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모기질 세포종의 흡인 세포학 - 전이성 암종으로 오진된 2예 보고 -
고재수,하창원,조경자,장자준,Koh, Jae-Soo,Ha, Chang-Won,Cho, Kyung-Ja,Jang, Ja-June The Korean Society for Cytopathology 1993 대한세포병리학회지 Vol.4 No.1
35세 및 22세 여자의 경부에 생긴 종괴의 세침흡인 세포학적 검사에서 악성이 의심되는 병변 및 악성 병변으로 오진되었던 모기질 세포종 2예의 세포학적 소견을 기술한다. 핵 세포질의 비율이 높고 뚜렷한 핵소체를 보이는 기저양 세포, 농염성 핵을 가진 각화된 편평상피세포, 이물형 거대세포 및 괴사성 배경을 보였고, 후속하여 보았을 때 이러한 소견은 모기질 세포종의 특이적인 소견으로서 악성 종양으로 보기에는 염색질의 분포가 균질하고 핵들의 다형성이 없는 점이 악성 종양과는 구별되는 소견이었고, 모기질 세포종은 경부 종괴 및 여하한 부위의 피하 종괴의 세침 흡인에서 상기의 소견을 보일 때 감별 진단의 하나로서 고려해야한 양성 병변이다. We describe cytologic findings of two cases of pilomatrixoma which had been cytologically misdiagnosed as suspicious malignant and malignant lesions in 35 year-old and 22 year-old females who presented a palpable neck mass. The cytologic smears showed many basaloid cells with a high nuclear-cytoplasmic ratio, nuclear hyperchromatism and prominent nucleoli, keratinized squamous cells with pyknotic nuclei, foreign body giant cells, and chronic inflammatory cells in necrotic back-ground. Retrospective view of this aspiration smear revealed that these findings were characteristic features of pilomatrixoma, and the evenly distributed chromatin pattern as well as the lack of nuclear pleomorphism were considered to be the differential points from malignant neoplasm. Pilomatrixoma is a benign neoplasm which should be included in differential diagnosis if the fine needle aspiration cytologic smear of a neck mass or subcutaneous mass of any site showed these features.
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고재수,진민선,강신광,김민석,최희승,이정은,김길호,전대근 대한병리학회 2010 Journal of Pathology and Translational Medicine Vol.44 No.2
Background : The Src family kinases (SFKs) are involved in multiple aspects of tumorigenesis, such as, proliferation, migration, and angiogenesis, and are involved in the generation and progression of many types of tumors. Furthermore, dasatinib, a general SFKs inhibitor was recently approved for use in chronic myeloid leukemia. This study was performed to evaluate the expression of Lyn, a member of the SFKs, in osteosarcoma tissues. Methods : One hundred and sixteen patients with osteoblastic osteosarcoma were selected for Lyn expression analysis. The correlation between Lyn expression in tumor sections and patients’ clinicopathologic characteristics and the prognostic significance of Lyn expression were evaluated. Results : Lyn was found to be expressed in 52 of the 116 patients (44.8%), and Lyn positive tumor was found to be significantly associated with a lytic tumor pattern on plain radiographs (p = 0.04). Furthermore, those positive for Lyn showed longer metastasis free survival (5-year metastasis free survival, 65.2% for Lyn positive and 46.8% for Lyn negative; p = 0.06), though this was only marginally significant. Conclusions : Lyn was found to be overexpressed in osteosarcoma tissues, and this overexpression was found to be correlated with osteolysis.
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고재수,Koh, Jae-Soo 대한세포병리학회 2008 대한세포병리학회지 Vol.19 No.1
The major categories of neuroendocrine tumors of lung are typical carcinoid, atypical carcinoid, large cell neuroendocrine carcinoma, and small cell carcinoma. The histologic classification criteria of neuroendocrine tumors are well documented in the "WHO Classification of Tumors" based on mitotic figures and necrosis. Cytologic characteristics of neuroendocrine tumors are trabecular, acinar, and solid arrangement of tumor cells and occasional rosette formation. Nuclear chromatin patterns are characteristically described as "salt and pepper chromatin pattern". Many of cytologic classifications documented in the literature are before the "WHO Classification". In this review, the cytologic features of pulmonary neuroendocrine tumors are documented according to the WHO classification, and recent concepts of neuroendocrine tumors of lung are discussed.
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Novel isolate DC-DC converters with current circulating circuit for electronic/hybrid car and UPS
고재수,조은석,이용근 한국전시산업융합연구원 2015 한국과학예술융합학회 Vol.19 No.-
Full-bridge, Push-Pull, Flyback and Forwardconverters are generally used for electronic/hybridcar and UPS(Uninterrupted Power Supply). In thispaper, we proposed novel Full-bridge, Push-Pull,Flyback and Forward converters. In the designtopologies, the proper inductor was added in orderto make the circulating current even during deadtime period, so that we can achieve the betterproperties such as higher efficiency, cheaper price,with same output properties as the conventionalconverters. The proposed topologies simulated byPSpice.
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고재수 高神大學校 1987 論文集 Vol.15 No.-
성령으로의 세례라는 문제는 20세기 이전에는 많이 토론된 문제가 아닌 것 같다. 그것은 성령론 자체가 무시되었다는 뜻이 아니다. 개혁신학에만 제한시켜 보더라도 칼빈은 기독교강요 네 권 중 셋째 권에서 성령론을 다루었고 그래서 성령의 신학자란 별명을 얻었다.
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고재수 高神大學校 1986 論文集 Vol.14 No.-
성경에 대한 성령의 증거에 관해 웨스트민스터 신앙고백은 세가지를 언급하고 있다. 곧 교회의 증거, 성경 자체의 증거, 성령 증거이다. 이 중 교회의 증거는 도입적인 것이다. 대부분의 사람들은 교회의 인도를 받아 성경의 권위를 알게 된다. 교회의 증거의 결과로써 우리는 성경을 고귀하게 볼 수 있다는 것이다. 하지만 고귀함 그 자체는 성경을 하나님의 말씀으로 인정하는 것이 되지는 못한다. 또한 교회의 증거가 그러한 고귀함을 가져다 주는 일은, 가능하겠지만 그 결과까지 확실히 보장하지는 못한다. 성경 자체 증거로는 성경이 하나님의 말씀인 사실을 보여주기 위해 여러가지의 매우 무게있는 논증들을 제시하고 있음을 본다. 그러나 어떤 이유 때문에 그 자체 증거는 우리의 확신을 이루지 못한다. 성경이 하나님의 말씀이라는 확신은 성령의 증거만이 생기게 할 수 있다.
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"Atypical Squamous Cells of Undetermined Significance"의 질적 분류와 조직 소견과의 비교
고재수,정진행,이승숙,조경자,Koh, Jae-Soo,Chung, Jin-Haeng,Lee, Seung-Sook,Cho, Kyung-Ja 대한세포병리학회 1999 대한세포병리학회지 Vol.10 No.1
To evaluate whether different qualifications of a cytologic diagnosis of "atypical squamous cells of undetermined significance(ASCUS)" predict a greater or lesser likelihood of tissue diagnosis of uterine cervix, we compared different cytologic qualifications of ASCUS with the tissue diagnosis. One hundred twenty-two consecutive Papanicolaou smears showing ASCUS in women who had undergone cervical biopsy within nearest 30 days were collected. The 122 smears were qualified as "favor reactive"(25%), "favor low grade squamous intraepithelial lesion (LSIL)"(24%), "favor squamous intraepithelial lesion(SIL)"(16%), "favor high grade squamous intraepithelial lesion(HSIL)"(16%), and "not otherwise specified"(19%). Squamous intraepithelial or invasive lesion was pathologically confirmed by cervical biopsy in 13%, of the "favor reactive", 27% in "favor LSIL", 70% in "favor SIL", 75%, in "favor HSIL", and 35% in "not otherwise specified" smears. There were significant associations between the favor reactive smear and the benign biopsy finding and between the favor SIL smear and the biopsy shewing a squamous intraepithelial or more severe lesion. Nevertheless, most of favor LSIL smears exhibit reactive process in tissue biopsy. Conclusively, qualified ASCUS stratifies women Into different risk groups for SIL. The cytopathologist should make the cytologic diagnosis of "ASCUS, favor LSIL" circumspectly.
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