http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
이길홍,나철,이영식,이창훈,노병인,홍창권,Lee, Kil-Hong,Na, Chul,Lee, Young-Sik,Lee, Chang-Hoon,No, Byung-In,Hong, Chang-Kwon 한국정신신체의학회 2000 정신신체의학 Vol.8 No.1
연구목적 : 여성 및 남성 탈모중의 개인적 특성이나 탈모양상, 정신의학적특성, 동반 신체질환 및 치료 방법에 관한 비교 분석을 통해 여성 탈모증의 치료 및 예방 지침을 수립하기 위해 연구를 시도 하였다. 방법 : 1998년 1월부터 12월까지 중앙대학교 용산병원 피부과에 내원하여 정신과로 의뢰된 여성 탈모증 환자 51명을 연구집단으로, 남성 탈모증환자 42명을 대조군으로 선정하여 남녀별 차이를 비교 분석하였다. 수집된 자료는 SPSS-$PC^+$ 9.0V 프로그램을 통해 자료 처리를 하였고, 집단간의 차이는 교차 분석 및 변량 분석을 통해 비교 분석하였다. 결과 : 1) 여성일수록 남성에 비해 경제 수준이나 교육 수준이 낮고, 하류 직종에 종사하며, 부친이 무직자가 많고, 형제 자매 수가 많으며, 여자형제만 있는 비율이 높다. 2) 여성일수록 피부과 내원빈도가 많고, 최근 두정부나 전두부 탈모가 많으며, 여성가족 중에 탈모 경험자가 많은 반면에 남성 가족중에는 탈모자가 적고, 후두부 탈모가 적으며, 손톱의 변화는 적다. 3) 여성일수록 가정내 갈등이나 경제적 변화로 인해 스트레스를 받고, 가정내 갈등이나 내성적 성격으로 인해 갈등을 겪는 반면 직장문제나 건강 변화 등 생활 변동을 겪거나, 작업 수행 능력의 부진으로 인한 갈등은 적고 직장 적응에 있어 어려움을 겪는 비율도 낮다. 4) 여성일수록 우울증이나 전환장애가 많고, 불안 증상들이나 우울 증상들을 흔히 호소하며, 불안수준이 높은 반면 신체화증상이나 강박증상은 덜 호소하며, 불안장애는 적다. 5) 여성일수록 남성에 비해 내향화 성향이나 허구 성향 억압 성향 여성화 성향이 높다. 6) 여성일수록 관절염이나 비뇨생식계장애가 많은 반면 위장관장애나 지루성피부염은 적다. 7) 여성일수록 etizolam이나 tretinoin은 많이 사용하는 반면 향정신성 의약품은 적게 사용하며, 특히 clotiazepam이나 prednicarbonate를 적게 사용한다. 결론 : 여성 탈모증 환자는 남성 환자에 비해 우울증이 많고, 불안 및 우울 증상을 흔히 호소하며, 가정 문제로 인해 발병하고, 내향화 성향이나 허구 성향, 억압 성향, 여성화 성향이 높다. 이 결과는 여성 환자가 남성 환자에 비해 더 심각한 정신병리를 보여 준다는 것을 의미하고, 여성 탈모의 예방 및 치료를 위해 정신과적 개업이 필요함을 말해 주고 있다. 따라서 피부과 의사들은 병발하는 정신장애에 대해 깊은 관심을 갖고, 정신과와 피부과가 공동 치료 계획을 세워야 한다. Objectives : The present study was performed to reveal differences between female and male cases of alopecia in their alopecia related variables such as patterns of hair loss, psychiatric characteristics, associate illnesses, and methods of treatment, and to use them as basic materials for proper management and early prevention of the alopecia prone cases. Methods : In order to analysis the gender difference in hair losses, the subjects were divided into two subgroups as the 51 cases of female alopecia and the 42 cases of male alopecia, who had visited to the department of psychiatry consulted from the department of dermatology, Yongsan hopital, ChungAng University, Seoul, Korea, from January 1998 to December 1998. In data analysis, the subjects were statistically assesed by chi-squre test and analysis of varaiance, through SPSS-$PC^+$ 9.0V. Results : 1) Female subjects were more likely showed lower socio-economical level including lower eonomical level, lower educational level, or lower occupational level in their parent's job, were more likely to have larger number of siblings and to have many sisters comparison to the male cases. 2) Female subjects were more likely visited to the department of dermatology, more history of alopecia in their female family members, lesser history of alopecia in their male family members, more loss of hairs in vertex or frontal region of scalp, lesser loss of hairs in occipital region, and lesser nail changes in comparison to the male cases. 3) Female subjects were more suffered from intra-familial conflicts and economical changes, or their introverted personality makeup, lesser likely suffered from changes of business and health changes, and showed lesser conflicts related with poorer adaptaion in their job life. 4) Female subjects were more likely diagnosed as depression or conversion disorders, more frequently complaint anxiety symptoms or depressive symptoms, higher level of anxiety index, lesser complaint somatization or obsessive compulsive symptoms, and lesser diagnosed as anxiety disorder in comparison to the male cases. 5) Female subjects were more likely tended to show personality makeup such as the introverted, the lie, the repressed, or the feminine trends than the male cases. 6) Female subjects were more significantly treated by antianxiety drug such as etizolam and dermatological therapies include tretinoin, and lesser treated by clotiazepam and prednicarbonate in comparison to the male cases. Conclusion : From the facts that The most important factors in developing hair loss in the female subjects in comparison to the male cases seems to be closely correlated with the serious psychopathology such as the presence of mental disorders including depression, the presence of complaining anxiety or depressive symptomatology, the presence of stressful life events such as intrafamilial life changes, and the presence of personality makeup such as the introverted, the lie, the repressed, or the feminine trends, the authors confirmed that dermatologists act as the primary care physician are in a unique position to recognize psychiatric comorbidity and execute meaningful intervention for female patients with the alopecia with psychiatrists.
B형 만성 간염 환자에서 인터페론 단독 요법과 인터페론과 라미부딘 병합 요법의 비교
정은미,홍창권,오성욱,박재완,이준성,김경철,김배영,홍성표,박필원,임규성,김세현,황성규,Jeong, Eun-Mi,Hong, Chang-Kwon,Oh, Seong-Wook,Park, Jae-Wan,Lee, June-Sung,Kim, Kyung-Chul,Kim, Bai-Young,Hong, Sung-Pyo,Park, Pil-Won,Rim, Kyu-Sung,Kim 대한임상약리학회 2000 臨床藥理學會誌 Vol.8 No.1
Background/Aims: Hepatitis B virus (HBV) is associated with clinically significant chronic infection that may lead to the development of cirrhosis or even hepatocellular carcinoma. However, interferon alpha is effective in only 25-40% of chronic hepatitis B patients. The purpose of this study was to evaluate the effectiveness of interferon and lamivudine combination treatment comparing with interferon alone. Methods : Twenty patients with chronic hepatitis B(moderate to severe activity) were randomized to with interferon alone (11 patients) or combination (9 patients) therapy for 24 weeks. The patients were monthly evaluated, biochemically and serologically. Results : There was no statistical difference between both groups in HBeAg seroconversion rate and ALT normalizaion rate at the end of treatment. But, HBV DNA suppression rate was significantly higher in combination group (100%) than the interferon alone group (54%). No serious side effects were noted in both groups. Conclusion : Combinaton therapy with alpha interferon plus lamivudine given for 24 weeks appears safe and is well tolerated. But, combination therapy was no more efficient than interferon alone in HBeAg seroconversion except HBV DNA suppression rate during the treatment period.
여인권 ( In Kwon Yeo ),현무열 ( Moo Yeol Hyun ),박미경 ( Mi Kyung Park ),박귀영 ( Kui Young Park ),이갑석 ( Kapsok Li ),김범준 ( Beom Joon Kim ),서성준 ( Seong Jun Seo ),김명남 ( Myeung Nam Kim ),홍창권 ( Chang Kwun Hong ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.7
Papular elastorrhexis is a rare disorder, possibly a form of multiple elastic tissue nevi. The disorder typically presents as several asymptomatic, firm, nonfollicular, 1- to 5-mm-diameter, and well-demarcated white papules. It predominantly appears on the trunk, including the chest, abdomen, back and shoulders, upper extremities, and, rarely, thighs. Histologically, it is characterized by substantial fragmentation or nearly complete loss of elastic tissue in the reticular dermis. We report a 37-year-old female with popular elastorrhexis, which developed on a rare site, only dorsal aspect of the hand and foot with no involvement of the proximal extremities. (Korean J Dermatol 2012;50(7):618∼620)
Dermoscopy를 보조적으로 이용하여 진단한 구강편평태선
여인권 ( In Kwon Yeo ),김현규 ( Hyun Kyu Kim ),김동하 ( Dong Ha Kim ),박귀영 ( Kui Young Park ),이갑석 ( Kap Sok Li ),김범준 ( Beom Joon Kim ),서성준 ( Seong Jun Seo ),김명남 ( Myeung Nam Kim ),홍창권 ( Chang Kwun Hong ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.2
Lichen planus is a relatively common chronic inflammatory disease of the skin, mucous membranes, and hair follicles. Oral lichen planus develops in any area of the oral mucosa, especially in the buccal mucosa, tongue, gingiva and lip. The cutaneous lesions of lichen planus are characterized with gray or white punta or streaks, referred to as Wickham striae. We report 53-year-old woman with lichen planus on the lower lip diagnosed by dermoscopy. (Korean J Dermatol 2012;50(2):167~170)
장게실염에 병발한 간문맥과 장관막정맥 내 가스 및 혈전증
이준성(June Sung Lee),홍창권(Chang Kwon Hong),김경철(Kyung Chul Kim),홍성표(Sung Pyo Hong),황성규(Seong Gyu Hwang),박필원(Pil Won Park),임규성(Kyu Sung Rim),김종우(Jong Woo Kim),김희진(Hee Jin Kim) 대한소화기학회 2000 대한소화기학회지 Vol.36 No.3
The diagnosis of acute colonic diverticulitis and the assessment of its severity may be difficult. Especially, in the elderly patients with it, immediate diagnosis and initiation of therapy greatly influence the outcome. Pericolonic abscess and fistula formation, perforation, luminal obstruction, and peritonitis are well- known complications of diverticulitis. Rarely, the inflammatory process can extend into the venous drainage of the affected portion of the colon. Ultrasonography is a newly used imaging modality in patients under the suspicion of acute colonic diverticulitis and its complications. We experienced a case of colonic diverticulitis of which delayed diagnosis resulted in the development of portal and mesenteric vein gas and thrombosis. The literature on portal and mesenteric venous gas associated with colonic diverticulitis is reviewed, and the usefulness of ultrasound as a rapid, noninvasive tool to diagnose this rare condition is discussed. (Kor J Gastroenterol 2000;36:408 - 412)
저칼륨혈증성 주기성 마비로 발현한 원발성 쇼그렌 증후군
정은미 ( Eun Mi Jeong ),권건호 ( Kun Ho Kwon ),홍창권 ( Chang Kwon Hong ),김형태 ( Hyung Tae Kim ),김경수 ( Kyung Soo Kim ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.2
We describe a 46-year-old woman with hypokalemic paralysis as the initial manifestation of Sjogren`s syndrome. Sjogren`s syndrome is an autoimmune exocrinopathy, characterized by keratoconjuntivitis sicca and xerostomia. Among the extraglandular manifestations of Sjogren`s syndrome, renal tubular involvement, especially renal tubular acidosis, is the most often latent or minimally symptomatic. Renal tubular acidosis is estimated to be present in 25~30 percent of the cases. Hypokalemic paralysis may serve as a clinical marker for more severe renal disease in patient who has primary Sjogren`s syndrome with renal tubular acidosis, even though it is a rare manifestation of Sjogren`s syndrome.
김현규 ( Hyun Kyu Kim ),여인권 ( In Kwon Yeo ),김동하 ( Dong Ha Kim ),박귀영 ( Kui Young Park ),이갑석 ( Kap Sok Li ),서성준 ( Seong Jun Seo ),홍창권 ( Chang Kwun Hong ),송계용 ( Kye Yong Song ) 대한피부과학회 2012 大韓皮膚科學會誌 Vol.50 No.2
Necrobiotic xanthogranuloma (NXG) is a rare, progressive, histiocytic disease characterized by destructive cutaneous lesions, a close association with paraproteinemia, multiple myeloma, hypertension, and multiple extracutaneous manifestations. Multiple indurated yellow-red plaques or nodules are commonly present in this disorder. The pathogenesis of NXG is poorly understood. Histopathologically, NXG features with hyaline necrosis or necrobiosis are present. We describe a patient with typical cutaneous and histologic findings of NXG with an associated monoclonal gammopathy. (Korean J Dermatol 2012;50(2):152~155)
신장이식술을 받은 환자에서 cyclosporine 투여 후 재발한 Kaposi 육종 1 예
정유선(You Son Chong),서성준(Seong Jun Seo),송계용(Kye Yong Song),홍창권(Chang Kwon Hong) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.7
Kaposi`s sarcoma is an unusual neoplasm that has proved to be an enigma in many ways since its original description by Kaposi in 1872. Of the several different type of Kaposi`s sarcoma, iatrogenically immunosuppressed patients predisposed to Kaposi`s sarcoma are usually either transplant recipients or patients receiving immunosuppressive therapy. We report a case of recurrent Kaposi`s sarcoma in a 56 year old male, which has occurred during the cyclosporine therapy of kidney transplantation. Cyclosporine was discontinued and chemotherapy began and the resolution of Kaposi`s sarcoma has been obtained. Cyclosporine maintenance therapy was started again for the prevention of graft rejection. But 1 year later, Kaposi`s sarcoma recurred probably due to re-use of cyclosporine.