韓國産 脣形(꿀풀)科 植物에 關한 本草學的 硏究

盧炳圭,金裕鎭,金台睍,宋昊埈,辛民敎 한국전통의학연구소 1999 한국전통의학지 Vol.9 No.1

A Herbalogical Study in the Plants of Labiatae in Korea. For the purpose of developing Korean Herbgalogy with the plants of Labiatae which grow wild and is planted in korea, the these and writings on herbalogy, from literature of successive generations, have been throughly investigative and the results obtained were as follows: 1. There were totaled to 27 genera and 86 species in Korea and among them medical plants are 24 genera, 59 species, some 68% in total but, the number of species may be added because of the similar plants. 2. According to the oriental names which can be used for medical purpose, the medical plants belonging to the Labiatae family were classified as Herba 29, Radix 4, Fructus 3, Folium 2, Lignum 2, Semen 1 and Flos 1. 3. According to sum of 86 species in Labiatae family, they were classified into Scutellaria genera 10, Salvia genera 6, Ajuga genera 5, Clinopodium genera 5, Elsholtzia genera 5 and Mosla 5. Thus it was noticed that Scutellaria genera was the main kind, some 12% in total. 4. According to the number of species of the original plants about each chinese materia medicals, they were classified into HERBA AGASTACHIS 5 and HERBA AJUGAE, HERBA SCUTELLARIAE, HERBA LYCOPI 3 each. 5. According to nature and flavour of medical plants, they were classified into warmth, heat: 20 each, cold, cool: 16 each, balance 4 and unidentified 2. Thus it was noticed that warmth and heat is the main in nature and flavour medicinal plants. 6. According to the Properties and Principal curative action, they were classified into drugs for clearing up heat and toxin 8, drugs for clearing up heat and dispelling pathogenic heat from blood, drugs for clearing up heat and heatstroke 3 each, drugs for activating the blood and removing blood stasis, drugs which is sudorific and pungent in nature and flavour for dispelling wind and cold in the treatment of exterior symptom complex 4 each. Thus it was noticed that drugs for clearing up heat was the main kind. 7. Comparing to whole medical plants 42 kinds, toxic drugs include minor toxin were 3 kinds, 7% of the whole. Thus toxic drugs were rare. From this result, it was revealed that the plants for medical purpose in Labiatae was 68% of the whole, in which HERBA was mostly abundunt and toxic plants was so rare that it will be used for clinical treatment more easily. It is considered that many experiements and clinical approches must be continued to use Labiatae plants widely.

부정류 흐름을 이용한 부유물질 확산모형에 관한 연구

민병형,이승휘,민일규,유갑용,임대영 東亞大學校 海洋資源硏究所 1996 硏究論文集 Vol.9 No.1

To investigation the diffusion of suspended material we use a 3-D unsteady numerical model based on the Euler method. We applied the model to mainstream of Nak Dong River confluence of Miryang river place at KyungNam kimhae-Si Saenglim-Myon Masa-Ri. We pridicted the concentration of suspended material due to dredging at a near by water-supply intake.

악성림프종 환자에서 복합화학요법으로 유발된 백혈구 감소증에 대한 인형 재조합 과립구 집락형성-촉진인자(rhG-CSF: Neutrogin)의 효과

박성규,전진우,기신영,유병우,김홍수,백승호,원종호,홍대식,박희숙 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

Clinical effects of rhG-CSF were investigated in 17 patients receiving chemotherapy for non-Hodgkin's lymphoma. Patients were given G-CSF 2㎍/㎏/day after 2nd cycle chemotherapy for least 14 consecutive days, and clinical and laboratory results were compared to results of the first cycle. Treatment with G-CSF resulted in increase of mean WBC count(952.9±152.2㎜³vs 1882.4±350.4/㎜³) and neutrophil count(212.9±53.0/㎜³vs 841.5±238.0/㎜³), reduced the duration of leukocytopenic days(12.4±1.3 days vs 5.5±1.0 days, WBC count less than 4000/㎜³) and neutropenic days(4.5±0.9 days vs 2.3±0.7 days, neutrophil count less than 500/㎜³), and reduced the duration of neutropenic fever(5.8±1.1 days vs 0.9±0.5 days). The side effects of G-CSF were not so significant. These results demonstrated that G-CSF is safe and useful for the treatment of neutropenia induced by anticancer chemotherapy of non-Hodgkin's lymphoma and reducing the incidence of febrile periods and duration of antibiotic administration.

河床變動 豫測에 관한 硏究 : 密陽江이 合流하는 洛東江 本流地域을 中心으로

閔丙亨,李承輝,閔一圭,兪甲鎔,吳尙龍 동아대학교 건설기술연구소 1996 硏究報告 Vol.20 No.1

In this study, when we collect river bed sediment at the point where mainstream of Nak Dong river join branch of Mil Yang river, the change of river bed around downstream area was estimated and based on experimental data using three dimensional unsteady flow model about the water level to quantity of water and velocity and river bed change through numerical imitation experiment and hydraulic model experiment.

PIV의 수리학 분야에의 적용

윤병만,유권규,노영신 명지대학교 산업기술연구소 2001 産業技術硏究所論文集 Vol.20 No.-

This paper introduces PIV technique which can be used for velocity measurement in hydraulic engineering field. Some examples are presented : measurement of surface velocity using LSPIV ; measurement of flow characteristics and fall-velocity measurement using PTV. Results show that PIV can be applied widely to hydraulic engineering measurements, not only in the laboratory but also in the field.

저수시 하상상황에 따른 조도계수의 적용에 관한 연구

조성만,유상호,박병선,민일규,민병형 東亞大學校 海洋資源硏究所 2002 硏究論文集 Vol.14 No.1

As the roughness coefficient by existing manning table is used by technician's experience and judgement, it isn't always correct. This study as a try to make quantitative roughness coefficient is to suggest a new application mode computerizing roughness coefficient by surveying the velocity and hydraulic condition of small rivers. The bound of roughness coefficient was 0.027∼0.180 and its values distribute uniformly. This means that the roughness coefficient adapt value Manning table cannot fill up the transformed value when the small rivers are low. The roughness coefficient computation mode in this study with hydraulic radius(R), channel slope(I), average grain diameter(D) as subject factors presents as follows. n = 5.97R^0.671 l^0.452 D^0.059

中學 科學敎育의 探究學習에 대한 評價問項 開發(Ⅰ)

奇宇恒,權炳奎,朴德圭,이병교,鄭遠佑,金裕漢 경북대학교 과학교육연구소 1984 科學敎育硏究誌 Vol.8 No.-

The purpose of this study is to achieve the individualized inquiring learning which is centered on students by improving the method of the evaluation of the inquiry learning in the science class in a multi-student class. Therefore the author made the table of specification for scientific achievements of the abilities of inquiring by analyzing the abilities of inquiring according to the content of science and five basic experiments of each unit inthe first grade of of middle school, ant then made the paper and pencil and performance test items for the evaluation of the abilities of inquiring. The paper and pencil test was taken after the experimental and observational class, and performance test was taken in the way of the students' self evaluation, peer evaluation and Tester evaluation. The results are as follows: 1) In operation of the inquiry learning by two experiments, performance test items and 13 the paper and pencil test items made for evaluation of the abilities of inquiring could be applied usefully. 2) Correlation coefficient between paper and pencil test and performance test is .362 and it is very low. Therefore it is desirable that performance test be used for the evaluation for the abilities of inquiring which cannot be evaluated by paper and pencil test. 3) In evaluation of the abilities of inquiring by performance test on five basic experiments, it is more desirable that 'the use of microscope' is presented in the way of peer evaluation or peer and Tester evaluation, 'the observation on epidermis of onion cell' in the way of peer evaluation, and self-evaluation. 4) Skill of the abilities of inquiring in experimental and observational class can be evaluated correctly through performance test.

장중첩증을 동반한 맹장 지방종 1예

홍의실,나병규,김민옥,유일영,채지영,채희복,윤세진,이상전,송형근,박길선,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

대장 지방종은 주로 우측 결장에 호발하고 특히 회맹판 부위와 맹장 부위에 호발한다. 또한 50~60대에 빈도가 높고 증상이 있는 환자에서 장중첩증이 높게는 40~50%에서 보고되고 있어 성인 장중첩증의 원인으로 중요한 비중을 차지한다. 특히 성인 장중첩증 및 장폐쇄의 중요 원인인 악성 종양과 임상 양상이 유사하여 감별진단이 중요하다. 저자들은 반복적인 복통을 주소로 내원한 환자에서 맹장의 4×5㎝의 점막하 지방종이 말단 회장부위와 반복적인 장중첩중이 발생했던 1례를 부분 절제술로 치료하여 양호한 임상 경과를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Lipomas are one of the most common benign nonepithelial tumors of the colon which are often detected incidentally by radiologic investigation or on operation. These tumors are usually without specific symptoms. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve and the cecum. Most patients are asymptomatic. but tumors larger than 2 cm tend to produce a change in bowel habit. abdominal pain. rectorrhagia and complications including luminal obstruction or intestinal intussusception. Diagnosis can be made by colonoscopy abdominal CT. MRI, or barium enema. We report a case of lipoma of the cecum that originated in the submucosa and presented as a intussusception in a 50-year-old woman with a brief review of the literature.

鹽油中 呈味成分의 檢索

金香仙,金賢榮,朴吉子,劉炳淑,李揆媛,洪璟珠 梨花女子大學校 藥學硏究所 1961 梨花藥學硏究 Vol.- No.2

아세클로페낙 연질캡슬(클란자 에스 연질캡슬)의 개발

용철순,이경희,최진석,박병주,정세현,김용일,박상만,배명수,김귀자,김영식,유창훈,강성룡,유봉규,이종달,최한곤 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.1

To develop and aceclofenac soft capsule, four preparations with various solubilizers were prepared and their dissolution test was carried out. Among four preparations tested, a preparation with ethanolamine was selected a formula of aceclofenac soft capsule (Clanza S^(™), since it showed the fastest dissolution rate. Bioequivalence of aceclofenac tablet, Airtal^(™)(Dae-Woong Pharmaceutical Co., Ltd.) and aceclofenac soft capsule, Clanza S^(™)(Korea United Pharmaceutical Co., Ltd.) was evaluated according to the guideline of KFDA. Fourteen normal male volunteers (age 20-25 years old) were divided into two groups and a randomized 2×2 cross-over study was employed. After oral administration of one tablet or capsule containing 100 ㎎ of aceclofenac, blood ws taken at predetermined time intervals and the concentration of aceclofenac in plasma wa determined with an HPLC method under UV detector. The pharmacokinetic parameters (C_(max), T_(max) and AUC_(t)) were calculated and ANOVA was utilized for the statistical analysis of parameters using logarithmically transformed AUC_(t), C_(max) and T_(max) between Airtal tablet and Clanza soft capsule were 2.89%, 0.18% and 43.0%, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.250(e.g.log(0.81) - log(1.23) and log(0.89) - log(1.14)) for AUC_(t) and C_(max), respectively. Thus, the criteria of the KDFA guidelines for the equivalence was satisfied, indicating that Clanza S^(™) soft capsule is bioequivalent to Airtal^(™) tablet.