Genome-wide investigation of a Korean synthetic breed, Woori-Heukdon using the Illumina PorcineSNP60K BeadChip

Yong‑Min Kim,Ha‑Seung Seong,Jung‑Jae Lee,Da‑Hye Son,Jin‑Su Kim,Soo‑Jin Sa,Young‑Sin Kim,Tae‑Jeong Choi,Kyu‑Ho Cho,Joon‑Ki Hong,Jung‑Woo Choi,Eun‑Seok Cho 한국유전학회 2020 Genes & Genomics Vol.42 No.12

Background: Woori-Heukdon (KWH) is a Korean synthetic pig breed generated using Chookjin-Duroc (KCD), Chookjin-Chamdon (KCC), and their crossbreds. Currently, there is a severe lack of studies investigating the Korean breed populations including wild boars (KWB) throughout the genome. Objective: This study was performed to investigate the genetic characteristics of Korean pig populations at the genome-wide level. Methods: Using the SNP dataset derived from genotyped and downloaded datasets using the Illumina PorcineSNP60K BeadChip, we compared the genomes of 532 individuals derived from 23 pig breeds to assess the genetic diversity, inbreeding coefficient, genetic differentiation, and population structure. Results: KWB showed the lowest average expected heterozygosity (HE = 0.1904), while KWH showed the highest genetic diversity (HE = 0.02859) among Korean populations. We verified that the genetic composition of KWH, showing USD of 74.8% and KCC of 25.2% in ADMIXTURE analysis. In population structure analyses, KCC was consistently shown to be separated from other pig populations. In addition, we observed gene flow from Western pigs to a part of Chinese populations. Conclusion: This study showed that Korean native pigs, KCC have genetic differences in comparison with Chinese and Western pigs; despite some historical records and recent genetic studies, we could not find any clear evidence that KCC was significantly influenced by Chinese or Western breeds in this study. We also verified the theoretical genomic composition of KWH at the molecular level in structure analyses. To our knowledge, this is the first genomic study to investigate the genomic characteristics of KWH and KCC.

종단분석을 이용한 세계 자동차산업의 전략적 제휴 특성 : A Longitudinal Analysis

조대우,송우용 충남대학교 경상대학부설 경영경제연구소 1999 경영논집 Vol.15 No.2

세계 자동화산업은 1990년대 이후 전략적 제휴와 M&A를 통한 대규모적인 구조변화가 가속화되고 있다. 본 연구는 지난 20년간 세계 자동차산업에서 발생된 전략적 제휴의 특성을 종단면적으로 분석하였다. 분석결과 첫째, 불안정적인 자동차산업의 환경 하에서 다른 기업과 협력을 통한 보완적 자원을 획득하되, 상황의 변화에 대한 대응성을 높여 전략적 유연성을 확보하기 위하여 비지분형 제휴의 비중이 커지고 있으며, 둘째, 양방향적 제휴가 증가하고 있어 기업간 의존관계가 보다 증폭되고 있음을 확인하였고, 셋째, 자동차 기업간의 협력 및 경쟁관계가 보다 복잡하게 전개되고 있으며, 범세계적인 규모에서의 보편적인 전략으로 정착되고 있었다.

유입 바베시아증 1예

우준희,조용균,김은옥,채종일,김양수,양성연,유지소,이성순 대한감염학회 1997 감염 Vol.29 No.1

최근 외국으로의 여행이 빈번해지면서 유입 감염되는 경우가 많아지고 있는 추세이며 임상 증세가 말라리아와 유사하여 다소 진단이 어려울 수가 있어 한번쯤 바베시아증을 생각하는 것이 바람직하겠다. 저자들은 아프리카에 다녀온 뒤 나타난 바베시아증을 경험하였기에 문헌고찰과 함께 보고하는 바이다. Babesiosis is a tick-borne, malaria-like illness caused by Babesia species that infect erythrocytes of mammals incidentally. The family Babesiidae is characterized by consisting of nonpigmented intraerythrocytic parasites that reproduce within erythocytes by asynchronous, asexual budding into two or four daughter cells (tetrad). We experienced a case of human babesiosis presenting fever and chills. The patient was a 49-year old man, who had been in Africa (Ethiopia, Uganda). Three weeks before admission intermittent spiking fever had developed, which had been accompanied by severe chills. The peripheral blood smear (Giemsa-stain) revealed characteristic forms of a intracellular quadraple parasite compatible with Babesia. The patient was improved significantly by the treatment with quinine and clindamycin for a week.

축차확률비 검정을 이용한 실제값과 Wald 근사값의 정확도에 관한 연구

조규민,조건호,박용우 대구대학교 산업기술연구소 1993 産業技術硏究 Vol.12 No.-

Sequential analysis refers to techniques for testing hypotheses or estimating parameters when the sample size is not fixed in advance but is determined during the course of the experiment by criteria which depend on the observations as they occur. In this paper, We considered the properties of Wald approximations in S.P.R.T. and compared exact value with the Wald approximations by using a example and then found the error probabilities α_(0),α₁and expected sample size (average sample number) E(N) by S.P.R.T in AR(1). Conclusively, We discovered that Wald approximations tend to over-estimate the true error probabilities.

Tetramethylenediamine에 의한 아크릴纖維의 改質에 관한 硏究

趙龍錫,許萬宇,李光祐 대구효성가톨릭대학교 1989 연구논문집 Vol.39 No.1

To study the possibility of modifcation of acrylic fiber, Cashmilon SF was treated with tetramethylenediamine (TMDA) in toluene without catalyst. And dye adsorption dyed with Benzyl Scarlet BS and tenacity of modified acrylic fiber were measured. Following results were obtained, 1. Cashimilon was reacted with TMDA by condensaton reaction at above 130℃. 2. Acrylic fiber treated with TMDA could be dyed by acidic dyes. 3. The tenacity of acrylic filber treated with TMDA was decreased, so the pilling of the fiber will lessen.

반송용 편측식 선형기기의 추력제어에 의한 특성해석

우정인,신동률,조용길,노태균 東亞大學校 大學院 1999 大學院論文集 Vol.24 No.-

본 논문에서는 PWM 인버터 구동 편측식 선형유도 전동기(이하 SLIM)의 공간백터 제어와 PI 제어를 통한 추력 제어를 행한다. 1차측 권선과 SLIM의 2차측 구조 사이에서 발생하는 공극길이의 떨림은 빠른 응답특성을 얻기위해서 최소화 되어야 한다. 먼저, SLIM의 전압방정식이 추력과 수직력 특성을 해석하기 위하여 d-q축 등가회로로서 나타내어진다. 또한, d-q축 등가회로의 모델링과 해석은 등가회로상에서 전류변동에 따른 강인한 과도 추력특성을 얻을 수 있다. 지령속도와 추력에 의한 SLIM의 직접구동 결과는 실험을 통해서 확인된다.

깁스표본기법을 이용한 와이블분포의 위험률에 대한 베이즈추정

조건호,이우동,신양규,윤용화 慶山大學校 基礎科學硏究所 1998 基礎科學 Vol.2 No.1

와이블분포를 따르는 표본을 이용하여 위험률을 베이지안 방법을 이용하여 추정한다. 깁스표본법을 베이지안 추정에서 사후확률의 분포를 구하는 방법에 적용하여 위험률에 대한 사후분포와 주변사후분포를 추정하는 방법을 제안한다. 그리고, 9개의 가솔린 정류에서 쓴 sdufwjsekfrlrn(heat exchanger)에 대한 수명시간자료를 이용하여 제안된 방법으로 위험률에 대한 베이즈추정량을 구하고 최우추정량과 비교한다. In this paper, a Bayesian estimation of the hazard rate function of Weibull distribution is considered. Using Gibbs sampling approach, the posterior distribution of hazard and Bayes estimator of hazard are presented. Using 9 heat exchanger data, the proposed method is illustrated.

교류여자방식 브러시리스 동기전동기의 공간벡터에 의한 토오크제어

우정인,정영일,노태균,조용길,신동률 東亞大學校 附設 情報通信硏究所 1997 情報通信硏究所論文誌 Vol.5 No.1

In the paper, a vector control method for a AC-excited BLSM(Brushless Synchronous Motor) is proposed. The BLSM has a feature that separate exciter is not needed for excitation. The proposed method is described in two parts as follow, one is the design of drive and the other is a modeling for its imlpementation. Rotor flux is estimated using inditect sensing method based on voltage equation in the synchronously rotation reference frame. And rotor position os calculated from rotor angular velocity and stator current. Through computer simulation results of this prorosed system, it is shown that the BLSM drive has a ability of precision torque control from the static and dynamic performances.

韓國企業의 換危險 情報管理 特性 : 期間比較分析 A Longitudinal Analysis

趙大宇,宋宇鏞 충남대학교 경상대학부설 경영경제연구소 1994 경영논집 Vol.10 No.1

정신보건관련시설 입원(소)자의 주요 정신장애 유병률 : 전국 20개 시설의 입원(소)자를 대상으로

조성진,조맹제,서동우,함봉진,홍진표,배재남,이준영,이동우,박종익,전홍진,김성주,김용익 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.6

Objectives : One of the objectives of this study is to estimate the prevalence rates of psychiatric diagnoses in the combined populations of psychiatric hospitals, psychiatric nursing facilities and homeless asylums using the Korean version of the Composite International Diagnostic Interview (K-CIDI), which is a comprehensive and fully standardized interview schedule to assess psychiatric disorders for diagnosis. The Other objective is to compare with previously studied prevalence rates of Psy-chiatric diagnoses using the results of this study. Methods : The study subjects, aged from 181o 64 years, were randomly selected from 64,582 institutionalized population of psychiatric hospitals, Psychiatric nursing facilities and homeless asylums as of 30, June, 2001. Twelve trained interviewers administered the K-CIDI to the selected respondents. A total of 1,875 respondents (male 1,194, female 681) completed the interview. Results : The lifetime and one year prevalences of any diagnosis excluding nicotine dependence · withdrawal, anxiety disorder, eating disorder, somatoform disorder were 88.2% (male 88.1%, female 88.3%), and 65.8% (male 62.7%, female 73.7%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were 78.5% (male 75.3%, female 83.7%), and 56.8% (male 51.9%, female 64.8%), respectively. The lifetime and one year prevalences of alcohol use disorder (dependence/abuse) were 26.7% (male 37.9%, female 8.3%), and 8.7% (male 12.8%, female 2.1%), respectively. The lifetime and one year prevalences of mood disorder were 18.1% (male 13.5%, female 25.8%), and 10.4% (male 7.2%,female 16.9%), respectively. The lifetime and one year prevalences of schizophrenia and other psychotic disorders were comparable with the 2001 community survey by 1.19% to 1.32%, and 0.51% to 0.61%, respectively. The lifetime and one year prevalences of schizophrenia were also comparable by 0.16% to 0.28%, and 0.16% to 0.25%, respectively. There were no significant changes of prevalence rates when correction were applied to other psychiatric diagnosis. Conclusion : The results of this study could be used for evaluating the distribution of psychiatric diagnoses in mental health related facilities and for planning mental health policies.