BKP method, also shows that we can get the long-awaited fracture energy fully for by CCS because specimen by three-point bending test is well accord with theoretical size on fracture energy of specimen by compact compression specimen each other.
서정국,장석환 白中央醫療院 2005 仁濟醫學 Vol.26 No.1
Intradural extramedullary tumors grow slowly and can have various clinical manifestations depending on their location in the spine. They often mimic other spinal disorders thus delaying the diagnosis. These tumors are usually histologically benign and can be resected with complete extirpation and have excellent prognosis. We report a case of intradural extramedullary schwannoma which was initially diagnosed as spondylolisthesis of the lumbar spine with review of pertinent literature.
이장렬,신인숙,박창서,조정신 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.1
Cystic hygroma is a special form of lymphangioma. It most often occurs in the neck of children. We observed a 14-year-old male whose chief complaint was a abnormal swelling of the right mandibular angle area. The computerized tomography showed the well-defined nonenhancing cystic mass on right submandibular gland areaand anterior triangle of the neck. The histopathologic fidings exhibited the multiloculatedfluid-filled cysts, which are lined a flattened layer of endothelial cells with foci of lymphocytes found lying adjacent to the lining. After evaluation of above findings, the mass was diagnosed as a cystic hygroma in the neck.