로타 초음파 검사에서의 초음파 평가 결함크기와 실결함 크기와의 관계

성운학,김정태,박윤식 한국비파괴검사학회 2003 학술대회 논문집 Vol.- No.1

In order to evaluate the reliability of rotor forgings, it is very important to know the actual size of the defects in the rotor forgings. The determination of the defect size requires the accurate non-destructivc measurement. However, there may be some differences between the reported size with the ultrasonic non-destructive testing method and the actual size of defects. These differences may be a severe cause of errors in evaluation of rotor forgings. So, the calculated size with "Master Curve" considering safety factor, which is usually larger than the reported size, has been used in evaluation of rotor forgings. The relation between EFBH (Equivalent Flat Bottom Hole) size measured by non-destructive method and the actual size by destructive method in many rotors manufactured at Doosan was investigated. In this investigation, "Master Curve" compensating the differences between UT reported size and actual size of defects in our rotor forgings was obtainable. The applicability of this "Master Curve" as a way of calculating the actual defect sizc was also investigated. For the evaluation of rotor forgings, it is experted that this "Master Curve" may be used to determine the accurate actual size of defects.

라텍스개질 콘크리트의 물-시멘트비에 따른 건조수축 특성

정원경,김성환,김동호,이주형,이봉학 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.A

Drying shrinkage cracking which may be caused by the relatively large specific suface is a matter of grave concern for latex modified concrete(LMC) overlay and rapid-setting cement latex modified concrete(RSLMC) overlay. LMC and RSLMC were studied for field applications very actively in terms of strength and durability in Korea. However, there were no considerations in drying shrinkage. Therefore, the purpose of this dissertation was to study the drying shrinkage properties of LMC and RSLMC with the main experimental variables such as cement types(ordinary portland cement, rapid setting cement), water-cement ratios and curing days at a same controlled environment of 60% of relative humidity and 20℃ of temperature. The drying shrinkage for specimens was measured with a digital dial gauge of Demec. The test results showed that the drying shrinkage of LMC and RSLMC were considerably lower with low water-cement ratio, respectively. This might be attributed to the interlocking of hydrated cement and aggregates by a film of latex particles, water retention due to hydrophobic, and colloidal properties of the latexes resulting in reduced water evaporation.

Phage Display 기법을 이용한 B형 간염 바이러스 Polymerase의 Rnase H 활성을 억제하는 인간 단세포군 항체의개발

이성락,송은경,정영주,이영이,김익중,최인학,박세광 Official Journal of the Korean society for immunol 2004 Immune Network Vol.4 No.1

LMC로 보강된 철근 콘크리트 보의 부착파괴 거동에 관한 실험적 연구

이봉학,김성환,정원경,김현오 강원대학교 부설 석재복합신소재 제품연구센터 2004 석재연 논문집 Vol.9 No.-

이 논문은 동일 조건에서 양생되어진 LMC 보강 철근 콘크리트의 특성 및 보강 효과에 대하여 연구되었다. 이때 변수는 스터럽의 유무와 보강높이를 변화하여 실험을 실시하였다. 시험편돌의 처짐과 철근의 변형은 보의 중심에서 다이얼 게이지 그리고 스트레인 게이지로 측정되었다. 실험 결과는 LMC의 철근 콘크리트가 OPC의 것보다 상당히 높은 초기 균열 하중을 보여주었다. 이것은 라텍스 필림 막에 의해 수화한 시멘트와 골재의 맞물림 작용에 기인할 수 있다. 라텍스의 추가는 균열 하중을 상당히 줄일 수 있었고, 극한 강도, 철근 변형, 처짐은 일반 콘크리트의 것과 유사하게 측정되어, LMC로 압축부 및 인장부를 보강할 경우 보강효과가 있는 것을 알 수 있었다. The purpose of this study was to study the reinforced concrete beam properties of LMC with the main experimental variables such as concrete types(ordinary portland cement concrete, latex modified concrete), the use of stirrup and curing days at the same controlled environment of 60 % of relative humidity and 20 ℃ of temperature. The deflection and steel's strain for specimens were measured with a dial gauge and strain gauge at the center of beam. The test results showed that the reinforced concrete of LMC was considerably higher initial cracking load than that of OPC. This might be attributed to the interlocking of hydrated cement and aggregates by a film of latex particles, water retention due to hydrophobic, and colloidal properties of the latexes resulted in reduced water evaporation. As a result, the addition of latex would be able to reduce considerably cracking load. However, similar to ultimate strength, steel strains, and deflection of concrete than that of OPC. It may be considered that reinforcing steel affected in the concrete beam than that of concrete.

유한요소 해석을 이용한 현장 콘크리트 부착강도 측정조건

김성환,정원경,권 혁,김현오,이봉학 江原大學校 産業技術硏究所 2002 産業技術硏究 Vol.22 No.A

The performance of old and the new concrete construction depends upon bond strength between old and the new concrete. Current adhesive and strength measurement method ignores the effect of stress concentration from shape of specimens. Therefore, this research calculates stress concentration coefficient as the ratio of drilling depth to drilling diameter(h_s/D), the ratio of overlay thickness to drilling diameter(h_o/D), the ratio of steel disk thickness to drilling diameter(t/D), the ratio of overlay elastic modulus to substrate modulus(E_l/E_0), the distance from core to corner border(L_corner) and the distance between cores(L_core) vary. The finite element method is adapted to analysis. The results from the F.E.M analysis are as follows : The stress concentration effects can be minimized when the ratio of drilling depth to drilling diameter(h_s/D) is 0.20∼0.25, the elastic modulus ratio(E_l/E_0) is 0.6~1.0, and the ratio of steel disk thickness to drilling diameter(t/D) is 3.0. The overlay thickness, the distance from specimens to corner border(L_corner), the distance between cores(L_core) almost do not affect to the stress concentration.

지방척수수막류 14례의 임상 분석 : Clinical Analysis of 14 Cases

이정호,신규만,김명현,송준혁,박향권,김성학,박동빈 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.6

Lipomyelomeningocele is the most common malformation leading to spinal cord tethering. Nonetheless, these lesion continues to pose a challenge in patient management. The purpose of this study was to identify the clinical feature, candidate for surgical repair, and outcome of lipomyelomeningocele in young children and adults. We studied the magnetic resonance images and/or lumbar myelo-CT of lipomyelomeningocele performed between January 1987 and September 1995 at our institutions and reviewed the pertinent medical records and radiologic studies to determine clinical feature, surgical candidate, and outcomes of these patients. Of the 14 cases(11 female and 3 males) studied, the most common factor that caused these patients to seek help was the cosmetic effect of the mass on their back, followed by urinary incontinence, and weakness of lower extremities. The patients' age ranged from 2 months to 21 years(mean, 5.0 years). All the patients underwent immediate surgical management that consisted of removal of lipoma, untethering of the cord, and complete dural sac repair. Follow up for these patients ranged from 6 to 82 months(median, 54 mo). None of the patients that underwent surgical correction before the emergence of neurological deficit had ever developed neurological deficits at the end of the follow up. However a few of the patients, despite presented with neurological deficits or urinary incontinence at the time of surgery, improved significantly. In conclusion, early detection and prophylactic surgery is imperative to prevent permanent neurological deficits and urinary dysfunction.

스쿠알렌 합성 유전자를 도입한 형질전환 가시오가피

서진욱,정재훈,최용의,이학성,신차균 중앙대학교 유전공학연구소 2003 遺傳工學硏究論集 Vol.16 No.1

The enzyme, squalene synthase, represents a branch point in the isoprenoid pathway capable of diverting carbon flow specifically to the biosynthesis of phytosterol and Triterpenoid. Transgenic Eleutherococcus senticosus plants were prepared by introducing the genes for squalene synthase derived from Panax ginseng (PgSS1), hygromycin phosphotransferase (HPT) and green fluorescent protein (GFP) through Agrobacterium-mediated transformation. Establishment of transgenic plantlets were confirmed by the presence of PgSS1 and HPT bands in the genomic DNA preparation using a PCR method and a Southern blotting. In addition, expression of the introduced GFP DNA was confirmed by observing green fluorescence of GFP from the embroyos. In the in vitro analysis of the PgSS1 enzymatic activities the transgenic plants showed to have 1.5 to 3 times higher than wild type plant, indicating that the PgSS1 genes was well over-expressed in the transgenic plants. Especially the PgSS1 acivities of embroyogenic cell was 120 times higher than those of plantlet.

흡연에 의한 급성 호산구성 폐렴 2예

박종빈,김학렬,주현준,유태양,신성남,신정현,송정섭,황기은,김소영,양세훈,정은택 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

최근 흡연을 시작한 젊은 성언에서 급성 호산구성 폐렴의 발생에 대한 증례가 보고되고 있다. 급성 호산구성 폐렴은 대개 발열을 동반하기 때문에 초기에는 감염성 폐렴으로 잘못 진단, 치료되는 경우가 많다. 아직 정확한 병태 생리 및 조직학적 소견은 밝혀져 있지 않지만 병력 청취 및 임상 양상, 방사선 소견의 관찰을 통해 급성 호산구성 폐렴을 의심하고, 진단을 위해 기관지 폐포 세척액 검사를 시행한다면 좀 더 쉽게 진단 내릴 수 있을 것이다. 본 저자들은 최근 처음 시작한 흡연에 의해 발생한 급성 호산구성 폐렴을 진단하고, 스테로이드를 투여하여 성공적으로 치료한 환자 2예를 경험하였기에 이를 문헌 고찰과 함께 보고하는 바이다. Acute eosinophilic pneumonia(AEP) is characterized by acute febrile respiratory illness associated with diffuse pulmonary infiltration and pulmonary eosinophilia. The specific etiology for acute eosinophilic pneumonia is elusive. By some investigators, cigarette smoking is suggested as a causative substance which can cause AEP. In recent, the authors experienced two cases of AEP following cigarette smoking. Both cases had characteristic features including age around 20 years, new onset smoking before occurance of AEP, diffuse infiltration on chest radiography, pulmonary eosinophilia based on bronchoalveolar lavage and acute improvement after steroid therapy. These clinical features are resemble with previous smoking induced AEP case reports. Base on these clinical features, cigarette smoking associated AEP could be diagnosed more easily.

제주산 보통온주의 저온저장

梁相互,高正殷,金聖學,高正三 濟州大學校 亞熱帶農業硏究所 1994 亞熱帶農業硏究 Vol.11 No.-

제주산 청도온주의 저온저장조건을 검토하였다. 저장기간 중 3월 하순까지는 과피수분, 가용성고형물, 총당, 비타민 C, 비중의 변화가 매우 적었으며, 부패율이 20%수준으로서 비교적 신선도를 유지한 상태에서 저장이 가능한 것으로 보였다, 그러나 그 이후에는 온도가 낮을수록 냉해증상이 심하게 일어나 부패과의 발생이 많아지면서 저장이 어려웠다. 또한, 중량감소, 경도의 저하, 산함량의 저하는 저장기간동안 계속하여 서서히 일어났다. 온주밀감의 경우 저온에서 장기간 저장이 어려움을 알 수 있어서 저장용 감귤의 특성을 고려하여 저장조건을 설정할 필요가 있었다. The conditions of cold stroage of Citrus aoshima unshiu produced in Cheju were investigated. The changes of peel moisture content, soluble solids, total sugar, vitamin C and density were slightly occured, and decay ratio was below 20% on keeping freshness relatively till late of March during cold storage. After that, decayed citrus fruits were increased from cold injury with lower temperature. The loss of fruit weight, decrease of fruit hardness, and decrease of acid content were occured gradually during cold stroage. Because of the difficulty of long term storage for Citrus unshiu, the conditions and periods of cold storage would be determined after considering the physicochemical properties of fruits every year.

Multiple myeloma 환자에서 Bortezomib치료 후 발생한 마비성 장폐색증 1례

김준영,이원식,손창학,박성길,진한영,박석주,조영완,정은욱,강명주,박정하,주영돈 인제대학교 2006 仁濟醫學 Vol.27 No.-

Bortezomib is the first clinically available proteasome inhibitor that is clinically effective in the treatment of multiple myeloma. A proteasome inhibitor acts through multiple mechanisms to arrest tumor growth, tumor spread, and angiogenesis. The main adverse effects of bortezomib are gastrointestinal symptoms, cytopenia, fatigue, and peripheral neuropathy. To date, severe paralytic ileus has not been reported as a toxic effect of bortezomib treatment in multiple myeloma. Bortezomib is a novel agent that has only been used clinically for 30 months, so a need exists to further evaluate its toxicity. We report a case of grade Ⅲ (NCI CTCAE v3.0) or grade Ⅳ(SWOG toxicity criteria) paralytic ileus in a 65-year-old man with relapsed multiple myeloma who underwent one cycle of single-agent bortezomib treatment scheduled in a 21-day cycle (1.3 mg/㎥ as a single i.v. bolus on days 1, 4, 8, and 11).