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조수연,조수연,허일영,고재수,진성호,강혜진 대한병리학회 2012 Journal of Pathology and Translational Medicine Vol.46 No.2
Synovial sarcoma arises in the para-articular tissues, and it can also occur in various unexpected sites. We report a rare case of primary monophasic synovial sarcoma (MSS) arising in the mesentery. A 59-year-old man presented with a palpable abdominal mass. On microscopic examination, the entire tumor comprised a dense proliferation of the spindle cells without epithelial components. The tumor cells were positive for transducin-like enhancer of split 1, bcl-2, epithelial membrane antigen and CD99 but negative for CD34, CD117, alpha-smooth muscle actin, cytokeratin, and calretinin on immunohistochemistry. The reverse transcriptase-polymerase chain reaction revealed a single 151-bp fragment representing the SYT-SSX2 fusion transcript. Because mesenteric MSS is extremely rare and many cases display histologic findings that overlap with those of more frequently involved tumors such as hemangiopericytoma and gastrointestinal stromal tumor, there is a chance of making an incorrect diagnosis that can result in an inappropriate treatment.
조수연,배웅진,조용현,이승주 대한감염학회 2009 감염과 화학요법 Vol.41 No.1
Background : Acute bacterial prostatitis is an uncommon male urinary tract infection that is the result of severe prostatic infection mainly by gram-negative bacteria. We conducted a retrospective study to report clinical outcomes of patients with acute bacterial prostatitis. Materials and Methods : The clinical records of 49 patients diagnosed with acute bacterial prostatitis were reviewed retrospectively and patients' symptoms, investigations, and treatments were analyzed. Results : All patients presented with fever and voiding symptoms. Some patients (22.4%) had a history of prior manipulation of the lower urinary tract including transrectal prostate biopsy. Urine cultures were positive for 51% of the patients. The most common pathogen was Escherichia coli (60%), followed by Pseudomonas aeruginosa (20%) and Staphylococcus aureus (12%). The ciprofloxacin susceptibility against E. coli was 80%. All patients were treated with parenteral antibiotics in the hospital followed by oral antibiotics for average of three weeks. The major drugs used for empirical treatment were cephalosporins, aminoglycosides, and fluoroquinolones. Prostatic abscess was found in two (4.1%) Patients and chronic pelvic pain syndrome developed in six (12.2%) patients during follow-up. Conclusion : The currently used empirical antibiotics were mostly effective in the treatment of acute bacterial prostatitis. Continuous monitoring on antimicrobial susceptibility of acute bacterial prostatitis was necessary for providing proper treatment guideline.
중학생의 NEO 청소년 성격특성과 스마트폰 중독 취약성의 관계: 문제 중심적 스트레스 대처방식의 매개효과
조수연,안귀여루 한국청소년학회 2018 청소년학연구 Vol.25 No.4
본 연구는 중학생들을 대상으로 NEO 청소년 성격특성과 스마트폰 중독의 취약성과의 관계를 알아보고, 문제 중심적 스트레스 대처방식이 성격유형과 스마트폰 중독의 취약성 사이에서 매개효과가 있는지를 밝히고자 하였다. Y시에 있는 중학생 250명을 대상으로 설문조사를 실시하였고, 그중 성실하게 답변한 175부를 분석대상으로 확정하였다. 연구결과 NEO 청소년 성격특성의 하위요인 중 신경증이 스마트폰 중독 취약성에 영향을 미치는 것으로 나타났으며, 문제 중심적 스트레스 대처방식이 NEO 성격특성 중 신경증과 스마트폰 중독의 취약성을 부분 매개하는 것으로 나타났다. 중학생들의 스마트폰 중독 실태를 파악하고 청소년들의 스마트폰 중독 예방을 위해 청소년들의 성격특성과 문제 중심적 스트레스 대처방식을 고려하는 것이 필요하다는 점을 밝혀낸 것이 본연구의 주요 의의이다. 마지막으로 본연구의 제한점과 시사점을 논의하였다. This study focused on the relationship between the vulnerability of smart-phone addiction and NEO adolescents’personality traits of middle school students, and mediating effect of problem focused stress coping strategies. A survey was conducted on 250 middle school students of Y City. The 175 of the surveys, which were responded diligently, were decided as the subject of analysis. The result of this study showed that the neuroticism, which is the sub-factor of the NEO adolescents’personality, has an effect on the vulnerability of smart-phone addiction, and the problem focused stress coping strategies partially meditate the neuroticism, which is one of the NEO adolescents’personality traits, and the vulnerability of smart-phone addiction. Identifying the actual condition of smart-phone addiction of middle school students, who have high addiction rate, and finding out the need of considering adolescents’personality trait and problem focused stress coping strategies in order to prevent adolescents’ smart-phone addiction are the main significances of this study. Finally limitations and implications were discussed.
비정상 자궁 출혈에 대한 익위승양탕가감방(益胃升陽湯加減方)을 포함한 한방 치험 6례
조수연,김동철,Cho, Su-Yun,Kim, Dong-Chul 대한한방부인과학회 2017 大韓韓方婦人科學會誌 Vol.30 No.4
Objectives: This paper aim to report the effects of korean medical treatment including Yikwiseungyang-tang-gagambang on patients with abnormal uterine bleeding. Methods: From 2012 August to 2017 June, six outpatient with abnormal uterine bleeding came to the clinic. The patients took Yikwiseungyang-tang-gagambang and got acupuncture and warm needle therapy. We assessed the patients' bleeding period and bleeding amount. Results: All patients' abnormal uterine bleeding stopped after they took Yikwiseungyang-tang-gagambang in 2~40 days. One patient restart slight bleeding, the bleeding stopped after continual korean medical treatment. Conclusions: Korean medical treatment including Yikwiseungyang-tang-gagambang is effective on patients with abnormal uterine bleeding.
조수연,이주미,김혜림,신경화,이현지,장철훈,김형회 대한진단검사의학회 2017 Annals of Laboratory Medicine Vol.37 No.2
Background: ABO blood typing in pre-transfusion testing is a major component of the high workload in blood banks that therefore requires automation. We often experienced discrepant results from an automated system, especially weak serum reactions. We evaluated the discrepant results by the reference manual method to confirm ABO blood typing. Methods: In total, 13,113 blood samples were tested with the AutoVue system; all samples were run in parallel with the reference manual method according to the laboratory protocol. Results: The AutoVue system confirmed ABO blood typing of 12,816 samples (97.7%), and these results were concordant with those of the manual method. The remaining 297 samples (2.3%) showed discrepant results in the AutoVue system and were confirmed by the manual method. The discrepant results involved weak serum reactions (<2+ reaction grade), extra serum reactions, samples from patients who had received stem cell transplants, ABO subgroups, and specific system error messages. Among the 98 samples showing ≤1+ reaction grade in the AutoVue system, 70 samples (71.4%) showed a normal serum reaction (≥2+ reaction grade) with the manual method, and 28 samples (28.6%) showed weak serum reaction in both methods. Conclusions: ABO blood tying of 97.7% samples could be confirmed by the AutoVue system and a small proportion (2.3%) needed to be re-evaluated by the manual method. Samples with a 2+ reaction grade in serum typing do not need to be evaluated manually, while those with ≤1+ reaction grade do.