체육수업 설계에 대한 고등학생의 기대요구 분석

이정흔,오병돈,조민행,유영설,이명선,조병준 韓國學校保健學會 2009 韓國學校保健學會誌 Vol.22 No.2

Purpose: The purpose of this study was to analyze students' expectance demand towards high school physical education teaching. Methords : 392 participants randomly selected from one girls' middle school and one girl's high school in each of five tracts and then selected two classes from each of the schools. They were asked to respond to a simple Questionnaire about their views on the present physical education teaching. Results : Results showed that about one third of the participants would not choose physical education if the program were offered as an optional subject. Both male and female students ranked psychomotor domain as the top priority among the various learning objectives. Male students favored soccer and basketball while their counterparts liked badminton and volleyball. Over three-fourths of the participants suggested that students' opinions should be considered when teachers plan their program. Conclusion : The results of this study recommended that physical education teaching should be designed with considerations for professional values, societal changes as well as students' expectance on the design of physical education.

정신분열증 환자의 신체증상과 인구통계학적, 임상인자들과의 관련성

윤정흠,김선경,전현태,이귀행 원광대학교 의과학연구소 2009 圓光醫科學 Vol.24 No.1

배경 : 이 연구의 목적은 정신분열병 환자의 신체증상과 인구통계학적, 임상인자들과의 관련성을 알아보기 위함이다. 방법 : 연구 대상군은 입원중인 63명의 정신분열병 환자를 대상으로 하였다. 신체 증상의 정도는 한국어판 신체증상목록을 사용하여 측정하였다. SPSS 11.5를 이용하여 신체증상의 정도와 우울, 불안, 교육정도, 적응상태와의 관계를 피어슨 상관분석을 통하여 평가하였다. 결과 : 1) 신체증상의 정도는 교육기간과 입원 당시의 적응 상태와는 부적 상관을 보였다(p<0.05). 2) 신체증상의 정도는 우울, 불안과는 정적 상관을 보였다(p<0.05). 3) 정신분열병 환자의 신체 증상의 빈도는 다음 순이었다: 두통, 피로, 수면장애, 건강염려, 현기증, 오심, 위장장애, 근력 약화, 허리나 등의 통증, 복부의 가스. 결론 : 정신분열병의 신체증상의 정도는 교육기간이 길고 입원 당시의 적응상태가 좋을수록 감소하였다. 그리고 신체 증상은 우울, 불안의 증상이 심할수록 증가하였고, 이는 특히 신체증상이 우울, 불안과 관련이 있다는 것을 알 수 있었다. Background : The purpose of this study was to examine the correlation between somatic symptoms and demographic and clinical variables in schizophrenia patients. Methods : The subject were 63 schizophrenia patients ; male(n=35, mean age =39), female(n=28, mean=age 40). The degree of somatic symptoms was measured using the Korean versions of Wahler Physical Symptom Inventory(WPSI). The relationship among somatic symptoms, anxiety, depression, education period and adjustment was evaluated by Pearson correlation with SPSS 11.5. Results : 1) The degree of somatic symptoms showed negative correlation with education period and current adjustment at admission(p<0.05). 2) The degree of somatic symptoms was significantly correlated with degree of the depression and the anxiety(p<0.05). 3) The frequent somatic symptoms were as follows in order : headaches, feeling tired, difficulty sleeping, poor health in general, dizzy spells, nausea, intestinal or stomach trouble, muscular weakness, backaches and excessive gas. Conclusion : The somatic symptoms of schizophrenia were decreased in the group of the long education period and the good current adjustment at admission. The more depression and anxiety were increased, the more somatic symptoms were revealed. It suggests that somatic symptoms of schizophrenia may be related to depression and anxiety.

대혈관 전위증의 병리

조수연,오미혜,김정선,이용희,강행지,서정욱 한국소아심장연구회 2003 소아심장 Vol.7 No.2

정신분열병 환자의 인지기능 상태

이지혜,오소영,윤정흠,김선경,이귀행 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.1

목적: 정신분열병 환자의 적응 상태와 증상 형성에 영향을 주는 것으로 생각되는 인지기능 상태를 주의력, 형태 인식, 단어에 대한 구별과 종합 기능을 평가해봄으로써 알아보고자 하였다 방법: 정신분열병 환자 27명과 대조군 27명을 대상으로 하였고, 평가 도구로써 주의력은 K-WAIS의 숫자외우기 문제로, 형태 인식은 K-WAIS의 모양 맞추기 문제와 숨은 그림 찾기로, 단어 기능은 K-WAIS의 공통성 문제와 단어 차이 검사로 각각 이루어졌다. 통계 처리는 SPSS 11.5를 이용하여 Chi-Square test와 Student's t-test로 검증을 하였다. 결과: 정신분열군은 숫자외우기, 숨은 그림 찾기, 모양 맞추기에서는 대조군보다 낮은 점수를 보였다. 단어 차이 검사와 공통성 문제에서는 양군에서 차이를 보이지 않았다. 결론: 본 연구에서 정신분열군의 인지 기능은 정상인 대조군에 비해 주의력과 형태 인식 기능이 유의하게 떨어져 있었으며, 단어들을 구분하고 종합하는 능력은 차이가 없었다. 이런 결과는 임상적으로 정신분열병에서 보이는 망상이 언어적인 측면에서는 어느 정도 전달이 되는 현상과 일치하지만 주의나 형태인지와 같은 기본적인 과정에서 장애가 있다는 추정을 하게 한다. Purpose: This study aimed to investigate the cognitive function in patients with schizophrenia by assessing attention, recognition of a shape, and verbal function. Methods: The subjects were 27 patients with schizophrenia group and 27 control group. Attention was assessed by the digit span task(K-WAIS subtest). The recognition of a shape was assessed by the object assembly task(K-WAIS subtest) and hidden figure task. Verbal function was assessed by Similiarities(K-WAIS subtest) and the different word task. Analysis was performed by the Chi-Square test and Student's t-test via SPSS 11.5. Result: Schizophrenia group had statistically lower scores than control group in digital span, hidden figure and object assembly. There was no difference between two groups in dimensions of difference in words and similarity. Conclusion: This study showed that patients with schizophrenia had impairments in attention and recognition of shape, and no difference between two groups in verbal ability. These explained the partial communicative function of delusion in verbal level. The formation of delusion might be related to the more basic elements such as attention and recognition of shape.

실활치 변색의 치료

정선주 ( Sun Ju Jeong ) , 오행진 ( Haeng Jin Oh ) , 김정호 ( Jeong Ho Kim ) 조선대학교 구강생물학연구소 2004 Oral Biology Research (Oral Biol Res) Vol.28 No.2

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실활치 변색의 치료

정선주 ( Sun Ju Jeong ),오행진 ( Haeng Jin Oh ),김정호 ( Jeong Ho Kim ) 조선대학교 구강생물학연구소 2004 口腔生物學硏究 Vol.28 No.2

Overexpression of the <i>IbMYB1</i> gene in an orange‐fleshed sweet potato cultivar produces a dual‐pigmented transgenic sweet potato with improved antioxidant activity

Park, Sung‐,Chul,Kim, Yun‐,Hee,Kim, Sun Ha,Jeong, Yu Jeong,Kim, Cha Young,Lee, Joon Seol,Bae, Ji‐,Yeong,Ahn, Mi‐,Jeong,Jeong, Jae Cheol,Lee, Haeng‐,Soon,Kwak, Sang‐ Blackwell Publishing Ltd 2015 Physiologia plantarum Vol.153 No.4

<P>The R2R3-type protein IbMYB1 is a key regulator of anthocyanin biosynthesis in the storage roots of sweet potato [Ipomoea batatas (L.) Lam]. Previously, we demonstrated that IbMYB1 expression stimulated anthocyanin pigmentation in tobacco leaves and Arabidopsis. Here, we generated dual-pigmented transgenic sweet potato plants that accumulated high levels of both anthocyanins and carotenoids in a single sweet potato storage root. An orange-fleshed cultivar with high carotenoid levels was transformed with the IbMYB1 gene under the control of either the storage root-specific sporamin 1 (SPO1) promoter or the oxidative stress-inducible peroxidase anionic 2 (SWPA2) promoter. The SPO1-MYB transgenic lines exhibited higher anthocyanin levels in storage roots than empty vector control (EV) or SWPA2-MYB plants, but carotenoid content was unchanged. SWPA2-MYB transgenic lines exhibited higher levels of both anthocyanin and carotenoids than EV plants. Analysis of hydrolyzed anthocyanin extracts indicated that cyanidin and peonidin predominated in both overexpression lines. Quantitative reverse transcription-polymerase chain reaction analysis demonstrated that IbMYB1 expression in both IbMYB1 transgenic lines strongly induced the upregulation of several genes in the anthocyanin biosynthetic pathway, whereas the expression of carotenoid biosynthetic pathway genes varied between transgenic lines. Increased anthocyanin levels in transgenic plants also promoted the elevation of proanthocyanidin and total phenolic levels in fresh storage roots. Consequently, all IbMYB1 transgenic plants displayed much higher antioxidant activities than EV plants. In field cultivations, storage root yields varied between the transgenic lines. Taken together, our results indicate that overexpression of IbMYB1 is a highly promising strategy for the generation of transgenic plants with enhanced antioxidant capacity.</P>

Prognostic significance of lymphovascular invasion in patients with prostate cancer treated with postoperative radiotherapy

Jeong, Jae-Uk,Nam, Taek-Keun,Song, Ju-Young,Yoon, Mee Sun,Ahn, Sung-Ja,Chung, Woong-Ki,Cho, Ick Joon,Kim, Yong-Hyub,Cho, Shin Haeng,Jung, Seung Il,Kwon, Dong Deuk The Korean Society for Radiation Oncology 2019 Radiation Oncology Journal Vol.37 No.3

Purpose: To determine prognostic significance of lymphovascular invasion (LVI) in prostate cancer patients who underwent adjuvant or salvage postoperative radiotherapy (PORT) after radical prostatectomy (RP) Materials and Methods: A total of 168 patients with prostate cancer received PORT after RP, with a follow-up of ≥12 months. Biochemical failure after PORT was defined as prostate-specific antigen (PSA) ≥0.2 ng/mL after PORT or initiation of androgen deprivation therapy (ADT) for increasing PSA levels regardless of the value. We analyzed the clinical outcomes including survivals, failure patterns, and prognostic factors affecting the outcomes. Results: In total, 120 patients (71.4%) received salvage PORT after PSA levels were >0.2 ng/mL or owing to clinical failure. The 5-year biochemical failure-free survival (BCFFS), clinical failure-free survival (CFFS), distant metastasis-free survival (DMFS), overall survival, and cause-specific survival rates were 78.3%, 94.3%, 95.0%, 95.8%, and 97.3%, respectively, during a follow-up range of 12-157 months (median: 64 months) after PORT. On multivariate analysis, PSA level of ≤1.0 ng/mL at the time of receiving PORT predicted favorable BCFFS, CFFS, and DMFS. LVI predicted worse CFFS (p = 0.004) and DMFS (p = 0.015). Concurrent and/or adjuvant ADT resulted in favorable prognosis for BCFFS (p < 0.001) and CFFS (p = 0.017). Conclusion: For patients with adverse pathologic findings, PORT should be initiated as early as possible after continence recovery after RP. Even after administering PORT, LVI was an unfavorable predictive factor, and further intensive adjuvant therapy should be considered for these patients.

세균의 항생제 내성 현황에 대한 모니터링(모니터링 사업) : Monitoring on the Bacterial Resistance to Antibiotics

정혜윤,장성제,공학수,장정윤,최선옥,신행섭,이경희,김광욱,이경원,김은정 식품의약품안전청 2000 식품의약품안전청 연보 Vol.4 No.-

국내에사 항생제 오남용으로 세균의 항생제 내성률이 세계적으로 높은 수준에 이르러 있는 현재 상팡에서, 병원 환자 및 일반인에서 세균의 내성 전파 현황을 파악하기 위하여 병원 환자 및 일반인에서 분리된 왔색포도상구균에 대하쳐 치료항생제에 대한 내성 현황을 모니러링하였다. 2000년에 3차 의료기관의 환자에서 분리된 황색포도상구균 279균주에 대하여 디스크 확산법에 의하여 항생제 내성를을 조사한 결과, penicillin 내성 띤%, oxacillin 내성 78%, cephalothin 내성 74%, gentaudcin 개성 79%, tetracycline 내성 76%, erythromycin 내성 84%, clindamycin 내성 73%, o뵈oxacin 내성 75%,sulfamethoxazole-Uirnethoprinl (cotrimoxazole) 내성 5%, ohlorarnphenicot 내성 3%, 및 vancomycin 내성 0% 였다. 또한 2000년에 3차 의료기관의 환자에서 분리된 황색포도상구균 107근주에 대하여 최소억제농도 (Hrifmum infibitory concentration, MIC) 측정법에 파라 항생제 내싶률을 조사한 결과, pe굻cillin 내성 59%, oxacillin 내성 80%, erythromycin 내성 실%, tetracycline 내성 76%, gentarlicin 내성 71%, cephalothin 내성 79%, of loxacin 내성 79%, vancomycin 내성 0% 였다. 반면 2000년에 건강할 일반인(498명)(3~71세)의 비강으로부터 분리된 황색포도상구균 130균주 (Baird parker agar배지(Difco)에서 선택적으로 분리 후 황색포도상구균의 확인시헝실시)에 대하여 디 스크 확산법에 따라 치료항생제에 대한 내성를을 측정한 결과 penicillin 내성 95%, oxacillin 내성 2%,cephalothin 내성 1%, gentainicin 내성 11%, tetracycline 내성 긴%, erythromycin 내성 뽀%,cl고damycin 내성 2%, o친oxacin 내성 0%, sulfamethoxazole-trimethoprim 내성 0%, ehlorarn-phenicol 내성 1%, amoxicillin·-clavulanic acid 내성 1%, vancomycin 내싱 0% 였다. 이상의 결과로 부터 지역사회의 일반인으로부터 분리된 황색포도상구균은 penicillin, erythromycin, tetracycline,gentamicin 순으로 내성이 높았던 것으로 나타났다. In the situation of high bacterlal resistance in Korea, to assess diffusion of methicillin-resistant ffoffyforfccus oureus (MRSA) and levels of bacterial resistance toantibiotics in hospital patients and community, we monitored antibiotic resistance of 5. aureusisolates from hospital patients and llealthy volunteers of community. From disc diffusion tesf on279 5. aureus isolates from'hospital patients in 2000, the resistance rates were as follows;penicillin resistant, 99%; of acillin resistant (bfRSA), 78%; cephalothin resistant, 74%; gentamicinresistant, 79%; tetracyclifi3~ refistant, 76%; erythromycin resistant, 84%; clindamycin resistant,73%; of loxacin resisrant, 75%; sulfamethoxazole-trimethoprim (cotrimoxazole) resistant, 6%;ohlorarnphenicol resistant, 3%; vancomIFcin resistant (VRSA), 0%. From minimum inhibitoryconcentrations (MICs) of 107 5. aureus strains from hospital patients in 2000, the resistancerates were as follows; penicillin resistant, 99%, oxacillin resistant (MRSA), 80%; erythromycinresistant, 83%; tetracycline resistant, 76%; gentamicin resistant, 71%, cephalothin resistant, 79%;of loxacin resisrant, 79%; vancomycin resistant (VRSA), 0%. The resistance rates of 5. aureusstrains from hospital patients by disc diffusion and MfC were similar. From disc diffusion 4eston 130 nasal 5. aureus isolats from 498 healthy volunteers of the community, the resistancerates were as follows; penicil;lin resistant, 9j%; oxacillin resistant (MRSA), 2%; erythromycinresistant, 213%; tetracyc)me resistant, 22%; gentamicin resistant, 11%, cephalothin resistant, 1%;clindamycin resistant, 2%, of loTacin resisrant, 0%; sulfamethoxazole-trimethoprim(cotrimoxazole) resistant, 0%; ·Thlorarnphenicol resistant, 1%; amoxicillin-cavulanic acid resistant,1%; yancomycin resistant (VRSA), 0%. Summarily, in the community 2% of nasal 5. aureusisolates were tfRSA, and tht resistance rates of nasal 5. aureus isolates were high in theorder of penicillin (95%), erythrom?cin (f8%), tetracycline (22%), gentamicin (11%).

Charcaterization of sweetpotato orange gene (IbOr) responsible for accumulation of carotenoids

Sun Ha Kim,Young Ock Ahn,Jae Cheol Jeong,Haeng Soon Lee,Mi Jeong Ahn,Sang Soo Kwak 한국육종학회 2011 한국육종학회 학술발표회 발표요지 Vol.43 No.-